46 Publications (Page 1 of 2)
2017
Population pharmacokinetics of cefepime in febrile neutropenia: implications for dose-dependent susceptibility and contemporary dosing regimens.
Rhodes, Nathaniel JGrove, Meagan EKiel, Patrick JO'Donnell, J NicholasWhited, Laura KRose, Dusten TJones, David R and Scheetz, Marc H
International journal of antimicrobial agents, June 28, 2017. | Journal Article
2016
Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.
Masters, Andrea RMasters, Andrea RGufford, Brandon TGufford, Brandon TLu, Jessica Bo LiLu, Jessica Bo LiMetzger, Ingrid FMetzger, Ingrid FJones, David RJones, David RDesta, Zeruesenay and Desta, Zeruesenay
The Journal of pharmacology and experimental therapeutics, vol. 358, (no. 2), pp. 230-238, August 2016. | Journal Article
 
Methotrexate polyglutamate monitoring in patients with Crohn's disease.
Fischer, MonikaSiva, ShiviCook, Gwendolyn KJones, David R and Fadda, Hala M
Clinical pharmacology in drug development, June 8, 2016. | Journal Article
 
Pharmacokinetics of Cefepime in Patients with Cancer and Febrile Neutropenia in the Setting of Hematologic Malignancies or Hematopoeitic Cell Transplantation.
Whited, LauraGrove, MeaganRose, DustenRhodes, Nathaniel JScheetz, Marc HO'Donnell, J NicholasNeeb, JessicaThoele, KelliJones, David RLowe, ChristopherMoore, Dawn and Kiel, Patrick J
Pharmacotherapy, August 6, 2016. | Journal Article
 
Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.
Gufford, Brandon TGufford, Brandon TLu, Jessica Bo LiLu, Jessica Bo LiMetzger, Ingrid FMetzger, Ingrid FJones, David RJones, David RDesta, Zeruesenay and Desta, Zeruesenay
Drug metabolism and disposition: the biological fate of chemicals, vol. 44, (no. 4), pp. 544-553, April 2016. | Journal Article
 
Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS.
Masters, Andrea RMcCoy, MichaelJones, David R and Desta, Zeruesenay
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, vol. 1015-1016, pp. 201-208, March 15, 2016. | Journal Article
 
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Hertz, Daniel LDeal, AllisonIbrahim, Joseph GWalko, Christine MWeck, Karen EAnderson, StevenMagrinat, GustavOlajide, OludamilolaMoore, SusanRaab, RachelCarrizosa, Daniel RCorso, StevenSchwartz, GarryGraham, MarkPeppercorn, Jeffrey MJones, David RDesta, ZeruesenayFlockhart, David AEvans, James PMc Leod, Howard LCarey, Lisa A and Irvin, William J
The oncologist, vol. 21, (no. 7), pp. 795-803, July 2016. | Journal Article
 
Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer.
Lee, JiyoonLee, JiyoonLee, JiyoonYakubov, BakhtiyorYakubov, BakhtiyorYakubov, BakhtiyorIvan, CristinaIvan, CristinaIvan, CristinaJones, David RJones, DavidJones, DavidCaperell-Grant, AndreaCaperell-Grant, AndreaCaperell-Grant, AndreaFishel, MelissaFishel, MelissaFishel, MelissaCardenas, HoracioCardenas, HoracioCardenas, HoracioMatei, DanielaMatei, Daniela and Matei, Daniela
Neoplasia (New York, N.Y.), vol. 18, (no. 11), pp. 689-698, October 25, 2016. | Journal Article
2015
In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.
Hertz, Daniel LSnavely, Anna CMc Leod, Howard LWalko, Christine MIbrahim, Joseph GAnderson, StevenWeck, Karen EMagrinat, GustavOlajide, OludamilolaMoore, SusanRaab, RachelCarrizosa, Daniel RCorso, StevenSchwartz, GarryPeppercorn, Jeffrey MEvans, James PJones, David RDesta, ZeruesenayFlockhart, David ACarey, Lisa A and Irvin, William J
British journal of clinical pharmacology, vol. 80, (no. 5), pp. 1122-1130, November 2015. | Journal Article
 
Nicotine and Cotinine Exposure from Electronic Cigarettes: A Population Approach
de Mendizábal, NievesJones, DavidJahn, AndyBies, Robert and Brown, Joshua
Clinical Pharmacokinetics, vol. 54, (no. 6), pp. 615-626, Jun 2015. | Journal Article
 
Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.
Jousma, EdwinJousma, E.Rizvi, Tilat ARizvi, T.A.Wu, JianqiangWu, J.Janhofer, D.Janhofer, DavidDombi, EvaDombi, E.Dunn, Richard SDunn, R.S.Kim, M. O.Kim, Mi-OkMasters, A.R.Masters, Andrea RJones, David RJones, D.R.Cripe, Timothy PCripe, T.P.Ratner, Nancy and Ratner, N.
Pediatric blood & cancer, vol. 62, (no. 10), pp. 1709-1716, October 2015. | Journal Article
2014
A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007
Miller, KathyAlthouse, SandraNabell, LisleRugo, HopeCarey, LisaKimmick, GretchenJones, DavidMerino, Maria and Steeg, Patricia
Breast Cancer Research and Treatment, vol. 148, (no. 1), pp. 99-106, Nov 2014. | Journal Article
2013
Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum.
Decker, Brian SO'Neill, Kalisha DChambers, Mary ASlaven, James EYu, ZhangshengJones, David R and Moe, Sharon M
Clinical pharmacology : advances and applications, vol. 5, pp. 193-9, 2013. | Journal Article
 
In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies.
Farag, Sherif SSrivastava, ShivaniMessina-Graham, StevenSchwartz, JenniferRobertson, Michael JAbonour, RafatCornetta, KennethWood, LisaSecrest, AngieStrother, R MJones, David R and Broxmeyer, Hal E
Stem cells and development, vol. 22, (no. 7), pp. 1007-15, 2013/Apr/1. | Journal Article
 
Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.
Tandra, SwetaChalasani, Naga PJones, David RMattar, SamerHall, Stephen D and Vuppalanchi, Raj
Annals of surgery, vol. 258, (no. 2), pp. 262-9, 2013/Aug. | Journal Article
 
Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis.
Vuppalanchi, RajVuppalanchi, RajVuppalanchi, RajVuppalanchi, RajLiang, TiebingLiang, TiebingLiang, TiebingLiang, TiebingGoswami, Chirayu PankajGoswami, Chirayu PankajGoswami, Chirayu PGoswami, Chirayu PankajNalamasu, RohitNalamasu, RohitNalamasu, RohitNalamasu, RohitLi, LangLi, LangLi, LangLi, LangJones, DavidJones, DavidJones, DavidJones, DavidWei, RongrongWei, RongrongWei, RongrongWei, RongrongLiu, WanqingLiu, WanqingLiu, WanqingLiu, WanqingSarasani, VishalSarasani, VishalSarasani, VishalSarasani, VishalJanga, Sarath ChandraJanga, Sarath ChandraJanga, Sarath CJanga, Sarath ChandraChalasani, NagaChalasani, NagaChalasani, Naga and Chalasani, Naga
PloS one, vol. 8, (no. 9), pp. e74471, 2013. | Journal Article
 
Use of dried plasma spots for the quantification of iothalamate in clinical studies.
Hagan, Andrew SJones, David R and Agarwal, Rajiv
Clinical journal of the American Society of Nephrology : CJASN, vol. 8, (no. 6), pp. 909-14, 2013/Jun. | Journal Article
2012
A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.
Zhang, ShengLiu, SijiuTao, RongyaWei, DanChen, LanShen, WeihuaYu, Zhi-HongWang, LinaJones, David RDong, Xiaocheng C and Zhang, Z. F
Journal of the American Chemical Society, vol. 134, (no. 43), pp. 18116-24, 2012/Oct/31. | Journal Article
 
A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic.
Haas, David MQuinney, Sara KMcCormick, Catherine LJones, David R and Renbarger, Jamie L
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 25, (no. 4), pp. 419-23, 2012/Apr. | Journal Article
 
Subcutaneous 5-Azacitidine Treatment of Naturally Occurring Canine Urothelial Carcinoma: A Novel Epigenetic Approach to Human Urothelial Carcinoma Drug Development
Hahn, Noah MBonney, Patty LDhawan, DeepikaJones, David RBalch, CurtisGuo, ZhongminHartman-Frey, CorieFang, FangParker, Heidi GKwon, Erika MOstrander, Elaine ANephew, Ken and Knapp, Deborah W
Journal of Urology, vol. 187, (no. 1), pp. 302-309, 2012. | Journal Article
2011
A phase I trial of high-dose clofarabine, etoposide, and cyclophosphamide and autologous peripheral blood stem cell transplantation in patients with primary refractory and relapsed and refractory non-Hodgkin lymphoma.
Srivastava, ShivaniJones, DavidWood, Lisa LSchwartz, JenniferNelson, Robert PAbonour, RafatSecrest, AngieCox, ElizabethBaute, JaySullivan, CherylKane, KathleenRobertson, Michael J and Farag, Sherif S
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, vol. 17, (no. 7), pp. 987-94, 2011/Jul. | Journal Article
 
Contribution of N-Glucuronidation to Efavirenz Elimination In Vivo in the Basal and Rifampin-Induced Metabolism of Efavirenz
Cho, Doo-YeounOgburn, Evan TJones, David R and Desta, Zeruesenay
Antimicrobial Agents & Chemotherapy, vol. 55, (no. 4), pp. 1504-1504, 2011. | Journal Article
 
Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity.
Cai, ShanbaoCai, ShanbaoWang, HaiyanWang, HaiyanBailey, BarbaraBailey, BarbaraErnstberger, AaronErnstberger, AaronJuliar, Beth EJuliar, Beth ESinn, Anthony LSinn, Anthony LChan, Rebecca JChan, Rebecca JJones, David RJones, David RMayo, Lindsey DMayo, Lindsey DBaluyut, Arthur RBaluyut, Arthur RGoebel, W SGoebel, W ScottPollok, Karen E and Pollok, Karen E
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 17, (no. 8), pp. 2195-206, 2011/Apr/15. | Journal Article
 
Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
Fishel, Melissa LFishel, Melissa LJiang, YanlinJiang, YanlinRajeshkumar, N VRajeshkumar, N VScandura, GlendaScandura, GlendaSinn, Anthony LSinn, Anthony LHe, YingHe, YingShen, ChangyuShen, ChangyuJones, David RJones, David RPollok, Karen EPollok, Karen EIvan, MirceaIvan, MirceaMaitra, AnirbanMaitra, AnirbanKelley, Mark and Kelley, Mark R
Molecular cancer therapeutics, vol. 10, (no. 9), pp. 1698-708, 2011/Sep. | Journal Article
 
Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.
Wang, FangWang, FangLi, JingLi, JingSinn, Anthony LSinn, Anthony LKnabe, W EKnabe, W. EricKhanna, MayKhanna, MayJo, InhaJo, InhaSilver, Jayne MSilver, Jayne MOh, KyungsooOh, KyungsooLi, LiweiLi, LiweiSandusky, George ESandusky, George ESledge, George WSledge, George WNakshatri, HarikrishnaNakshatri, HarikrishnaJones, David RJones, David RPollok, Karen EPollok, Karen EMeroueh, Samy and Meroueh, Samy O
Journal of medicinal chemistry, vol. 54, (no. 20), pp. 7193-205, 2011/Oct/27. | Journal Article