46 Publications (Page 1 of 2)
2017
Population pharmacokinetics of cefepime in febrile neutropenia: implications for dose-dependent susceptibility and contemporary dosing regimens.
Rhodes, Nathaniel J⋅Grove, Meagan E⋅Kiel, Patrick J⋅O'Donnell, J Nicholas⋅Whited, Laura K⋅Rose, Dusten T⋅Jones, David R and Scheetz, Marc H
International journal of antimicrobial agents, June 28, 2017. | Journal Article
2016
Chiral Plasma Pharmacokinetics and Urinary Excretion of Bupropion and Metabolites in Healthy Volunteers.
Masters, Andrea R⋅Masters, Andrea R⋅Gufford, Brandon T⋅Gufford, Brandon T⋅Lu, Jessica Bo Li⋅Lu, Jessica Bo Li⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Jones, David R⋅Jones, David R⋅Desta, Zeruesenay and Desta, Zeruesenay
The Journal of pharmacology and experimental therapeutics, vol. 358, (no. 2), pp. 230-238, August 2016. | Journal Article
 
Methotrexate polyglutamate monitoring in patients with Crohn's disease.
Fischer, Monika⋅Siva, Shivi⋅Cook, Gwendolyn K⋅Jones, David R and Fadda, Hala M
Clinical pharmacology in drug development, June 8, 2016. | Journal Article
 
Pharmacokinetics of Cefepime in Patients with Cancer and Febrile Neutropenia in the Setting of Hematologic Malignancies or Hematopoeitic Cell Transplantation.
Whited, Laura⋅Grove, Meagan⋅Rose, Dusten⋅Rhodes, Nathaniel J⋅Scheetz, Marc H⋅O'Donnell, J Nicholas⋅Neeb, Jessica⋅Thoele, Kelli⋅Jones, David R⋅Lowe, Christopher⋅Moore, Dawn and Kiel, Patrick J
Pharmacotherapy, August 6, 2016. | Journal Article
 
Stereoselective Glucuronidation of Bupropion Metabolites In Vitro and In Vivo.
Gufford, Brandon T⋅Gufford, Brandon T⋅Lu, Jessica Bo Li⋅Lu, Jessica Bo Li⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Jones, David R⋅Jones, David R⋅Desta, Zeruesenay and Desta, Zeruesenay
Drug metabolism and disposition: the biological fate of chemicals, vol. 44, (no. 4), pp. 544-553, April 2016. | Journal Article
 
Stereoselective method to quantify bupropion and its three major metabolites, hydroxybupropion, erythro-dihydrobupropion, and threo-dihydrobupropion using HPLC-MS/MS.
Masters, Andrea R⋅McCoy, Michael⋅Jones, David R and Desta, Zeruesenay
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, vol. 1015-1016, pp. 201-208, March 15, 2016. | Journal Article
 
Tamoxifen Dose Escalation in Patients With Diminished CYP2D6 Activity Normalizes Endoxifen Concentrations Without Increasing Toxicity.
Hertz, Daniel L⋅Deal, Allison⋅Ibrahim, Joseph G⋅Walko, Christine M⋅Weck, Karen E⋅Anderson, Steven⋅Magrinat, Gustav⋅Olajide, Oludamilola⋅Moore, Susan⋅Raab, Rachel⋅Carrizosa, Daniel R⋅Corso, Steven⋅Schwartz, Garry⋅Graham, Mark⋅Peppercorn, Jeffrey M⋅Jones, David R⋅Desta, Zeruesenay⋅Flockhart, David A⋅Evans, James P⋅Mc Leod, Howard L⋅Carey, Lisa A and Irvin, William J
The oncologist, vol. 21, (no. 7), pp. 795-803, July 2016. | Journal Article
 
Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer.
Lee, Jiyoon⋅Lee, Jiyoon⋅Lee, Jiyoon⋅Yakubov, Bakhtiyor⋅Yakubov, Bakhtiyor⋅Yakubov, Bakhtiyor⋅Ivan, Cristina⋅Ivan, Cristina⋅Ivan, Cristina⋅Jones, David⋅Jones, David⋅Jones, David R⋅Caperell-Grant, Andrea⋅Caperell-Grant, Andrea⋅Caperell-Grant, Andrea⋅Fishel, Melissa⋅Fishel, Melissa⋅Fishel, Melissa⋅Cardenas, Horacio⋅Cardenas, Horacio⋅Cardenas, Horacio⋅Matei, Daniela⋅Matei, Daniela and Matei, Daniela
Neoplasia (New York, N.Y.), vol. 18, (no. 11), pp. 689-698, October 25, 2016. | Journal Article
2015
In vivo assessment of the metabolic activity of CYP2D6 diplotypes and alleles.
Hertz, Daniel L⋅Snavely, Anna C⋅Mc Leod, Howard L⋅Walko, Christine M⋅Ibrahim, Joseph G⋅Anderson, Steven⋅Weck, Karen E⋅Magrinat, Gustav⋅Olajide, Oludamilola⋅Moore, Susan⋅Raab, Rachel⋅Carrizosa, Daniel R⋅Corso, Steven⋅Schwartz, Garry⋅Peppercorn, Jeffrey M⋅Evans, James P⋅Jones, David R⋅Desta, Zeruesenay⋅Flockhart, David A⋅Carey, Lisa A and Irvin, William J
British journal of clinical pharmacology, vol. 80, (no. 5), pp. 1122-1130, November 2015. | Journal Article
 
Nicotine and Cotinine Exposure from Electronic Cigarettes: A Population Approach
de Mendizábal, Nieves⋅Jones, David⋅Jahn, Andy⋅Bies, Robert and Brown, Joshua
Clinical Pharmacokinetics, vol. 54, (no. 6), pp. 615-626, Jun 2015. | Journal Article
 
Preclinical assessments of the MEK inhibitor PD-0325901 in a mouse model of Neurofibromatosis type 1.
Jousma, E.⋅Jousma, Edwin⋅Rizvi, T.A.⋅Rizvi, Tilat A⋅Wu, Jianqiang⋅Wu, J.⋅Janhofer, D.⋅Janhofer, David⋅Dombi, Eva⋅Dombi, E.⋅Dunn, Richard S⋅Dunn, R.S.⋅Kim, Mi-Ok⋅Kim, M. O.⋅Masters, A.R.⋅Masters, Andrea R⋅Jones, D.R.⋅Jones, David R⋅Cripe, Timothy P⋅Cripe, T.P.⋅Ratner, Nancy and Ratner, N.
Pediatric blood & cancer, vol. 62, (no. 10), pp. 1709-1716, October 2015. | Journal Article
2014
A phase II study of medroxyprogesterone acetate in patients with hormone receptor negative metastatic breast cancer: translational breast cancer research consortium trial 007
Miller, Kathy⋅Althouse, Sandra⋅Nabell, Lisle⋅Rugo, Hope⋅Carey, Lisa⋅Kimmick, Gretchen⋅Jones, David⋅Merino, Maria and Steeg, Patricia
Breast Cancer Research and Treatment, vol. 148, (no. 1), pp. 99-106, Nov 2014. | Journal Article
2013
Hemodialysis does not alter in vitro hepatic CYP3A4 and CYP2D6 metabolic activity in uremic serum.
Decker, Brian S⋅O'Neill, Kalisha D⋅Chambers, Mary A⋅Slaven, James E⋅Yu, Zhangsheng⋅Jones, David R and Moe, Sharon M
Clinical pharmacology : advances and applications, vol. 5, pp. 193-9, 2013. | Journal Article
 
In vivo DPP-4 inhibition to enhance engraftment of single-unit cord blood transplants in adults with hematological malignancies.
Farag, Sherif S⋅Srivastava, Shivani⋅Messina-Graham, Steven⋅Schwartz, Jennifer⋅Robertson, Michael J⋅Abonour, Rafat⋅Cornetta, Kenneth⋅Wood, Lisa⋅Secrest, Angie⋅Strother, R M⋅Jones, David R and Broxmeyer, Hal E
Stem cells and development, vol. 22, (no. 7), pp. 1007-15, 2013/Apr/1. | Journal Article
 
Pharmacokinetic and pharmacodynamic alterations in the Roux-en-Y gastric bypass recipients.
Tandra, Sweta⋅Chalasani, Naga P⋅Jones, David R⋅Mattar, Samer⋅Hall, Stephen D and Vuppalanchi, Raj
Annals of surgery, vol. 258, (no. 2), pp. 262-9, 2013/Aug. | Journal Article
 
Relationship between differential hepatic microRNA expression and decreased hepatic cytochrome P450 3A activity in cirrhosis.
Vuppalanchi, Raj⋅Vuppalanchi, Raj⋅Vuppalanchi, Raj⋅Vuppalanchi, Raj⋅Vuppalanchi, Raj⋅Vuppalanchi, Raj⋅Liang, Tiebing⋅Liang, Tiebing⋅Liang, Tiebing⋅Liang, Tiebing⋅Liang, Tiebing⋅Liang, Tiebing⋅Goswami, Chirayu P⋅Goswami, Chirayu Pankaj⋅Goswami, Chirayu Pankaj⋅Goswami, Chirayu Pankaj⋅Goswami, Chirayu Pankaj⋅Goswami, Chirayu P⋅Nalamasu, Rohit⋅Nalamasu, Rohit⋅Nalamasu, Rohit⋅Nalamasu, Rohit⋅Nalamasu, Rohit⋅Nalamasu, Rohit⋅Li, Lang⋅Li, Lang⋅Li, Lang⋅Lang, Li⋅Li, Lang⋅Li, Lang⋅Jones, David⋅Jones, David⋅Jones, David⋅Jones, David⋅Jones, David⋅Jones, David⋅Wei, Rongrong⋅Wei, Rongrong⋅Wei, Rongrong⋅Wei, Rongrong⋅Wei, Rongrong⋅Wei, Rongrong⋅Liu, Wanqing⋅Liu, Wanqing⋅Liu, Wanqing⋅Liu, Wanqing⋅Liu, Wanqing⋅Liu, Wanqing⋅Sarasani, Vishal⋅Sarasani, Vishal⋅Sarasani, Vishal⋅Sarasani, Vishal⋅Sarasani, Vishal⋅Sarasani, Vishal⋅Janga, Sarath C⋅Janga, Sarath Chandra⋅Janga, Sarath Chandra⋅Janga, Sarath Chandra⋅Janga, Sarath Chandra⋅Janga, Sarath C⋅Chalasani, Naga⋅Chalasani, Naga⋅Chalasani, Naga⋅Chalasani, Naga⋅Chalasani, Naga and Chalasani, Naga
PloS one, vol. 8, (no. 9), pp. e74471, 2013. | Journal Article
 
Use of dried plasma spots for the quantification of iothalamate in clinical studies.
Hagan, Andrew S⋅Jones, David R and Agarwal, Rajiv
Clinical journal of the American Society of Nephrology : CJASN, vol. 8, (no. 6), pp. 909-14, 2013/Jun. | Journal Article
2012
A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.
Zhang, Sheng⋅Liu, Sijiu⋅Tao, Rongya⋅Wei, Dan⋅Chen, Lan⋅Shen, Weihua⋅Yu, Zhi-Hong⋅Wang, Lina⋅Jones, David R⋅Dong, Xiaocheng C and Zhang, Z. F
Journal of the American Chemical Society, vol. 134, (no. 43), pp. 18116-24, 2012/Oct/31. | Journal Article
 
A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic.
Haas, David M⋅Quinney, Sara K⋅McCormick, Catherine L⋅Jones, David R and Renbarger, Jamie L
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 25, (no. 4), pp. 419-23, 2012/Apr. | Journal Article
 
Subcutaneous 5-Azacitidine Treatment of Naturally Occurring Canine Urothelial Carcinoma: A Novel Epigenetic Approach to Human Urothelial Carcinoma Drug Development
Hahn, Noah M⋅Hahn, Noah⋅Bonney, Patty L⋅Bonney, Patty⋅Dhawan, Deepika⋅Dhawan, Deepika⋅Jones, David R⋅Jones, David⋅Balch, Curtis⋅Balch, Curtis⋅Guo, Zhongmin⋅Guo, Zhongmin⋅Hartman-Frey, Corie⋅Hartman-Frey, Corie⋅Fang, Fang⋅Fang, Fang⋅Parker, Heidi G⋅Parker, Heidi⋅Kwon, Erika M⋅Kwon, Erika⋅Ostrander, Elaine A⋅Ostrander, Elaine⋅Nephew, Ken⋅Nephew, Kenneth⋅Knapp, Deborah and Knapp, Deborah W
Journal of Urology, vol. 187, (no. 1), pp. 302-309, 2012. | Journal Article
2011
A phase I trial of high-dose clofarabine, etoposide, and cyclophosphamide and autologous peripheral blood stem cell transplantation in patients with primary refractory and relapsed and refractory non-Hodgkin lymphoma.
Srivastava, Shivani⋅Jones, David⋅Wood, Lisa L⋅Schwartz, Jennifer⋅Nelson, Robert P⋅Abonour, Rafat⋅Secrest, Angie⋅Cox, Elizabeth⋅Baute, Jay⋅Sullivan, Cheryl⋅Kane, Kathleen⋅Robertson, Michael J and Farag, Sherif S
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, vol. 17, (no. 7), pp. 987-94, 2011/Jul. | Journal Article
 
Contribution of N-Glucuronidation to Efavirenz Elimination In Vivo in the Basal and Rifampin-Induced Metabolism of Efavirenz
Cho, Doo-Yeoun⋅Ogburn, Evan T⋅Jones, David R and Desta, Zeruesenay
Antimicrobial Agents & Chemotherapy, vol. 55, (no. 4), pp. 1504-1504, 2011. | Journal Article
 
Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity.
Cai, Shanbao⋅Cai, Shanbao⋅Wang, Haiyan⋅Wang, Haiyan⋅Bailey, Barbara⋅Bailey, Barbara⋅Ernstberger, Aaron⋅Ernstberger, Aaron⋅Juliar, Beth E⋅Juliar, Beth E⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Jones, David R⋅Jones, David R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Baluyut, Arthur R⋅Baluyut, Arthur R⋅Goebel, W S⋅Goebel, W Scott⋅Pollok, Karen E and Pollok, Karen E
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 17, (no. 8), pp. 2195-206, 2011/Apr/15. | Journal Article
 
Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growth.
Fishel, Melissa L⋅Fishel, Melissa L⋅Jiang, Yanlin⋅Jiang, Yanlin⋅Rajeshkumar, N V⋅Rajeshkumar, N V⋅Scandura, Glenda⋅Scandura, Glenda⋅Sinn, Anthony L⋅Sinn, Anthony L⋅He, Ying⋅He, Ying⋅Shen, Changyu⋅Shen, Changyu⋅Jones, David R⋅Jones, David R⋅Pollok, Karen E⋅Pollok, Karen E⋅Ivan, Mircea⋅Ivan, Mircea⋅Maitra, Anirban⋅Maitra, Anirban⋅Kelley, Mark R and Kelley, Mark
Molecular cancer therapeutics, vol. 10, (no. 9), pp. 1698-708, 2011/Sep. | Journal Article
 
Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis.
Wang, Fang⋅Wang, Fang⋅Li, Jing⋅Li, Jing⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Knabe, W. Eric⋅Knabe, W E⋅Khanna, May⋅Khanna, May⋅Jo, Inha⋅Jo, Inha⋅Silver, Jayne M⋅Silver, Jayne M⋅Oh, Kyungsoo⋅Oh, Kyungsoo⋅Li, Liwei⋅Li, Liwei⋅Sandusky, George E⋅Sandusky, George E⋅Sledge, George W⋅Sledge, George W⋅Nakshatri, Harikrishna⋅Nakshatri, Harikrishna⋅Jones, David R⋅Jones, David R⋅Pollok, Karen E⋅Pollok, Karen E⋅Meroueh, Samy O and Meroueh, Samy
Journal of medicinal chemistry, vol. 54, (no. 20), pp. 7193-205, 2011/Oct/27. | Journal Article