185 Publications (Page 5 of 8)
2011
Charge inversion at position 68 of the glucagon and glucagon-like peptide-1 receptors supports selectivity in hormone action
Day, Jonathan W⋅Day, Jonathan W⋅Day, Jonathan W⋅Li, Pengyun⋅Li, Pengyun⋅Li, Pengyun⋅Patterson, James T⋅Patterson, James T⋅Patterson, James T⋅Chabenne, Joe⋅Chabenne, Joe⋅Chabenne, Joe⋅Chabenne, Maria DiMarchi⋅Chabenne, Maria D⋅Chabenne, Maria DiMarchi⋅Gelfanov, Vasily M⋅Gelfanov, Vasily M⋅Gelfanov, Vasily M⋅DiMarchi, Richard D⋅DiMarchi, Richard D and Di Marchi, Richard D
Journal of Peptide Science, vol. 17, (no. 3), pp. 218-225, 2011. | Journal Article
 
Functional association of the N-terminal residues with the central region in glucagon-related peptides
Patterson, James T⋅Day, Jonathan W⋅Gelfanov, Vasily M and Di Marchi, Richard D
Journal of Peptide Science, vol. 17, (no. 10), pp. 659-666, 2011. | Journal Article
 
Ghrelin-induced hypothermia: A physiological basis but no clinical risk
Wiedmer, Petra⋅Strasser, Florian⋅Horvath, Tamas⋅Blum, David⋅Di Marchi, Richard D⋅Lutz, Thomas⋅Schuermann, Annette⋅Joost, Hans-Georg⋅Tschoep, Matthias and Tong, Jenny
Physiology & Behavior, vol. 105, (no. 1), pp. 43-51, 2011. | Journal Article
 
Optimized clinical performance of growth hormone with an expanded genetic code.
Cho, Ho⋅Daniel, Tom⋅Buechler, Ying J⋅Litzinger, David C⋅Maio, Zhenwei⋅Putnam, Anna-Maria H⋅Kraynov, Vadim S⋅Sim, Bee-Cheng⋅Bussell, Stuart⋅Javahishvili, Tsotne⋅Kaphle, Sami⋅Viramontes, Guillermo⋅Ong, Mike⋅Chu, Stephanie⋅Becky, G C⋅Lieu, Ricky⋅Knudsen, Nick⋅Castiglioni, Paola⋅Norman, Thea C⋅Axelrod, Douglas W⋅Hoffman, Andrew R⋅Schultz, Peter G⋅Di Marchi, Richard D and Kimmel, Bruce E
Proceedings of the National Academy of Sciences of the United States of America, vol. 108, (no. 22), pp. 9060-5, 2011/May/31. | Journal Article
2010
Combinatorial libraries of synthetic peptides as a model for shotgun proteomics.
Bohrer, Brian C⋅Li, Yong F⋅Reilly, James P⋅Clemmer, David E⋅Di Marchi, Richard D⋅Radivojac, Predrag⋅Tang, Haixu and Arnold, Randy J
Analytical chemistry, vol. 82, (no. 15), pp. 6559-68, 2010/Aug/1. | Journal Article
 
Glucagon regulation of energy metabolism
Heppner, Kristy⋅Heppner, Kristy M⋅Heppner, K.M.⋅Heppner, K.M.⋅Habegger, Kirk M⋅Habegger, Kirk⋅Habegger, K.M.⋅Habegger, K.M.⋅Day, Jonathan⋅Day, Jonathan⋅Day, J.⋅Day, J.⋅Pfluger, Paul⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Perez-Tilve, Diego⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅Ward, B.⋅Ward, Brian⋅Ward, B.⋅Ward, Brian⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Woods, S.C.⋅Woods, Steve⋅Woods, Stephen C⋅Woods, S.C.⋅DiMarchi, R.⋅DiMarchi, R.⋅DiMarchi, Richard⋅Di Marchi, Richard D⋅Tschöp, Matthias⋅Tschöp, M.⋅Tschoep, Matthias and Tschöp, M.
Physiology & Behavior, vol. 100, (no. 5), pp. 545-548, 2010. | Journal Article
 
In vitro and in vivo evaluation of native glucagon and glucagon analog (MAR-D28) during aging: lack of cytotoxicity and preservation of hyperglycemic effect.
Ward, W K⋅Massoud, Ryan G⋅Szybala, Cory J⋅Engle, Julia M⋅El Youssef, Joseph⋅Carroll, Julie M⋅Roberts, Charles T and Di Marchi, Richard D
Journal of diabetes science and technology, vol. 4, (no. 6), pp. 1311-21, 2010/Nov. | Journal Article
 
Melanocortin signaling in the CNS directly regulates circulating cholesterol.
Perez Tilve, Diego⋅Hofmann, Susanna⋅Basford, Joshua⋅Nogueiras, Rubén⋅Pfluger, Paul T⋅Patterson, James T⋅Grant, Erin⋅Wilson-Perez, Hilary E⋅Granholm, Norman A⋅Arnold, Myrtha⋅Trevaskis, James L⋅Butler, Andrew A⋅Davidson, William S⋅Woods, Stephen C⋅Benoit, Stephen C⋅Sleeman, Mark W⋅Di Marchi, Richard D⋅Hui, David and Tschoep, Matthias
Nature neuroscience, vol. 13, (no. 7), pp. 877-82, 2010/Jul. | Journal Article
 
Optimization of the native glucagon sequence for medicinal purposes.
Chabenne, Joseph R⋅DiMarchi, Maria A⋅Gelfanov, Vasily M and Di Marchi, Richard D
Journal of diabetes science and technology, vol. 4, (no. 6), pp. 1322-31, 2010/Nov. | Journal Article
 
Synthesis and characterization of ester-based prodrugs of glucagon-like peptide 1.
De, Arnab and Di Marchi, Richard D
Biopolymers, vol. 94, (no. 4), pp. 448-56, 2010. | Journal Article
 
The metabolic actions of glucagon revisited.
Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, Kirk M⋅Heppner, K.M.⋅Heppner, Kristy M⋅Heppner, Kristy M⋅Geary, N.⋅Geary, Nori⋅Geary, Nori⋅Bartness, Timothy J⋅Bartness, Timothy J⋅Bartness, T.J.⋅Di Marchi, Richard D⋅DiMarchi, R.⋅Dimarchi, Richard⋅Tschöp, Matthias H⋅Tschöp, M.H. and Tschoep, Matthias
Nature reviews. Endocrinology, vol. 6, (no. 12), pp. 689-97, 2010/Dec. | Journal Article
2009
A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
Lockie, Sarah Haas⋅Pfluger, Paul T⋅Ottaway, Nickki⋅Hembree, Jazzminn⋅DiMarchi, Richard⋅Day, Jonathan W⋅Chaudhary, Nilika⋅Abplanalp, William⋅Day, Jonathan⋅Perez-Tilve, Diego⋅Findeisen, Hannes⋅Nogueiras, Ruben⋅Bruemmer, Dennis⋅Woods, Stephen C⋅Drucker, Daniel J⋅Wilson, Hilary⋅Ruehl, Jennifer⋅Kirchner, Henriette⋅Patterson, James T⋅Tschöp, Matthias H⋅Holland, Jenna⋅Hofmann, Susanna⋅Gidda, Jas⋅Grant, Erin⋅Day, Jonathan W⋅Gelfanov, Vasily⋅Smiley, David⋅Ottaway, Nickki⋅Ottaway, Nickki⋅Patterson, James T⋅Patterson, James⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅Smiley, David⋅Smiley, David⋅Gidda, Jas⋅Gidda, Jas⋅Findeisen, Hannes⋅Findeisen, Hannes⋅Bruemmer, Dennis⋅Bruemmer, Dennis C⋅Drucker, Daniel J⋅Drucker, Daniel J⋅Chaudhary, Nilika⋅Chaudhary, Nilika⋅Holland, Jenna⋅Holland, Jenna⋅Hembree, Jazzminn⋅Hembree, Jazzminn⋅Abplanalp, William⋅Abplanalp, William⋅Grant, Erin⋅Grant, Erin⋅Ruehl, Jennifer⋅Ruehl, Jennifer⋅Wilson, Hilary⋅Wilson, Hilary⋅Kirchner, Henriette⋅Kirchner, Henriette⋅Lockie, Sarah H⋅Lockie, Sarah Kathleen Haas⋅Hofmann, Susanna⋅Hofmann, Susanna⋅Woods, Stephen C⋅Woods, Stephen C⋅Nogueiras, Rubén⋅Nogueiras, Ruben⋅Pfluger, Paul T⋅Pfluger, Paul T⋅Perez Tilve, Diego⋅Perez-Tilve, Diego⋅DiMarchi, Richard⋅Di Marchi, Richard D⋅Tschoep, Matthias and Tschop, Matthias H
Nature Chemical Biology, vol. 5, (no. 10), pp. 749-757, 2009. | Journal Article
 
Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity.
Nogueiras, Rubén⋅Perez Tilve, Diego⋅Veyrat-Durebex, Christelle⋅Morgan, Donald A⋅Varela, Luis⋅Haynes, William G⋅Patterson, James T⋅Disse, Emmanuel⋅Pfluger, Paul T⋅López, Miguel⋅Woods, Stephen C⋅Di Marchi, Richard D⋅Diéguez, Carlos⋅Rahmouni, Kamal⋅Jeanrenaud-Rohner, F. and Tschoep, Matthias
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 29, (no. 18), pp. 5916-25, 2009/May/6. | Journal Article
 
Ghrelin promotes and protects nigrostriatal dopamine function via a UCP2-dependent mitochondrial mechanism.
Andrews, Zane B⋅Andrews, Z.B.⋅Erion, D.⋅Erion, Derek⋅Beiler, R.⋅Beiler, Rudolph⋅Liu, Z.-W.⋅Liu, Zhong-Wu⋅Abizaid, Alfonso⋅Abizaid, A.⋅Zigman, Jeffrey⋅Zigman, J.⋅Elsworth, John D⋅Elsworth, J.D.⋅Savitt, J.M.⋅Savitt, Joseph M⋅Di Marchi, Richard⋅DiMarchi, R.⋅Tschoep, Matthias⋅Tschoep, M.⋅Roth, R.H.⋅Roth, Robert H⋅Gao, X.-B.⋅Gao, Xiao-Bing⋅Horvath, T.L. and Horvath, Tamas L
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 29, (no. 45), pp. 14057-65, 2009/Nov/11. | Journal Article
 
Side chain-to-side chain cyclization by intramolecular click reaction--building blocks, solid phase synthesis and conformational characterization.
Cantel, Sonia⋅Halperin, Jose A⋅Chorev, Michael⋅Scrima, Mario⋅D'Ursi, Anna M⋅Levy, Jay J⋅Di Marchi, Richard D⋅Le Chevalier, Alexandra⋅Rovero, Paolo and Papini, Anna Maria
Advances in experimental medicine and biology, vol. 611, pp. 175-6, 2009. | Journal Article
 
Side chain-to-side chain cyclization by intramolecular click reaction-building blocks, solid phase synthesis and conformational characterization
Cantel, Sonia⋅Halperin, Jose A⋅Chorev, Michael⋅Scrima, Mario⋅D'Ursi, Anna M⋅Levy, Jay J⋅Di Marchi, Richard D⋅Le Chevalier, Alexandra⋅Rovero, Paolo and Papini, Anna M
Advances in experimental medicine and biology, vol. 611, pp. 176, 2009-00-00. | Journal Article
 
Unnatural amino acid substitution as a probe of the allosteric coupling pathway in a mycobacterial Cu(I) sensor.
Ma, Zhen⋅Cowart, Darin M⋅Ward, Brian P⋅Arnold, Randy J⋅Di Marchi, Richard D⋅Zhang, Limei⋅George, Graham N⋅Scott, Robert A and Giedroc, David P
Journal of the American Chemical Society, vol. 131, (no. 50), pp. 18044-5, 2009/Dec/23. | Journal Article
2008
Crystallization and Preliminary X-Ray Analysis of Anti-Obesity Peptide Hormone Oxyntomodulin
Zhang, Faming⋅Zhang, Faming⋅Li, Pengyun⋅Li, Pengyun⋅Rogers, Tanya⋅Rogers, Tanya⋅Smiley, David⋅Smiley, David⋅DiMarchi, Richard⋅Di Marchi, Richard D and DiMarchi, Richard
Protein & Peptide Letters, vol. 15, (no. 2), pp. 232-234(3), 2008. | Journal Article
 
Investigation of the Feasibility of an Amide-based Prodrug Under Physiological Conditions
De, Arnab and Di Marchi, Richard
International Journal of Peptide Research and Therapeutics, vol. 14, (no. 4), pp. 393, 20081200. | Journal Article
 
Investigation of the Feasibily of an Amide-based Prodrug Under Physiological Conditions
De, Arnab and Di Marchi, Richard
International Journal of Peptide Research and Therapeutics, vol. 14, (no. 3), pp. 262, 20080900. | Journal Article
 
Synthesis and conformational analysis of a cyclic peptide obtained via i to i+4 intramolecular side-chain to side-chain azide-alkyne 1,3-dipolar cycloaddition.
Cantel, Sonia⋅Isaad, Alexandra L⋅Scrima, Mario⋅Levy, Jay J⋅Di Marchi, Richard D⋅Rovero, Paolo⋅Halperin, Jose A⋅D'Ursi, Anna M⋅Papini, Anna Maria and Chorev, Michael
The Journal of organic chemistry, vol. 73, (no. 15), pp. 5663-74, 2008/Aug/1. | Journal Article
2007
Design, synthesis and crystallization of a novel glucagon analog as a therapeutic agent.
Li, Pengyun⋅Li, Pengyun⋅Rogers, Tanya⋅Rogers, Tanya⋅Smiley, David⋅Smiley, David⋅Di Marchi, Richard D⋅DiMarchi, Richard D⋅Zhang, Faming and Zhang, Faming
Acta crystallographica. Section F, Structural biology and crystallization communications, vol. 63, (no. Pt 7), pp. 599-601, 2007/Jul/1. | Journal Article
 
Effects of Obestatin on Energy Balance and Growth Hormone Secretion in Rodents
Nogueiras, Rubén⋅Pfluger, Paul⋅Tovar, Sulay⋅Arnold, Myrtha⋅Mitchell, Sharon⋅Morris, Amanda⋅Perez Tilve, Diego⋅Vazquez, Maria J⋅Wiedmer, Petra⋅Castañeda, Tamara⋅Di Marchi, Richard D⋅Tschoep, Matthias⋅Schurmann, Annette⋅Joost, Hans-Georg⋅Williams, Lynda M⋅Langhans, Wolfgang and Dieguez, Carlos
Endocrinology, vol. 148, (no. 1), pp. 21-26, 2007. | Journal Article
 
Insulin structure and function
Mayer, John P⋅Zhang, Faming and Di Marchi, Richard D
Biopolymers, vol. 88, (no. 5), pp. 687-713, 2007. | Journal Article
 
pI-shifted insulin analogs with extended in vivo time action and favorable receptor selectivity.
Kohn, Wayne D⋅Micanovic, Radmila⋅Myers, Sharon L⋅Vick, Andrew M⋅Kahl, Steven D⋅Zhang, Lianshan⋅Strifler, Beth A⋅Li, Shun⋅Shang, Jing⋅Beals, John M⋅Mayer, John P and Di Marchi, Richard D
Peptides, vol. 28, (no. 4), pp. 935-48, 2007/Apr. | Journal Article