185 Publications (Page 4 of 8)
2014
A glucagon analog chemically stabilized for immediate treatment of life-threatening hypoglycemia.Chabenne, Joseph⋅Chabenne, Joseph⋅Chabenne, Maria⋅Chabenne, Maria D⋅Zhao, Yan⋅Zhao, Yan⋅Levy, Jay⋅Levy, Jay A⋅Smiley, David⋅Smiley, David⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅DiMarchi, Richard and Di Marchi, Richard DMolecular metabolism, vol. 3, (no. 3), pp. 293-300, 2014/Jun.
| Journal Article
Both acyl and des-acyl ghrelin regulate adiposity and glucose metabolism via central nervous system ghrelin receptors.Heppner, Kristy M⋅Heppner, K.M.⋅Heppner, K.M.⋅Heppner, Kristy M⋅Piechowski, C.L.⋅Piechowski, C.L.⋅Piechowski, Carolin L⋅Piechowski, Carolin L⋅Müller, A.⋅Müller, Anne⋅Müller, Anne⋅Müller, A.⋅Ottaway, N.⋅Ottaway, N.⋅Ottaway, Nickki⋅Ottaway, Nickki⋅Sisley, Stephanie⋅Sisley, Stephanie⋅Sisley, S.⋅Sisley, S.⋅Smiley, David L⋅Smiley, D.L.⋅Smiley, David L⋅Smiley, D.L.⋅Habegger, Kirk M⋅Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, K.M.⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Pfluger, Paul T⋅Di Marchi, Richard D⋅DiMarchi, R.⋅DiMarchi, R.⋅Dimarchi, Richard⋅Biebermann, Heike⋅Biebermann, H.⋅Biebermann, H.⋅Biebermann, Heike⋅Tschöp, M.H.⋅Tschöp, Matthias H⋅Tschoep, Matthias⋅Tschöp, M.H.⋅Sandoval, Darleen A⋅Sandoval, D.A.⋅Sandoval, Darleen A⋅Sandoval, D.A.⋅Perez-Tilve, D.⋅Perez-Tilve, D.⋅Perez-Tilve, Diego and Perez Tilve, DiegoDiabetes, vol. 63, (no. 1), pp. 122-31, 2014/Jan.
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Break on through to the other 1.Kharitonenkov, Alexei and Di Marchi, RichardCell metabolism, vol. 20, (no. 4), pp. 554-555, October 7, 2014.
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Chemical Synthesis of Insulin Analogs through a Novel Precursor.Zaykov, Alexander N⋅Zaykov, Alexander N⋅Mayer, John P⋅Mayer, John P⋅Gelfanov, Vasily M⋅Gelfanov, Vasily M⋅Di Marchi, Richard D and DiMarchi, Richard DACS chemical biology, vol. 9, (no. 3), pp. 683-91, 2014/Mar/21.
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Estrogens stimulate serotonin neurons to inhibit binge-like eating in miceCao, Xuehong⋅Cao, Xuehong⋅Xu, Pingwen⋅Xu, Pingwen⋅Oyola, Mario G⋅Oyola, Mario⋅Xia, Yan⋅Xia, Yan⋅Yan, Xiaofeng⋅Yan, Xiaofeng⋅Saito, Kenji⋅Saito, Kenji⋅Zou, Fang⋅Zou, Fang⋅Wang, Chunmei⋅Wang, Chunmei⋅Yang, Yongjie⋅Yang, Yongjie⋅Hinton, Antentor⋅Hinton, Antentor⋅Yan, Chunling⋅Yan, Chunling⋅Ding, Hongfang⋅Ding, Hongfang⋅Zhu, Liangru⋅Zhu, Liangru⋅Yu, Likai⋅Yu, Likai⋅Yang, Bin⋅Yang, Bin⋅Feng, Yuxin⋅Feng, Yuxin⋅Clegg, Deborah J⋅Clegg, Deborah⋅Khan, Sohaib⋅Khan, Sohaib⋅Di Marchi, Richard⋅DiMarchi, Richard⋅Mani, Shaila⋅Mani, Shaila K⋅Tong, Qingchun⋅Tong, Qingchun⋅Xu, Yong and Xu, YongJournal of Clinical Investigation, vol. 124, (no. 10), pp. 4351-62, Oct 2014.
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GLP-1/Glucagon Coagonism Restores Leptin Responsiveness in Obese Mice Chronically Maintained on an Obesogenic DietClemmensen, Christoffer⋅Clemmensen, Christoffer⋅Chabenne, Joseph⋅Chabenne, Joseph⋅Finan, Brian⋅Finan, Brian⋅Sullivan, Lorraine⋅Sullivan, Lorraine⋅Fischer, Katrin⋅Fischer, Katrin⋅Küchler, Daniela⋅Küchler, Daniela⋅Sehrer, Laura⋅Sehrer, Laura⋅Ograjsek, Teja⋅Ograjsek, Teja⋅Hofmann, Susanna M⋅Hofmann, Susanna⋅Schriever, Sonja C⋅Schriever, Sonja C⋅Pfluger, Paul T⋅Pfluger, Paul T⋅Pinkstaff, Jason⋅Pinkstaff, Jason⋅Tschoep, Matthias⋅Tschöp, Matthias H⋅Dimarchi, Richard⋅Dimarchi, Richard⋅Müller, Timo D and Müller, Timo DDiabetes, vol. 63, (no. 4), pp. 1427, 2014-Apr.
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GLP-1R responsiveness predicts individual gastric bypass efficacy on glucose tolerance in rats.Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, K.M.⋅Heppner, Kristy M⋅Heppner, K.M.⋅Heppner, K.M.⋅Amburgy, S.E.⋅Amburgy, Sarah E⋅Amburgy, S.E.⋅Ottaway, N.⋅Ottaway, N.⋅Ottaway, Nickki⋅Holland, Jenna⋅Holland, J.⋅Holland, J.⋅Raver, C.⋅Raver, Christine⋅Raver, C.⋅Bartley, Erin⋅Bartley, E.⋅Bartley, E.⋅Müller, Timo D⋅Müller, T.D.⋅Müller, T.D.⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Berger, Jose⋅Berger, J.⋅Berger, J.⋅Toure, M.⋅Toure, M.⋅Toure, Mouhamadoul⋅Benoit, S.C.⋅Benoit, Stephen C⋅Benoit, S.C.⋅Di Marchi, Richard D⋅DiMarchi, R.D.⋅DiMarchi, R.D.⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅D'alessio, David⋅D’Alessio, D.A.⋅D’Alessio, D.A.⋅Seeley, R.J.⋅Seeley, Randy J⋅Seeley, R.J.⋅Tschöp, M.H.⋅Tschoep, Matthias and Tschöp, M.H.Diabetes, vol. 63, (no. 2), pp. 505-13, 2014/Feb.
| Journal Article
2013
A hydrophobic site on the GLP-1 receptor extracellular domain orients the peptide ligand for signal transduction.Patterson, James⋅Patterson, James⋅Patterson, James T⋅Li, Pengyun⋅Li, Pengyun⋅Li, Pengyun⋅Day, Jonathan W⋅Day, Jonathan⋅Day, Jonathan⋅Gelfanov, Vasily M⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅Di Marchi, Richard D⋅DiMarchi, Richard and DiMarchi, RichardMolecular metabolism, vol. 2, (no. 2), pp. 86-91, 2013.
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Allosteric inhibition of a zinc-sensing transcriptional repressor: insights into the arsenic repressor (ArsR) family.Campanello, Gregory C⋅Ma, Zhen⋅Grossoehme, Nicholas E⋅Guerra, Alfredo J⋅Ward, Brian P⋅Di Marchi, Richard D⋅Ye, Yuzhen⋅Dann Iii, Charles E and Giedroc, David PJournal of molecular biology, vol. 425, (no. 7), pp. 1143-57, 2013/Apr/12.
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Discovery of high potency, single-chain insulin analogs with a shortened B-chain and nonpeptide linker.Kaur, Zachary P⋅Kaur, Zachary P⋅Ochman, Alexander R⋅Ochman, Alexander R⋅Mayer, John P⋅Mayer, John P⋅Gelfanov, Vasily M⋅Gelfanov, Vasily M⋅Di Marchi, Richard D and DiMarchi, Richard DACS chemical biology, vol. 8, (no. 8), pp. 1822-9, 2013/Aug/16.
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Fibroblast growth factor 21 mediates specific glucagon actions.Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, K.M.⋅Stemmer, K.⋅Stemmer, K.⋅Stemmer, Kerstin⋅Cheng, C.⋅Cheng, C.⋅Cheng, Christine⋅Müller, T.D.⋅Müller, T.D.⋅Müller, Timo D⋅Heppner, K.M.⋅Heppner, K.M.⋅Heppner, Kristy M⋅Ottaway, Nickki⋅Ottaway, N.⋅Ottaway, N.⋅Holland, J.⋅Holland, Jenna⋅Holland, J.⋅Hembree, J.L.⋅Hembree, Jazzminn L⋅Hembree, J.L.⋅Smiley, D.⋅Smiley, David⋅Smiley, D.⋅Gelfanov, V.⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Krishna, R.⋅Krishna, Radha⋅Krishna, R.⋅Arafat, A.M.⋅Arafat, Ayman M⋅Arafat, A.M.⋅Konkar, A.⋅Konkar, A.⋅Konkar, Anish⋅Belli, S.⋅Belli, S.⋅Belli, Sara⋅Kapps, M.⋅Kapps, M.⋅Kapps, Martin⋅Woods, Stephen C⋅Woods, S.C.⋅Woods, S.C.⋅Hofmann, Susanna⋅Hofmann, S.M.⋅Hofmann, S.M.⋅D’Alessio, D.⋅D'alessio, David⋅D’Alessio, D.⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅Seeley, Randy J⋅Seeley, R.J.⋅Seeley, R.J.⋅Konishi, M.⋅Konishi, Morichika⋅Konishi, M.⋅Itoh, N.⋅Itoh, N.⋅Itoh, Nobuyujki⋅Kharitonenkov, A.⋅Kharitonenkov, A.⋅Kharitonenkov, Alexei⋅Spranger, J.⋅Spranger, J.⋅Spranger, Joachim⋅Di Marchi, Richard D⋅DiMarchi, R.D.⋅DiMarchi, R.D.⋅Tschöp, M.H.⋅Tschoep, Matthias⋅Tschöp, M.H. and Tschöp, Matthias HDiabetes, vol. 62, (no. 5), pp. 1453-63, 2013/May.
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GLP-1R agonism enhances adjustable gastric banding in diet-induced obese rats.Habegger, K.M.⋅Habegger, K.M.⋅Habegger, Kirk M⋅Kirchner, H.⋅Kirchner, H.⋅Kirchner, Henriette⋅Yi, Chun-Xia⋅Yi, C.-X.⋅Yi, C.-X.⋅Heppner, K.M.⋅Heppner, Kristy M⋅Heppner, K.M.⋅Sweeney, D.⋅Sweeney, Dan⋅Sweeney, D.⋅Ottaway, N.⋅Ottaway, Nickki⋅Ottaway, N.⋅Holland, J.⋅Holland, J.⋅Holland, Jenna⋅Amburgy, S.⋅Amburgy, Sarah⋅Amburgy, S.⋅Raver, C.⋅Raver, C.⋅Raver, Christine⋅Krishna, Radhakrishna⋅Krishna, R.⋅Krishna, R.⋅Müller, Timo D⋅Müller, T.D.⋅Müller, T.D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅Perez-Tilve, D.⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Obici, S.⋅Obici, Silvana⋅Obici, S.⋅DiMarchi, R.D.⋅DiMarchi, R.D.⋅Di Marchi, Richard D⋅D'alessio, David⋅D’Alessio, D.A.⋅D’Alessio, D.A.⋅Seeley, R.J.⋅Seeley, R.J.⋅Seeley, Randy J⋅Tschöp, M.H.⋅Tschöp, M.H. and Tschoep, MatthiasDiabetes, vol. 62, (no. 9), pp. 3261-7, 2013/Sep.
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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic [Beta]-cellsKuna, Ramya S⋅Girada, Shravan B⋅Asalla, Suman⋅Vallentyne, Joyprashant⋅Maddika, Subbareddy⋅Patterson, James T⋅Smiley, David L⋅Di Marchi, Richard D and Mitra, PrasenjitAmerican Journal of Physiology, vol. 305, (no. 2), Jul 15, 2013.
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Glucagon-like peptide-1 receptor-mediated endosomal cAMP generation promotes glucose-stimulated insulin secretion in pancreatic β-cells.Kuna, Ramya S⋅Kuna, Ramya⋅Girada, Shravan B⋅Girada, Shravan⋅Asalla, Suman⋅Asalla, Suman⋅Vallentyne, Joyprashant⋅Vallentyne, Joyprashant⋅Maddika, Subbareddy⋅Maddika, Subbareddy⋅Patterson, James⋅Patterson, James T⋅Smiley, David⋅Smiley, David L⋅Di Marchi, Richard D⋅DiMarchi, Richard⋅Mitra, Prasenjit and Mitra, PrasenjitAmerican journal of physiology. Endocrinology and metabolism, vol. 305, (no. 2), pp. E161-70, 2013/Jul/15.
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Peptide lipidation stabilizes structure to enhance biological function.Ward, Brian P⋅Ottaway, Nickki L⋅Perez Tilve, Diego⋅Ma, Dejian⋅Gelfanov, Vasily M⋅Tschöp, Matthias H⋅Tschoep, Matthias⋅Di Marchi, Richard D and Dimarchi, Richard DMolecular metabolism, vol. 2, (no. 4), pp. 468-79, 2013.
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The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms.Müller, Timo D⋅Müller, T.D.⋅Müller, T.D.⋅Mul?ler, A.⋅Müller, Anne⋅Mul?ler, A.⋅Yi, C.-X.⋅Yi, C.-X.⋅Yi, Chun-Xia⋅Habegger, K.M.⋅Habegger, Kirk M⋅Habegger, K.M.⋅Meyer, C.W.⋅Meyer, Carola W⋅Meyer, C.W.⋅Gaylinn, B.D.⋅Gaylinn, Bruce D⋅Gaylinn, B.D.⋅Finan, B.⋅Finan, B.⋅Finan, Brian⋅Heppner, Kristy⋅Heppner, K.⋅Heppner, K.⋅Trivedi, C.⋅Trivedi, C.⋅Trivedi, Chitrang⋅Bielohuby, Maximilian⋅Bielohuby, M.⋅Bielohuby, M.⋅Abplanalp, W.⋅Abplanalp, W.⋅Abplanalp, William⋅Meyer, F.⋅Meyer, Franziska⋅Meyer, F.⋅Piechowski, C.L.⋅Piechowski, Carolin L⋅Piechowski, C.L.⋅Pratzka, Juliane⋅Pratzka, J.⋅Pratzka, J.⋅Stemmer, K.⋅Stemmer, Kerstin⋅Stemmer, K.⋅Holland, Jenna⋅Holland, J.⋅Holland, J.⋅Hembree, Jazzmin⋅Hembree, J.⋅Hembree, J.⋅Bhardwaj, N.⋅Bhardwaj, Nakul⋅Bhardwaj, N.⋅Raver, C.⋅Raver, Christine⋅Raver, C.⋅Ottaway, Nickki⋅Ottaway, N.⋅Ottaway, N.⋅Krishna, Radha⋅Krishna, R.⋅Krishna, R.⋅Sah, R.⋅Sah, R.⋅Sah, Renu⋅Sallee, F.R.⋅Sallee, Floyd R⋅Sallee, F.R.⋅Woods, Stephen C⋅Woods, S.C.⋅Woods, S.C.⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅Bidlingmaier, Martin⋅Bidlingmaier, M.⋅Bidlingmaier, M.⋅Thorner, M.O.⋅Thorner, Michael O⋅Thorner, M.O.⋅Krude, H.⋅Krude, Heiko⋅Krude, H.⋅Smiley, David⋅Smiley, D.⋅Smiley, D.⋅Di Marchi, Richard D⋅DiMarchi, R.⋅DiMarchi, R.⋅Hofmann, S.⋅Hofmann, S.⋅Hofmann, Susanna⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Kleinau, G.⋅Kleinau, Gunnar⋅Kleinau, G.⋅Biebermann, H.⋅Biebermann, H.⋅Biebermann, Heike⋅Tschoep, Matthias⋅Tsc?op, M.H. and Tsc?op, M.H.Nature communications, vol. 4, pp. 1968, 2013.
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Unimolecular dual incretins maximize metabolic benefits in rodents, monkeys, and humans.Finan, B.⋅Finan, Brian⋅Finan, Brian⋅Finan, B.⋅Finan, Brian⋅Ma, T.⋅Ma, Tao⋅Ma, Tao⋅Ma, T.⋅Ma, Tao⋅Ottaway, N.⋅Ottaway, Nickki⋅Ottaway, N.⋅Ottaway, Nickki⋅Ottaway, Nickki⋅Müller, Timo D⋅Müller, T.D.⋅Müller, T.D.⋅Muller, Timo D⋅Müller, Timo D⋅Habegger, Kirk M⋅Habegger, Kirk⋅Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, K.M.⋅Heppner, K.M.⋅Heppner, Kristy M⋅Heppner, Kristy⋅Heppner, Kristy M⋅Heppner, K.M.⋅Kirchner, Henriette⋅Kirchner, H.⋅Kirchner, H.⋅Kirchner, Henriette⋅Kirchner, Henriette⋅Holland, J.⋅Holland, J.⋅Holland, Jenna⋅Holland, Jenna⋅Holland, Jenna⋅Hembree, J.⋅Hembree, Jazzminn⋅Hembree, J.⋅Hembree, Jazzminn⋅Hembree, Jazzminn⋅Raver, Christine⋅Raver, C.⋅Raver, Christine⋅Raver, Christine⋅Raver, C.⋅Lockie, Sarah H⋅Lockie, Sarah Kathleen Haas⋅Lockie, S.H.⋅Lockie, S.H.⋅Lockie, Sarah H⋅Smiley, David L⋅Smiley, David⋅Smiley, D.L.⋅Smiley, D.L.⋅Smiley, David L⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Yang, B.⋅Yang, Bin⋅Yang, Bin⋅Yang, B.⋅Yang, Bin⋅Hofmann, Susanna⋅Hofmann, Susanna⋅Hofmann, S.⋅Hofmann, S.⋅Hofmann, Susanna⋅Bruemmer, D.⋅Bruemmer, Dennis⋅Bruemmer, Dennis C⋅Bruemmer, Dennis⋅Bruemmer, D.⋅Drucker, D.J.⋅Drucker, Daniel J⋅Drucker, Daniel J⋅Drucker, Daniel J⋅Drucker, D.J.⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Pfluger, Paul T⋅Perez-Tilve, Diego⋅Perez-Tilve, D.⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, Diego⋅Gidda, Jaswant⋅Gidda, J.⋅Gidda, Jaswant⋅Gidda, Jas⋅Gidda, J.⋅Vignati, Louis⋅Vignati, Louis⋅Vignati, Louis⋅Vignati, L.⋅Vignati, L.⋅Zhang, Lianshan⋅Zhang, L.⋅Zhang, Lianshan⋅Zhang, L.⋅Zhang, Lianshan⋅Hauptman, J.B.⋅Hauptman, Jonathan B⋅Hauptman, J.B.⋅Hauptman, Jonathan B⋅Hauptman, Jonathan B⋅Lau, M.⋅Lau, M.⋅Lau, Michele⋅Lau, Michele⋅Lau, Michele⋅Brecheisen, Mathieu⋅Brecheisen, M.⋅Brecheisen, M.⋅Brecheisen, Mathieu⋅Brecheisen, Mathieu⋅Uhles, S.⋅Uhles, Sabine⋅Uhles, Sabine⋅Uhles, S.⋅Uhles, Sabine⋅Riboulet, William⋅Riboulet, William⋅Riboulet, W.⋅Riboulet, William⋅Riboulet, W.⋅Hainaut, Emmanuelle⋅Hainaut, E.⋅Hainaut, Emmanuelle⋅Hainaut, Emmanuelle⋅Hainaut, E.⋅Sebokova, Elena⋅Sebokova, Elena⋅Sebokova, E.⋅Sebokova, E.⋅Sebokova, Elena⋅Conde-Knape, Karin⋅Conde-Knape, K.⋅Conde-Knape, Karin⋅Conde-Knape, Karin⋅Conde-Knape, K.⋅Konkar, Anish⋅Konkar, A.⋅Konkar, Anish⋅Konkar, Anish⋅Konkar, A.⋅DiMarchi, R.D.⋅DiMarchi, Richard⋅Di Marchi, Richard D⋅DiMarchi, Richard D⋅DiMarchi, R.D.⋅Tschöp, Matthias H⋅Tschop, Matthias H⋅Tschoep, Matthias⋅Tschöp, M.H.⋅Tschöp, M.H. and Tschöp, Matthias HScience translational medicine, vol. 5, (no. 209), pp. 209ra151, 2013/Oct/30.
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2012
Acylation type determines ghrelin's effects on energy homeostasis in rodents.Heppner, Kristy M⋅Heppner, K.M.⋅Heppner, K.M.⋅Heppner, Kristy M⋅Chaudhary, N.⋅Chaudhary, N.⋅Chaudhary, Nilika⋅Chaudhary, Nilika⋅Müller, T.D.⋅Müller, T.D.⋅Müller, Timo D⋅Müller, Timo D⋅Kirchner, Henriette⋅Kirchner, Henriette⋅Kirchner, H.⋅Kirchner, H.⋅Habegger, Kirk M⋅Habegger, K.M.⋅Habegger, Kirk M⋅Habegger, K.M.⋅Ottaway, Nickki⋅Ottaway, N.⋅Ottaway, Nickki⋅Ottaway, N.⋅Smiley, David L⋅Smiley, D.L.⋅Smiley, David L⋅Smiley, D.L.⋅Di Marchi, Richard D⋅DiMarchi, Richard⋅DiMarchi, R.⋅DiMarchi, R.⋅Hofmann, Susanna⋅Hofmann, S.M.⋅Hofmann, S.M.⋅Hofmann, Susanna M⋅Woods, S.C.⋅Woods, Stephen C⋅Woods, Stephen C⋅Woods, S.C.⋅Sivertsen, B.⋅Sivertsen, B.⋅Sivertsen, Bjørn⋅Sivertsen, Bjørn B⋅Holst, B.⋅Holst, B.⋅Holst, Birgitte⋅Holst, Birgitte⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Perez-Tilve, Diego⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Perez-Tilve, D.⋅Tschöp, M.H.⋅Tschöp, M.H.⋅Tschöp, Matthias H and Tschoep, MatthiasEndocrinology, vol. 153, (no. 10), pp. 4687-95, 2012/Oct.
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Direct control of brown adipose tissue thermogenesis by central nervous system glucagon-like peptide-1 receptor signaling.Lockie, Sarah Kathleen Haas⋅Lockie, S.H.⋅Lockie, Sarah H⋅Heppner, Kristy M⋅Heppner, K.M.⋅Heppner, Kristy M⋅Chaudhary, Nilika⋅Chaudhary, N.⋅Chaudhary, Nilika⋅Chabenne, J.R.⋅Chabenne, Joseph R⋅Chabenne, Joseph R⋅Morgan, D.A.⋅Morgan, Donald A⋅Morgan, Donald A⋅Veyrat-Durebex, C.⋅Veyrat-Durebex, Christelle⋅Veyrat-Durebex, Christelle⋅Ananthakrishnan, G.⋅Ananthakrishnan, Gayathri⋅Ananthakrishnan, Gayathri⋅Rohner-Jeanrenaud, Francoise⋅Rohner-Jeanrenaud, F.⋅Jeanrenaud-Rohner, F.⋅Drucker, Daniel J⋅Drucker, D.J.⋅Drucker, Daniel J⋅DiMarchi, Richard⋅Di Marchi, Richard D⋅DiMarchi, R.⋅Rahmouni, Kamal⋅Rahmouni, K.⋅Rahmouni, Kamal⋅Oldfield, Brian J⋅Oldfield, B.J.⋅Oldfield, Brian J⋅Tschöp, M.H.⋅Tschoep, Matthias⋅Tschop, Matthias H⋅Perez-Tilve, Diego⋅Perez Tilve, Diego and Perez-Tilve, D.Diabetes, vol. 61, (no. 11), pp. 2753-62, 2012/Nov.
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FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in RodentsMu, James⋅Pinkstaff, Jason⋅Li, Zhihua⋅Skidmore, Lillian⋅Li, Nina⋅Myler, Heather⋅Dallas-Yang, Qing⋅Putnam, Anna-Maria⋅Yao, Jun⋅Bussell, Stuart⋅Wu, Margaret⋅Norman, Thea C⋅Rodriguez, Carlos G⋅Kimmel, Bruce⋅Metzger, Joseph M⋅Manibusan, Anthony⋅Lee, Darin⋅Zaller, Dennis M⋅Zhang, Bei B⋅Di Marchi, Richard D⋅Berger, Joel P and Axelrod, Douglas WDiabetes, vol. 61, (no. 2), pp. 505-12, Feb 2012.
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Optimization of co-agonism at GLP-1 and glucagon receptors to safely maximize weight reduction in DIO-rodents.Day, Jonathan W⋅Day, Jonathan W⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅Smiley, David⋅Smiley, David⋅Carrington, Paul E⋅Carrington, Paul E⋅Eiermann, George⋅Eiermann, George⋅Chicchi, Gary⋅Chicchi, Gary⋅Erion, Mark D⋅Erion, Mark D⋅Gidda, Jas⋅Gidda, Jas⋅Thornberry, Nancy A⋅Thornberry, Nancy A⋅Tschoep, Matthias⋅Tschöp, Matthias H⋅Marsh, Donald J⋅Marsh, Donald J⋅Sinharoy, Ranabir⋅SinhaRoy, Ranabir⋅DiMarchi, Richard⋅Di Marchi, Richard D⋅Pocai, Alessandro and Pocai, AlessandroBiopolymers, vol. 98, (no. 5), pp. 443-50, 2012.
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Outstanding Scientific Achievement Award Lecture 2011: defeating diabesity: the case for personalized combinatorial therapies.Tschoep, Matthias and Di Marchi, Richard DDiabetes, vol. 61, (no. 6), pp. 1309-14, 2012/Jun.
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Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21.Müller, T.D.⋅Müller, Timo D⋅Müller, T.D.⋅Sullivan, L.M.⋅Sullivan, Lorraine M⋅Sullivan, L.M.⋅Habegger, K.⋅Habegger, Kirk⋅Habegger, K.⋅Yi, C.-X.⋅Yi, Chun-Xia⋅Yi, C.-X.⋅Kabra, Dhiraj⋅Kabra, D.⋅Kabra, D.⋅Grant, E.⋅Grant, E.⋅Grant, Erin⋅Ottaway, Nickki⋅Ottaway, N.⋅Ottaway, N.⋅Krishna, Radha⋅Krishna, R.⋅Krishna, R.⋅Holland, Jenna⋅Holland, J.⋅Holland, J.⋅Hembree, Jazzminn⋅Hembree, J.⋅Hembree, J.⋅Perez-Tilve, D.⋅Perez-Tilve, D.⋅Perez Tilve, Diego⋅Pfluger, P.T.⋅Pfluger, Paul T⋅Pfluger, P.T.⋅Deguzman, M.J.⋅Deguzman, M.J.⋅Deguzman, Michael J⋅Siladi, M.E.⋅Siladi, M.E.⋅Siladi, Marc E⋅Kraynov, Vadim S⋅Kraynov, V.S.⋅Kraynov, V.S.⋅Axelrod, Douglas W⋅Axelrod, D.W.⋅Axelrod, D.W.⋅Di Marchi, Richard D⋅Dimarchi, R.⋅Dimarchi, R.⋅Pinkstaff, J.K.⋅Pinkstaff, Jason K⋅Pinkstaff, J.K.⋅Tschöp, M.H.⋅Tschoep, Matthias and Tschöp, M.H.Journal of peptide science : an official publication of the European Peptide Society, vol. 18, (no. 6), pp. 383-93, 2012/Jun.
| Journal Article
Targeted estrogen delivery reverses the metabolic syndromeFinan, Brian⋅Finan, Brian⋅Finan, B.⋅Yang, B.⋅Yang, Bin⋅Yang, Bin⋅Ottaway, Nickki⋅Ottaway, Nickki⋅Ottaway, N.⋅Stemmer, Kerstin⋅Stemmer, K.⋅Stemmer, Kerstin⋅Müller, T.D.⋅Müller, Timo D⋅Müller, Timo D⋅Yi, Chun-xia⋅Yi, Chun-xia⋅Yi, C.-X.⋅Habegger, K.⋅Habegger, Kirk⋅Habegger, Kirk⋅Schriever, Sonja C⋅Schriever, S.C.⋅Schriever, Sonja C⋅García-cáceres, Cristina⋅García-Cáceres, C.⋅García-cáceres, Cristina⋅Kabra, Dhiraj G⋅Kabra, Dhiraj G⋅Kabra, D.G.⋅Hembree, Jazzminn⋅Hembree, Jazzminn⋅Hembree, J.⋅Holland, Jenna⋅Holland, Jenna⋅Holland, J.⋅Raver, C.⋅Raver, Christine⋅Raver, Christine⋅Seeley, Randy J⋅Seeley, Randy J⋅Seeley, R.J.⋅Hans, W.⋅Hans, Wolfgang⋅Hans, Wolfgang⋅Irmler, M.⋅Irmler, Martin⋅Irmler, Martin⋅Beckers, Johannes⋅Beckers, J.⋅Beckers, Johannes⋅De Angelis, Martin H⋅De Angelis, M.H.⋅De Angelis, Martin H⋅Tiano, Joseph P⋅Tiano, Joseph P⋅Tiano, J.P.⋅Mauvais-jarvis, Franck⋅Mauvais-jarvis, Franck⋅Mauvais-Jarvis, F.⋅Perez Tilve, Diego⋅Perez-tilve, Diego⋅Perez-Tilve, D.⋅Pfluger, Paul⋅Pfluger, P.⋅Pfluger, Paul⋅Zhang, Lianshan⋅Zhang, L.⋅Zhang, Lianshan⋅Gelfanov, Vasily⋅Gelfanov, Vasily⋅Gelfanov, V.⋅Dimarchi, R.D.⋅Di Marchi, Richard D⋅Dimarchi, Richard D⋅Tschöp, Matthias H⋅Tschoep, Matthias and Tschöp, M.H.Nature Medicine, vol. 18, (no. 12), pp. 1847-56, Dec 2012.
| Journal Article
2011
A novel human-based receptor antagonist of sustained action reveals body weight control by endogenous GLP-1.Patterson, James T⋅Patterson, James T⋅Ottaway, Nickki⋅Ottaway, Nickki⋅Gelfanov, Vasily M⋅Gelfanov, Vasily M⋅Smiley, David L⋅Smiley, David L⋅Perez Tilve, Diego⋅Perez-Tilve, Diego⋅Pfluger, Paul T⋅Pfluger, Paul T⋅Tschöp, Matthias H⋅Tschöp, Matthias H⋅Tschoep, Matthias⋅Dimarchi, Richard D⋅Di Marchi, Richard D and DiMarchi, Richard DACS chemical biology, vol. 6, (no. 2), pp. 135-45, 2011/Feb/18.
| Journal Article