185 Publications (Page 2 of 8)
Deletion of the glucagon receptor gene before and after experimental diabetes reveals differential protection from hyperglycemia
Rivero-Gutierrez, B.Rivero-Gutierrez, B.B, Rivero-GutierrezRivero-Gutierrez, BelenRivero-Gutierrez, BelenHaller, AprilA, HallerHaller, A.Haller, A.Haller, AprilHolland, JennaHolland, JennaJ, HollandHolland, J.Holland, J.Yates, E.Yates, E.Yates, EmilyE, YatesYates, EmilyKhrisna, RadhaR, KhrisnaKhrisna, R.Khrisna, RadhaKhrisna, R.K, HabeggerHabegger, KirkHabegger, KirkHabegger, K.Habegger, K.Dimarchi, RichardR, DimarchiDimarchi, R.Dimarchi, RichardDimarchi, R.D'Alessio, DavidD’Alessio, D.D'Alessio, DavidD, D’AlessioD’Alessio, D.Perez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, D.Perez-Tilve, D. and D, Perez-Tilve
Molecular Metabolism, vol. 17, pp. 38, November 2018. | Journal Article
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases.
Clemmensen, ChristofferFinan, BrianMüller, Timo DDi Marchi, Richard DTschöp, Matthias H and Hofmann, Susanna M
Nature reviews. Endocrinology, November 16, 2018. | Journal Article
Glucagon Receptor Signaling Regulates Energy Metabolism via Hepatic Farnesoid X Receptor and Fibroblast Growth Factor 21
Kim, T.Kim, TeayounKim, T.Kim, TeayounKim, TeayounKim, TeayounKim, T.Nason, S.Nason, ShellyNason, S.Nason, S.Nason, ShellyNason, ShellyNason, ShellyHolleman, CassieHolleman, C.Holleman, CassieHolleman, CassieHolleman, C.Holleman, C.Holleman, CassiePepin, M.Pepin, M.Pepin, MarkPepin, MarkPepin, M.Pepin, MarkPepin, MarkWilson, L.Wilson, L.Wilson, LandonWilson, LandonWilson, L.Wilson, LandonWilson, LandonBerryhill, Taylor FBerryhill, Taylor FBerryhill, T.F.Berryhill, Taylor FBerryhill, T.F.Berryhill, Taylor FBerryhill, T.F.Wende, Adam RWende, Adam RWende, A.R.Wende, Adam RWende, A.R.Wende, A.R.Wende, Adam RSteele, ChadSteele, ChadSteele, ChadSteele, ChadSteele, C.Steele, C.Steele, C.Young, Martin EYoung, Martin EYoung, Martin EYoung, Martin EYoung, M.E.Young, M.E.Young, M.E.Barnes, S.Barnes, StephenBarnes, S.Barnes, StephenBarnes, StephenBarnes, S.Barnes, StephenDrucker, D.J.Drucker, Daniel JDrucker, D.J.Drucker, Daniel JDrucker, Daniel JDrucker, D.J.Drucker, Daniel JFinan, BrianFinan, B.Finan, BrianFinan, B.Finan, BrianFinan, BrianFinan, B.DiMarchi, RichardDiMarchi, RichardDiMarchi, RichardDiMarchi, R.DiMarchi, R.DiMarchi, R.Di Marchi, RichardPerez-Tilve, D.Perez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, D.Perez-Tilve, D.Perez-Tilve, DiegoPerez-Tilve, DiegoTschöp, MatthiasTschöp, MatthiasTschöp, MatthiasTschöp, M.Tschoep, MatthiasTschöp, M.Tschöp, M.Habegger, K.M.Habegger, K.M.Habegger, Kirk MHabegger, Kirk MHabegger, Kirk MHabegger, K.M. and Habegger, Kirk M
Diabetes, vol. 67, (no. 9), pp. 1782, 2018-09-00. | Journal Article
Glucagon-Receptor Signaling Regulates Mitochondrial Bioenergetics via Hepatic Farnesol X Receptor
Diabetes, vol. 67, (no. Supplement 1), pp. 1978, 2018-05-00. | Journal Article
Glucagon Regulates Energy Balance via FGF-21 Signaling in the Brain
Diabetes, vol. 67, (no. Supplement 1), pp. 1806, 2018-05-00. | Journal Article
Hepatic Glucagon Receptor Signaling Enhances Insulin-Stimulated Glucose Disposal in Rodents
Kim, TeayounKim, T.Kim, T.Kim, TeayounKim, TeayounHolleman, Cassie LHolleman, Cassie LHolleman, C.L.Holleman, Cassie LHolleman, C.L.Nason, ShellyNason, ShellyNason, S.Nason, ShellyNason, S.Arble, Deanna MArble, Deanna MArble, D.M.Arble, D.M.Arble, Deanna MOttaway, NickkiOttaway, NickkiOttaway, NickkiOttaway, N.Ottaway, N.Chabenne, JosephChabenne, JosephChabenne, JosephChabenne, J.Chabenne, J.Loyd, ChristineLoyd, C.Loyd, ChristineLoyd, C.Loyd, ChristineKim, Jeong-AKim, J.-A.Kim, Jeong-AKim, J.-A.Kim, Jeong-ASandoval, DarleenSandoval, DarleenSandoval, D.Sandoval, DarleenSandoval, D.Drucker, D.J.Drucker, Daniel JDrucker, Daniel JDrucker, Daniel JDrucker, D.J.DiMarchi, R.DiMarchi, RichardDi Marchi, RichardDiMarchi, R.DiMarchi, RichardPerez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, D.Perez-Tilve, D.Habegger, Kirk MHabegger, Kirk MHabegger, K.M.Habegger, Kirk M and Habegger, K.M.
Diabetes, vol. 67, (no. 11), pp. 2166, 2018-11-00. | Journal Article
High-Yield Synthesis of Human Insulin-Like Peptide 5 Employing a Nonconventional Strategy.
Zaykov, Alexander NZaykov, Alexander NGelfanov, Vasily MGelfanov, Vasily MLiu, FaLiu, FaDiMarchi, Richard D and Di Marchi, Richard D
Organic letters, vol. 20, (no. 12), pp. 3695-3699, June 15, 2018. | Journal Article
"Let's Stay Together"; GIP and GLP-1 dual agonism in the treatment of metabolic disease.
Di Marchi, Richard D
Molecular metabolism, October 12, 2018. | Journal Article
Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs
Renner, SimoneBlutke, AndreasDobenecker, BrittaDhom, GeorgMüller, Timo DFinan, BrianClemmensen, ChristofferBernau, MarenNovak, IstvanRathkolb, BirgitSenf, SteffanieZöls, SusanneRoth, MirjamGötz, AnnaHofmann, Susanna MHrabĕ de Angelis, MartinWanke, RüdigerKienzle, EllenScholz, Armin MDi Marchi, RichardRitzmann, MathiasTschöp, Matthias H and Wolf, Eckhard
Molecular Metabolism, vol. 16, pp. 190, October 2018. | Journal Article
Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
Agrawal, ArchitaAgrawal, ArchitaAgrawal, ArchitaParlee, SebastianParlee, SebastianParlee, SebastianParlee, SebastianPerez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, DiegoPerez-Tilve, DiegoLi, PengyunLi, PengyunLi, PengyunLi, PengyunPan, JiaPan, JiaPan, JiaPan, JiaMroz, Piotr AMroz, Piotr AMroz, Piotr AMroz, Piotr AKruse Hansen, Ann MariaKruse Hansen, Ann MariaKruse Hansen, Ann MariaKruse Hansen, Ann MAndersen, BirgitteAndersen, BirgitteAndersen, BirgitteAndersen, BirgitteFinan, BrianFinan, BrianFinan, BrianFinan, BrianKharitonenkov, AlexeiKharitonenkov, AlexeiKharitonenkov, AlexeiKharitonenkov, AlexeiDi Marchi, Richard DDiMarchi, Richard DDiMarchi, Richard D and DiMarchi, Richard D
Molecular Metabolism, vol. 13, pp. 55, July 2018. | Journal Article
Optimized GIP analogs promote body weight lowering in mice through GIPR agonism not antagonism.
Mroz, Piotr AMroz, Piotr AMroz, Piotr AFinan, BrianFinan, BrianFinan, BrianGelfanov, VasilyGelfanov, VasilyGelfanov, VasilyYang, BinYang, BinYang, BinTschöp, Matthias HTschöp, Matthias HTschöp, Matthias HDi Marchi, Richard DDiMarchi, Richard DDiMarchi, Richard DPerez-Tilve, DiegoPerez-Tilve, Diego and Perez-Tilve, Diego
Molecular metabolism, December 5, 2018. | Journal Article
Structurally Constrained Insulin Analogs by Directed Stepwise Crosslinking
Zhang, FaZhang, FaZhang, FaMayer, JohnMayer, JohnMayer, JohnGelfanov, VasilyGelfanov, VasilyGelfanov, VasilyLiu, FaLiu, FaLiu, FaDiMarchi, RichardDiMarchi, Richard and Di Marchi, Richard
Protein & Peptide Letters, vol. 25, (no. 12), pp. 1154, 20180000. | Journal Article
Synthesis and Characterization of the R27S Genetic Variant of Insulin‐like Peptide 5
Zaykov, Alexander NZaykov, Alexander NGelfanov, Vasily MGelfanov, Vasily MLiu, FaLiu, FaDiMarchi, Richard D and Di Marchi, Richard D
ChemMedChem, vol. 13, (no. 8), pp. 859, April 23, 2018. | Journal Article
Synthesis of disulfide-rich heterodimeric peptides through an auxiliary N, N-crosslink
Thalluri, KishoreThalluri, KishoreThalluri, KishoreMayer, John PMayer, John PMayer, John PChabenne, Joseph RChabenne, Joseph RChabenne, Joseph RGelfanov, VasilyGelfanov, VasilyGelfanov, VasilyDiMarchi, Richard DDi Marchi, Richard D and DiMarchi, Richard D
Communications Chemistry, vol. 1, (no. 1), pp. 7, 2018-12-00. | Journal Article
Targeting the Incretin/Glucagon System with Triagonists to Treat Diabetes.
Capozzi, Megan EDi Marchi, Richard DTschöp, Matthias HFinan, Brian and Campbell, Jonathan E
Endocrine reviews, June 13, 2018. | Journal Article
Targeting the Incretin/Glucagon System With Triagonists to Treat Diabetes
Capozzi, Megan ECapozzi, Megan EDi Marchi, Richard DDiMarchi, Richard DTschöp, Matthias HTschöp, Matthias HFinan, BrianFinan, BrianCampbell, Jonathan E and Campbell, Jonathan E
Endocrine Reviews, vol. 39, (no. 5), pp. 738, 2018-October. | Journal Article
Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions
Altindis, EmrahAltindis, EmrahAltindis, EmrahCai, WeikangCai, WeikangCai, WeikangSakaguchi, MasajiSakaguchi, MasajiSakaguchi, MasajiZhang, FaZhang, FaZhang, FaGuoXiao, WangGuoXiao, WangGuoXiao, WangLiu, FaLiu, FaLiu, FaDe Meyts, PierreDe Meyts, PierreMey, PierreGelfanov, VasilyGelfanov, VasilyPan, HuiPan, HuiDi Marchi, RichardDiMarchi, RichardKahn, C Ronald and Kahn, C Ronald
Proceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 10), pp. 2466, 2018-03-06. | Journal Article
Biomimetic Synthesis of Insulin Enabled by Oxime Ligation and Traceless “C-Peptide” Chemical Excision
Thalluri, KishoreThalluri, KishoreThalluri, KishoreThalluri, KishoreKou, BinbinKou, BinbinKou, BinbinKou, BinbinGelfanov, VasilyGelfanov, VasilyGelfanov, VasilyGelfanov, VasilyMayer, John PMayer, John PMayer, John PMayer, John PLiu, FaLiu, FaLiu, FaLiu, FaDiMarchi, Richard DDiMarchi, Richard DDiMarchi, Richard D and Di Marchi, Richard D
Organic Letters, vol. 19, (no. 3), pp. 709, 2017-02-03. | Journal Article
Emerging Poly-Agonists for Obesity and Type 2 Diabetes
Kleinert, MaximilianClemmensen, ChristofferStemmer, KerstinMüller, Timo DDi Marchi, Richard D and Tschöp, Matthias H
Obesity, vol. 25, (no. 10), pp. 1649, 2017-10-00. | Journal Article
GLP-1 based multi-agonists-induced signaling includes profound TRP channel involvement in insulin secretion
Khajavi, NoushafarinFinan, BrianKluth, OliverMergler, StefanMuller, TimoKleinau, GunnarSchurmann, AnnetteTschop, Matthias HDi Marchi, RichardKrude, Heiko and Biebermann, Heike
Endocrine Abstracts, 2017-05-03. | Journal Article
GLP-1/glucagon receptor co-agonism for treatment of obesity.
Sánchez-Garrido, Miguel ABrandt, Sara JClemmensen, ChristofferMüller, Timo DDi Marchi, Richard D and Tschöp, Matthias H
Diabetologia, July 21, 2017. | Journal Article
Gαs regulates Glucagon-Like Peptide 1 Receptor-mediated cyclic AMP generation at Rab5 endosomal compartment
Girada, Shravan BabuKuna, Ramya SBele, ShilpakZhu, ZhimengChakravarthi, N.RDi Marchi, Richard D and Mitra, Prasenjit
Molecular Metabolism, vol. 6, (no. 10), pp. 1185, October 2017. | Journal Article
Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity
Quarta, CarmeloQuarta, C.Quarta, CarmeloClemmensen, C.Clemmensen, ChristofferClemmensen, ChristofferZhu, ZhimengZhu, Z.Zhu, ZhimengYang, BinYang, B.Yang, BinJoseph, Sini SJoseph, S.S.Joseph, Sini SLutter, DominikLutter, D.Lutter, DominikYi, Chun-XiaYi, C.-X.Yi, Chun-XiaGraf, E.Graf, ElisabethGraf, ElisabethGarcía-Cáceres, CristinaGarcía-Cáceres, CristinaGarcía-Cáceres, C.Legutko, BeataLegutko, BeataLegutko, B.Fischer, KatrinFischer, KatrinFischer, K.Brommage, RobertBrommage, RobertBrommage, R.Zizzari, PhilippeZizzari, P.Zizzari, PhilippeFranklin, B.S.Franklin, Bernardo SFranklin, Bernardo SKrueger, M.Krueger, MartinKrueger, MartinKoch, MarcoKoch, MarcoKoch, M.Vettorazzi, SabineVettorazzi, SabineVettorazzi, S.Li, PengyunLi, PengyunLi, P.Hofmann, Susanna MHofmann, Susanna MHofmann, S.M.Bakhti, MostafaBakhti, MostafaBakhti, M.Bastidas-Ponce, AiméeBastidas-Ponce, AiméeBastidas-Ponce, A.Lickert, HeikoLickert, H.Lickert, HeikoStrom, Tim MStrom, Tim MStrom, T.M.Gailus-Durner, V.Gailus-Durner, ValerieGailus-Durner, ValerieBechmann, IngoBechmann, IngoBechmann, I.Perez-Tilve, D.Perez-Tilve, DiegoPerez-Tilve, DiegoTuckermann, JanTuckermann, J.Tuckermann, JanHrabě de Angelis, MartinHrabě de Angelis, MartinAngelis, M.Sandoval, D.Sandoval, DarleenSandoval, DarleenCota, DanielaCota, DanielaCota, D.Latz, EickeLatz, EickeLatz, E.Seeley, Randy JSeeley, Randy JSeeley, R.J.Müller, Timo DMüller, Timo DMüller, T.D.DiMarchi, R.D.DiMarchi, Richard DDi Marchi, Richard DFinan, BrianFinan, BrianFinan, B.Tschöp, M.H.Tschöp, Matthias H and Tschöp, Matthias H
Cell Metabolism, vol. 26, (no. 4), pp. 632.e6, 2017-10-03. | Journal Article
Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice
Jall, SigridSachs, StephanClemmensen, ChristofferFinan, BrianNeff, FraukeDi Marchi, RichardTschöp, MatthiasMüller, Timo and Hofmann, Susanna
Molecular Metabolism, vol. 6, (no. 5), pp. 446, 2017. | Journal Article
Novel GLP-1R/GIPR co-agonist “twincretin” is neuroprotective in cell and rodent models of mild traumatic brain injury
Tamargo, Ian ABader, MiaadLi, YazhouYu, Seong-JinWang, YunTalbot, KonradDi Marchi, Richard DPick, Chaim G and Greig, Nigel H
Experimental Neurology, vol. 288, pp. 186, February 2017. | Journal Article