131 Publications (Page 2 of 6)
2017
Control of Bone Anabolism in Response to Mechanical Loading and PTH by Distinct Mechanisms Downstream of the PTH Receptor
Delgado‐Calle, Jesus⋅Delgado-Calle, Jesus⋅Delgado Calle, Jesus⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Pacheco‐Costa, Rafael⋅Pacheco-Costa, Rafael⋅Pacheco-Costa, Rafael⋅McAndrews, Kevin⋅McAndrews, Kevin⋅McAndrews, Kevin⋅Edwards, Rachel⋅Edwards, Rachel⋅Edwards, Rachel⋅Pellegrini, Gretel G⋅Pellegrini, Gretel G⋅Pellegrini, Gretel G⋅Kuhlenschmidt, Kali⋅Kuhlenschmidt, Kali⋅Kuhlenschmidt, Kali⋅Olivos, Naomie⋅Olivos, Naomie⋅Olivos, Naomie⋅Robling, Alexander⋅Robling, Alexander⋅Robling, Alexander⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Bellido, Teresita⋅Bellido, Teresita and Bellido, Teresita
Journal of Bone and Mineral Research, vol. 32, (no. 3), pp. 535, March 2017. | Journal Article
 
Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism
Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Davis, Hannah⋅Davis, Hannah⋅Davis, Hannah⋅Davis, Hannah⋅Davis, Hannah⋅Davis, Hannah⋅Davis, Hannah⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅Plotkin, Lilian I⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅Condon, Keith W⋅Condon, Keith W⋅Condon, Keith W⋅Condon, Keith W⋅Condon, Keith W⋅Condon, Keith W⋅Condon, Keith W⋅Burr, David B⋅Burr, David B⋅Burr, David B⋅Burr, David B⋅Burr, David B⋅Burr, David B⋅Burr, David B⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Wek, Ronald C⋅Wek, Ronald C⋅Wek, Ronald C⋅Wek, Ronald C⋅Wek, Ronald C⋅Wek, Ronald C⋅Wek, Ronald C⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P and Bidwell, Joseph P
Endocrinology, vol. 158, (no. 9), pp. 2740, 2017-09-01. | Journal Article
 
Old age causes de novo intracortical bone remodeling and porosity in mice
Piemontese, Marilina⋅Almeida, Maria⋅Robling, Alexander G⋅Kim, Ha-Neui⋅Xiong, Jinhu⋅Thostenson, Jeff D⋅Weinstein, Robert S⋅Manolagas, Stavros C⋅O'Brien, Charles A and Jilka, Robert L
JCI insight, vol. 2, (no. 17), 2017-09-07. | Journal Article
 
Quick and inexpensive paraffin-embedding method for dynamic bone formation analyses
Porter, Amy⋅Irwin, Regina⋅Miller, Josselyn⋅Horan, Daniel J⋅Robling, Alexander G and McCabe, Laura R
Scientific reports, vol. 7, (no. 1), pp. 42505, 2017-02-15. | Journal Article
 
Sclerostin: from bedside to bench, and back to bedside
Robling, Alexander⋅Drake, Matthew and Papapoulos, Socrates
Bone, vol. 96, pp. 2, 2017. | Journal Article
 
WNT-Mediated Modulation of Bone Metabolism: Implications for WNT Targeting to Treat Extra-Skeletal Disorders
Bullock, Whitney A and Robling, Alexander G
Toxicologic pathology, vol. 45, (no. 7), pp. 868, 2017-10-01. | Journal Article
2016
Adult-Onset Deletion of β-Catenin in (10kb)Dmp1-Expressing Cells Prevents Intermittent PTH-Induced Bone Gain.
Kedlaya, Rajendra⋅Kang, Kyung Shin⋅Hong, Jung Min⋅Bettagere, Vidya⋅Lim, Kyung-Eun⋅Horan, Daniel⋅Divieti-Pajevic, Paola and Robling, Alexander G
Endocrinology, vol. 157, (no. 8), pp. 3047-3057, August 2016. | Journal Article
 
Bone Matrix Composition Following PTH Treatment is Not Dependent on Sclerostin Status
Ross, Ryan⋅Ross, Ryan⋅Ross, Ryan D⋅Mashiatulla, Maleeha⋅Mashiatulla, Maleeha⋅Mashiatulla, Maleeha⋅Robling, Alexander G⋅Robling, Alexander⋅Robling, Alexander⋅Miller, Lisa⋅Miller, Lisa⋅Miller, Lisa M⋅Sumner, D. Rick⋅Sumner, D Rick and Sumner, D. Rick
Calcified Tissue International, vol. 98, (no. 2), pp. 157, 20160200. | Journal Article
 
Differential Bone Loss in Mouse Models of Colon Cancer Cachexia
Bonetto, Andrea⋅Bonetto, Andrea⋅Bonetto, Andrea⋅Bonetto, Andrea⋅Bonetto, Andrea⋅Bonetto, Andrea⋅Kays, Joshua K⋅Kays, Joshua K⋅Kays, Joshua K⋅Kays, Joshua K⋅Kays, Joshua K⋅Kays, Joshua K⋅Parker, Valorie A⋅Parker, Valorie A⋅Parker, Valorie A⋅Parker, Valorie A⋅Parker, Valorie A⋅Parker, Valorie A⋅Matthews, Ryan R⋅Matthews, Ryan R⋅Matthews, Ryan R⋅Matthews, Ryan R⋅Matthews, Ryan R⋅Matthews, Ryan R⋅Barreto, Rafael⋅Barreto, Rafael⋅Barreto, Rafael⋅Barreto, Rafael⋅Barreto, Rafael⋅Barreto, Rafael⋅Puppa, Melissa J⋅Puppa, Melissa J⋅Puppa, Melissa J⋅Puppa, Melissa J⋅Puppa, Melissa J⋅Puppa, Melissa J⋅Kang, Kyung S⋅Kang, Kyung S⋅Kang, Kyung S⋅Kang, Kyung S⋅Kang, Kyung S⋅Kang, Kyung S⋅Carson, James A⋅Carson, James A⋅Carson, James A⋅Carson, James A⋅Carson, James A⋅Carson, James A⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Guise, Theresa A⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Mohammad, Khalid S⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Couch, Marion E⋅Couch, Marion E⋅Couch, Marion E⋅Couch, Marion E⋅Couch, Marion E⋅Couch, Marion E⋅Koniaris, Leonidas G⋅Koniaris, Leonidas G⋅Koniaris, Leonidas G⋅Koniaris, Leonidas G⋅Koniaris, Leonidas G⋅Koniaris, Leonidas G⋅Zimmers, Teresa A⋅Zimmers, Teresa A⋅Zimmers, Teresa A⋅Zimmers, Teresa A⋅Zimmers, Teresa A and Zimmers, Teresa A
Frontiers in physiology, vol. 7, pp. 679, 2016-00-00. | Journal Article
 
Enhanced Wnt signaling improves bone mass and strength, but not brittleness, in the Col1a1(+/mov13) mouse model of type I Osteogenesis Imperfecta.
Jacobsen, Christina M⋅Schwartz, Marissa A⋅Roberts, Heather J⋅Lim, Kyung-Eun⋅Spevak, Lyudmila⋅Boskey, Adele L⋅Zurakowski, David⋅Robling, Alexander G and Warman, Matthew L
Bone, vol. 90, pp. 127-132, September 2016. | Journal Article
 
Osteoblast-Specific Overexpression of Human WNT16 Increases Both Cortical and Trabecular Bone Mass and Structure in Mice.
Alam, Imranul⋅Alkhouli, Mohammed⋅Gerard-O'Riley, Rita L⋅Wright, Weston B⋅Acton, Dena⋅Gray, Amie K⋅Patel, Bhavmik⋅Reilly, Austin M⋅Lim, Kyung-Eun⋅Robling, Alexander G and Econs, Michael J
Endocrinology, vol. 157, (no. 2), pp. 722-736, February 2016. | Journal Article
 
Postnatal β-catenin deletion from Dmp1-expressing osteocytes/osteoblasts reduces structural adaptation to loading, but not periosteal load-induced bone formation.
Kang, Kyung Shin⋅Hong, Jung Min and Robling, Alexander G
Bone, vol. 88, pp. 138-145, July 2016. | Journal Article
 
Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.
Collette, Nicole M⋅Yee, Cristal S⋅Hum, Nicholas R⋅Murugesh, Deepa K⋅Christiansen, Blaine A⋅Xie, LiQin⋅Economides, Aris N⋅Manilay, Jennifer O⋅Robling, Alexander G and Loots, Gabriela G
Bone, vol. 88, pp. 20-30, July 2016. | Journal Article
 
Sost, independent of the non-coding enhancer ECR5, is required for bone mechanoadaptation.
Robling, Alexander G⋅Kang, Kyung Shin⋅Bullock, Whitney A⋅Foster, William H⋅Murugesh, Deepa⋅Loots, Gabriela G and Genetos, Damian C
Bone, vol. 92, pp. 180-188, November 2016. | Journal Article
2015
Bone and skeletal muscle: Key players in mechanotransduction and potential overlapping mechanisms
Goodman, Craig⋅Goodman, C.A.⋅Hornberger, Troy⋅Hornberger, T.A.⋅Robling, Alexander and Robling, A.G.
Bone, vol. 80, pp. 36, 2015. | Journal Article
 
Genome-Wide Mapping and Interrogation of the Nmp4 Antianabolic Bone Axis
Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Stayrook, Keith R⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Alvarez, Marta B⋅Wang, Zhiping⋅Wang, Zhiping⋅Wang, Zhiping⋅Wang, Zhiping⋅Wang, Zhiping⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Shao, Yu⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Hernandez-Buquer, Selene⋅Mack, Justin K⋅Mack, Justin K⋅Mack, Justin K⋅Mack, Justin K⋅Mack, Justin K⋅Grese, Zachary R⋅Grese, Zachary R⋅Grese, Zachary R⋅Grese, Zachary R⋅Grese, Zachary R⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅He, Yongzheng⋅Horan, Daniel⋅Horan, Daniel⋅Horan, Daniel⋅Horan, Daniel⋅Horan, Daniel⋅Pavalko, Fredrick M⋅Pavalko, Fredrick M⋅Pavalko, Fredrick M⋅Pavalko, Fredrick M⋅Pavalko, Fredrick M⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Warden, Stuart J⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Yang, Feng Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Allen, Matthew R⋅Krishnan, Venkatesh⋅Krishnan, Venkatesh⋅Krishnan, Venkatesh⋅Krishnan, Venkatesh⋅Krishnan, Venkatesh⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P⋅Bidwell, Joseph P and Bidwell, Joseph P
Molecular Endocrinology, vol. 29, (no. 9), pp. 1285, 2015-9. | Journal Article
 
High Bone Mass–Causing Mutant LRP5 Receptors Are Resistant to Endogenous Inhibitors In Vivo
Niziolek, Paul J⋅Niziolek, Paul J⋅Niziolek, Paul J⋅MacDonald, Bryan T⋅MacDonald, Bryan T⋅MacDonald, Bryan T⋅Kedlaya, Rajendra⋅Kedlaya, Rajendra⋅Kedlaya, Rajendra⋅Zhang, Minjie⋅Zhang, Minjie⋅Zhang, Minjie⋅Bellido, Teresita⋅Bellido, Teresita⋅Bellido, Teresita⋅He, Xi⋅He, Xi⋅He, Xi⋅Warman, Matthew L⋅Warman, Matthew L⋅Warman, Matthew L⋅Robling, Alexander G⋅Robling, Alexander G and Robling, Alexander G
Journal of Bone and Mineral Research, vol. 30, (no. 10), pp. 1830, October 2015. | Journal Article
 
In vivo axial loading of the mouse tibia
Melville, Katherine M⋅Melville, Katherine M⋅Robling, Alexander G⋅Robling, Alexander G⋅Van Der Meulen, Marjolein C H and van der Meulen, Marjolein C H
Methods in molecular biology (Clifton, N.J.), vol. 1226, pp. 115, 2015-00-00. | Journal Article
 
Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia
Niziolek, Paul J⋅Niziolek, Paul J⋅Niziolek, Paul⋅Bullock, Whitney⋅Bullock, Whitney⋅Bullock, Whitney⋅Warman, Matthew⋅Warman, Matthew L⋅Warman, Matthew L⋅Robling, Alexander G⋅Robling, Alexander G and Robling, Alexander
PLoS ONE, vol. 10, (no. 11), pp. e0140775, 2015-11-10. | Journal Article
2014
Mechanosignaling in Bone Health, Trauma and Inflammation
Knapik, Derrick M⋅Knapik, Derrick M⋅Knapik, Derrick M⋅Perera, Priyangi⋅Perera, Priyangi⋅Perera, Priyangi⋅Nam, Jin⋅Nam, Jin⋅Nam, Jin⋅Blazek, Alisa D⋅Blazek, Alisa D⋅Blazek, Alisa D⋅Rath, Björn⋅Rath, Björn⋅Rath, Björn⋅Leblebicioglu, Binnaz⋅Leblebicioglu, Binnaz⋅Leblebicioglu, Binnaz⋅Das, Hiranmoy⋅Das, Hiranmoy⋅Das, Hiranmoy⋅Wu, Lai Chu⋅Wu, Lai C⋅Wu, Lai Chu⋅Hewett, Timothy E⋅Hewett, Timothy E⋅Hewett, Timothy E⋅Agarwal, Suresh⋅Agarwal, Suresh K⋅Agarwal, Suresh K⋅Robling, Alexander G⋅Robling, Alexander G⋅Robling, Alexander G⋅Flanigan, David C⋅Flanigan, David C⋅Flanigan, David C⋅Lee, Beth S⋅Lee, Beth S⋅Lee, Beth S⋅Agarwal, Sudha⋅Agarwal, Sudha and Agarwal, Sudha
Antioxidants & Redox Signaling, vol. 20, (no. 6), pp. 985, 2014-02-20. | Journal Article
 
New Insights into Wnt-Lrp5/6-β-Catenin Signaling in Mechanotransduction
Kang, Kyung Shin and Robling, Alexander G
Frontiers in endocrinology, vol. 5, pp. 246, 2014-00-00. | Journal Article
 
Reply to Lrp5 regulation of bone mass and gut serotonin synthesis
Cui, Yajun⋅Cui, Yajun⋅Cui, Yajun⋅Niziolek, Paul J⋅Niziolek, Paul J⋅Niziolek, Paul J⋅Macdonald, Bryan T⋅MacDonald, Bryan T⋅MacDonald, Bryan T⋅Alenina, Natalia⋅Alenina, Natalia⋅Alenina, Natalia⋅Matthes, Susann⋅Matthes, Susann⋅Matthes, Susann⋅Jacobsen, Christina M⋅Jacobsen, Christina M⋅Jacobsen, Christina M⋅Conlon, Ronald A⋅Conlon, Ronald A⋅Conlon, Ronald A⋅Brommage, Robert⋅Brommage, Robert⋅Brommage, Robert⋅Powell, David R⋅Powell, David R⋅Powell, David R⋅He, Xi⋅He, Xi⋅He, Xi⋅Bader, Michael⋅Bader, Michael⋅Bader, Michael⋅Williams, Bart O⋅Williams, Bart O⋅Williams, Bart O⋅Warman, Matthew L⋅Warman, Matthew L⋅Warman, Matthew L⋅Robling, Alexander G⋅Robling, Alexander G and Robling, Alexander G
Nature medicine, vol. 20, (no. 11), pp. 1230, 2014-Nov. | Journal Article
 
Targeting the LRP5 Pathway Improves Bone Properties in a Mouse Model of Osteogenesis Imperfecta
Jacobsen, Christina M⋅Jacobsen, Christina M⋅Barber, Lauren A⋅Barber, Lauren A⋅Ayturk, Ugur M⋅Ayturk, Ugur M⋅Roberts, Heather J⋅Roberts, Heather J⋅Deal, Lauren E⋅Deal, Lauren E⋅Schwartz, Marissa A⋅Schwartz, Marissa A⋅Weis, MaryAnn⋅Weis, MaryAnn⋅Eyre, David⋅Eyre, David⋅Zurakowski, David⋅Zurakowski, David⋅Robling, Alexander G⋅Robling, Alexander G⋅Warman, Matthew L and Warman, Matthew L
Journal of Bone and Mineral Research, vol. 29, (no. 10), pp. 2306, October 2014. | Journal Article
2013
Absence of Cx43 selectively from osteocytes enhances responsiveness to mechanical force in mice.
Bivi, Nicoletta⋅Pacheco-Costa, Rafael⋅Brun, Lucas R⋅Murphy, Thomas R⋅Farlow, Nathan R⋅Robling, Alexander⋅Bellido, Teresita and Plotkin, Lilian I
Journal of orthopaedic research : official publication of the Orthopaedic Research Society, vol. 31, (no. 7), pp. 1075-81, 2013/Jul. | Journal Article
 
An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutations.
Ayturk, Ugur M⋅Jacobsen, Christina M⋅Christodoulou, Danos C⋅Gorham, Joshua⋅Seidman, Jonathan G⋅Seidman, Kricket⋅Robling, Alexander and Warman, Matthew L
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, vol. 28, (no. 10), pp. 2081-93, 2013/Oct. | Journal Article