131 Publications (Page 1 of 6)
2021
Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice
Donham, CristineDonham, CristineChicana, BetsabelChicana, BetsabelRobling, Alexander GRobling, Alexander GMohamed, AsmaaMohamed, AsmaaElizaldi, SonnyElizaldi, SonnyChi, MichaelChi, MichaelFreeman, BrianFreeman, BrianMillan, AlbertoMillan, AlbertoMurugesh, Deepa KMurugesh, Deepa KHum, Nicholas RHum, Nicholas RLoots, Gabriela GLoots, Gabriela GManilay, Jennifer O and Manilay, Jennifer O
International Journal of Molecular Sciences, vol. 22, (no. 17), 2021. | Journal Article
2020
An osteocalcin-deficient mouse strain without endocrine abnormalities
Diegel, Cassandra RDiegel, Cassandra RDiegel, Cassandra RHann, StevenHann, StevenHann, StevenAyturk, Ugur MAyturk, Ugur MAyturk, Ugur MHu, Jennifer CHu, Jennifer CHu, Jennifer CLim, Kyung-eunLim, Kyung-eunLim, Kyung-eunDroscha, Casey JDroscha, Casey JDroscha, Casey JMadaj, Zachary BMadaj, Zachary BMadaj, Zachary BFoxa, Gabrielle EFoxa, Gabrielle EFoxa, Gabrielle EIzaguirre, IsaacIzaguirre, IsaacIzaguirre, IsaacParacha, NoorulainParacha, NoorulainParacha, NoorulainPidhaynyy, BohdanPidhaynyy, BohdanPidhaynyy, BohdanDowd, Terry LDowd, Terry LDowd, Terry LRobling, Alexander GRobling, Alexander GRobling, Alexander GWarman, Matthew LWarman, Matthew LWarman, Matthew LWilliams, Bart OWilliams, Bart O and Williams, Bart O
PLoS Genetics, vol. 16, (no. 5), May 2020. | Journal Article
 
Combination therapy in the Col1a2 G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone
Kaupp, ShannonHoran, Dan JLim, Kyung-EunFeldman, Henry ARobling, Alexander GWarman, Matthew L and Jacobsen, Christina M
Bone, vol. 131, pp. 115084, 2020-Feb. | Journal Article
 
Combination therapy in the Col1a2G610C mouse model of Osteogenesis Imperfecta reveals an additive effect of enhancing LRP5 signaling and inhibiting TGFβ signaling on trabecular bone but not on cortical bone
Kaupp, ShannonHoran, Dan JLim, Kyung-EunFeldman, Henry ARobling, Alexander GWarman, Matthew L and Jacobsen, Christina M
Bone, vol. 131, pp. 115084, February 2020. | Journal Article
 
Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion
Fan, YaoFan, YaoFan, YaoFan, YaoJalali, AydinJalali, AydinJalali, AydinJalali, AydinChen, AndyChen, AndyChen, AndyChen, AndyZhao, XinyuZhao, XinyuZhao, XinyuZhao, XinyuLiu, ShengzhiLiu, ShengzhiLiu, ShengzhiLiu, ShengzhiTeli, MeghanaTeli, MeghanaTeli, MeghanaTeli, MeghanaGuo, YunxiaGuo, YunxiaGuo, YunxiaGuo, YunxiaLi, FangjiaLi, FangjiaLi, FangjiaLi, FangjiaLi, JunruiLi, JunruiLi, JunruiLi, JunruiSiegel, AmandaSiegel, AmandaSiegel, AmandaSiegel, AmandaYang, LianxiangYang, LianxiangYang, LianxiangYang, LianxiangLiu, JingLiu, JingLiu, JingLiu, JingNa, SungsooNa, SungsooNa, SungsooNa, SungsooAgarwal, MangilalAgarwal, MangilalAgarwal, MangilalAgarwal, MangilalRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GNakshatri, HarikrishnaNakshatri, HarikrishnaNakshatri, HarikrishnaNakshatri, HarikrishnaLi, Bai-YanLi, Bai-YanLi, Bai-YanLi, Bai-YanYokota, HirokiYokota, HirokiYokota, Hiroki and Yokota, Hiroki
Bone research, vol. 8, (no. 1), pp. 9, 2020-00-00. | Journal Article
 
The mTORC2 component Rictor is required for load‐induced bone formation in late‐stage skeletal cells
Lewis, Karl JYi, XinWright, Christian SPemberton, Emily ZBullock, Whitney AThompson, William R and Robling, Alexander G
JBMR Plus, 2020-04-17. | Journal Article
 
The Osteocyte: New Insights
Robling, Alexander G and Bonewald, Lynda F
Annual Review of Physiology, vol. 82, (no. 1), pp. 506, 20200210. | Journal Article
 
YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling
Kegelman, Christopher DKegelman, Christopher DCoulombe, Jennifer CCoulombe, Jennifer CJordan, Kelsey MJordan, Kelsey MHoran, Daniel JHoran, Daniel JQin, LingQin, LingRobling, Alexander GRobling, Alexander GFerguson, Virginia LFerguson, Virginia LBellido, Teresita MBellido, Teresita MBoerckel, Joel D and Boerckel, Joel D
Journal of Bone and Mineral Research, vol. 35, (no. 1), pp. 210, January 2020. | Journal Article
2019
Differential changes in bone strength of two inbred mouse strains following administration of a sclerostin-neutralizing antibody during growth
Mathis, Noah JMathis, Noah JAdaniya, Emily NAdaniya, Emily NSmith, Lauren MSmith, Lauren MRobling, Alexander GRobling, Alexander GJepsen, Karl JJepsen, Karl JSchlecht, Stephen H and Schlecht, Stephen H
PloS one, vol. 14, (no. 4), pp. e0214520, 2019-00-00. | Journal Article
 
Expression of a Degradation‐Resistant β‐Catenin Mutant in Osteocytes Protects the Skeleton From Mechanodeprivation‐Induced Bone Wasting
Bullock, Whitney ABullock, Whitney ABullock, Whitney AHoggatt, April MHoggatt, April MHoggatt, April MHoran, Daniel JHoran, Daniel JHoran, Daniel JLewis, Karl JLewis, Karl JLewis, Karl JYokota, HirokiYokota, HirokiYokota, HirokiHann, StevenHann, StevenHann, StevenWarman, Matthew LWarman, Matthew LWarman, Matthew LSebastian, AimySebastian, AimySebastian, AimyLoots, Gabriela GLoots, Gabriela GLoots, Gabriela GPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MRobling, Alexander GRobling, Alexander G and Robling, Alexander G
Journal of Bone and Mineral Research, vol. 34, (no. 10), pp. 1975, October 2019. | Journal Article
 
Loss of Nmp4 optimizes osteogenic metabolism and secretion to enhance bone quality
Shao, YuShao, YuShao, YuShao, YuShao, YuShao, YuShao, YuShao, YuWichern, EmilyWichern, EmilyWichern, EmilyWichern, EmilyWichern, EmilyWichern, EmilyWichern, EmilyWichern, EmilyChildress, Paul JChildress, Paul JChildress, Paul JChildress, Paul JChildress, Paul JChildress, Paul JChildress, Paul JChildress, Paul JAdaway, MicheleAdaway, MicheleAdaway, MicheleAdaway, MicheleAdaway, MicheleAdaway, MicheleAdaway, MicheleAdaway, MicheleMisra, JagannathMisra, JagannathMisra, JagannathMisra, JagannathMisra, JagannathMisra, JagannathMisra, JagannathMisra, JagannathKlunk, AngelaKlunk, AngelaKlunk, AngelaKlunk, AngelaKlunk, AngelaKlunk, AngelaKlunk, AngelaKlunk, AngelaBurr, David BBurr, David BBurr, David BBurr, David BBurr, David BBurr, David BBurr, David BBurr, David BWek, Ronald CWek, Ronald CWek, Ronald CWek, Ronald CWek, Ronald CWek, Ronald CWek, Ronald CWek, Ronald CMosley, Amber LMosley, Amber LMosley, Amber LMosley, Amber LMosley, Amber LMosley, Amber LMosley, Amber LMosley, Amber LLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayBrustovetsky, NickolayHamilton, JamesHamilton, JamesHamilton, JamesHamilton, JamesHamilton, JamesHamilton, JamesHamilton, JamesHamilton, JamesJacobs, KylieJacobs, KylieJacobs, KylieJacobs, KylieJacobs, KylieJacobs, KylieJacobs, KylieJacobs, KylieVashishth, DeepakVashishth, DeepakVashishth, DeepakVashishth, DeepakVashishth, DeepakVashishth, DeepakVashishth, DeepakVashishth, DeepakStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RWallace, Joseph MWallace, Joseph MWallace, Joseph MWallace, Joseph MWallace, Joseph MWallace, Joseph MWallace, Joseph MWallace, Joseph MBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PBidwell, Joseph PBidwell, Joseph P and Bidwell, Joseph P
American journal of physiology. Endocrinology and metabolism, vol. 316, (no. 5), pp. E772, 2019-05-01. | Journal Article
 
Lrp4 Mediates Bone Homeostasis and Mechanotransduction through Interaction with Sclerostin In Vivo
Bullock, Whitney ABullock, Whitney ABullock, Whitney AHoggatt, April MHoggatt, April MHoggatt, April MHoran, Daniel JHoran, Daniel JHoran, Daniel JElmendorf, Andrew JElmendorf, Andrew JElmendorf, Andrew JSato, Amy YSato, Amy YSato, Amy YBellido, TeresitaBellido, TeresitaBellido, TeresitaLoots, Gabriela GLoots, Gabriela GLoots, Gabriela GPavalko, Fredrick MPavalko, Fredrick MPavalko, Fredrick MRobling, Alexander GRobling, Alexander G and Robling, Alexander G
iScience, vol. 20, (no. C), pp. 215, 2019-Oct-25. | Journal Article
 
Osteocytes and mechanical loading: The Wnt connection
Bullock, Whitney APavalko, Frederick M and Robling, Alexander G
Orthodontics & Craniofacial Research, vol. 22, (no. S1), pp. 179, May 2019. | Journal Article
 
Twist1 Inactivation in Dmp1-Expressing Cells Increases Bone Mass but Does Not Affect the Anabolic Response to Sclerostin Neutralization
Lewis, Karl JLewis, Karl JChoi, Roy BChoi, Roy B-JPemberton, Emily ZPemberton, Emily ZBullock, Whitney ABullock, Whitney AFirulli, Anthony BFirulli, Anthony BRobling, Alexander G and Robling, Alexander G
International journal of molecular sciences, vol. 20, (no. 18), pp. 4427, 2019-Sep-09. | Journal Article
2018
Conditional Deletion of Sost in MSC‐Derived Lineages Identifies Specific Cell‐Type Contributions to Bone Mass and B‐Cell Development
Yee, Cristal SManilay, Jennifer OChang, Jiun CHum, Nicholas RMurugesh, Deepa KBajwa, JamilaMendez, Melanie EEconomides, Aris EHoran, Daniel JRobling, Alexander G and Loots, Gabriela G
Journal of Bone and Mineral Research, vol. 33, (no. 10), pp. 1759, October 2018. | Journal Article
 
Finite Element Analysis of the Mouse Distal Femur with Tumor Burden in Response to Knee Loading.
Jiang, FeifeiJiang, FeifeiJiang, FeifeiLiu, ShengzhiLiu, ShengzhiLiu, ShengzhiChen, AndyChen, AndyChen, AndyLi, Bai-YanLi, Bai-YanLi, Bai-YanRobling, Alexander GRobling, Alexander GG. Robling, AlexanderChen, JieChen, JieChen, JieYokota, HirokiYokota, Hiroki and Yokota, Hiroki
International journal of orthopaedics (Hong Kong), vol. 5, (no. 1), pp. 863-871, 2018. | Journal Article
 
Finite-element analysis of the mouse proximal ulna in response to elbow loading.
Jiang, FeifeiJiang, FeifeiJiang, FeifeiJiang, FeifeiJalali, AydinJalali, AydinJalali, AydinJalali, AydinDeguchi, ChieDeguchi, ChieDeguchi, ChieDeguchi, ChieChen, AndyChen, AndyChen, AndyChen, AndyLiu, ShengzhiLiu, ShengzhiLiu, ShengzhiLiu, ShengzhiKondo, RikaKondo, RikaKondo, RikaKondo, RikaMinami, KazumasaMinami, KazumasaMinami, KazumasaMinami, KazumasaHoriuchi, TakashiHoriuchi, TakashiHoriuchi, TakashiHoriuchi, TakashiLi, Bai-YanLi, Bai-YanLi, Bai-YanLi, Bai-YanRobling, Alexander GRobling, AlexanderRobling, AlexanderRobling, Alexander G.Chen, JieChen, JieChen, JieChen, JieYokota, HirokiYokota, HirokiYokota, Hiroki and Yokota, Hiroki
Journal of bone and mineral metabolism, July 30, 2018. | Journal Article
 
Induction of Lrp5 HBM-causing mutations in Cathepsin-K expressing cells alters bone metabolism.
Kang, Kyung ShinKang, Kyung ShinHong, Jung MinHong, Jung MinHoran, Daniel JHoran, Daniel JLim, Kyung-EunLim, Kyung-EunBullock, Whitney ABullock, Whitney ABruzzaniti, AngelaBruzzaniti, AngelaHann, StevenHann, StevenWarman, Matthew LWarman, Matthew LRobling, Alexander G and Robling, Alexander G
Bone, vol. 120, pp. 166-175, October 25, 2018. | Journal Article
 
Inhibition of CaMKK2 Enhances Fracture Healing by Stimulating Indian Hedgehog Signaling and Accelerating Endochondral Ossification
Williams, Justin NWilliams, Justin NWilliams, Justin NWilliams, Justin NJN, WilliamsWilliams, Justin NKambrath, Anuradha ValiyaKambrath, Anuradha ValiyaKambrath, Anuradha ValiyaAV, KambrathKambrath, Anuradha ValiyaKambrath, Anuradha ValiyaPatel, Roshni BPatel, Roshni BPatel, Roshni BPatel, Roshni BPatel, Roshni BRB, PatelKang, Kyung ShinKang, Kyung ShinKS, KangKang, Kyung ShinKang, Kyung ShinKang, Kyung ShinMével, ElsaE, MévelMével, ElsaMével, ElsaMével, ElsaMével, ElsaLi, YongLi, YongY, LiLi, YongLi, YongLi, YongCheng, Ying‐HuaCheng, Ying-HuaCheng, Ying‐HuaCheng, Ying‐HuaCheng, Ying‐HuaYH, ChengPucylowski, Austin JPucylowski, Austin JPucylowski, Austin JPucylowski, Austin JPucylowski, Austin JAJ, PucylowskiHassert, Mariah AHassert, Mariah AHassert, Mariah AHassert, Mariah AHassert, Mariah AMA, HassertVoor, Michael JVoor, Michael JVoor, Michael JMJ, VoorVoor, Michael JVoor, Michael JKacena, Melissa AKacena, Melissa AKacena, Melissa AMA, KacenaKacena, Melissa AKacena, Melissa AThompson, William RThompson, William RThompson, William RThompson, William RWR, ThompsonThompson, William RWarden, Stuart JWarden, Stuart JWarden, Stuart JWarden, Stuart JWarden, Stuart JSJ, WardenBurr, David BBurr, David BBurr, David BBurr, David BBurr, David BDB, BurrU, SankarAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GRobling, Alexander GSankar, UmaSankar, UmaSankar, UmaSankar, Uma and Sankar, Uma
Journal of Bone and Mineral Research, vol. 33, (no. 5), pp. 944, May 2018. | Journal Article
 
Loss of mechanosensitive sclerostin may accelerate cranial bone growth and regeneration
Kang, Kyung ShinLastfogel, JeffAckerman, Laurie LJea, AndrewRobling, Alexander G and Tholpady, Sunil S
Journal of neurosurgery, vol. 129, (no. 4), pp. 1091, 2018-Oct. | Journal Article
 
Sclerostin neutralization unleashes the osteoanabolic effects of Dkk1 inhibition.
Witcher, Phillip CMiner, Sara EHoran, Daniel JBullock, Whitney ALim, Kyung-EunKang, Kyung ShinAdaniya, Alison LRoss, Ryan DLoots, Gabriela G and Robling, Alexander G
JCI insight, vol. 3, (no. 11), June 7, 2018. | Journal Article
 
Skeletal cell YAP and TAZ combinatorially promote bone development
Kegelman, Christopher D.Kegelman, Christopher DKegelman, Christopher DMason, Devon EMason, Devon E.Mason, Devon EDawahare, James H.Dawahare, James HDawahare, James HHoran, Daniel J.Horan, Daniel JHoran, Daniel JVigil, Genevieve DVigil, Genevieve D.Vigil, Genevieve DHoward, Scott S.Howard, Scott SHoward, Scott SRobling, Alexander G.Robling, Alexander GRobling, Alexander GBellido, Teresita M.Bellido, Teresita MBellido, Teresita MBoerckel, Joel DBoerckel, Joel D and Boerckel, Joel D.
The FASEB Journal, vol. 32, (no. 5), pp. 2721, May 2018. | Journal Article
 
The skeletal phenotype of achondrogenesis type 1A is caused exclusively by cartilage defects
Bird, Ian MBird, Ian MKim, Susie HKim, Susie HSchweppe, Devin KSchweppe, Devin KCaetano-Lopes, JoanaCaetano-Lopes, JoanaRobling, Alexander GRobling, Alexander GCharles, Julia FCharles, Julia FGygi, Steven PGygi, Steven PWarman, Matthew LWarman, Matthew LSmits, Patrick J and Smits, Patrick J
Development (Cambridge, England), vol. 145, (no. 1), pp. dev156588, 2018-01-08. | Journal Article
 
Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects.
Loots, Gabriela GRobling, Alexander GChang, Jiun CMurugesh, Deepa KBajwa, JamilaCarlisle, CameronManilay, Jennifer OWong, AliceYellowley, Clare E and Genetos, Damian C
Bone, August 30, 2018. | Journal Article
2017
Bone Mass and Strength are Significantly Improved in Mice Overexpressing Human WNT16 in Osteocytes
Alam, ImranulAlam, ImranulAlam, ImranulReilly, AustinReilly, AustinReilly, Austin MAlkhouli, MohammedAlkhouli, MohammedAlkhouli, MohammedGerard-O'Riley, Rita LGerard-O’Riley, RitaGerard-O’Riley, RitaKasipathi, CharishmaKasipathi, CharishmaKasipathi, CharishmaOakes, DanaOakes, DanaOakes, Dana KWright, WestonWright, WestonWright, Weston BActon, DenaActon, DenaActon, DenaMcQueen, AmieMcQueen, AmieMcQueen, Amie KPatel, BhavmikPatel, BhavmikPatel, BhavmikLim, Kyung-EunLim, Kyung-EunLim, Kyung-EunRobling, AlexanderRobling, AlexanderRobling, Alexander GEcons, MichaelEcons, Michael and Econs, Michael J
Calcified Tissue International, vol. 100, (no. 4), pp. 373, 20170400. | Journal Article