246 Publications (Page 4 of 10)
2011
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
M, KhannaCH, ChenA, Kimble-HillB, ParajuliS, Perez-MillerS, BaskaranJ, KimK, DriaV, VasiliouD, Mochly-Rosen and TD, Hurley
 
Discovery of novel regulators of aldehyde dehydrogenase isoenzymes.
B, ParajuliAC, Kimble-HillM, KhannaY, IvanovaS, Meroueh and TD, Hurley
 
Discovery of novel regulators of aldehyde dehydrogenase isoenzymes.
Parajuli, BibekParajuli, BibekKimble Hill, Ann CKimble-Hill, Ann CKhanna, MayKhanna, MayIvanova, YvelinaIvanova, YvelinaMeroueh, SamyMeroueh, SamyHurley, Thomas D and Hurley, Thomas D
Chemico-biological interactions, vol. 191, (no. 1-3), pp. 153-8, 2011/May/30. | Journal Article
 
Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen.
S, BaskaranVM, ChikwanaCJ, ContrerasKD, DavisWA, WilsonAA, DePaoli-RoachPJ, Roach and TD, Hurley
 
Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen.
Baskaran, SulochanadeviChikwana, Vimbai MContreras, Christopher JDavis, Keri DWilson, Wayne ADePaoli-Roach, Anna ADepaoli Roach, Anna ARoach, Peter J and Hurley, Thomas D
The Journal of biological chemistry, vol. 286, (no. 39), pp. 33999-4006, 2011/Sep/30. | Journal Article
 
Phosphate incorporation during glycogen synthesis and Lafora disease.
VS, TagliabracciC, HeissC, KarthikCJ, ContrerasJ, GlushkaM, IshiharaP, AzadiTD, HurleyAA, DePaoli-Roach and PJ, Roach
 
Phosphate incorporation during glycogen synthesis and Lafora disease.
Tagliabracci, Vincent STagliabracci, V.S.Heiss, C.Heiss, ChristianKarthik, C.Karthik, ChandraContreras, C.J.Contreras, Christopher JGlushka, JohnGlushka, J.Ishihara, M.Ishihara, MayumiAzadi, P.Azadi, ParastooHurley, Thomas DHurley, T.D.DePaoli-Roach, Anna ADepaoli-Roach, A.A.Depaoli Roach, Anna ARoach, Peter J and Roach, P.J.
Cell metabolism, vol. 13, (no. 3), pp. 274-82, 2011/Mar/2. | Journal Article
 
Structure Based Inhibition of Mitochondrial Aldehyde Dehydrogenase (ALDH2) Activity
Kimble-Hill, Ann CKimble-Hill, Ann CKimble Hill, Ann CYounus, HinaYounus, HinaYounus, HinaMeroueh, SamyMeroueh, SamyMeroueh, SamyHurley, Thomas DHurley, Thomas D and Hurley, Thomas D
Biophysical Journal, vol. 100, (no. 3), pp. 215a, 2011. | Journal Article
2010
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
Perez-miller, SamanthaYounus, HinaVanam, RamChen, Che-hongMochly Rosen, Daria D and Hurley, Thomas D
Nature Structural & Molecular Biology, vol. 17, (no. 2), pp. 159-64, Feb 2010. | Journal Article
 
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.
S, Perez-MillerH, YounusR, VanamCH, ChenD, Mochly-Rosen and TD, Hurley
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Perez-Miller, SamanthaZou, QinNovotny, Milos V and Hurley, Thomas D
Protein science : a publication of the Protein Society, vol. 19, (no. 8), pp. 1469-79, 2010/Aug. | Journal Article
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
S, Perez-MillerQ, ZouMV, Novotny and TD, Hurley
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
Allen, Erin MAnderson, David GFlorang, Virginia RKhanna, MayHurley, Thomas D and Doorn, Jonathan A
Chemical research in toxicology, vol. 23, (no. 11), pp. 1843-50, 2010/Nov/15. | Journal Article
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
EM, AllenDG, AndersonVR, FlorangM, KhannaTD, Hurley and JA, Doorn
 
Structural basis for glucose-6-phosphate activation of glycogen synthase
Baskaran, SulochanadeviBaskaran, SulochanadeviRoach, PeterRoach, Peter JDepaoli Roach, Anna ADePaoli-Roach, AnnaDePaoli-Roach, Anna AHurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 107, (no. 41), Oct 12, 2010. | Journal Article
 
Structural basis for glucose-6-phosphate activation of glycogen synthase.
S, BaskaranPJ, RoachAA, DePaoli-Roach and TD, Hurley
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
Baraibar, Martin ABaraibar, MartinMuhoberac, BarryMuhoberac, Barry BGarringer, Holly JGarringer, HollyHurley, Thomas DHurley, ThomasVidal, Ruben and Vidal, Ruben G
The Journal of biological chemistry, vol. 285, (no. 3), pp. 1950-6, 2010/Jan/15. | Journal Article
2009
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: Synthesis of N-acyl glycinals
Aneetha, HalikhedkarO'Dell, David KTan, BoWalker, J. M and Hurley, Thomas D
Bioorganic and Medicinal Chemistry Letters, vol. 19, (no. 1), pp. 237-241, 2009. | Journal Article
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, BaraibarBB, MuhoberacHJ, GarringerTD, Hurley and R, Vidal
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, BaraibarBB, MuhoberacHJ, GarringerTD, Hurley and R, Vidal
The Journal of biological chemistry. | Journal Article
2008
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.
CH, ChenGR, BudasEN, ChurchillMH, DisatnikTD, Hurley and D, Mochly-Rosen
 
Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart
Chen, Che-HongBudas, GrantChurchill, Eric NDisatnik, Marie-HeleneHurley, Thomas D and Mochly Rosen, Daria D
Science, vol. 321, (no. 5895), pp. 1493-1495, Sep 12, 2008. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, AneethaDK, O’DellB, TanJM, Walker and TD, Hurley
Bioorganic & medicinal chemistry letters. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, AneethaDK, O’DellB, TanJM, Walker and TD, Hurley
 
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
WL, WangSC, ChaiM, HuangHZ, HeTD, Hurley and QZ, Ye