246 Publications (Page 5 of 10)
2008
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
Wang, Wen-Long⋅WL, Wang⋅Chai, Sergio⋅SC, Chai⋅Huang, Min⋅M, Huang⋅He, Hong-Zhen⋅HZ, He⋅Hurley, Thomas D⋅TD, Hurley⋅Ye, Qi Zhuang and QZ, Ye
Journal of medicinal chemistry. | Journal Article
2007
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme.
Janecki, Dariusz J⋅Bemis, Kerry G⋅Tegeler, Tony J⋅Sanghani, Paresh C⋅Zhai, Lanmin⋅Hurley, Thomas D⋅Bosron, William F and Wang, Mu
Analytical biochemistry, vol. 369, (no. 1), pp. 18-26, 2007/Oct/1. | Journal Article
 
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme.
DJ, Janecki⋅KG, Bemis⋅TJ, Tegeler⋅PC, Sanghani⋅L, Zhai⋅TD, Hurley⋅WF, Bosron and M, Wang
 
Inhibition of the oxidative metabolism of 3,4-dihydroxyphenylacetaldehyde, a reactive intermediate of dopamine metabolism, by 4-hydroxy-2-nonenal.
Florang, V R⋅Rees, J N⋅Brogden, N K⋅Anderson, D G⋅Hurley, Thomas D and Doorn, Jonathan A
Neurotoxicology, vol. 28, (no. 1), pp. 76-82, 2007/Jan. | Journal Article
 
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Bateman, Raynard L⋅Ashworth, Justin⋅Witte, John F⋅Baker, L-J⋅Bhanumoorthy, Pullooru⋅Timm, David E⋅Hurley, Thomas D⋅Grompe, Markus and McClard, Ronald W
The Biochemical journal, vol. 402, (no. 2), pp. 251-60, 2007/Mar/1. | Journal Article
 
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
RL, Bateman⋅J, Ashworth⋅JF, Witte⋅LJ, Baker⋅P, Bhanumoorthy⋅DE, Timm⋅TD, Hurley⋅M, Grompe and RW, McClard
 
Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes
Ma, Ze-Qiang⋅Ma, Ze-Qiang⋅Xie, Sheng-Xue⋅Xie, Sheng-Xue⋅Huang, Qing-Qing⋅Huang, Qing-Qing⋅Nan, Fa-Jun⋅Nan, Fa-Jun⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Ye, Qi-Zhuang and Ye, Qi Zhuang
BMC structural biology, vol. 7, (no. 1), pp. 84, 2007-Dec-19. | Journal Article
 
Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes.
Ma, Ze-Qiang⋅ZQ, Ma⋅Xie, Sheng-Xue⋅SX, Xie⋅Huang, Qing-Qing⋅QQ, Huang⋅Nan, Fa-Jun⋅FJ, Nan⋅Hurley, Thomas D⋅TD, Hurley⋅Ye, Qi Zhuang and QZ, Ye
BMC structural biology. | Journal Article
 
Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop adaptability in selective inhibition of bacterial enzymes.
ZQ, Ma⋅SX, Xie⋅QQ, Huang⋅FJ, Nan⋅TD, Hurley and QZ, Ye
 
Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
Larson, Heather N⋅Larson, Heather N⋅Zhou, Jianzhong⋅Zhou, Jianzhong⋅Chen, Zhiqiang⋅Chen, Zhiqiang⋅Stamler, Jonathan S⋅Stamler, Jonathan S⋅Weiner, Henry⋅Weiner, Henry⋅Hurley, Thomas D and Hurley, Thomas D
The Journal of biological chemistry, vol. 282, (no. 17), pp. 12940-50, 2007/Apr/27. | Journal Article
 
Structural and functional consequences of coenzyme binding to the inactive asian variant of mitochondrial aldehyde dehydrogenase: roles of residues 475 and 487.
HN, Larson⋅J, Zhou⋅Z, Chen⋅JS, Stamler⋅H, Weiner and TD, Hurley
 
Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
Hurley, Thomas D⋅Yang, Jie⋅Zhang, Lili⋅Goodwin, Kristie D⋅Zou, Qin⋅Cortese, Marc⋅Dunker, A K and Depaoli Roach, Anna A
The Journal of biological chemistry, vol. 282, (no. 39), pp. 28874-83, 2007/Sep/28. | Journal Article
 
Structural basis for regulation of protein phosphatase 1 by inhibitor-2.
TD, Hurley⋅J, Yang⋅L, Zhang⋅KD, Goodwin⋅Q, Zou⋅M, Cortese⋅AK, Dunker and AA, DePaoli-Roach
 
Ternary complex formation and induced asymmetry in orotate phosphoribosyltransferase.
L, González-Segura⋅JF, Witte⋅RW, McClard and TD, Hurley
 
Ternary Complex Formation and Induced Asymmetry in Orotate Phosphoribosyltransferase
Gonzalez-Segura, Lilian⋅Witte, John F⋅McClard, Ronald W and Hurley, Thomas D
Biochemistry (Washington), vol. 46, (no. 49), pp. 14075-14086, 2007. | Journal Article
2006
Absolute Quantification of ADH Isoenzymes in Human Liver using Multiple Reaction Monitoring (MRM) Method
Janecki, Dariusz J⋅Tegeler, Tony⋅Bemis, Kerry⋅Hurley, Thomas D⋅Bosron, William F and Wang, Mu
54th ASMS Conference Proceedings, 2006. | Journal Article
 
Direct detection of glycogenin reaction products during glycogen initiation.
TD, Hurley⋅C, Walls⋅JR, Bennett⋅PJ, Roach and M, Wang
 
Direct detection of glycogenin reaction products during glycogen initiation.
Hurley, Thomas D⋅Hurley, Thomas D⋅Walls, Chad⋅Walls, Chad⋅Bennett, John R⋅Bennett, John R⋅Roach, Peter J⋅Roach, Peter J⋅Wang, Mu and Wang, Mu
Biochemical and biophysical research communications, vol. 348, (no. 2), pp. 374-8, 2006/Sep/22. | Journal Article
 
Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal.
JA, Doorn⋅TD, Hurley and DR, Petersen
 
Inhibition of human mitochondrial aldehyde dehydrogenase by 4-hydroxynon-2-enal and 4-oxonon-2-enal.
Doorn, Jonathan A⋅Hurley, Thomas D and Petersen, Dennis R
Chemical research in toxicology, vol. 19, (no. 1), pp. 102-10, 2006/Jan. | Journal Article
 
Inhibition of the oxidative metabolism of 3,4-dihydroxyphenylacetaldehyde, a reactive intermediate of dopamine metabolism, by 4-hydroxy-2-nonenal.
VR, Florang⋅JN, Rees⋅NK, Brogden⋅DG, Anderson⋅TD, Hurley and JA, Doorn
 
Inhibition of the oxidative metabolism of 3,4-dihydroxyphenylacetaldehyde, a reactive intermediate of dopamine metabolism, by 4-hydroxy-2-nonenal.
VR, Florang⋅JN, Rees⋅NK, Brogden⋅DG, Anderson⋅TD, Hurley and JA, Doorn
Neurotoxicology. | Journal Article
 
Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis.
Ho, Kwok K⋅Hurley, Thomas D and Weiner, Henry
Biochemistry, vol. 45, (no. 31), pp. 9445-53, 2006/Aug/8. | Journal Article
 
Selective alteration of the rate-limiting step in cytosolic aldehyde dehydrogenase through random mutagenesis.
KK, Ho⋅TD, Hurley and H, Weiner
2005
Differential effects of Mg2+ ions on the individual kinetic steps of human cytosolic and mitochondrial aldehyde dehydrogenases.
Ho, Kwok K⋅Ho, Kwok⋅Ho, Kwok⋅Allai-Hassani, Abdellah⋅Allali-Hassani, Abdellah⋅Allai-Hassani, Abdellah⋅Hurley, Thomas⋅Hurley, Thomas⋅Hurley, Thomas D⋅Weiner, Henry⋅Weiner, Henry and Weiner, Henry
Biochemistry, vol. 44, (no. 22), pp. 8022-9, 2005/Jun/7. | Journal Article