240 Publications (Page 4 of 10)
2011
Phosphate incorporation during glycogen synthesis and Lafora disease.
VS, Tagliabracci⋅C, Heiss⋅C, Karthik⋅CJ, Contreras⋅J, Glushka⋅M, Ishihara⋅P, Azadi⋅TD, Hurley⋅AA, DePaoli-Roach and PJ, Roach
 
Structure Based Inhibition of Mitochondrial Aldehyde Dehydrogenase (ALDH2) Activity
Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble Hill, Ann C⋅Younus, Hina⋅Younus, Hina⋅Younus, Hina⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Hurley, Thomas D⋅Hurley, Thomas D and Hurley, Thomas D
Biophysical Journal, vol. 100, (no. 3), pp. 215a, 2011. | Journal Article
2010
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
Perez-miller, Samantha⋅Younus, Hina⋅Vanam, Ram⋅Chen, Che-hong⋅Mochly Rosen, Daria D and Hurley, Thomas D
Nature Structural & Molecular Biology, vol. 17, (no. 2), pp. 159-64, Feb 2010. | Journal Article
 
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.
S, Perez-Miller⋅H, Younus⋅R, Vanam⋅CH, Chen⋅D, Mochly-Rosen and TD, Hurley
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Perez-Miller, Samantha⋅Zou, Qin⋅Novotny, Milos V and Hurley, Thomas D
Protein science : a publication of the Protein Society, vol. 19, (no. 8), pp. 1469-79, 2010/Aug. | Journal Article
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
S, Perez-Miller⋅Q, Zou⋅MV, Novotny and TD, Hurley
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
Allen, Erin M⋅Anderson, David G⋅Florang, Virginia R⋅Khanna, May⋅Hurley, Thomas D and Doorn, Jonathan A
Chemical research in toxicology, vol. 23, (no. 11), pp. 1843-50, 2010/Nov/15. | Journal Article
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
EM, Allen⋅DG, Anderson⋅VR, Florang⋅M, Khanna⋅TD, Hurley and JA, Doorn
 
Structural basis for glucose-6-phosphate activation of glycogen synthase
Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅Roach, Peter J⋅Roach, Peter⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅DePaoli-Roach, Anna A⋅Hurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 107, (no. 41), Oct 12, 2010. | Journal Article
 
Structural basis for glucose-6-phosphate activation of glycogen synthase.
S, Baskaran⋅PJ, Roach⋅AA, DePaoli-Roach and TD, Hurley
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
Baraibar, Martin A⋅Baraibar, Martin⋅Muhoberac, Barry⋅Muhoberac, Barry B⋅Garringer, Holly J⋅Garringer, Holly⋅Hurley, Thomas D⋅Hurley, Thomas⋅Vidal, Ruben and Vidal, Ruben G
The Journal of biological chemistry, vol. 285, (no. 3), pp. 1950-6, 2010/Jan/15. | Journal Article
2009
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: Synthesis of N-acyl glycinals
Aneetha, Halikhedkar⋅O'Dell, David K⋅Tan, Bo⋅Walker, J. M and Hurley, Thomas D
Bioorganic and Medicinal Chemistry Letters, vol. 19, (no. 1), pp. 237-241, 2009. | Journal Article
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, Baraibar⋅BB, Muhoberac⋅HJ, Garringer⋅TD, Hurley and R, Vidal
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, Baraibar⋅BB, Muhoberac⋅HJ, Garringer⋅TD, Hurley and R, Vidal
The Journal of biological chemistry. | Journal Article
2008
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.
CH, Chen⋅GR, Budas⋅EN, Churchill⋅MH, Disatnik⋅TD, Hurley and D, Mochly-Rosen
 
Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart
Chen, Che-Hong⋅Budas, Grant⋅Churchill, Eric N⋅Disatnik, Marie-Helene⋅Hurley, Thomas D and Mochly Rosen, Daria D
Science, vol. 321, (no. 5895), pp. 1493-1495, Sep 12, 2008. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, Aneetha⋅DK, O’Dell⋅B, Tan⋅JM, Walker and TD, Hurley
Bioorganic & medicinal chemistry letters. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, Aneetha⋅DK, O’Dell⋅B, Tan⋅JM, Walker and TD, Hurley
 
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
WL, Wang⋅SC, Chai⋅M, Huang⋅HZ, He⋅TD, Hurley and QZ, Ye
 
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
Wang, Wen-Long⋅WL, Wang⋅Chai, Sergio⋅SC, Chai⋅Huang, Min⋅M, Huang⋅He, Hong-Zhen⋅HZ, He⋅Hurley, Thomas D⋅TD, Hurley⋅Ye, Qi Zhuang and QZ, Ye
Journal of medicinal chemistry. | Journal Article
2007
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme.
DJ, Janecki⋅KG, Bemis⋅TJ, Tegeler⋅PC, Sanghani⋅L, Zhai⋅TD, Hurley⋅WF, Bosron and M, Wang
 
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme.
Janecki, Dariusz J⋅Bemis, Kerry G⋅Tegeler, Tony J⋅Sanghani, Paresh C⋅Zhai, Lanmin⋅Hurley, Thomas D⋅Bosron, William F and Wang, Mu
Analytical biochemistry, vol. 369, (no. 1), pp. 18-26, 2007/Oct/1. | Journal Article
 
Inhibition of the oxidative metabolism of 3,4-dihydroxyphenylacetaldehyde, a reactive intermediate of dopamine metabolism, by 4-hydroxy-2-nonenal.
Florang, V R⋅Rees, J N⋅Brogden, N K⋅Anderson, D G⋅Hurley, Thomas D and Doorn, Jonathan A
Neurotoxicology, vol. 28, (no. 1), pp. 76-82, 2007/Jan. | Journal Article
 
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
Bateman, Raynard L⋅Ashworth, Justin⋅Witte, John F⋅Baker, L-J⋅Bhanumoorthy, Pullooru⋅Timm, David E⋅Hurley, Thomas D⋅Grompe, Markus and McClard, Ronald W
The Biochemical journal, vol. 402, (no. 2), pp. 251-60, 2007/Mar/1. | Journal Article
 
Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics.
RL, Bateman⋅J, Ashworth⋅JF, Witte⋅LJ, Baker⋅P, Bhanumoorthy⋅DE, Timm⋅TD, Hurley⋅M, Grompe and RW, McClard