246 Publications (Page 4 of 10)
2011
Discovery of a novel class of covalent inhibitor for aldehyde dehydrogenases.
M, Khanna⋅CH, Chen⋅A, Kimble-Hill⋅B, Parajuli⋅S, Perez-Miller⋅S, Baskaran⋅J, Kim⋅K, Dria⋅V, Vasiliou⋅D, Mochly-Rosen and TD, Hurley
 
Discovery of novel regulators of aldehyde dehydrogenase isoenzymes.
B, Parajuli⋅AC, Kimble-Hill⋅M, Khanna⋅Y, Ivanova⋅S, Meroueh and TD, Hurley
 
Discovery of novel regulators of aldehyde dehydrogenase isoenzymes.
Parajuli, Bibek⋅Parajuli, Bibek⋅Kimble Hill, Ann C⋅Kimble-Hill, Ann C⋅Khanna, May⋅Khanna, May⋅Ivanova, Yvelina⋅Ivanova, Yvelina⋅Meroueh, Samy⋅Meroueh, Samy⋅Hurley, Thomas D and Hurley, Thomas D
Chemico-biological interactions, vol. 191, (no. 1-3), pp. 153-8, 2011/May/30. | Journal Article
 
Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen.
S, Baskaran⋅VM, Chikwana⋅CJ, Contreras⋅KD, Davis⋅WA, Wilson⋅AA, DePaoli-Roach⋅PJ, Roach and TD, Hurley
 
Multiple glycogen-binding sites in eukaryotic glycogen synthase are required for high catalytic efficiency toward glycogen.
Baskaran, Sulochanadevi⋅Chikwana, Vimbai M⋅Contreras, Christopher J⋅Davis, Keri D⋅Wilson, Wayne A⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Roach, Peter J and Hurley, Thomas D
The Journal of biological chemistry, vol. 286, (no. 39), pp. 33999-4006, 2011/Sep/30. | Journal Article
 
Phosphate incorporation during glycogen synthesis and Lafora disease.
VS, Tagliabracci⋅C, Heiss⋅C, Karthik⋅CJ, Contreras⋅J, Glushka⋅M, Ishihara⋅P, Azadi⋅TD, Hurley⋅AA, DePaoli-Roach and PJ, Roach
 
Phosphate incorporation during glycogen synthesis and Lafora disease.
Tagliabracci, Vincent S⋅Tagliabracci, V.S.⋅Heiss, C.⋅Heiss, Christian⋅Karthik, C.⋅Karthik, Chandra⋅Contreras, C.J.⋅Contreras, Christopher J⋅Glushka, John⋅Glushka, J.⋅Ishihara, M.⋅Ishihara, Mayumi⋅Azadi, P.⋅Azadi, Parastoo⋅Hurley, Thomas D⋅Hurley, T.D.⋅DePaoli-Roach, Anna A⋅Depaoli-Roach, A.A.⋅Depaoli Roach, Anna A⋅Roach, Peter J and Roach, P.J.
Cell metabolism, vol. 13, (no. 3), pp. 274-82, 2011/Mar/2. | Journal Article
 
Structure Based Inhibition of Mitochondrial Aldehyde Dehydrogenase (ALDH2) Activity
Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble Hill, Ann C⋅Younus, Hina⋅Younus, Hina⋅Younus, Hina⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Hurley, Thomas D⋅Hurley, Thomas D and Hurley, Thomas D
Biophysical Journal, vol. 100, (no. 3), pp. 215a, 2011. | Journal Article
2010
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant
Perez-miller, Samantha⋅Younus, Hina⋅Vanam, Ram⋅Chen, Che-hong⋅Mochly Rosen, Daria D and Hurley, Thomas D
Nature Structural & Molecular Biology, vol. 17, (no. 2), pp. 159-64, Feb 2010. | Journal Article
 
Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant.
S, Perez-Miller⋅H, Younus⋅R, Vanam⋅CH, Chen⋅D, Mochly-Rosen and TD, Hurley
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
Perez-Miller, Samantha⋅Zou, Qin⋅Novotny, Milos V and Hurley, Thomas D
Protein science : a publication of the Protein Society, vol. 19, (no. 8), pp. 1469-79, 2010/Aug. | Journal Article
 
High resolution X-ray structures of mouse major urinary protein nasal isoform in complex with pheromones.
S, Perez-Miller⋅Q, Zou⋅MV, Novotny and TD, Hurley
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
Allen, Erin M⋅Anderson, David G⋅Florang, Virginia R⋅Khanna, May⋅Hurley, Thomas D and Doorn, Jonathan A
Chemical research in toxicology, vol. 23, (no. 11), pp. 1843-50, 2010/Nov/15. | Journal Article
 
Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.
EM, Allen⋅DG, Anderson⋅VR, Florang⋅M, Khanna⋅TD, Hurley and JA, Doorn
 
Structural basis for glucose-6-phosphate activation of glycogen synthase
Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅Roach, Peter⋅Roach, Peter J⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅DePaoli-Roach, Anna A⋅Hurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 107, (no. 41), Oct 12, 2010. | Journal Article
 
Structural basis for glucose-6-phosphate activation of glycogen synthase.
S, Baskaran⋅PJ, Roach⋅AA, DePaoli-Roach and TD, Hurley
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
Baraibar, Martin A⋅Baraibar, Martin⋅Muhoberac, Barry⋅Muhoberac, Barry B⋅Garringer, Holly J⋅Garringer, Holly⋅Hurley, Thomas D⋅Hurley, Thomas⋅Vidal, Ruben and Vidal, Ruben G
The Journal of biological chemistry, vol. 285, (no. 3), pp. 1950-6, 2010/Jan/15. | Journal Article
2009
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: Synthesis of N-acyl glycinals
Aneetha, Halikhedkar⋅O'Dell, David K⋅Tan, Bo⋅Walker, J. M and Hurley, Thomas D
Bioorganic and Medicinal Chemistry Letters, vol. 19, (no. 1), pp. 237-241, 2009. | Journal Article
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, Baraibar⋅BB, Muhoberac⋅HJ, Garringer⋅TD, Hurley and R, Vidal
 
Unraveling of the E-helices and disruption of 4-fold pores are associated with iron mishandling in a mutant ferritin causing neurodegeneration.
MA, Baraibar⋅BB, Muhoberac⋅HJ, Garringer⋅TD, Hurley and R, Vidal
The Journal of biological chemistry. | Journal Article
2008
Activation of aldehyde dehydrogenase-2 reduces ischemic damage to the heart.
CH, Chen⋅GR, Budas⋅EN, Churchill⋅MH, Disatnik⋅TD, Hurley and D, Mochly-Rosen
 
Activation of Aldehyde Dehydrogenase-2 Reduces Ischemic Damage to the Heart
Chen, Che-Hong⋅Budas, Grant⋅Churchill, Eric N⋅Disatnik, Marie-Helene⋅Hurley, Thomas D and Mochly Rosen, Daria D
Science, vol. 321, (no. 5895), pp. 1493-1495, Sep 12, 2008. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, Aneetha⋅DK, O’Dell⋅B, Tan⋅JM, Walker and TD, Hurley
Bioorganic & medicinal chemistry letters. | Journal Article
 
Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: synthesis of N-acyl glycinals.
H, Aneetha⋅DK, O’Dell⋅B, Tan⋅JM, Walker and TD, Hurley
 
Discovery of inhibitors of Escherichia coli methionine aminopeptidase with the Fe(II)-form selectivity and antibacterial activity.
WL, Wang⋅SC, Chai⋅M, Huang⋅HZ, He⋅TD, Hurley and QZ, Ye