246 Publications (Page 2 of 10)
2016
Incorporation of phosphate into glycogen by glycogen synthase.
CJ, Contreras⋅DM, Segvich⋅K, Mahalingan⋅VM, Chikwana⋅TL, Kirley⋅TD, Hurley⋅AA, DePaoli-Roach and PJ, Roach
 
Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells.
J, Li⋅S, Condello⋅J, Thomes-Pepin⋅X, Ma⋅Y, Xia⋅TD, Hurley⋅D, Matei and JX, Cheng
 
Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells.
J, Li⋅Li, Junjie⋅Condello, Salvatore⋅S, Condello⋅J, Thomes-Pepin⋅Thomes-Pepin, Jessica⋅X, Ma⋅Ma, Xiaoxiao⋅Xia, Yu⋅Y, Xia⋅Hurley, Thomas D⋅TD, Hurley⋅D, Matei⋅Matei, Daniela⋅JX, Cheng and Cheng, Ji-Xin
Cell stem cell. | Journal Article
 
Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
Mahalingan, Krishna K⋅Mahalingan, Krishna K⋅Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Roach, Peter J⋅Roach, Peter J⋅Hurley, Thomas D and Hurley, Thomas D
Biochemistry, December 20, 2016. | Journal Article
 
Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation.
KK, Mahalingan⋅S, Baskaran⋅AA, DePaoli-Roach⋅PJ, Roach and TD, Hurley
2015
Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.
CA, Morgan and TD, Hurley
 
Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.
Morgan, Cynthia A and Hurley, Thomas D
Journal of medicinal chemistry, vol. 58, (no. 4), pp. 1964-1975, February 26, 2015. | Journal Article
 
Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
Morgan, Cynthia A and Hurley, Thomas D
Chemico-biological interactions, vol. 234, pp. 29-37, June 5, 2015. | Journal Article
 
Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.
CD, Buchman⋅KK, Mahalingan and TD, Hurley
Chemico-biological interactions. | Journal Article
 
Discovery of a series of aromatic lactones as ALDH1/2-directed inhibitors.
CD, Buchman⋅KK, Mahalingan and TD, Hurley
 
Hominids adapted to metabolize ethanol long before human-directed fermentation.
Carrigan, Matthew A⋅Uryasev, Oleg⋅Frye, Carole B⋅Eckman, Blair L⋅Myers, Candace R⋅Hurley, Thomas D and Benner, Steven A
Proceedings of the National Academy of Sciences of the United States of America, vol. 112, (no. 2), pp. 458-463, January 13, 2015. | Journal Article
 
N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
Morgan, Cynthia A⋅Parajuli, Bibek⋅Buchman, Cameron D⋅Dria, Karl and Hurley, Thomas D
Chemico-biological interactions, vol. 234, pp. 18-28, June 5, 2015. | Journal Article
 
β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids.
Condello, S⋅Morgan, C A⋅Nagdas, S⋅Cao, L⋅Turek, J⋅Hurley, T D and Matei, D
Oncogene, vol. 34, (no. 18), pp. 2297-2308, April 30, 2015. | Journal Article
2014
Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
CA, Morgan and TD, Hurley
Chemico-biological interactions. | Journal Article
 
Development of a high-throughput in vitro assay to identify selective inhibitors for human ALDH1A1.
CA, Morgan and TD, Hurley
 
Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.
AC, Kimble-Hill⋅B, Parajuli⋅CH, Chen⋅D, Mochly-Rosen and TD, Hurley
 
Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones.
Kimble-Hill, Ann C⋅Kimble Hill, Ann C⋅Parajuli, Bibek⋅Parajuli, Bibek⋅Chen, Che-Hong⋅Chen, Che-Hong⋅Mochly-Rosen, Daria⋅Mochly Rosen, Daria D⋅Hurley, Thomas D and Hurley, Thomas D
Journal of medicinal chemistry, vol. 57, (no. 3), pp. 714-22, 2014/Feb/13. | Journal Article
 
Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
B, Parajuli⋅TM, Georgiadis⋅ML, Fishel and TD, Hurley
 
Development of selective inhibitors for human aldehyde dehydrogenase 3A1 (ALDH3A1) for the enhancement of cyclophosphamide cytotoxicity.
Parajuli, Bibek⋅Parajuli, Bibek⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Hurley, Thomas D and Hurley, Thomas D
Chembiochem : a European journal of chemical biology, vol. 15, (no. 5), pp. 701-712, March 21, 2014. | Journal Article
 
Enrichment of chemical libraries docked to protein conformational ensembles and application to aldehyde dehydrogenase 2.
B, Wang⋅CD, Buchman⋅L, Li⋅TD, Hurley and SO, Meroueh
 
Enrichment of Chemical Libraries Docked to Protein Conformational Ensembles and Application to Aldehyde Dehydrogenase 2
Wang, Bo⋅Buchman, Cameron D⋅Li, Liwei⋅Hurley, Thomas D and Meroueh, Samy
Journal of Chemical Information and Modeling, vol. 54, (no. 7), Jul 28, 2014. | Journal Article
 
Hominids adapted to metabolize ethanol long before human-directed fermentation.
MA, Carrigan⋅O, Uryasev⋅CB, Frye⋅BL, Eckman⋅CR, Myers⋅TD, Hurley and SA, Benner
 
Hominids adapted to metabolize ethanol long before human-directed fermentation.
MA, Carrigan⋅O, Uryasev⋅CB, Frye⋅BL, Eckman⋅CR, Myers⋅TD, Hurley and SA, Benner
Proceedings of the National Academy of Sciences of the United States of America. | Journal Article
 
N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
CA, Morgan⋅B, Parajuli⋅CD, Buchman⋅K, Dria and TD, Hurley
 
N,N-diethylaminobenzaldehyde (DEAB) as a substrate and mechanism-based inhibitor for human ALDH isoenzymes.
CA, Morgan⋅B, Parajuli⋅CD, Buchman⋅K, Dria and TD, Hurley
Chemico-biological interactions. | Journal Article