348 Publications (Page 4 of 14)
2018
Abstract 1386: Safety and tolerability of guadecitabine (SGI-110) plus cisplatin in patients with platinum refractory germ cell tumors (GCT): A phase 1 studyAlbany, Costantine⋅Albany, Costantine⋅Hashemi, Neda S⋅Hashemi, Neda S⋅Fang, Fang⋅Fang, Fang⋅Lowder, James⋅Lowder, James⋅Einhorn, Lawrence⋅Einhorn, Lawrence⋅Nephew, Kenneth and Nephew, KennethCancer Research, vol. 78, (no. 13 Supplement), pp. 1386, 2018-07-01.
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Abstract 2997: Epigenomic signatures of acquired platinum resistance in high grade serous ovarian cancerFang, Fang⋅Cardenas, Horacio⋅Jiang, Guanglong⋅Perkins, Susan M⋅Zhang, Chi⋅Keer, Harold⋅Liu, Yunlong⋅Matei, Daniela and Nephew, KennethCancer Research, vol. 78, (no. 13 Supplement), pp. 2997, 2018-07-01.
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Abstract 4319: Epigenetic reprogramming associated with BRCA1 loss of function in ovarian cancer induces enhanced interferon gamma signalingCardenas, Horacio⋅Cardenas, Horacio⋅Pepin, Jessica Thomes⋅Pepin, Jessica Thomes⋅Jiang, Guanglong⋅Jiang, Guanglong⋅Condello, Salvatore⋅Condello, Salvatore⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Liu, Yunlong⋅Liu, Yunlong⋅Matei, Daniela and Matei, DanielaCancer Research, vol. 78, (no. 13 Supplement), pp. 4319, 2018-07-01.
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An Effective Epigenetic-PARP Inhibitor Combination Therapy for Breast and Ovarian Cancers Independent of BRCA MutationsPulliam, Nicholas⋅Pulliam, Nicholas⋅Pulliam, Nicholas⋅Fang, Fang⋅Fang, Fang⋅Fang, Fang⋅Ozes, Ali R⋅Ozes, Ali R⋅Ozes, Ali R⋅Tang, Jessica⋅Tang, Jessica⋅Tang, Jessica⋅Adewuyi, Adeoluwa⋅Adewuyi, Adeoluwa⋅Adewuyi, Adeoluwa⋅Keer, Harold⋅Keer, Harold⋅Keer, Harold⋅Lyons, John⋅Lyons, John⋅Lyons, John⋅Baylin, Stephen B⋅Baylin, Stephen B⋅Baylin, Stephen B⋅Matei, Daniela⋅Matei, Daniela⋅Matei, Daniela⋅Nakshatri, Harikrishna⋅Nakshatri, Harikrishna⋅Nakshatri, Harikrishna⋅Rassool, Feyruz V⋅Rassool, Feyruz V⋅Rassool, Feyruz V⋅Miller, Kathy D⋅Miller, Kathy D⋅Miller, Kathy D⋅Nephew, Kenneth P⋅Nephew, Kenneth P and Nephew, Kenneth PClinical cancer research : an official journal of the American Association for Cancer Research, vol. 24, (no. 13), pp. 3175, 2018-Jul-01.
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A Phase I Clinical Trial of Guadecitabine and Carboplatin in Platinum-Resistant, Recurrent Ovarian Cancer: Clinical, Pharmacokinetic, and Pharmacodynamic AnalysesMatei, Daniela⋅Matei, Daniela⋅Matei, Daniela⋅Matei, Daniela⋅Matei, Daniela⋅Ghamande, Sharad⋅Ghamande, Sharad⋅Ghamande, Sharad⋅Roman, Lynda⋅Roman, Lynda⋅Roman, Lynda⋅Roman, Lynda⋅Roman, Lynda⋅Secord, Angeles⋅Alvarez Secord, Angeles⋅Alvarez Secord, Angeles⋅Nemunaitis, John⋅Nemunaitis, John⋅Nemunaitis, John⋅Nemunaitis, John⋅Nemunaitis, John⋅Markham, Merry⋅Markham, Merry J⋅Markham, Merry Jennifer⋅Markham, Merry Jennifer⋅Markham, Merry J⋅Nephew, Kenneth P⋅Nephew, Kenneth⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Jueliger, Simone⋅Jueliger, Simone⋅Jueliger, Simone⋅Oganesian, Aram⋅Oganesian, Aram⋅Oganesian, Aram⋅Naim, Sue⋅Naim, Sue⋅Naim, Sue⋅Naim, Sue⋅Naim, Sue⋅Su, Xiang Yao⋅Su, Xiang⋅Su, Xiang Yao⋅Keer, Harold⋅Keer, Harold⋅Keer, Harold⋅Keer, Harold⋅Keer, Harold⋅Azab, Mohammad⋅Azab, Mohammad⋅Azab, Mohammad⋅Fleming, Gini⋅Fleming, Gini F⋅Fleming, Gini F⋅Fleming, Gini F and Fleming, Gini FClinical cancer research : an official journal of the American Association for Cancer Research, vol. 24, (no. 10), pp. 2293, 20180515.
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Changes in mRNA/protein expression and signaling pathways in in vivo passaged mouse ovarian cancer cells.Cai, Qingchun⋅Cai, Qingchun⋅Cai, Qingchun⋅Fan, Qipeng⋅Fan, Qipeng⋅Fan, Qipeng⋅Buechlein, Aaron⋅Buechlein, Aaron⋅Buechlein, Aaron⋅Miller, David⋅Miller, David⋅Miller, David⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Xu, Yan⋅Xu, Yan and Xu, YanPloS one, vol. 13, (no. 6), pp. e0197404, 2018.
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Epigenetic Crosstalk between the Tumor Microenvironment and Ovarian Cancer Cells: A Therapeutic Road Less Traveled.Klymenko, Yuliya and Nephew, Kenneth PCancers, vol. 10, (no. 9), August 30, 2018.
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Epigenetic Targeting of Adipocytes Inhibits High-Grade Serous Ovarian Cancer Cell Migration and InvasionTang, Jessica⋅J, Tang⋅N, Pulliam⋅Pulliam, Nicholas⋅A, Özeş⋅Özeş, Ali⋅Buechlein, Aaron⋅A, Buechlein⋅Ding, Ning⋅N, Ding⋅H, Keer⋅Keer, Harold⋅Rusch, Doug⋅D, Rusch⋅O'Hagan, Heather⋅H, O’Hagan⋅Stack, M Sharon⋅MS, Stack⋅KP, Nephew and Nephew, Kenneth PMolecular cancer research : MCR, vol. 16, (no. 8), pp. 1240, 2018-08-00.
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IL-6 mediates platinum-induced enrichment of ovarian cancer stem cellsWang, Yinu⋅Wang, Yinu⋅Wang, Yinu⋅Wang, Y.⋅Wang, Yinu⋅Zong, Xingyue⋅Zong, Xingyue⋅Zong, Xingyue⋅Zong, Xingyue⋅Zong, X.⋅Mitra, S.⋅Mitra, Sumegha⋅Mitra, Sumegha⋅Mitra, Sumegha⋅Mitra, Sumegha⋅Mitra, Anirban Kumar⋅Mitra, Anirban Kumar⋅Mitra, Anirban Kumar⋅Mitra, Anirban Kumar⋅Mitra, A.K.⋅Matei, Daniela⋅Matei, Daniela⋅Matei, Daniela⋅Matei, D.⋅Matei, Daniela⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, K.P. and Nephew, Kenneth PJCI insight, vol. 3, (no. 23), 2018-Dec-06.
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Incorporating DNA Methyltransferase Inhibitors (DNMTis) in the Treatment of Genitourinary Malignancies: A Systematic ReviewChovanec, Michal⋅Taza, Fadi⋅Kalra, Maitri⋅Hahn, Noah⋅Nephew, Kenneth⋅Spinella, Michael and Albany, CostantineTargeted Oncology, vol. 13, (no. 1), pp. 60, 20180200.
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Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activityÖzeş, Ali R⋅Özeş, Ali⋅Pulliam, Nick⋅Pulliam, Nick⋅Ertosun, Mustafa G⋅Ertosun, Mustafa⋅Yılmaz, Özlem⋅Yılmaz, Özlem⋅Tang, Jessica⋅Tang, Jessica⋅Çopuroğlu, Ece⋅Çopuroğlu, Ece⋅Matei, Daniela⋅Matei, Daniela⋅Özeş, Osman⋅Özeş, Osman N⋅Nephew, Kenneth P and Nephew, KennethOncogene, vol. 37, (no. 26), pp. 3589-3600, Jun 2018.
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Safety and tolerability of guadecitabine (SGI-110) plus cisplatin in patients (pts) with platinum-refractory germ cell tumors (GCT): Preliminary results from an open label phase 1b studyHashemi-Sadraei, Neda⋅Hashemi-Sadraei, Neda⋅Hashemi-Sadraei, Neda⋅Einhorn, Lawrence H⋅Einhorn, Lawrence H⋅Einhorn, Lawrence H⋅Perkins, Susan⋅Perkins, Susan⋅Perkins, Susan⋅Spinella, Michael J⋅Spinella, Michael J⋅Spinella, Michael J⋅Fang, Fang⋅Fang, Fang⋅Fang, Fang⋅Hanna, Nasser H⋅Hanna, Nasser H⋅Hanna, Nasser H⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Albany, Costantine⋅Albany, Costantine and Albany, CostantineJournal of Clinical Oncology, vol. 36, (no. 15_suppl), pp. e16545, 2018-05-20.
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2017
Abstract 4347: Epigenetic targeting of DNMT1 in adipocytes inhibits high-grade serous ovarian cancer cell migration and invasion through TIMP3 upregulationTang, Jessica⋅Fang, Fang⋅Buechlein, Aaron⋅Taverna, Pietro and Nephew, Kenneth PCancer Research, vol. 77, (no. 13 Supplement), pp. 4347, 2017-07-01.
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Abstract 4675: Novel combination therapy of DNA methyltransferase inhibitor guadecitabine (SGI-110) and PARP inhibitor talazoparib (BMN-673) for BRCA-proficient high-grade serous ovarian cancerPulliam, Nicholas⋅Taverna, Pietro⋅Lyons, John and Nephew, Kenneth PCancer Research, vol. 77, (no. 13 Supplement), pp. 4675, 2017-07-01.
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Complete Transcriptome RNA-SeqMiller, David F B⋅Yan, Pearlly⋅Fang, Fang⋅Buechlein, Aaron⋅Kroll, Karl⋅Frankhouser, David⋅Stump, Cameron⋅Stump, Paige⋅Ford, James B⋅Tang, Haixu⋅Michaels, Scott⋅Matei, Daniela⋅Huang, Tim H⋅Chien, Jeremy⋅Liu, Yunlong⋅Rusch, Douglas B and Nephew, Kenneth PMethods in molecular biology (Clifton, N.J.), vol. 1513, pp. 162, 2017-00-00.
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Complete Transcriptome RNA-SeqMiller, David F B⋅Yan, Pearlly⋅Fang, Fang⋅Buechlein, Aaron⋅Kroll, Karl⋅Frankhouser, David⋅Stump, Cameron⋅Stump, Paige⋅Ford, James B⋅Tang, Haixu⋅Michaels, Scott⋅Matei, Daniela⋅Huang, Tim H⋅Chien, Jeremy⋅Liu, Yunlong⋅Rusch, Douglas B and Nephew, Kenneth PMethods in molecular biology (Clifton, N.J.), vol. 1513, pp. 141, 2017-00-00.
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Complete Transcriptome RNA-SeqMiller, David F B⋅Yan, Pearlly⋅Fang, Fang⋅Buechlein, Aaron⋅Kroll, Karl⋅Frankhouser, David⋅Stump, Cameron⋅Stump, Paige⋅Ford, James B⋅Tang, Haixu⋅Michaels, Scott⋅Matei, Daniela⋅Huang, Tim H⋅Chien, Jeremy⋅Liu, Yunlong⋅Rusch, Douglas B and Nephew, Kenneth PMethods in molecular biology (Clifton, N.J.), vol. 1513, pp. 141, 2017-00-00.
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Complete Transcriptome RNA-Seq.Miller, David F B⋅Yan, Pearlly⋅Fang, Fang⋅Buechlein, Aaron⋅Kroll, Karl⋅Frankhouser, David⋅Stump, Cameron⋅Stump, Paige⋅Ford, James B⋅Tang, Haixu⋅Michaels, Scott⋅Matei, Daniela⋅Huang, Tim H⋅Chien, Jeremy⋅Liu, Yunlong⋅Rusch, Douglas B and Nephew, Kenneth PMethods in molecular biology (Clifton, N.J.), vol. 1513, pp. 141-162, 2017.
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Genomic and Epigenomic Signatures in Ovarian Cancer Associated with Re-sensitization to Platinum Drugs.Fang, Fang⋅Fang, Fang⋅Fang, Fang⋅Fang, Fang⋅Cardenas, Horacio⋅Cardenas, Horacio⋅Cardenas, Horacio⋅Cardenas, Horacio⋅Huang, Hao⋅Huang, Hao⋅Huang, Hao⋅Huang, Hao⋅Jiang, Guanglong⋅Jiang, Guanglong⋅Perkins, Susan M⋅Perkins, Susan M⋅Perkins, Susan M⋅Perkins, Susan M⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Zhang, Chi⋅Keer, Harold N⋅Keer, Harold N⋅Keer, Harold N⋅Keer, Harold N⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Matei, Daniela⋅Matei, Daniela⋅Matei, Daniela and Matei, DanielaCancer research, December 11, 2017.
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Moving forward with actionable therapeutic targets and opportunities in endometrial cancer: NCI clinical trials planning meeting report on identifying key genes and molecular pathways for targeted endometrial cancer trialsMacKay, Helen J⋅Levine, Douglas A⋅Bae-Jump, Victoria L⋅Bell, Daphne W⋅McAlpine, Jessica N⋅Santin, Alessandro⋅Fleming, Gini F⋅Mutch, David G⋅Nephew, Kenneth P⋅Wentzensen, Nicolas⋅Goodfellow, Paul J⋅Dorigo, Oliver⋅Nijman, Hans W⋅Broaddus, Russell and Kohn, Elise COncotarget, vol. 8, (no. 48), pp. 84594, 2017-Oct-13.
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The novel ZIP4 regulation and its role in ovarian cancerFan, Qipeng⋅Cai, Qingchun⋅Li, Pengfei⋅Wang, Wenyan⋅Wang, Jing⋅Gerry, Emily⋅Wang, Tian-Li⋅Shih, Ie-Ming⋅Nephew, Kenneth P and Xu, YanOncotarget, vol. 8, (no. 52), pp. 90107, 2017-Oct-27.
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Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancerÖzeş, Ali⋅Wang, Yinu⋅Zong, Xingyue⋅Fang, Fang⋅Pilrose, Jay and Nephew, KennethScientific Reports (Nature Publisher Group), vol. 7, pp. 1-11, Apr 2017.
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2016
Abstract 1980: Long-range regulation of HOTAIR identifies novel biomarkers of breast cancer outcome and suggests a role in genome instabilityMilevskiy, Michael J⋅Al-Ejeh, Fares⋅Saunus, Jodi M⋅Northwood, Korinne S⋅McCart-Reed, Amy E⋅Dray, Eloise⋅Nephew, Kenneth⋅Bailey, Peter J⋅Betts, Joshua A⋅Stone, Andrew⋅Gee, Julia M W⋅Shewan, Annette M⋅French, Juliet D⋅Edwards, Stacey L⋅Clark, Susan J⋅Lakhani, Sunil R and Brown, Melissa ACancer Research, vol. 76, (no. 14 Supplement), pp. 1980, 2016-07-15.
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Abstract 3789: Targeting cholesterol biosynthesis pathway to inhibit growth of drug resistant ovarian cancer cellsLiang, Yayun⋅Aebi, Johannes⋅Nephew, Kenneth and Hyder, Salman MCancer Research, vol. 76, (no. 14 Supplement), pp. 3789, 2016-07-15.
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