32 Publications (Page 1 of 2)
2020
Phenotypic Screening of Chemical Libraries Enriched by Molecular Docking to Multiple Targets Selected from Glioblastoma Genomic Data
Xu, David⋅Xu, David⋅Xu, David⋅Xu, David⋅Xu, David⋅Xu, David⋅Xu, David⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Sishtla, Kamakshi⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Liu, Sheng⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Wan, Jun⋅Aryal, Uma K⋅Aryal, Uma K⋅Aryal, Uma K⋅Aryal, Uma K⋅Aryal, Uma K⋅Aryal, Uma K⋅Aryal, Uma K⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Lee, Jonathan A⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Pollok, Karen⋅Pollok, Karen⋅Pollok, Karen⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen⋅Pollok, Karen⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O and Meroueh, Samy O
ACS chemical biology, 2020-Apr-03. | Journal Article
2019
Identification of Specific Lysines and Arginines That Mediate Angiomotin Membrane Association
Hall, Le'Celia⋅Hall, Le'Celia⋅Donovan, Emily⋅Donovan, Emily⋅Araya, Michael⋅Araya, Michael⋅Idowa, Eniola⋅Idowa, Eniola⋅Jiminez-Segovia, Ilse⋅Jiminez-Segovia, Ilse⋅Folck, Anthony⋅Folck, Anthony⋅Wells, Clark D⋅Wells, Clark D⋅Kimble Hill, Ann C and Kimble-Hill, Ann C
ACS omega, vol. 4, (no. 4), pp. 6736, 2019-Apr-30. | Journal Article
 
Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEADâ‹…Yap Protein-Protein Interaction
Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Bum-Erdene, Khuchtumur⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Zhou, Donghui⋅Gonzalez-Gutierrez, Giovanni⋅Gonzalez-Gutierrez, Giovanni⋅Gonzalez-Gutierrez, Giovanni⋅Gonzalez-Gutierrez, Giovanni⋅Ghozayel, Mona K⋅Ghozayel, Mona K⋅Ghozayel, Mona K⋅Ghozayel, Mona K⋅Si, Yubing⋅Si, Yubing⋅Si, Yubing⋅Si, Yubing⋅Xu, David⋅Xu, David⋅Xu, David⋅Xu, David⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Corson, Timothy W⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O and Meroueh, Samy O
Cell Chemical Biology, vol. 26, (no. 3), pp. 389.e13, 2019-03-00. | Journal Article
2014
Primary cilia signaling mediates intraocular pressure sensation.
Luo, Na⋅Luo, Na⋅Conwell, Michael D⋅Conwell, Michael D⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Kettenhofen, Christine Insinna⋅Kettenhofen, Christine I⋅Westlake, Christopher J⋅Westlake, Christopher J⋅Cantor, Louis B⋅Cantor, Louis B⋅Wells, Clark D⋅Wells, Clark D⋅Weinreb, Robert N⋅Weinreb, Robert N⋅Corson, Timothy W⋅Corson, Timothy W⋅Spandau, Dan F⋅Spandau, Dan F⋅Joos, Karen M⋅Joos, Karen M⋅Iomini, Carlo⋅Iomini, Carlo⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅Sun, Yang and Sun, Yang
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 35), pp. 12871-6, 2014/Sep/2. | Journal Article
 
The Role of Phosphoinositol Lipids in Amot Membrane Association
Kimble Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Johnson, Merrell⋅Johnson, Merrell⋅Johnson, Merrell⋅Johnson, Merrell⋅Firestone, Millicent A⋅Firestone, Millicent A⋅Firestone, Millicent A⋅Firestone, Millicent A⋅Petrache, Horia⋅Petrache, Horia⋅Petrache, Horia⋅Petrache, Horia⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Seifert, Soenke⋅Seifert, Soenke⋅Seifert, Soenke and Seifert, Soenke
Biophysical Journal, vol. 106, (no. 2), pp. 507a, 2014-01-28. | Journal Article
 
Toward Understanding the Role of Amot80 Lipid Binding in Cellular Proliferation and Migration
Donovan, Emily L⋅Donovan, Emily L⋅Donovan, Emily L⋅Kimble Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Wells, Clark D⋅Wells, Clark D and Wells, Clark D
Biophysical Journal, vol. 106, (no. 2), pp. 303a, 2014-01-28. | Journal Article
2013
Amot130 adapts atrophin-1 interacting protein 4 to inhibit yes-associated protein signaling and cell growth.
Adler, Jacob J⋅Heller, Brigitte L⋅Bringman, Lauren R⋅Ranahan, William⋅Cocklin, Ross R⋅Goebl, Mark G⋅Oh, Misook⋅Lim, Hyun Suk⋅Ingham, Robert and Wells, Clark D
The Journal of biological chemistry, vol. 288, (no. 21), pp. 15181-93, 2013/May/24. | Journal Article
 
Day as a Pathologist: Utilization of Technology to Guide Students in Exploring Careers in Breast Cancer Pathology
Adler, Jacob⋅Adler, Jacob⋅Judd, Mariah⋅Judd, Mariah⋅Bringman, Lauren⋅Bringman, Lauren⋅Wells, Clark⋅Wells, Clark⋅Marrs, Kathleen and Marrs, Kathleen
The American Biology Teacher, vol. 75, (no. 8), pp. 565, 2013. | Journal Article
 
LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, H. B⋅Babcock, J. T⋅Wells, Clark D and Quilliam, Lawrence A
Oncogene, vol. 32, (no. 35), pp. 4100-9, Aug 29, 2013. | Journal Article
 
Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases
Adler, Jacob⋅Adler, Jacob J⋅Adler, Jacob J⋅Johnson, Derrick⋅Johnson, Derrick E⋅Johnson, Derrick E⋅Heller, Brigitte L⋅Heller, Brigitte L⋅Heller, Brigitte⋅Bringman, Lauren R⋅Bringman, Lauren⋅Bringman, Lauren R⋅Ranahan, William P⋅Ranahan, William⋅Ranahan, William⋅Conwell, Michael⋅Conwell, Michael D⋅Conwell, Michael D⋅Sun, Yang⋅Sun, Yang⋅Sun, Yang⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Wells, Clark⋅Wells, Clark D and Wells, Clark D
Proceedings of the National Academy of Sciences of the United States of America, vol. 110, (no. 43), Oct 22, 2013. | Journal Article
 
Toward Understanding the Role of Angiomotin Lipid Binding in Cellular Proliferation and Migration
Kimble-Hill, Ann C⋅Kimble-Hill, Ann C⋅Kimble Hill, Ann C⋅Jimenez-Segovia, Ilse⋅Jimenez-Segovia, Ilse⋅Jimenez-Segovia, Ilse⋅Firestone, Millicent A⋅Firestone, Millicent A⋅Firestone, Millicent A⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Wells, Clark D⋅Wells, Clark D and Wells, Clark D
Biophysical Journal, vol. 104, (no. 2), pp. 594a, 2013-01-29. | Journal Article
2012
Abstract LB-29: LKB1 tumor suppressor regulates AMP kinase/mTOR-independent cell growth and proliferation via the phosphorylation of Yap
Nguyen, Hoa B⋅Nguyen, Hoa B⋅Babcock, Justin T⋅Babcock, Justin T⋅Wells, Clark D⋅Wells, Clark D⋅Quilliam, Lawrence A and Quilliam, Lawrence A
Cancer Research, vol. 72, (no. 8 Supplement), pp. LB-29, 2012-04-15. | Journal Article
 
OCRL localizes to the primary cilium: a new role for cilia in Lowe syndrome.
Luo, Na⋅Luo, Na⋅West, Callah C⋅West, Callah C⋅Murga-Zamalloa, Carlos A⋅Murga-Zamalloa, Carlos A⋅Sun, Lou⋅Sun, Lou⋅Anderson, Ryan M⋅Anderson, Ryan M⋅Wells, Clark D⋅Wells, Clark D⋅Weinreb, Robert N⋅Weinreb, Robert N⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Khanna, Hemant⋅Khanna, Hemant⋅Sun, Yang and Sun, Yang
Human molecular genetics, vol. 21, (no. 15), pp. 3333-44, 2012/Aug/1. | Journal Article
2011
OpenFreezer: a reagent information management software system.
Olhovsky, Marina⋅Williton, Kelly⋅Dai, Anna Y⋅Pasculescu, Adrian⋅Lee, John P⋅Goudreault, Marilyn⋅Wells, Clark D⋅Park, Jin G⋅Gingras, Anne Claude⋅Linding, Rune⋅Pawson, Anthony J and Colwill, Karen
Nature methods, vol. 8, (no. 8), pp. 612-3, 2011/Aug. | Journal Article
 
PRL-1 Protein Promotes ERK1/2 and RhoA Protein Activation through a Non-canonical Interaction with the Src Homology 3 Domain of p115 Rho GTPase-activating Protein
Bai, Yunpeng⋅Bai, Yunpeng⋅Bai, Yunpeng⋅Luo, Yong⋅Luo, Yong⋅Luo, Yong⋅Liu, Sijiu⋅Liu, Sijiu⋅Liu, Sijiu⋅Zhang, Lujuan⋅Zhang, Lujuan⋅Zhang, Lujuan⋅Shen, Kui⋅Shen, Kui⋅Shen, Kui⋅Dong, Yuanshu⋅Dong, Yuanshu⋅Dong, Yuanshu⋅Walls, Chad D⋅Walls, Chad D⋅Walls, Chad D.⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A.⋅Quilliam, Lawrence A⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D.⋅Cao, Youjia⋅Cao, Youjia⋅Cao, Youjia⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin and Zhang, Z. F
The Journal of biological chemistry, vol. 286, (no. 49), pp. 42324, 2011-Dec-09. | Journal Article
 
Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1
Jiang, Sixin⋅Jiang, Sixin⋅Jiang, Sixin⋅Wells, Clark D⋅Wells, Clark D⋅Wells, Clark D⋅Roach, Peter J⋅Roach, Peter J and Roach, Peter J
Biochemical and Biophysical Research Communications, vol. 413, (no. 3), pp. 425, 2011. | Journal Article
 
The adaptor protein AMOT promotes the proliferation of mammary epithelial cells via the prolonged activation of the extracellular signal-regulated kinases.
Ranahan, William⋅Han, Zhang⋅Smith-Kinnaman, Whitney⋅Nabinger, Sarah C⋅Heller, Brigitte⋅Herbert, Britney-Shea⋅Chan, Rebecca and Wells, Clark D
Cancer research, vol. 71, (no. 6), pp. 2203-11, 2011/Mar/15. | Journal Article
2010
Amot Recognizes a Juxtanuclear Endocytic Recycling Compartment via a Novel Lipid Binding Domain.
Heller, Brigitte⋅Heller, Brigitte⋅Adu-Gyamfi, Emmanuel⋅Adu-Gyamfi, Emmanuel⋅Smith-Kinnaman, Whitney⋅Smith-Kinnaman, Whitney⋅Babbey, Cliff⋅Babbey, Cliff⋅Vora, Mohsin⋅Vora, Mohsin⋅Xue, Yi⋅Xue, Yi⋅Bittman, Robert⋅Bittman, Robert⋅Stahelin, Robert V.⋅Stahelin, Robert V⋅Wells, Clark D. and Wells, Clark D
Journal of biological chemistry., vol. 285, (no. 16), pp. 12308-12320, 2010. | Journal Article
2009
Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation.
Meiri, David⋅Greeve, Melissa A⋅Brunet, Andrea⋅Finan, Dina⋅Wells, Clark D⋅LaRose, Jose and Rottapel, Robert
Molecular and cellular biology, vol. 29, (no. 21), pp. 5963-73, 2009/Nov. | Journal Article
2006
A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells.
Wells, Clark D⋅Fawcett,, James⋅Traweger, Andreas⋅Yamanaka, Yojiro⋅Goudreault, Marilyn⋅Elder, Kelly⋅Kulkarni, Sarang⋅Gish, Gerald⋅Virag, Cristina⋅Lim, Caesar⋅Colwill, Karen⋅Starostine, Andrei⋅Metalnikov, Pavel and Pawson, Tony
Cell, vol. 125, (no. 3), pp. 535-48, 2006/May/5. | Journal Article
 
Modification of the Creator recombination system for proteomics applications - improved expression by addition of splice sites
Colwill, Karen⋅Wells, Clark D⋅Elder, Kelly⋅Goudreault, Marilyn⋅Hersi, Kadija⋅Kulkarni, Sarang⋅Hardy, W. R⋅Pawson, Tony and Morin, Gregg B
BMC Biotechnology, vol. 6, (no. 1), 2006. | Journal Article
 
Modification of the Creator recombination system for proteomics applications--improved expression by addition of splice sites.
Colwill, Karen⋅Wells, Clark D⋅Elder, Kelly⋅Goudreault, Marilyn⋅Hersi, Kadija⋅Kulkarni, Sarang⋅Hardy, W R⋅Pawson, Tony and Morin, Gregg B
BMC biotechnology, vol. 6, pp. 13, 2006. | Journal Article
2005
The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis
Bakal, Christopher J⋅Finan, Dina⋅LaRose, Jose⋅Wells, Clark D⋅Gish, Gerald⋅Kulkarni, Sarang⋅DeSepulveda, Paulo⋅Wilde, Andrew and Rottapel, Robert
Proceedings of the National Academy of Sciences, USA, vol. 102, (no. 27), pp. 9529-9534, 2005. | Journal Article
2004
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
Jin, Jing⋅Smith, F D⋅Stark, Chris⋅Wells, Clark D⋅Fawcett, J.P.⋅Fawcett,, James⋅Kulkarni, Sarang⋅Metalnikov, Pavel⋅O'Donnell, P.⋅O'Donnell, Paul⋅Taylor, Paul⋅Taylor, Lorne⋅Zougman, Alexandre⋅Woodgett, James R⋅Langeberg, Lorene K⋅Scott, John D and Pawson, Anthony J
Current biology : CB, vol. 14, (no. 16), pp. 1436-50, 2004/Aug/24. | Journal Article
2003
Mapping the Galpha13 binding interface of the rgRGS domain of p115RhoGEF.
Chen, Zhe⋅Chen, Zhe⋅Singer, William D⋅Singer, William D⋅Wells, Clark D⋅Wells, Clark D⋅Sprang, Stephen R⋅Sprang, Stephen R⋅Sternweis, Paul C and Sternweis, Paul C
The Journal of biological chemistry, vol. 278, (no. 11), pp. 9912-9, 2003/Mar/14. | Journal Article