217 Publications (Page 4 of 9)
2013
IGF-1R modulation of acute GH-induced STAT5 signaling: role of protein tyrosine phosphatase activity.
Gan, Yujun⋅Gan, Yujun⋅Zhang, Yue⋅Zhang, Yue⋅Buckels, Ashiya⋅Buckels, Ashiya⋅Paterson, Andrew J⋅Paterson, Andrew J⋅Jiang, Jing⋅Jiang, Jing⋅Clemens, Thomas L⋅Clemens, Thomas L⋅Zhang, Z. F⋅Zhang, Zhong-Yin⋅Du, Keyong⋅Du, Keyong⋅Chang, Yingzi⋅Chang, Yingzi⋅Frank, Stuart J and Frank, Stuart J
Molecular endocrinology (Baltimore, Md.), vol. 27, (no. 11), pp. 1969-79, 2013/Nov. | Journal Article
 
Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1.
Dumaual, Carmen M⋅Dumaual, Carmen M⋅Steere, Boyd A⋅Steere, Boyd A⋅Walls, Chad D⋅Walls, Chad D⋅Wang, Mu⋅Wang, Mu⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Randall, Stephen K and Randall, Stephen K
PloS one, vol. 8, (no. 9), pp. e72977, 2013. | Journal Article
 
Protein tyrosine phosphatase 1B regulates pyruvate kinase M2 tyrosine phosphorylation.
Bettaieb, Ahmed⋅Bettaieb, Ahmed⋅Bakke, Jesse⋅Bakke, Jesse⋅Nagata, Naoto⋅Nagata, Naoto⋅Matsuo, Kosuke⋅Matsuo, Kosuke⋅Xi, Yannan⋅Xi, Yannan⋅Liu, Siming⋅Liu, Siming⋅AbouBechara, Daniel⋅AbouBechara, Daniel⋅Aboubechara, Daniel⋅Melhem, Ramzi⋅Melhem, Ramzi⋅Stanhope, Kimber L⋅Stanhope, Kimber⋅Cummings, Bethany⋅Cummings, Bethany⋅Graham, James⋅Graham, James⋅Bremer, Andrew⋅Bremer, Andrew⋅Zhang, Sheng⋅Zhang, Sheng⋅Lyssiotis, Costas A⋅Lyssiotis, Costas A⋅Zhang, Z. F⋅Zhang, Zhong-Yin⋅Cantley, Lewis C⋅Cantley, Lewis C⋅Havel, Peter J⋅Havel, Peter J⋅Haj, Fawaz G and Haj, Fawaz G
The Journal of biological chemistry, vol. 288, (no. 24), pp. 17360-71, 2013/Jun/14. | Journal Article
 
Redox regulation of protein tyrosine phosphatase activity by hydroxyl radical.
Meng, Fan-Guo and Zhang, Z. F
Biochimica et biophysica acta, vol. 1834, (no. 1), pp. 464-9, 2013/Jan. | Journal Article
 
Small molecule tools for functional interrogation of protein tyrosine phosphatases
He, Rongjun⋅Zeng, Li-Fan⋅He, Yantao⋅Zhang, Sheng and Zhang, Zhong-Yin
The FEBS Journal, vol. 280, (no. 2), pp. 731-750, Jan 2013. | Journal Article
 
Structural and mechanistic insights into LEOPARD syndrome-associated SHP2 mutations.
Yu, Zhi-Hong⋅Xu, Jie⋅Walls, Chad D⋅Chen, Lan⋅Zhang, Sheng⋅Zhang, Ruoyu⋅Wu, Li⋅Wang, Lina⋅Liu, Sijiu and Zhang, Z. F
The Journal of biological chemistry, vol. 288, (no. 15), pp. 10472-82, 2013/Apr/12. | Journal Article
 
Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma.
Xu, Jie⋅Zeng, Li-Fan⋅Shen, Weihua⋅Turchi, John J and Zhang, Z. F
Biochemical and biophysical research communications, vol. 439, (no. 4), pp. 586-90, 2013/Oct/4. | Journal Article
2012
A combinatorial strategy for the acquisition of potent and specific protein tyrosine phosphatase inhibitors.
Zhang, Sheng⋅Chen, Lan⋅Lawrence, David S and Zhang, Z. F
Methods in molecular biology (Clifton, N.J.), vol. 928, pp. 53-65, 2012. | Journal Article
 
A continuous spectrophotometric assay for mitogen-activated protein kinase kinases.
Zheng, Li-Sha⋅Zhang, Yuan-Yuan⋅Wu, Jia-Wei⋅Wu, Zhenguo⋅Zhang, Z. F and Wang, Zhi-Xin
Analytical biochemistry, vol. 421, (no. 1), pp. 191-7, 2012/Feb/1. | Journal Article
 
A highly selective and potent PTP-MEG2 inhibitor with therapeutic potential for type 2 diabetes.
Zhang, Sheng⋅Liu, Sijiu⋅Tao, Rongya⋅Wei, Dan⋅Chen, Lan⋅Shen, Weihua⋅Yu, Zhi-Hong⋅Wang, Lina⋅Jones, David R⋅Dong, Xiaocheng C and Zhang, Z. F
Journal of the American Chemical Society, vol. 134, (no. 43), pp. 18116-24, 2012/Oct/31. | Journal Article
 
Akt2 inhibits the activation of NFAT in lymphocytes by modulating calcium release from intracellular stores
Martin, V.A.⋅Martin, Victoria A⋅Wang, W.-H.⋅Wang, Wen-Horng⋅Lipchik, A.M.⋅Lipchik, Andrew M⋅Parker, Laurie L⋅Parker, L.L.⋅He, Yantao⋅He, Y.⋅Zhang, Sheng⋅Zhang, S.⋅Zhang, Zhong-Yin⋅Zhang, Z.-Y.⋅Geahlen, R.L. and Geahlen, Robert L
Cellular Signalling, vol. 24, (no. 5), pp. 1064-1073, 2012. | Journal Article
 
Bicyclic benzofuran and indole-based salicylic acids as protein tyrosine phosphatase inhibitors.
He, Yantao⋅Zeng, Li-Fan⋅Yu, Zhi-Hong⋅He, Rongjun⋅Liu, Sijiu and Zhang, Z. F
Bioorganic & medicinal chemistry, vol. 20, (no. 6), pp. 1940-6, 2012/Mar/15. | Journal Article
 
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT.
Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅Sims, Emily⋅Sims, Emily⋅Sims, Emily⋅Sims, Emily⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Sharma, Namit⋅Sharma, Namit⋅Sharma, Namit⋅Sharma, Namit⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Li, Shuo⋅Li, Shuo⋅Li, Shuo⋅Li, Shuo⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Craig, Andrew W⋅Craig, Andrew W⋅Craig, Andrew W⋅Craig, Andrew W⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 13), pp. 2669-78, 2012/Sep/27. | Journal Article
 
SH2 domain-containing phosphatase 2 is a critical regulator of connective tissue mast cell survival and homeostasis in mice.
Sharma, Namit⋅Sharma, Namit⋅Kumar, Vijay⋅Kumar, Vijay⋅Everingham, Stephanie⋅Everingham, Stephanie⋅Mali, Raghuveer⋅Mali, Raghuveer S⋅Kapur, Reuben⋅Kapur, Reuben⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zhang, Z. F⋅Zhang, Zhong-Yin⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Hartmann, Karin⋅Hartmann, Karin⋅Roers, Axel⋅Roers, Axel⋅Craig, Andrew W and Craig, Andrew
Molecular and cellular biology, vol. 32, (no. 14), pp. 2653-63, 2012/Jul. | Journal Article
2011
Combination therapy of an inhibitor of group VIA phospholipase A2 with paclitaxel is highly effective in blocking ovarian cancer development.
Li, Hui⋅Zhao, Zhenwen⋅Antalis, Caryl⋅Zhao, Zhanzhong⋅Emerson, Robert⋅Wei, Gang⋅Zhang, Sheng⋅Zhang, Zhong-Yin and Xu, Yan
The American journal of pathology, vol. 179, (no. 1), pp. 452-461, July 2011. | Journal Article
 
Discovery of a novel series of inhibitors of lymphoid tyrosine phosphatase with activity in human T cells.
Stanford, Stephanie M⋅Stanford, Stephanie M⋅Krishnamurthy, Divya⋅Krishnamurthy, Divya⋅Falk, Matthew D⋅Falk, Matthew D⋅Messina, Rossella⋅Messina, Rossella⋅Debnath, Bikash⋅Debnath, Bikash⋅Li, Sheng⋅Li, Sheng⋅Liu, Tong⋅Liu, Tong⋅Kazemi, Roza⋅Kazemi, Roza⋅Dahl, Russell⋅Dahl, Russell⋅He, Yantao⋅He, Yantao⋅Yu, Xiao⋅Yu, Xiao⋅Chan, Andrew C⋅Chan, Andrew C⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Barrios, Amy M⋅Barrios, Amy M⋅Woods, Virgil L⋅Woods, Jr, Virgil L⋅Neamati, Nouri⋅Neamati, Nouri⋅Bottini, Nunzio and Bottini, Nunzio
Journal of medicinal chemistry, vol. 54, (no. 6), pp. 1640-54, 2011/Mar/24. | Journal Article
 
Hypervalent organochalcogenanes as inhibitors of protein tyrosine phosphatases.
Piovan, Leandro⋅Wu, Li⋅Zhang, Z. F and Andrade, Leandro H
Organic & biomolecular chemistry, vol. 9, (no. 5), pp. 1347-51, 2011/Mar/7. | Journal Article
 
SHP2 is a target of the immunosuppressant tautomycetin.
Liu, Sijiu⋅Yu, Zhihong⋅Yu, Xiao⋅Huang, Sheng-Xiong⋅Luo, Yinggang⋅Wu, Li⋅Shen, Weihua⋅Yang, Zhenyun⋅Wang, Lina⋅Gunawan, Andrea M⋅Chan, Rebecca J⋅Shen, Ben and Zhang, Z. F
Chemistry & biology, vol. 18, (no. 1), pp. 101-10, 2011/Jan/28. | Journal Article
 
Small molecule inhibitors of SHP2 tyrosine phosphatase discovered by virtual screening
Yu, Zhi-Hong⋅Chen, Lan⋅Wu, Li⋅Liu, Sijiu⋅Wang, Lina and Zhang, Zhong-Yin
Bioorganic and Medicinal Chemistry Letters, vol. 21, (no. 14), pp. 4238-4242, 2011. | Journal Article
 
Substrate specificity of lymphoid-specific tyrosine phosphatase (Lyp) and identification of Src kinase-associated protein of 55 kDa homolog (SKAP-HOM) as a Lyp substrate.
Yu, Xiao⋅Chen, Ming⋅Zhang, Sheng⋅Yu, Zhi-Hong⋅Sun, Jin-Peng⋅Wang, Lina⋅Liu, Sijiu⋅Imasaki, Tsuyoshi⋅Takagi, Yuichiro and Zhang, Z. F
The Journal of biological chemistry, vol. 286, (no. 35), pp. 30526-34, 2011/Sep/2. | Journal Article
 
TCPTP-deficiency in muscle does not alter insulin signalling and glucose homeostasis
Loh, K.⋅Loh, K.⋅Loh, Kim⋅Merry, TL⋅Merry, T.L.⋅Merry, Troy L⋅Galic, S.⋅Galic, S.⋅Galic, Sandra⋅Wu, BJ⋅Wu, Ben J⋅Wu, B.J.⋅Watt, Matthew J⋅Watt, Matthew J⋅Watt, M.J.⋅Zhang, S.⋅Zhang, S.⋅Zhang, Sheng⋅Zhang, Zhong-Yin⋅Zhang, Z-Y⋅Zhang, Z.-Y.⋅Neel, Benjamin G⋅Neel, B.G.⋅Neel, BG⋅Tiganis, Tony⋅Tiganis, Tony and Tiganis, T.
Diabetologia, vol. 55, (no. 2), pp. 478, 2011-11-29. | Journal Article
 
TNF-stimulated MAP kinase activation mediated by a Rho family GTPase signaling pathway
Kant, Shashi |⋅Swat, Wojciech A⋅Zhang, Sheng⋅Zhang, Zhong-Yin⋅Neel, Benjamin G⋅Flavell, Richard A and Davis, Roger
Genes & Development, vol. 25, (no. 19), pp. 2069-2078, 2011. | Journal Article
2010
Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects.
Long, S A⋅Cerosaletti, Karen⋅Bollyky, Paul⋅Tatum, Megan⋅Shilling, Heather⋅Zhang, Sheng⋅Zhang, Z. F⋅Pihoker, Catherine A⋅Sanda, Srinath⋅Greenbaum, Carla J and Buckner, Jane H
Diabetes, vol. 59, (no. 2), pp. 407-15, 2010/Feb. | Journal Article
 
Derivatives of Salicylic Acid as Inhibitors of YopH in Yersinia pestis
Huang, Zunnan⋅He, Yantao⋅Zhang, Xian⋅Gunawan, Andrea⋅Wu, Li⋅Zhang, Zhong-Yin and Wong, Chung F
Chemical Biology & Drug Design, vol. 76, (no. 2), pp. 85-99, 2010. | Journal Article
 
Double click reaction for the acquisition of a highly potent and selective mPTPB inhibitor.
He, Rongjun⋅Yu, Zhihong⋅He, Yantao⋅Zeng, Li-Fan⋅Xu, Jie⋅Wu, Li⋅Gunawan, Andrea M⋅Wang, Lina⋅Jiang, Zhong-Xing and Zhang, Z. F
ChemMedChem, vol. 5, (no. 12), pp. 2051-6, 2010/Dec/3. | Journal Article