217 Publications (Page 7 of 9)
2003
Mechanistic Studies on Protein Tyrosine PhosphatasesZhang, Z. F and Zhang, Zhong-YinProgress in Nucleic Acid Research and Molecular Biology, vol. 73, pp. 220, 2003.
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PTP1B inhibitors as potential therapeutics in the treatment of Type 2 diabetes and obesityZhang, Z. F⋅Zhang, Zhong-Yin⋅Lee, Seung-Yub and Lee, Seung-YubExpert Opinion on Investigational Drugs, vol. 12, (no. 2), pp. 233, 2003-00-00.
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Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells.Goldberg, Gary S.⋅Goldberg, Gary S⋅Alexander, David B.⋅Alexander, David B⋅Pellicena, Patricia⋅Pellicena, Patricia⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Tsuda, Hiroyuki⋅Tsuda, Hiroyuki⋅Miller, W. T and Miller, W. ToddThe Journal of biological chemistry, vol. 278, (no. 47), pp. 46533-40, 2003/Nov/21.
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Tripeptide inhibitors of Yersinia protein-tyrosine phosphataseLee, Kyeong⋅Lee, Kyeong⋅Gao, Yang⋅Gao, Yang⋅Yao, Zhu-Jun⋅Yao, Zhu-Jun⋅Phan, Jason⋅Phan, Jason⋅Wu, Li⋅Wu, Li⋅Liang, Jiao⋅Liang, Jiao⋅Waugh, David S⋅Waugh, David S⋅Zhang, Z. F⋅Zhang, Zhong-Yin⋅Burke, Terrence R and Burke, Terrence RBioorganic & Medicinal Chemistry Letters, vol. 13, (no. 15), pp. 2581, 2003.
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2002
Assays for protein-tyrosine phosphatases
McCain, Daniel F and Zhang, Zhong-Yin
Methods in enzymology, vol. 345, pp. 507, 2002-00-00. | Journal Article
Assays for protein-tyrosine phosphatases
McCain, Daniel F. and Zhang, Zhong-Yin
Methods in Enzymology, vol. 345, pp. 518, 2002. | Journal Article
Design and Characterization of an Improved Protein Tyrosine Phosphatase Substrate-Trapping MutantXie, Laiping⋅Xie, Laiping⋅Zhang, Yan-Ling⋅Zhang, Yan-Ling⋅Zhang, Z. F and Zhang, Zhong-YinBiochemistry, vol. 41, (no. 12), pp. 4039, 20020326.
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Environmental Effects on Phosphoryl Group Bonding Probed by Vibrational Spectroscopy: Implications for Understanding Phosphoryl Transfer and Enzymatic CatalysisCheng, Hu⋅Cheng, Hu⋅Nikolic-Hughes, Ivana⋅Nikolic-Hughes, Ivana⋅Wang, Jianghua H⋅Wang, Jianghua H⋅Deng, Hua⋅Deng, Hua⋅O'brien, Patrick J⋅O'Brien, Patrick J⋅Wu, Li⋅Wu, Li⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Herschlag, Daniel⋅Herschlag, Daniel⋅Callender, Robert and Callender, RobertJournal of the American Chemical Society, vol. 124, (no. 38), pp. 11306, 20020925.
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Modulation of protein kinase signaling by protein phosphatases and inhibitorsZhang, Z. F⋅Zhang, Zhong-Yin⋅Zhou, Bo⋅Zhou, Bo⋅Xie, Laiping and Xie, LaipingPharmacology and Therapeutics, vol. 93, (no. 2), pp. 317, 2002.
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Probing the Molecular Basis for Potent and Selective Protein-tyrosine Phosphatase 1B InhibitionGuo, Xiao-Ling⋅Guo, Xiao-Ling⋅Shen, Kui⋅Shen, Kui⋅Wang, Fang⋅Wang, Fang⋅Lawrence, David S⋅Lawrence, David⋅Zhang, Zhong-Yin and Zhang, Z. FJournal of Biological Chemistry, vol. 277, (no. 43), pp. 41022, 20021025.
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Probing the Phosphopeptide Specificities of Protein Tyrosine Phosphatases, SH2 and PTB Domains with Combinatorial Library MethodsVetter, Stefan⋅Vetter, Stefan W⋅Zhang, Zhong-Yin and Zhang, Z. FCurrent Protein & Peptide Science, vol. 3, (no. 4), pp. 397, 2002-August.
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PROTEIN TYROSINE PHOSPHATASES: Structure and Function, Substrate Specificity, and Inhibitor DevelopmentZhang, Z. F and Zhang, Zhong-YinAnnual review of pharmacology and toxicology, vol. 42, pp. 209, 2002-00-00.
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The Activity of the Extracellular Signal-regulated Kinase 2 Is Regulated by Differential Phosphorylation in the Activation LoopZhou, Bo⋅Zhou, Bo⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Biological Chemistry, vol. 277, (no. 16), pp. 13899, 20020419.
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The catalytic mechanism of Cdc25A phosphatase.McCain, Daniel F⋅Catrina, Irina E⋅Hengge, Alvan and Zhang, Z. FThe Journal of biological chemistry, vol. 277, (no. 13), pp. 11190-200, 2002/Mar/29.
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The Specificity of Extracellular Signal-regulated Kinase 2 Dephosphorylation by Protein PhosphatasesZhou, Bo⋅Zhou, Bo⋅Wang, Zhi-Xin⋅Wang, Zhi-Xin⋅Zhao, Yu⋅Zhao, Yu⋅Brautigan, David L⋅Brautigan, David⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Biological Chemistry, vol. 277, (no. 35), pp. 31825, 20020830.
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2001
Acquisition of a Specific and Potent PTP1B Inhibitor from a Novel Combinatorial Library and Screening ProcedureShen, Kui⋅Shen, Kui⋅Keng, Y F⋅Keng, Yen-Fang⋅Wu, L⋅Wu, Li⋅Guo, X L⋅Guo, Xiao-Ling⋅Lawrence, David S⋅Lawrence, David⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Biological Chemistry, vol. 276, (no. 50), pp. 47319, 20011214.
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Multiple Regions of MAP Kinase Phosphatase 3 Are Involved in Its Recognition and Activation by ERK2Zhou, B⋅Zhou, Bo⋅Wu, L⋅Wu, Li⋅Shen, K⋅Shen, Kui⋅Zhang, J⋅Zhang, Jialin⋅Lawrence, D S⋅Lawrence, David⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Biological Chemistry, vol. 276, (no. 9), pp. 6515, 20010302.
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Phospho-azatyrosine, a less effective protein-tyrosine phosphatase substrate than phosphotyrosineBurke, Terrence R⋅Burke, Terrence R⋅Yao, Z J⋅Yao, Zhu-Jun⋅Ye, B⋅Ye, Bin⋅Miyoshi, K⋅Miyoshi, Kengo⋅Otaka, A⋅Otaka, Akira⋅Wu, L⋅Wu, Li⋅Zhang, Z. F and Zhang, Zhong-YinBioorganic & Medicinal Chemistry Letters, vol. 11, (no. 10), pp. 1268, 2001.
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Protein tyrosine phosphatases: prospects for therapeuticsZhang, Z. F and Zhang, Zhong-YinCurrent Opinion in Chemical Biology, vol. 5, (no. 4), pp. 423, 2001-08-01.
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The Mechanism of Dephosphorylation of Extracellular Signal-regulated Kinase 2 by Mitogen-activated Protein Kinase Phosphatase 3Zhao, Y⋅Zhao, Yu⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Biological Chemistry, vol. 276, (no. 34), pp. 32391, 20010824.
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Utilization of a Peptide Lead for the Discovery of a Novel PTP1B-Binding MotifGao, Y⋅Gao, Yang⋅Voigt, J⋅Voigt, Johannes⋅Zhao, H⋅Zhao, He⋅Pais, G C⋅Pais, Godwin C. G⋅Zhang, X⋅Zhang, Xuechun⋅Wu, L⋅Wu, Li⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Burke, Terrence R and Burke, Terrence RJournal of Medicinal Chemistry, vol. 44, (no. 18), pp. 2878, 20010830.
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2000
Effects on General Acid Catalysis from Mutations of the Invariant Tryptophan and Arginine Residues in the Protein Tyrosine Phosphatase from YersiniaHoff, RH⋅Hoff, Richard H⋅Hengge, Alvan⋅Hengge, Alvan C⋅Wu, L.⋅Wu, Li⋅Keng, Yen-Fang⋅Keng, Y-F⋅Zhang, Zhong Yin and Zhang, Zhong-YinBiochemistry, vol. 39, (no. 1), pp. 54, 20000111.
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Inhibition of Protein Tyrosine Phosphatases by Low-Molecular-Weight S-Nitrosothiols and S-Nitrosylated Human Serum AlbuminMing Xian, et al.⋅Xian, Ming⋅Wang, Kun⋅Chen, Xinchao⋅Hou, Yongchun⋅McGill, Andrea⋅Chen, Xi⋅Zhou, Bo⋅Zhang, Zhong-Yin⋅Cheng, Jin-Pei⋅Wang, Peng George and Xian, MingBiochemical and Biophysical Research Communications, vol. 268, (no. 2), pp. 314, 2000-02-16.
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Structural Basis of Plasticity in Protein Tyrosine Phosphatase 1B Substrate RecognitionSarmiento, M⋅Sarmiento, Mauro⋅Puius, Yoram A⋅Puius, Yoram A⋅Vetter, Stefan W⋅Vetter, Stefan W⋅Keng, Y F⋅Keng, Yen-Fang⋅Wu, L⋅Wu, Li⋅Zhao, Yu⋅Zhao, Y⋅Lawrence, David S⋅Lawrence, D S⋅Almo, Steven C⋅Almo, Steven C⋅Zhang, Z. F and Zhang, Zhong-YinBiochemistry, vol. 39, (no. 28), pp. 8179, 20000718.
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Structure-Based Discovery of Small Molecule Inhibitors Targeted to Protein Tyrosine Phosphatase 1BSarmiento, Mauro⋅Sarmiento, M⋅Wu, L⋅Wu, Li⋅Keng, Yen-Fang⋅Keng, Y F⋅Song, L⋅Song, Li⋅Luo, Z⋅Luo, Zhaowen⋅Huang, Ziwei⋅Huang, Ziwei⋅Wu, G Z⋅Wu, Guo-Zhang⋅Yuan, A K⋅Yuan, Adam K⋅Zhang, Z. F and Zhang, Zhong-YinJournal of Medicinal Chemistry, vol. 43, (no. 2), pp. 155, 20000127.
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