217 Publications (Page 5 of 9)
2010
Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2).
Zhang, XianHe, YantaoLiu, SijiuYu, ZhihongJiang, Zhong-XingYang, ZhenyunDong, YuanshuNabinger, Sarah CWu, LiGunawan, Andrea MWang, LinaChan, Rebecca J and Zhang, Z. F
Journal of medicinal chemistry, vol. 53, (no. 6), pp. 2482-93, 2010/Mar/25. | Journal Article
2009
Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells.
Arias-Romero, Luis ESaha, SayantiVillamar-Cruz, OlgaYip, Shu-ChinEthier, Stephen PZhang, Z. F and Chernoff, Jonathan
Cancer research, vol. 69, (no. 11), pp. 4582-8, 2009/Jun/1. | Journal Article
 
Activity-based protein profiling of protein tyrosine phosphatases.
Walls, ChadZhou, Bo and Zhang, Z. F
Methods in molecular biology (Clifton, N.J.), vol. 519, pp. 417-29, 2009. | Journal Article
 
A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus.
OrrĂº, ValeriaTsai, Sophia JRueda, BlancaFiorillo, EdoardoStanford, Stephanie MDasgupta, JhimliHartiala, JaanaZhao, LeiOrtego-Centeno, NorbertoD'Alfonso, SandraArnett, Frank CArnett, Frank CWu, HuiWu, HuiGonzalez-Gay, Miguel ATsao, Betty PGonzalez-Gay, Miguel ATsao, Betty PPons-Estel, BernardoAlarcon-Riquelme, Marta EPons-Estel, BernardoAlarcon-Riquelme, Marta EHe, YantaoHe, YantaoZhang, Z. FZhang, Zhong-YinAllayee, HoomanChen, XiaojiangAllayee, HoomanChen, Xiaojiang SMartin, JavierMartin, JavierBottini, Nunzio and Bottini, Nunzio
Human molecular genetics, vol. 18, (no. 3), pp. 569-579, February 1, 2009. | Journal Article
 
Cutting edge: the PTPN22 allelic variant associated with autoimmunity impairs B cell signaling.
Arechiga, Adrian FHabib, TaniaHe, YantaoZhang, XianZhang, Z. FFunk, Andrew and Buckner, Jane H
Journal of immunology (Baltimore, Md. : 1950), vol. 182, (no. 6), pp. 3343-7, 2009/Mar/15. | Journal Article
 
PRL1 promotes cell migration and invasion by increasing MMP2 and MMP9 expression through Src and ERK1/2 pathways.
Luo, YongLiang, Fubo and Zhang, Z. F
Biochemistry, vol. 48, (no. 8), pp. 1838-46, 2009/Mar/3. | Journal Article
2008
A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells
Boivin, BenoitZhang, ShengArbiser, Jack LZhang, Zhong-Yin and Tonks, Nicholas K
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 29), Jul 22, 2008. | Journal Article
 
Aryl vinyl sulfonates and sulfones as active site-directed and mechanism-based probes for protein tyrosine phosphatases.
Liu, SijiuZhou, BoYang, HeyiHe, YantaoJiang, Zhong-XingKumar, SanjaiWu, Li and Zhang, Z. F
Journal of the American Chemical Society, vol. 130, (no. 26), pp. 8251-60, 2008/Jul/2. | Journal Article
 
Calpain 2 and PTP1B function in a novel pathway with Src to regulate invadopodia dynamics and breast cancer cell invasion
Cortesio, Christa LChan, Keefe TPerrin, Benjamin JBurton, Nicholas OZhang, ShengZhang, Zhong-Yin and Huttenlocher, Anna
The Journal of Cell Biology, vol. 180, (no. 5), Mar 2008. | Journal Article
 
Seleninate in Place of Phosphate: Irreversible Inhibition of Protein Tyrosine Phosphatases
Abdo, MohannadAbdo, MohannadLiu, SijiuLiu, SijiuZhou, BoZhou, BoWalls, Chad DWalls, Chad DWu, LiWu, LiKnapp, SpencerKnapp, SpencerZhang, Z. F and Zhang, Zhong-Yin
Journal of the American Chemical Society, vol. 130, (no. 40), pp. 13197, 20081008. | Journal Article
 
Targeting inactive enzyme conformation: aryl diketoacid derivatives as a new class of PTP1B inhibitors.
Liu, SijiuZeng, Li-FanWu, LiYu, XiaoXue, TingGunawan, Andrea MLong, Ya Qiu and Zhang, Z. F
Journal of the American Chemical Society, vol. 130, (no. 50), pp. 17075-84, 2008/Dec/17. | Journal Article
 
Translational Control of C-terminal Src Kinase (Csk) Expression by PRL3 Phosphatase
Liang, FuboLuo, YongDong, YuanshuWalls, Chad DLiang, JiaoJiang, Hao-YuanSanford, JeremyWek, Ronald and Zhang, Zhong-Yin
Journal of Biological Chemistry, vol. 283, (no. 16), pp. 10339-10346, 2008. | Journal Article
2007
An affinity-based fluorescence polarization assay for protein tyrosine phosphatases.
Zhang, ShengChen, LanKumar, SanjaiWu, LiLawrence, David S and Zhang, Z. F
Methods (San Diego, Calif.), vol. 42, (no. 3), pp. 261-7, 2007/Jul. | Journal Article
 
Application of hydrogen/deuterium exchange mass spectrometry to study protein tyrosine phosphatase dynamics, ligand binding, and substrate specificity.
Zhou, Bo and Zhang, Z. F
Methods (San Diego, Calif.), vol. 42, (no. 3), pp. 227-33, 2007/Jul. | Journal Article
 
Emerging new techniques for studying protein phosphatases
Zhang, Zhong-Yin and Zhang, Z. F
Methods, vol. 42, (no. 3), pp. 206, 2007. | Journal Article
 
Loop Dynamics and Ligand Binding Kinetics in the Reaction Catalyzed by the Yersinia Protein Tyrosine Phosphatase
Khajehpour, M.Wu, L.Liu, S.Zhadin, NickolayZhang, Zhong-Yin and Callender, Robert H
Biochemistry (Washington), vol. 46, (no. 14), pp. 4370-4378, 2007. | Journal Article
 
PRL3 Promotes Cell Invasion and Proliferation by Down-regulation of Csk Leading to Src Activation
Liang, FuboLiang, FuboLiang, JiaoLiang, JiaoWang, Wei-QingWang, Wei-QingSun, Jin-PengSun, Jin-PengUdho, EshwarUdho, EshwarZhang, Zhong Yin and Zhang, Zhong-Yin
Journal of Biological Chemistry, vol. 282, (no. 8), pp. 5419, 20070223. | Journal Article
 
Proteomic approaches to studying protein tyrosine phosphatases
Liang, FuboLiang, FuboKumar, SanjaiKumar, SanjaiZhang, Z. F and Zhang, Zhong-Yin
Molecular BioSystems, vol. 3, (no. 5), pp. 316, 20070426. | Journal Article
 
PTP1B as a drug target: recent developments in PTP1B inhibitor discovery
Zhang, ShengZhang, ShengZhang, Z. FZhang, Zhong-Yin and Zhang, Zhong-Yin
Drug Discovery Today, vol. 12, (no. 9), pp. 381, 2007. | Journal Article
 
Structural genomics of protein phosphatases
Almo, Steven CAlmo, Steven CAlmo, Steven CBonanno, Jeffrey BBonanno, Jeffrey BBonanno, Jeffrey BSauder, J MichaelSauder, J MichaelSauder, JMichaelEmtage, SpencerEmtage, SpencerEmtage, SpencerDilorenzo, Teresa PDi Lorenzo, Teresa PDilorenzo, Teresa PDilorenzo, Teresa PMalashkevich, VladimirMalashkevich, Vladimir NMalashkevich, VladimirWasserman, Steven RWasserman, Steven RWasserman, Steven RSwaminathan, SSwaminathan, S.Swaminathan, SEswaramoorthy, SubramaniamEswaramoorthy, SubramaniamEswaramoorthy, SubramaniamAgarwal, RakhiAgarwal, RakhiAgarwal, RakhiKumaran, DesiganKumaran, DesiganKumaran, DesiganMadegowda, MahendraMadegowda, MahendraMadegowda, MahendraRagumani, SugadevRagumani, SugadevRagumani, SugadevPatskovsky, Yury VPatskovsky, YuryPatskovsky, YuryAlvarado, JohnjeffAlvarado, JohnjeffAlvarado, JohnjeffRamagopal, Udupi ARamagopal, Udupi ARamagopal, Udupi AFaber-barata, JoanaFaber-Barata, JoanaFaber-Barata, JoanaFaber-Barata, JoanaChance, Mark RChance, Mark RChance, Mark RSali, AndrejSali, AndrejSali, AndrejFiser, AndrasFiser, AndrasFiser, AndrasZhang, Zhong-yinZhang, Zhong-yinZhang, Zhong-YinLawrence, David SLawrence, David SLawrence, David SBurley, Stephen KBurley, Stephen K and Burley, Stephen K
Journal of Structural and Functional Genomics, vol. 8, (no. 2-3), pp. 121-140, 2007. | Journal Article
 
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases
Yu, XiaoYu, XiaoSun, Jin-PengSun, Jin-PengHe, YantaoHe, YantaoGuo, XiaolingGuo, XiaolingLiu, SijiuLiu, SijiuZhou, BoZhou, BoHudmon, AndyHudmon, AndyZhang, Zhong-Yin and Zhang, Zhong-Yin
Proceedings of the National Academy of Sciences of the United States of America, vol. 104, (no. 50), Dec 11, 2007. | Journal Article
2006
Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: a mechanism of tamoxifen resistance.
Cui, YukunParra, IrmaZhang, MaoHilsenbeck, Susan GTsimelzon, AnnaFurukawa, ToruHorii, AkiraZhang, Z. FNicholson, Robert I and Fuqua, Suzanne A
Cancer research, vol. 66, (no. 11), pp. 5950-9, 2006/Jun/1. | Journal Article
 
Epidermal Growth Factor Receptor Overexpression Results in Increased Tumor Cell Motility In vivo Coordinately with Enhanced Intravasation and Metastasis
Xue, ChengsenXue, ChengsenWyckoff, JeffreyWyckoff, Jeffrey BLiang, FuboLiang, FuboSidani, MazenSidani, MazenViolini, StefaniaViolini, StefaniaTsai, Kun-LinTsai, Kun-LinZhang, Zhong YinZhang, Zhong-YinSahai, ErikSahai, ErikCondeelis, JohnCondeelis, John SSegall, Jeffrey E and Segall, Jeffrey
Cancer Research, vol. 66, (no. 1), pp. 192, 20060101. | Journal Article
 
Global Analysis of Protein Tyrosine Phosphatase Activity with Ultra-Sensitive Fluorescent Probes
Kumar, SanjaiKumar, SanjaiZhou, BoZhou, BoLiang, FuboLiang, FuboYang, HeyiYang, HeyiWang, Wei-QingWang, Wei-QingZhang, Z. F and Zhang, Zhong-Yin
Journal of Proteome Research, vol. 5, (no. 8), pp. 1905, 20060804. | Journal Article
 
Mapping ERK2-MKP3 binding interfaces by hydrogen/deuterium exchange mass spectrometry.
Zhou, BoZhang, JialinLiu, SijiuReddy, SharanyaWang, Fang and Zhang, Z. F
The Journal of biological chemistry, vol. 281, (no. 50), pp. 38834-44, 2006/Dec/15. | Journal Article