183 Publications (Page 4 of 8)
2011
Mapping the catechol binding site in dopamine D₁ receptors: synthesis and evaluation of two parallel series of bicyclic dopamine analogues.
Bonner, Lisa ALaban, UrosChemel, Benjamin RJuncosa, Jose ILill, Markus AWatts, Val J and Nichols, David E
ChemMedChem, vol. 6, (no. 6), pp. 1024-40, 2011/Jun/6. | Journal Article
 
Molecular and pharmacological characterization of two D(1)-like dopamine receptors in the Lyme disease vector, Ixodes scapularis.
Meyer, Jason MEjendal, Karin FWatts, Val J and Hill, Catherine
Insect biochemistry and molecular biology, vol. 41, (no. 8), pp. 563-71, 2011/Aug. | Journal Article
 
Molecular and pharmacological characterization of two D1-like dopamine receptors in the Lyme disease vector, Ixodes scapularis
Meyer, Jason MEjendal, Karin FWatts, Val J and Hill, Catherine
Insect Biochemistry and Molecular Biology, vol. 41, (no. 8), pp. 563-571, 2011. | Journal Article
 
Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues.
Cueva, Juan PGallardo-Godoy, AlejandraJuncosa, Jose IVidi, Pierre ALill, Markus AWatts, Val J and Nichols, David E
Journal of medicinal chemistry, vol. 54, (no. 15), pp. 5508-21, 2011/Aug/11. | Journal Article
2010
AGS3 blocks D2L dopamine receptor‐mediated heterologous sensitization of adenylyl cyclase 2
Conley, Jason Michael and Watts, Val J
The FASEB journal, vol. 24, (no. S1), pp. 587.5, April 2010. | Journal Article
 
Facile synthesis of octahydrobenzo[h]isoquinolines: novel and highly potent D1 dopamine agonists.
Bonner, Lisa AChemel, Benjamin RWatts, Val J and Nichols, David E
Bioorganic & medicinal chemistry, vol. 18, (no. 18), pp. 6763-70, 2010/Sep/15. | Journal Article
 
Facile synthesis of octahydrobenzo[h]isoquinolines: Novel and highly potent D sub(1) dopamine agonists
Bonner, Lisa AChemel, Benjamin RWatts, Val J and Nichols, David E
Bioorganic and Medicinal Chemistry, vol. 18, (no. 18), pp. 6763-6770, 2010. | Journal Article
 
Heterologous sensitization of human AC5: dependence on heterotrimeric G proteins
Ejendal, Karin F KSadana, RachnaVidi, Pierre‐AlexandreDessauer, Carmen W and Watts, Val J
The FASEB journal, vol. 24, (no. S1), pp. 962.5, April 2010. | Journal Article
 
Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers.
Przybyla, Julie A and Watts, Val J
The Journal of pharmacology and experimental therapeutics, vol. 332, (no. 3), pp. 710-9, 2010/Mar. | Journal Article
 
Ligand‐specific roles for transmembrane 5 serine residues in D1 dopamine receptor binding and activation
Chemel, Benjamin ReedBonner, Lisa A.Watts, Val J. and Nichols, David E.
The FASEB journal, vol. 24, (no. S1), pp. 584.2, April 2010. | Journal Article
 
Structures of G [alpha [superscript i1]] Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide Exchange
Johnston, ChristopherWillard, FrancisJezyk, MarkFredericks, ZoeyBodor, ErikJones, MillerBlaesius, RainerWatts, ValHarden, T.Sondek, JohnRamer, J.Siderovski, David and
Structure, vol. 13, (no. (7) ; 07, 2005), 2010-07-19. | Journal Article
 
Visualization of G protein-coupled receptor (GPCR) interactions in living cells using bimolecular fluorescence complementation (BiFC).
Vidi, Pierre-AlexandrePrzybyla, Julie AHu, Cheng Deng and Watts, Val J
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], vol. Chapter 5, pp. Unit 5.29, 2010/Apr. | Journal Article
2009
Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D(1) receptor agonist, and a reversal of enantioselectivity at D(1) versus alpha(2C) adrenergic receptors.
Przybyla, Julie ACueva, Juan PChemel, Benjamin RHsu, K JRiese, David JMcCorvy, John DChester, Julia ANichols, David E and Watts, Val J
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol. 19, (no. 2), pp. 138-46, 2009/Feb. | Journal Article
 
Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D sub(1 receptor agonist, and a reversal of enantioselectivity at D) sub(1) versus alpha sub(2C adrenergic receptors)
Przybyla, JuliePrzybyla, Julie ACueva, JuanCueva, Juan PChemel, BenjaminChemel, Benjamin RHsu, KJosephHsu, K.Riese, DavidRiese, David JMcCorvy, John DMcCorvy, JohnChester, JuliaChester, Julia ANichols, David ENichols, DavidWatts, Val and Watts, Val J
European Neuropsychopharmacology, vol. 19, (no. 2), pp. 138-146, 2009. | Journal Article
 
Fluorescent and Bioluminescent Protein-Fragment Complementation Assays in the Study of G Protein-Coupled Receptor Oligomerization and Signaling
Vidi, Pierre-Alexandre and Watts, Val
Molecular Pharmacology, vol. 75, (no. 4), pp. 739, 20090401. | Journal Article
 
The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.
Jacobo, Sarah MGuerra, Marcy LJarrard, Rachel EPrzybyla, Julie ALiu, GuohongWatts, Val J and Hockerman, Gregory H
The Journal of pharmacology and experimental therapeutics, vol. 330, (no. 1), pp. 283-93, 2009/Jul. | Journal Article
2008
Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane.
Vidi, Pierre-AlexandreChen, JijiIrudayaraj, Joseph and Watts, Val J
FEBS letters, vol. 582, (no. 29), pp. 3985-90, 2008/Dec/10. | Journal Article
 
Adenosine A sub(2) sub(A) receptors assemble into higher-order oligomers at the plasma membrane
Vidi, PAChen, J.Irudayaraj, JMK and Watts, Val J
FEBS Letters, vol. 582, (no. 29), pp. 3985-3990, 2008. | Journal Article
 
A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.
Willard, Francis SZheng, ZhenGuo, JuanDigby, Gregory JKimple, Adam JConley, Jason MJohnston, Christopher ABosch, DustinWillard, Melinda DWatts, Val JLambert, Nevin AIkeda, Stephen RDu, Quansheng and Siderovski, David P
The Journal of biological chemistry, vol. 283, (no. 52), pp. 36698-710, 2008/Dec/26. | Journal Article
 
A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS.
Willard, Francis SZheng, ZhenGuo, JuanDigby, Gregory JKimple, Adam JConley, Jason MJohnston, Christopher ABosch, DustinWillard, Melinda DWatts, Val JLambert, Nevin AIkeda, Stephen RDu, Quansheng and Siderovski, David P
Journal of biological chemistry., vol. 283, (no. 52), pp. 36698-36710, 2008. | Journal Article
 
D1 versus D2 dopamine receptor selectivity is determined by intramolecular hydrogen bonding patterns in catechol‐containing novel dopamine analogues
Chemel, Benjamin RBonner, Lisa AWatts, Val J and Nichols, David E
The FASEB journal, vol. 22, (no. S1), 2008-03-00. | Journal Article
 
Direct visualization of adenosine A 2A and dopamine D 2L receptor oligomers in a neuronal cell model
Vidi, Pierre‐AlexandreChemel, Benjamin R. and Watts, Val J.
The FASEB journal, vol. 22, (no. S1), 2008-03-00. | Journal Article
 
Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells.
Vidi, Pierre-AlexandreChemel, Benjamin RHu, Chang Deng and Watts, Val J
Molecular pharmacology, vol. 74, (no. 3), pp. 544-51, 2008/Sep. | Journal Article
2007
Adenylyl Cyclase 5: A New Clue in the Search for the "Fountain of Youth"?
Chester, Julia A and Watts, Val J
Signal Transduction Knowledge Environment, vol. 2007, (no. 413), pp. pe64-pe64, 2007. | Journal Article
 
Adenylyl Cyclase Isoforms as Novel Therapeutic Targets: An Exciting Example of Excitotoxicity Neuroprotection
Watts, Val J
Molecular Interventions, vol. 7, (no. 2), pp. 70-73, 2007. | Journal Article