183 Publications (Page 4 of 8)
2011
Mapping the catechol binding site in dopamine D₁ receptors: synthesis and evaluation of two parallel series of bicyclic dopamine analogues.Bonner, Lisa A⋅Laban, Uros⋅Chemel, Benjamin R⋅Juncosa, Jose I⋅Lill, Markus A⋅Watts, Val J and Nichols, David EChemMedChem, vol. 6, (no. 6), pp. 1024-40, 2011/Jun/6.
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Molecular and pharmacological characterization of two D(1)-like dopamine receptors in the Lyme disease vector, Ixodes scapularis.Meyer, Jason M⋅Ejendal, Karin F⋅Watts, Val J and Hill, CatherineInsect biochemistry and molecular biology, vol. 41, (no. 8), pp. 563-71, 2011/Aug.
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Molecular and pharmacological characterization of two D1-like dopamine receptors in the Lyme disease vector, Ixodes scapularisMeyer, Jason M⋅Ejendal, Karin F⋅Watts, Val J and Hill, CatherineInsect Biochemistry and Molecular Biology, vol. 41, (no. 8), pp. 563-571, 2011.
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Probing the steric space at the floor of the D1 dopamine receptor orthosteric binding domain: 7α-, 7β-, 8α-, and 8β-methyl substituted dihydrexidine analogues.Cueva, Juan P⋅Gallardo-Godoy, Alejandra⋅Juncosa, Jose I⋅Vidi, Pierre A⋅Lill, Markus A⋅Watts, Val J and Nichols, David EJournal of medicinal chemistry, vol. 54, (no. 15), pp. 5508-21, 2011/Aug/11.
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2010
AGS3 blocks D2L dopamine receptor‐mediated heterologous sensitization of adenylyl cyclase 2Conley, Jason Michael and Watts, Val JThe FASEB journal, vol. 24, (no. S1), pp. 587.5, April 2010.
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Facile synthesis of octahydrobenzo[h]isoquinolines: novel and highly potent D1 dopamine agonists.Bonner, Lisa A⋅Chemel, Benjamin R⋅Watts, Val J and Nichols, David EBioorganic & medicinal chemistry, vol. 18, (no. 18), pp. 6763-70, 2010/Sep/15.
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Facile synthesis of octahydrobenzo[h]isoquinolines: Novel and highly potent D sub(1) dopamine agonistsBonner, Lisa A⋅Chemel, Benjamin R⋅Watts, Val J and Nichols, David EBioorganic and Medicinal Chemistry, vol. 18, (no. 18), pp. 6763-6770, 2010.
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Heterologous sensitization of human AC5: dependence on heterotrimeric G proteinsEjendal, Karin F K⋅Sadana, Rachna⋅Vidi, Pierre‐Alexandre⋅Dessauer, Carmen W and Watts, Val JThe FASEB journal, vol. 24, (no. S1), pp. 962.5, April 2010.
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Ligand-induced regulation and localization of cannabinoid CB1 and dopamine D2L receptor heterodimers.Przybyla, Julie A and Watts, Val JThe Journal of pharmacology and experimental therapeutics, vol. 332, (no. 3), pp. 710-9, 2010/Mar.
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Ligand‐specific roles for transmembrane 5 serine residues in D1 dopamine receptor binding and activationChemel, Benjamin Reed⋅Bonner, Lisa A.⋅Watts, Val J. and Nichols, David E.The FASEB journal, vol. 24, (no. S1), pp. 584.2, April 2010.
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Structures of G [alpha [superscript i1]] Bound to a GDP-Selective Peptide Provides Insight into Guanine Nucleotide ExchangeJohnston, Christopher⋅Willard, Francis⋅Jezyk, Mark⋅Fredericks, Zoey⋅Bodor, Erik⋅Jones, Miller⋅Blaesius, Rainer⋅Watts, Val⋅Harden, T.⋅Sondek, John⋅Ramer, J.⋅Siderovski, David⋅ and Structure, vol. 13, (no. (7) ; 07, 2005), 2010-07-19.
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Visualization of G protein-coupled receptor (GPCR) interactions in living cells using bimolecular fluorescence complementation (BiFC).Vidi, Pierre-Alexandre⋅Przybyla, Julie A⋅Hu, Cheng Deng and Watts, Val JCurrent protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], vol. Chapter 5, pp. Unit 5.29, 2010/Apr.
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2009
Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D(1) receptor agonist, and a reversal of enantioselectivity at D(1) versus alpha(2C) adrenergic receptors.Przybyla, Julie A⋅Cueva, Juan P⋅Chemel, Benjamin R⋅Hsu, K J⋅Riese, David J⋅McCorvy, John D⋅Chester, Julia A⋅Nichols, David E and Watts, Val JEuropean neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, vol. 19, (no. 2), pp. 138-46, 2009/Feb.
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Comparison of the enantiomers of (+/-)-doxanthrine, a high efficacy full dopamine D sub(1 receptor agonist, and a reversal of enantioselectivity at D) sub(1) versus alpha sub(2C adrenergic receptors)Przybyla, Julie⋅Przybyla, Julie A⋅Cueva, Juan⋅Cueva, Juan P⋅Chemel, Benjamin⋅Chemel, Benjamin R⋅Hsu, KJoseph⋅Hsu, K.⋅Riese, David⋅Riese, David J⋅McCorvy, John D⋅McCorvy, John⋅Chester, Julia⋅Chester, Julia A⋅Nichols, David E⋅Nichols, David⋅Watts, Val and Watts, Val JEuropean Neuropsychopharmacology, vol. 19, (no. 2), pp. 138-146, 2009.
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Fluorescent and Bioluminescent Protein-Fragment Complementation Assays in the Study of G Protein-Coupled Receptor Oligomerization and SignalingVidi, Pierre-Alexandre and Watts, ValMolecular Pharmacology, vol. 75, (no. 4), pp. 739, 20090401.
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The intracellular II-III loops of Cav1.2 and Cav1.3 uncouple L-type voltage-gated Ca2+ channels from glucagon-like peptide-1 potentiation of insulin secretion in INS-1 cells via displacement from lipid rafts.Jacobo, Sarah M⋅Guerra, Marcy L⋅Jarrard, Rachel E⋅Przybyla, Julie A⋅Liu, Guohong⋅Watts, Val J and Hockerman, Gregory HThe Journal of pharmacology and experimental therapeutics, vol. 330, (no. 1), pp. 283-93, 2009/Jul.
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2008
Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane.Vidi, Pierre-Alexandre⋅Chen, Jiji⋅Irudayaraj, Joseph and Watts, Val JFEBS letters, vol. 582, (no. 29), pp. 3985-90, 2008/Dec/10.
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Adenosine A sub(2) sub(A) receptors assemble into higher-order oligomers at the plasma membraneVidi, PA⋅Chen, J.⋅Irudayaraj, JMK and Watts, Val JFEBS Letters, vol. 582, (no. 29), pp. 3985-3990, 2008.
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A point mutation to Galphai selectively blocks GoLoco motif binding: direct evidence for Galpha.GoLoco complexes in mitotic spindle dynamics.Willard, Francis S⋅Zheng, Zhen⋅Guo, Juan⋅Digby, Gregory J⋅Kimple, Adam J⋅Conley, Jason M⋅Johnston, Christopher A⋅Bosch, Dustin⋅Willard, Melinda D⋅Watts, Val J⋅Lambert, Nevin A⋅Ikeda, Stephen R⋅Du, Quansheng and Siderovski, David PThe Journal of biological chemistry, vol. 283, (no. 52), pp. 36698-710, 2008/Dec/26.
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A Point Mutation to Gαi Selectively Blocks GoLoco Motif Binding: DIRECT EVIDENCE FOR Gα·GoLoco COMPLEXES IN MITOTIC SPINDLE DYNAMICS.Willard, Francis S⋅Zheng, Zhen⋅Guo, Juan⋅Digby, Gregory J⋅Kimple, Adam J⋅Conley, Jason M⋅Johnston, Christopher A⋅Bosch, Dustin⋅Willard, Melinda D⋅Watts, Val J⋅Lambert, Nevin A⋅Ikeda, Stephen R⋅Du, Quansheng and Siderovski, David PJournal of biological chemistry., vol. 283, (no. 52), pp. 36698-36710, 2008.
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D1 versus D2 dopamine receptor selectivity is determined by intramolecular hydrogen bonding patterns in catechol‐containing novel dopamine analoguesChemel, Benjamin R⋅Bonner, Lisa A⋅Watts, Val J and Nichols, David EThe FASEB journal, vol. 22, (no. S1), 2008-03-00.
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Direct visualization of adenosine A 2A and dopamine D 2L receptor oligomers in a neuronal cell modelVidi, Pierre‐Alexandre⋅Chemel, Benjamin R. and Watts, Val J.The FASEB journal, vol. 22, (no. S1), 2008-03-00.
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Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells.Vidi, Pierre-Alexandre⋅Chemel, Benjamin R⋅Hu, Chang Deng and Watts, Val JMolecular pharmacology, vol. 74, (no. 3), pp. 544-51, 2008/Sep.
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2007
Adenylyl Cyclase 5: A New Clue in the Search for the "Fountain of Youth"?Chester, Julia A and Watts, Val JSignal Transduction Knowledge Environment, vol. 2007, (no. 413), pp. pe64-pe64, 2007.
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Adenylyl Cyclase Isoforms as Novel Therapeutic Targets: An Exciting Example of Excitotoxicity NeuroprotectionWatts, Val JMolecular Interventions, vol. 7, (no. 2), pp. 70-73, 2007.
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