183 Publications (Page 7 of 8)
1999
Impaired cholera toxin relaxation with age in rat aorta.
Chapman, J⋅Schutzer, W E⋅Watts, Val J and Mader, S L
The journals of gerontology. Series A, Biological sciences and medical sciences, vol. 54, (no. 4), pp. B154-9, 1999/Apr. | Journal Article
 
Impaired Cholera toxin relaxation with age in rat aorta
Chapman, Justin⋅Schutzer, William E⋅Watts, Val J and Mader, Scott L
The Journals of Gerontology, vol. 54A, (no. 4), pp. B154-9, Apr 1999. | Journal Article
 
Short- and long-term heterologous sensitization of adenylate cyclase by D4 dopamine receptors.
Watts, Val J⋅Vu, M N⋅Wiens, B L⋅Jovanovic, V⋅Van Tol, H H and Neve, Kim
Psychopharmacologia, vol. 141, (no. 1), pp. 83-92, 1999/Jan. | Journal Article
1998
Homologous desensitization of the D1A dopamine receptor: efficacy in causing desensitization dissociates from both receptor occupancy and functional potency.
Lewis, Mechelle M⋅Watts, Val J⋅Lawler, C P⋅Nichols, D E and Mailman, Richard M
The Journal of pharmacology and experimental therapeutics, vol. 286, (no. 1), pp. 345-53, 1998/Jul. | Journal Article
 
Selective activation of Galphao by D2L dopamine receptors in NS20Y neuroblastoma cells.
Watts, Val J⋅Wiens, B L⋅Cumbay, M G⋅Vu, M N⋅Neve, R L and Neve, K A
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 18, (no. 21), pp. 8692-9, 1998/Nov/1. | Journal Article
 
Selective Activation of Galpha o by D2L Dopamine Receptors in NS20Y Neuroblastoma Cells
Watts, Val⋅Wiens, Brenda⋅Cumbay, Medhane⋅Vu, Minh⋅Neve, Rachael and Neve, Kim
Journal of Neuroscience, vol. 18, (no. 21), pp. 8692, 19981101. | Journal Article
 
Selective Activation of Gαo by D2LDopamine Receptors in NS20Y Neuroblastoma Cells
Watts, Val J⋅Wiens, Brenda L⋅Cumbay, Medhane G⋅Vu, Minh N⋅Neve, Rachael L and Neve, Kim A
The Journal of Neuroscience, vol. 18, (no. 21), pp. 8699, 19981101. | Journal Article
1997
Activation of type II adenylate cyclase by D2 and D4 but not D3 dopamine receptors.
Watts, Val J and Neve, Kim
Molecular Pharmacology, vol. 52, (no. 2), pp. 181-6, 1997/Aug. | Journal Article
 
Activation of Type II Adenylate Cyclase by D2and D4but Not D3Dopamine Receptors
Watts, Val J and Neve, Kim A
Molecular Pharmacology, vol. 52, (no. 2), pp. 186, 1997-08-01. | Journal Article
 
Further definition of the D1 dopamine receptor pharmacophore: synthesis of trans-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphth[2,1-b]azepines as rigid analogues of beta-phenyldopamine.
Negash, K⋅Nichols, David E⋅Watts, Val J and Mailman, Richard M
Journal of medicinal chemistry, vol. 40, (no. 14), pp. 2140-7, 1997/Jul/4. | Journal Article
 
Further Definition of the D1 Dopamine Receptor Pharmacophore:  Synthesis of trans-6,6a,7,8,9,13b-Hexahydro-5H-benzo[d]naphth[2,1-b]azepines as Rigid Analogues of β-Phenyldopamine
Negash, Kitaw⋅Nichols, David E⋅Watts, Val J and Mailman, Richard B
Journal of Medicinal Chemistry, vol. 40, (no. 14), pp. 2147, 19970704. | Journal Article
1996
8,9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline:  A Potent Full Dopamine D1 Agonist Containing a Rigid β-Phenyldopamine Pharmacophore
Ghosh, Debasis⋅Snyder, Scott E⋅Watts, Val J⋅Mailman, Richard B and Nichols, David E
Journal of Medicinal Chemistry, vol. 39, (no. 2), pp. 555, 19960119. | Journal Article
 
9-Dihydroxy-2,3,7,11b-tetrahydro-1H-naph[1,2,3-de]isoquinoline: a potent full dopamine D1 agonist containing a rigid-beta-phenyldopamine pharmacophore.
Ghosh, D⋅Snyder, S E⋅Watts, Val J⋅Mailman, Richard M and Nichols, D E
Journal of medicinal chemistry, vol. 39, (no. 2), pp. 549-55, 1996/Jan/19. | Journal Article
 
Conformational analysis of D1 dopamine receptor agonists: pharmacophore assessment and receptor mapping.
Mottola, D M⋅Laiter, S⋅Watts, Val J⋅Tropsha, A⋅Wyrick, S D⋅Nichols, D E and Mailman, Richard M
Journal of medicinal chemistry, vol. 39, (no. 1), pp. 285-96, 1996/Jan/5. | Journal Article
 
Sensitization of endogenous and recombinant adenylate cyclase by activation of D2 dopamine receptors.
Watts, Val J and Neve, Kim
Molecular Pharmacology, vol. 50, (no. 4), pp. 966-76, 1996/Oct. | Journal Article
1995
Concentration of enzyme-dependent activation of PLC-beta 1 and PLC-beta 2 by G alpha 11 and beta gamma-subunits.
Paterson, A⋅Boyer, J L⋅Watts, Val J⋅Morris, A J⋅Price, E M and Harden, T K
Cellular signalling, vol. 7, (no. 7), pp. 709-20, 1995/Sep. | Journal Article
 
Concentration of enzyme-dependent activation of PLC-β1 and PLC-β2 by Gα11 and βγ-subunits
Paterson, Andrew⋅Boyer, JoséLuis⋅Watts, Val J⋅Morris, Andrew J⋅Price, Elmer M and Harden, T.Kendall
Cellular Signalling, vol. 7, (no. 7), pp. 720, 1995-09-00. | Journal Article
 
Evaluation of cis- and trans-9- and 11-hydroxy-5,6,6a,7,8,12b-hexahydrobenzo[a]phenanthridines as structurally rigid, selective D1 dopamine receptor ligands.
Brewster, W K⋅Nichols, David E⋅Watts, Val J⋅Riggs, R M⋅Mottola, D and Mailman, Richard M
Journal of medicinal chemistry, vol. 38, (no. 2), pp. 318-27, 1995/Jan/20. | Journal Article
 
"Full" dopamine D1 agonists in human caudate: biochemical properties and therapeutic implications.
Gilmore, John H⋅Watts, Val J⋅Lawler, C P⋅Noll, E P⋅Nichols, D E and Mailman, Richard M
Neuropharmacology, vol. 34, (no. 5), pp. 481-8, 1995/May. | Journal Article
 
Interhemispheric modulation of dopamine receptor interactions in unilateral 6-OHDA rodent model
Lawler, CP⋅Gilmore, John H⋅Watts, Val J⋅Walker, QD⋅Southerland, SB⋅Cook, LL⋅Mathis, CA and Mailman, Richard
Synapse, vol. 21, (no. 4), pp. 299-311, 1995. | Journal Article
 
LSD and structural analogs: pharmacological evaluation at D1 dopamine receptors.
Watts, Val J⋅Lawler, C P⋅Fox, D R⋅Neve, K A⋅Nichols, D E and Mailman, Richard M
Psychopharmacologia, vol. 118, (no. 4), pp. 401-9, 1995/Apr. | Journal Article
 
Spare receptors and intrinsic activity: studies with D1 dopamine receptor agonists.
Watts, Val J⋅Lawler, C P⋅Gonzales, A J⋅Zhou, Q Y⋅Civelli, O⋅Nichols, D E and Mailman, Richard M
Synapse, vol. 21, (no. 2), pp. 177-87, 1995/Oct. | Journal Article
 
Synthesis and biological evaluation of a series of substituted benzo[a]phenanthridines as agonists at D1 and D2 dopamine receptors.
Knoerzer, T A⋅Watts, Val J⋅Nichols, D E and Mailman, Richard M
Journal of medicinal chemistry, vol. 38, (no. 16), pp. 3062-70, 1995/Aug/4. | Journal Article
 
Synthesis and evaluation of 6,7-dihydroxy-2,3,4,8,9,13b-hexahydro-1H- benzo[6,7]cyclohepta[1,2,3-ef][3]benzazepine, 6,7-dihydroxy- 1,2,3,4,8,12b-hexahydroanthr[10,4a,4-cd]azepine, and 10-(aminomethyl)-9,10- dihydro-1,2-dihydroxyanthracene as conformationally restricted analogs of beta-phenyldopamine.
Snyder, S E⋅Aviles-Garay, F A⋅Chakraborti, R⋅Nichols, David E⋅Watts, Val J and Mailman, Richard M
Journal of medicinal chemistry, vol. 38, (no. 13), pp. 2395-409, 1995/Jun/23. | Journal Article
 
Synthesis and Evaluation of 6,7-Dihydroxy-2,3,4,8,9,13b-hexahydro-1H-benzo[6,7]cyclohepta[1,2,3-ef][3]benzazepine, 6,7-Dihydroxy-1,2,3,4,8,12b-hexahydroanthr[10,4a,4-cd]azepine, and 10-(Aminomethyl)-9,10-dihydro-1,2-dihydroxyanthracene as Conformationally Restricted Analogs of .beta.-Phenyldopamine
Snyder, Scott E⋅Aviles-Garay, Felix A⋅Chakraborti, Ratna⋅Nichols, David E⋅Watts, Val J and Mailman, Richard B
Journal of Medicinal Chemistry, vol. 38, (no. 13), pp. 2409, 19950601. | Journal Article