183 Publications (Page 3 of 8)
2014
Drug-induced sensitization of adenylyl cyclase: assay streamlining and miniaturization for small molecule and siRNA screening applications.
Conley, Jason M⋅Brust, Tarsis F⋅Xu, Ruqiang⋅Burris, Kevin D and Watts, Val J
Journal of visualized experiments : JoVE, (no. 83), pp. e51218, 2014. | Journal Article
 
G protein contribution to complex signaling pathways downstream of the dopamine D2L receptor (662.10)
Brust, Tarsis⋅Hayes, Michael⋅Roman, David and Watts, Val
The FASEB journal, vol. 28, (no. S1), pp. n/a, April 2014. | Journal Article
 
l‐Stepholidine is a potent pan‐dopamine receptor antagonist at G protein and β‐arrestin mediated signaling in vitro (662.5)
Meade, Julie⋅Free, R⋅Miller, Nicole⋅Moritz, Amy⋅Conroy, Jennie⋅Doyle, Trevor⋅Watts, Val and Sibley, David
The FASEB journal, vol. 28, (no. S1), pp. n/a, April 2014. | Journal Article
 
Peptide modulators of adenylyl cyclase signaling: modulation of receptor‐mediated Gβγ signaling (843.6)
Soto Velasquez, Monica⋅Spence, John⋅Brust, Tarsis⋅Perez, Minervo⋅Parker, Laurie and Watts, Val
The FASEB journal, vol. 28, (no. S1), pp. n/a, April 2014. | Journal Article
 
Polydopamine-Based Simple and Versatile Surface Modification of Polymeric Nano Drug Carriers
Park, Joonyoung⋅Park, Joonyoung⋅Brust, Tarsis F⋅Brust, Tarsis F⋅Lee, Hong Jae⋅Lee, Hong J⋅Lee, Sang Cheon⋅Lee, Sang Youp⋅Watts, Val J⋅Watts, Val J⋅Yeo, Yoon and Yeo, Yoon
ACS nano, vol. 8, (no. 4), pp. 3356, 2014-04-22. | Journal Article
2013
Bimolecular fluorescence complementation analysis of G protein-coupled receptor dimerization in living cells.
Ejendal, Karin F⋅Conley, Jason M⋅Hu, Chang Deng and Watts, Val J
Methods in enzymology, vol. 521, pp. 259-79, 2013. | Journal Article
 
Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor.
Conley, Jason M⋅Brand, Cameron S⋅Bogard, Amy S⋅Pratt, Evan P⋅Xu, Ruqiang⋅Hockerman, Gregory H⋅Ostrom, Rennolds S⋅Dessauer, Carmen W and Watts, Val J
The Journal of pharmacology and experimental therapeutics, vol. 347, (no. 2), pp. 276-87, 2013/Nov. | Journal Article
 
Differential effects of AGS3 expression on D(2L) dopamine receptor-mediated adenylyl cyclase signaling
Conley, Jason M and Watts, Val J
Cellular and molecular neurobiology, vol. 33, (no. 4), pp. 551, 2013-May. | Journal Article
 
Differential Effects of AGS3 Expression on D2L Dopamine Receptor-Mediated Adenylyl Cyclase Signaling
Conley, Jason and Watts, Val
Cellular and Molecular Neurobiology, vol. 33, (no. 4), pp. 558, 20130500. | Journal Article
 
Functional selectivity of ligands at the dopamine D2L dopamine receptor
Brust, Tarsis and Watts, Val
The FASEB journal, vol. 27, (no. S1), 2013-04-00. | Journal Article
 
Identification and characterization of novel small molecule modulators of adenylyl cyclase
Conley, Jason M⋅Bogard, Amy S⋅Brand, Cameron S⋅Dessauer, Carmen W⋅Ostrom, Rennolds S and Watts, Val J
The FASEB journal, vol. 27, (no. S1), 2013-04-00. | Journal Article
 
Re-invigorating the insecticide discovery pipeline for vector control: GPCRs as targets for the identification of next gen insecticides
Hill, Catherine A⋅Meyer, Jason M⋅Ejendal, Karin F.K⋅Echeverry, Diego F⋅Lang, Emma G⋅Avramova, Larisa V⋅Conley, Jason M and Watts, Val J
Pesticide Biochemistry and Physiology, vol. 106, (no. 3), pp. 148, July 2013. | Journal Article
2012
A "genome-to-lead" approach for insecticide discovery: pharmacological characterization and screening of Aedes aegypti D(1)-like dopamine receptors.
Meyer, Jason M⋅Ejendal, Karin F⋅Avramova, Larisa V⋅Garland-Kuntz, Elisabeth E⋅Giraldo-Calderón, Gloria I⋅Brust, Tarsis F⋅Watts, Val J and Hill, Catherine A
PLoS neglected tropical diseases, vol. 6, (no. 1), pp. e1478, 2012/Jan. | Journal Article
 
Analogues of doxanthrine reveal differences between the dopamine D1 receptor binding properties of chromanoisoquinolines and hexahydrobenzo[a]phenanthridines.
Cueva, Juan P⋅Chemel, Benjamin R⋅Juncosa, Jose I⋅Lill, Markus A⋅Watts, Val J and Nichols, David E
European journal of medicinal chemistry, vol. 48, pp. 97-107, 2012/Feb. | Journal Article
 
Comparison of the D₁ dopamine full agonists, dihydrexidine and doxanthrine, in the 6-OHDA rat model of Parkinson's disease.
McCorvy, John D⋅Watts, Val J and Nichols, David E
Psychopharmacology, vol. 222, (no. 1), pp. 81-7, 2012/Jul. | Journal Article
 
Comparison of the D^sub 1^ dopamine full agonists, dihydrexidine and doxanthrine, in the 6-OHDA rat model of Parkinson's disease
Mccorvy, John D⋅Watts, Val J and Nichols, David E
Psychopharmacology, vol. 222, (no. 1), pp. 81-7, Jul 2012. | Journal Article
 
Discovery of antagonists of tick dopamine receptors via chemical library screening and comparative pharmacological analyses.
Ejendal, Karin F⋅Meyer, Jason M⋅Brust, Tarsis F⋅Avramova, Larisa V⋅Hill, Catherine and Watts, Val J
Insect biochemistry and molecular biology, vol. 42, (no. 11), pp. 846-53, 2012/Nov. | Journal Article
 
Dopamine D(2) Receptor-Mediated Heterologous Sensitization of AC5 Requires Signalosome Assembly.
Ejendal, Karin F⋅Dessauer, Carmen W⋅Hébert, Terence E and Watts, Val J
Journal of signal transduction, vol. 2012, pp. 210324, 2012. | Journal Article
 
Identification of a 2-phenyl-substituted octahydrobenzo[f]quinoline as a dopamine D₃ receptor-selective full agonist ligand.
Clark, Alia H⋅McCorvy, John D⋅Conley, Jason M⋅Williams, Whitney K⋅Bekkam, Markondaiah⋅Watts, Val J and Nichols, David E
Bioorganic & medicinal chemistry, vol. 20, (no. 21), pp. 6366-74, 2012/Nov/1. | Journal Article
 
Ligand-specific roles for transmembrane 5 serine residues in the binding and efficacy of dopamine D(1) receptor catechol agonists.
Chemel, Benjamin R⋅Bonner, Lisa A⋅Watts, Val J and Nichols, David E
Molecular pharmacology, vol. 81, (no. 5), pp. 729-38, 2012/May. | Journal Article
2011
Assessment of dopamine D₁ receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393.
Clark, Alia H⋅McCorvy, John D⋅Watts, Val J and Nichols, David E
Bioorganic & medicinal chemistry, vol. 19, (no. 18), pp. 5420-31, 2011/Sep/15. | Journal Article
 
Assessment of dopamine D sub(1 receptor affinity and efficacy of three tetracyclic conformationally-restricted analogs of SKF38393)
Clark, Alia H⋅McCorvy, John D⋅Watts, Val J and Nichols, David E
Bioorganic and Medicinal Chemistry, vol. 19, (no. 18), pp. 5420-5431, 2011. | Journal Article
 
D2L dopamine receptor‐mediated heterologous sensitization of adenylyl cyclase 2 is Gβγ subunit‐dependent
Conley, Jason Michael and Watts, Val
The FASEB journal, vol. 25, pp. 1011.2, April 2011. | Journal Article
 
Differential uptake and storage of dehydroergosterol (DHE) as a marker for Niemann Pick Type C: Implications for drug screening and mechanistic studies
Wright, Rachel E⋅Wright, Rachel E⋅Watts, Val J⋅Watts, Val J⋅Barker, Eric L and Barker, Eric L
The FASEB journal, vol. 25, pp. 799.1, April 2011. | Journal Article
 
Fluorescent protein complementation assays: new tools to study G protein-coupled receptor oligomerization and GPCR-mediated signaling
Vidi, Pierre-Alexandre⋅Ejendal, Karin F⋅Przybyla, Julie A and Watts, Val J
Molecular and Cellular Endocrinology, vol. 331, (no. 2), pp. 185-193, 2011. | Journal Article