144 Publications (Page 5 of 6)
2008
KIT associated intracellular tyrosines play an essential role in EpoR co-signaling.
Hong, Li⋅Hong, Li⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Chen, Jinbiao⋅Chen, Jinbiao⋅Harris, Chad⋅Harris, Chad⋅Wojchowski, Don M⋅Wojchowski, Don M⋅Kapur, Reuben and Kapur, Reuben
Cellular signalling, vol. 20, (no. 8), pp. 1513-20, 2008/Aug. | Journal Article
 
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1
Yan, Jincheng⋅Yan, Jincheng⋅Chen, Shi⋅Chen, Shi⋅Zhang, Yingze⋅Zhang, Yingze⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Yan⋅Li, Yan⋅Wu, Xiaohua⋅Wu, Xiaohua⋅Yuan, Jin⋅Yuan, Jin⋅Robling, Alexander⋅Robling, Alexander G⋅Kapur, Reuben⋅Kapur, Reuben⋅Chan, Rebecca⋅Chan, Rebecca J⋅Yang, Feng Chun and Yang, Feng Chun
Human Molecular Genetics, vol. 17, (no. 12), pp. 1876, Jun 15, 2008. | Journal Article
 
Rac1 mediates the osteoclast gains-in-function induced by haploinsufficiency of Nf1.
Yan, Jincheng⋅Yan, Jincheng⋅Chen, Shi⋅Chen, Shi⋅Zhang, Yingze⋅Zhang, Yingze⋅Li, Xiaohong⋅Li, Xiaohong⋅Li, Yan⋅Li, Yan⋅Wu, Xiaohua⋅Wu, Xiaohua⋅Yuan, Jin⋅Yuan, Jin⋅Robling, Alexander⋅Robling, Alexander G⋅Kapur, Reuben⋅Karpur, Reuben⋅Chan, Rebecca⋅Chan, Rebecca J⋅Yang, Feng Chun and Yang, Feng Chun
Human molecular genetics, vol. 17, (no. 7), pp. 936-48, 2008/Apr/1. | Journal Article
 
Requirement for p85[alpha] regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT
Munugalavadla, Veerendra⋅Sims, Emily⋅Chan, Rebecca⋅Lenz, Stephen and Kapur, Reuben
Experimental Hematology, vol. 36, (no. 3), pp. 301, 20080301. | Journal Article
 
Requirement for p85alpha regulatory subunit of class IA PI3K in myeloproliferative disease driven by an activation loop mutant of KIT
Munugalavadla, Veerendra⋅Sims, Emily C⋅Chan, Rebecca J⋅Lenz, Stephen D and Kapur, Reuben
Experimental hematology, vol. 36, (no. 3), pp. 301, 2008-Mar. | Journal Article
 
The p85α Subunit of Class IA Phosphatidylinositol 3-Kinase Regulates the Expression of Multiple Genes Involved in Osteoclast Maturation and Migration
Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Sims, Emily C⋅Sims, Emily⋅Sims, Emily⋅Krishnan, Subha⋅Krishnan, Subha⋅Krishnan, Subha⋅Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅Yan, Jincheng⋅Yan, Jincheng⋅Yan, Jincheng⋅Li, Huijie⋅Li, Huijie⋅Li, Huijie⋅Niziolek, Paul⋅Niziolek, Paul⋅Niziolek, Paul J⋅Takemoto, Clifford⋅Takemoto, Clifford⋅Takemoto, Clifford⋅Robling, Alexander⋅Robling, Alexander⋅Robling, Alexander⋅Yang, Feng-Chun⋅Yang, Feng Chun⋅Yang, Feng-Chun⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Molecular and Cellular Biology, vol. 28, (no. 23), pp. 7198, 20081201. | Journal Article
 
The Role of Protein Tyrosine Phosphatase, Shp2, in FLT3-ITD-Induced Leukemogenesis
Nabinger, Sarah C⋅Fukuda, Seiji⋅Kapur, Reuben and Chan, Rebecca
Blood, vol. 112, (no. 11), pp. 1804, 2008-11-16. | Journal Article
2007
Focal Adhesion Kinase Regulates Critical Functions in Hematopoiesis
Vemula, Sasidhar⋅Vemula, Sasidhar⋅Abratigue, Benjamin P⋅Abratigue, Benjamin P⋅Gandra, Premchand⋅Gandra, Premchand⋅O’Malley, John T⋅O’Malley, John T⋅Ahyi, Ayek-Nati N⋅Ahyi, Ayek-Nati N⋅Stritesky, Gretta⋅Stritesky, Gretta⋅Yeh, Norman⋅Yeh, Norman⋅Kaplan, Mark⋅Kaplan, Mark⋅Beggs, Hillary⋅Beggs, Hillary⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 110, (no. 11), pp. 1407, 2007-11-16. | Journal Article
 
Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis
Munugalavadla, Veerendra⋅Sims, Emily C⋅Borneo, Jovencio⋅Chan, Rebecca J and Kapur, Reuben
Blood, vol. 110, (no. 5), pp. 1620, 2007-Sep-01. | Journal Article
 
Involvement of Fyn kinase in Kit and integrin-mediated Rac activation, cytoskeletal reorganization, and chemotaxis of mast cells
Samayawardhena, Lionel A⋅Samayawardhena, Lionel A⋅Kapur, Reuben⋅Kapur, Reuben⋅Craig, Andrew W and Craig, Andrew W B
Blood, vol. 109, (no. 9), pp. 3686, 2007-May-01. | Journal Article
 
Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
Li, Yu⋅Li, Yu⋅Li, Yu⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅De, Pradip⋅De, Pradip⋅De, Pradip⋅Chang, Hua-Chen⋅Chang, Hua Chen⋅Chang, Hua-Chen⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Christopherson, Kent⋅Christopherson, Kent W⋅Christopherson, Kent⋅Paranavitana, Nivanka⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Munugulavadla, Veerendra⋅Munugulavadla, Veerendra⋅Munugulavadla, Veerendra⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Stone, James C⋅Stone, James⋅Stone, James⋅Kaplan, Mark⋅Kaplan, Mark H⋅Kaplan, Mark⋅Dinauer, Mary C⋅Dinauer, Mary⋅Dinauer, Mary⋅Durden, Donald⋅Durden, Donald⋅Durden, Donald L⋅Quilliam, Lawrence⋅Quilliam, Lawrence A and Quilliam, Lawrence
Journal of Immunology, vol. 179, (no. 12), pp. 8322-8331, 2007. | Journal Article
 
Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins1
Li, Yu⋅Li, Yu⋅Li, Yu⋅Li, Yu⋅Li, Yu⋅Li, Yu⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅De, Pradip⋅De, Pradip⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Christopherson, Kent W⋅Christopherson, Kent W⋅Christopherson, Kent W⋅Christopherson, Kent W⋅Christopherson, Kent W⋅Christopherson, Kent W⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka C⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Stone, James C⋅Stone, James C⋅Stone, James C⋅Stone, James C⋅Stone, James C⋅Stone, James C⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Kaplan, Mark H⋅Dinauer, Mary C⋅Dinauer, Mary C⋅Dinauer, Mary C⋅Dinauer, Mary C⋅Dinauer, Mary C⋅Dinauer, Mary C⋅Durden, Donald L⋅Durden, Donald L⋅Durden, Donald L⋅Durden, Donald L⋅Durden, Donald L⋅Durden, Donald L⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A⋅Quilliam, Lawrence A and Quilliam, Lawrence A
Journal of immunology (Baltimore, Md. : 1950), vol. 179, (no. 12), pp. 8331, 2007-12-15. | Journal Article
 
Requirement for p85α Regulatory Subunit of Class IA PI3Kinase and Rac2 GTPase in Myeloproliferative Disease Driven by Activation Loop Mutant of KIT
Munugalavadla, Veerendra⋅Sims, Emily C⋅Lenz, Stephen D and Kapur, Reuben
Blood, vol. 110, (no. 11), pp. 89, 2007-11-16. | Journal Article
 
Src family kinase–mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors
Borneo, Jovencio⋅Borneo, Jovencio⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Sims, Emily C⋅Sims, Emily⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Orschell, Christie M⋅Orschell, Christie⋅Yoder, Merv⋅Yoder, Merv⋅Kapur, Reuben and Kapur, Reuben
Experimental Hematology, vol. 35, (no. 7), pp. 1037, 2007. | Journal Article
 
Stat3 and Stat4 direct development of IL-17-secreting Th cells.
Mathur, Anubhav N⋅Chang, Hua Chen⋅Zisoulis, Dimitrios G⋅Stritesky, Gretta L⋅Yu, Qing⋅O'Malley, John T⋅Kapur, Reuben⋅Levy, David E⋅Kansas, Geoffrey S and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 178, (no. 8), pp. 4901-7, 2007/Apr/15. | Journal Article
2006
Genetic reduction of class IA PI-3 kinase activity alters fetal hematopoiesis and competitive repopulating ability of hematopoietic stem cells in vivo
Haneline, Laura S⋅Haneline, Laura S⋅Haneline, Laura S⋅White, Hilary⋅White, Hilary⋅White, Hilary⋅Yang, Feng Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Chen, Shi⋅Chen, Shi⋅Chen, Shi⋅Orschell, Christie⋅Orschell, Christie M⋅Orschell, Christie⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Ingram, David A⋅Ingram, David A and Ingram, David A
Blood, vol. 107, (no. 4), pp. 1382, 2006-Feb-15. | Journal Article
 
Neurofibromin plays a critical role in modulating osteoblast differentiation of mesenchymal stem/progenitor cells
Wu, Xiaohua⋅Wu, Xiaohua⋅Estwick, Selina A⋅Estwick, Selina A⋅Chen, Shi⋅Chen, Shi⋅Yu, Menggang⋅Yu, Menggang⋅Ming, Wenyu⋅Ming, Wenyu⋅Nebesio, Todd D⋅Nebesio, Todd⋅Li, Yan⋅Li, Yan⋅Yuan, Jin⋅Yuan, Jin⋅Kapur, Reuben⋅Kapur, Reuben⋅Ingram, David A⋅Ingram, David⋅Yoder, Mervin C⋅Yoder, Mervin C⋅Yang, Feng Chun and Yang, Feng Chun
Human Molecular Genetics, vol. 15, (no. 19), pp. 2837-45, Oct 1, 2006. | Journal Article
2005
Enhanced TNF-alpha-induced apoptosis in Fanconi anemia type C-deficient cells is dependent on apoptosis signal-regulating kinase 1
Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Saadatzadeh, M R⋅Saadatzadeh, M Reza⋅Werne, Adam⋅Werne, Adam⋅McKenzie, Kristina A⋅McKenzie, Kristina A Wilson⋅Kapur, Reuben⋅Kapur, Reuben⋅Ichijo, Hidenori⋅Ichijo, Hidenori⋅Haneline, Laura S and Haneline, Laura S
Blood, vol. 106, (no. 13), pp. 4130, 2005-Dec-15. | Journal Article
 
Gleevec Resistant Activating Mutation of c-Kit (D816V) Demonstrates Ligand Independent Growth and Promiscuous Cooperation with Multiple Cytokine Receptors Via the p85α Subunit of Class IA PI-3Kinase
Munugalavadla, Veerendra⋅Sims, Emily⋅Borneo, Jovencio and Kapur, Reuben
Blood, vol. 106, (no. 11), pp. 3530, 2005-11-16. | Journal Article
 
Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor
Chan, Rebecca J⋅Chan, Rebecca⋅Leedy, Melissa B⋅Leedy, Melissa B⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Voorhorst, Cara S⋅Voorhorst, Cara S⋅Li, Yanjun⋅Li, Yanjun⋅Yu, Menggang⋅Yu, Menggang⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 105, (no. 9), pp. 3742, 2005-May-01. | Journal Article
 
p85α Regulatory Subunit of Class IA PI-3Kinase Regulates Osteoclast Function(s) and Bone Mass
Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Sims, Emily⋅Sims, Emily⋅Ingram, David A⋅Ingram, David A⋅Robling, Alexander⋅Robling, Alexander⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 106, (no. 11), pp. 2223, 2005-11-16. | Journal Article
 
Repression of c-Kit and Its Downstream Substrates by GATA-1 Inhibits Cell Proliferation during Erythroid Maturation
Munugalavadla, Veerendra⋅Dore, Louis⋅Tan, Bai⋅Hong, Li⋅Vishnu, Melanie⋅Weiss, Mitchell and Kapur, Reuben
Molecular and Cellular Biology, vol. 25, (no. 15), pp. 6759, 20050801. | Journal Article
 
Structure Function Analysis of Hematopoietic Specific Src Family Kinases Lyn, Hck and Fgr Reveal a Critical Role for Lyn’s Unique Domain in Regulating Growth of Myeloid Cells That Is Distinct from the Role of Hck and Fgr’s Unique Domain
Chen, Jinbiao⋅Chen, Jinbiao⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 106, (no. 11), pp. 68, 2005-11-16. | Journal Article
2004
c-Kit-mediated overlapping and unique functional and biochemical outcomes via diverse signaling pathways.
Hong, Li⋅Munugalavadla, Veerendra and Kapur, Reuben
Molecular and cellular biology, vol. 24, (no. 3), pp. 1401-1410, February 2004. | Journal Article
 
Genetic Evidence for a Role of Src Kinases in Mobilization, Homing and Engraftment of Hematopoietic Stem Cells: Deficiency of Src Kinases Results in Enhanced G-CSF Induced Mobilization
Borneo, Jovencio⋅Borneo, Jovencio⋅Orschell, Christie M⋅Orschell, Christie M⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 104, (no. 11), pp. 1292, 2004-11-16. | Journal Article