144 Publications (Page 3 of 6)
2014
Modulation in the Expression of p70S6 Kinase Impairs the Engraftment and Self-Renewal of Hematopoietic Stem Cells
Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ma, Peilin⋅Ma, Peilin⋅Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Liu, Yan⋅Liu, Yan⋅Plas, David R⋅Plas, David R⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 124, (no. 21), pp. 252, 2014-12-06. | Journal Article
 
Notch-Dependent Repression of miR-155 in the Bone Marrow Niche Regulates Hematopoiesis in an NF-κB-Dependent Manner
Wang, Lin⋅Wang, Lin⋅Wang, Lin⋅Zhang, Huajia⋅Zhang, Huajia⋅Zhang, Huajia⋅Rodriguez, Sonia⋅Rodriguez, Sonia⋅Rodriguez, Sonia⋅Cao, Liyun⋅Cao, Liyun⋅Cao, Liyun⋅Parish, Jonathan⋅Parish, Jonathan⋅Parish, Jonathan⋅Mumaw, Christen⋅Mumaw, Christen⋅Mumaw, Christen⋅Zollman, Amy⋅Zollman, Amy⋅Zollman, Amy⋅Kamoka, Malgorzata M⋅Kamoka, Malgorzata M⋅Kamoka, Malgorzata M⋅Mu, Jian⋅Mu, Jian⋅Mu, Jian⋅Chen, Danny Z⋅Chen, Danny Z⋅Chen, Danny Z⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅Chitteti, Brahmananda R⋅HogenEsch, Harm⋅HogenEsch, Harm⋅HogenEsch, Harm⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Tu, Xiaolin⋅Bellido, Teresita M⋅Bellido, Teresita M⋅Bellido, Teresita M⋅Boswell, H. Scott⋅Boswell, H Scott⋅Boswell, H. Scott⋅Manshouri, Taghi⋅Manshouri, Taghi⋅Manshouri, Taghi⋅Verstovsek, Srdan⋅Verstovsek, Srdan⋅Verstovsek, Srdan⋅Yoder, Mervin C⋅Yoder, Mervin C⋅Yoder, Mervin C⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Cardoso, Angelo A⋅Cardoso, Angelo A⋅Cardoso, Angelo A⋅Carlesso, Nadia⋅Carlesso, Nadia and Carlesso, Nadia
Cell Stem Cell, vol. 15, (no. 1), pp. 65, 2014-07-03. | Journal Article
 
Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice
Sharma, Namit⋅Sharma, Namit⋅Everingham, Stephanie⋅Everingham, Stephanie⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Kapur, Reuben⋅Kapur, Reuben⋅Craig, Andrew W.B and Craig, Andrew W B
Oncotarget, vol. 5, (no. 15), pp. 6141, 2014-08-15. | Journal Article
 
PRL2/PTP4A2 Phosphatase Is Important for Hematopoietic Stem Cell Self‐Renewal
Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Bai, Yunpeng⋅Bai, Yunpeng⋅Dong, Yuanshu⋅Dong, Yuanshu⋅Yu, Hao⋅Yu, Hao⋅Chen, Sisi⋅Chen, Sisi⋅Gao, Rui⋅Gao, Rui⋅Zhang, Lujuan⋅Zhang, Lujuan⋅Yoder, Mervin C⋅Yoder, Mervin C⋅Kapur, Reuben⋅Kapur, Reuben⋅Zhang, Zhong Yin⋅Zhang, Zhong‐Yin⋅Liu, Yan and Liu, Yan
STEM CELLS, vol. 32, (no. 7), pp. 1967, July 2014. | Journal Article
 
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis
Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Kobayashi, Michihiro⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Canela, Victor H⋅Canela, Victor H⋅Canela, Victor H⋅Waskow, Emily R⋅Waskow, Emily R⋅Waskow, Emily R⋅Visconte, Valeria⋅Visconte, Valeria⋅Visconte, Valeria⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Smith, Catherine C⋅Smith, Catherine C⋅Smith, Catherine C⋅Shah, Neil⋅Shah, Neil⋅Shah, Neil⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Boswell, H Scott⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Liu, Yan⋅Liu, Yan⋅Liu, Yan⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Cell Reports, vol. 9, (no. 4), pp. 1348, 2014-11-20. | Journal Article
 
Role of Rho kinases in abnormal and normal hematopoiesis.
Mali, Raghuveer Singh⋅Kapur, Simryn and Kapur, Reuben
Current opinion in hematology, vol. 21, (no. 4), pp. 271-275, July 2014. | Journal Article
 
SHP2 Phosphatase Promotes Mast Cell Chemotaxis toward Stem Cell Factor via Enhancing Activation of the Lyn/Vav/Rac Signaling Axis
Sharma, Namit⋅Sharma, Namit⋅Everingham, Stephanie⋅Everingham, Stephanie⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Kapur, Reuben⋅Kapur, Reuben⋅Craig, Andrew W and Craig, Andrew W B
Journal of immunology (Baltimore, Md. : 1950), vol. 192, (no. 10), pp. 4866, 2014-May-15. | Journal Article
 
Therapeutic Potential of Targeting the Oncogenic SHP2 Phosphatase
Zeng, Li-Fan⋅Zhang, Ruo-Yu⋅Yu, Zhi-Hong⋅Li, Sijiu⋅Wu, Li⋅Gunawan, Andrea M⋅Lane, Brandon S⋅Mali, Raghuveer S⋅Li, Xingjun⋅Chan, Rebecca J⋅Kapur, Reuben⋅Wells, Clark D and Zhang, Zhong-Yin
Journal of Medicinal Chemistry, vol. 57, (no. 15), pp. 6609, 20140814. | Journal Article
 
The small GTPase Rap1b negatively regulates neutrophil chemotaxis and transcellular diapedesis by inhibiting Akt activation
Kumar, Sachin⋅Xu, Juying⋅Kumar, Rupali Sani⋅Lakshmikanthan, Sribalaji⋅Kapur, Reuben⋅Kofron, Matthew⋅Chrzanowska-Wodnicka, Magdalena and Filippi, Marie-Dominique
The Journal of experimental medicine, vol. 211, (no. 9), pp. 1758, 2014-Aug-25. | Journal Article
2013
Heterozygous inactivation of the Nf1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway
Stansfield, Brian K⋅Bessler, Waylan K⋅Mali, Raghuveer⋅Mund, Julie A⋅Downing, Brandon⋅Li, Fang⋅Sarchet, Kara N⋅DiStasi, Matthew R⋅Conway, Simon⋅Kapur, Reuben and Ingram, David A
Human Molecular Genetics, vol. 22, (no. 5), pp. 977-988, 2013. | Journal Article
 
Pak and Rac GTPases promote oncogenic KIT-induced neoplasms.
Martin, Holly⋅Martin, Holly⋅Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Ma, Peilin⋅Ma, Peilin⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Sims, Emily⋅Sims, Emily⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Mattingly, Ray R⋅Mattingly, Ray R⋅Visconte, Valeria⋅Visconte, Valeria⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Vlaar, Cornelis P⋅Vlaar, Cornelis P⋅Dharmawardhane, Suranganie⋅Dharmawardhane, Suranganie⋅Kapur, Reuben and Kapur, Reuben
The Journal of clinical investigation, vol. 123, (no. 10), pp. 4449-63, 2013/Oct/1. | Journal Article
 
Phosphatidylinositol-3-Kinase p110d Uniquely Promotes Gain-Of-Function PTPN11-Induced GM-CSF Hypersensitivity In a Model Of Juvenile Myelomonocytic Leukemia
Goodwin, Charles B⋅Mali, Raghuveer⋅Chan, Gordon⋅Neel, Benjamin⋅Lannutti, Brian⋅Kapur, Reuben and Chan, Rebecca J
Blood, vol. 122, (no. 21), pp. 3678, 2013-11-15. | Journal Article
 
PRL2 Maintains Hematopoietic Stem and Progenitor Cells Through Regulating SCF/KIT Signaling
Kobayashi, Michihiro⋅Dong, Yuanshu⋅Yu, Hao⋅Bai, Yunpeng⋅Chen, Sisi⋅Gao, Rui⋅Yoder, Mervin C⋅Kapur, Reuben⋅Zhang, Zhong-Yin and Liu, Yan
Blood, vol. 122, (no. 21), pp. 3674, 2013-11-15. | Journal Article
 
The protein tyrosine phosphatase, Shp2, positively contributes to FLT3-ITD-induced hematopoietic progenitor hyperproliferation and malignant disease in vivo.
Nabinger, S C⋅Li, X J⋅Ramdas, B⋅He, Y⋅Zhang, X⋅Zeng, L⋅Richine, B⋅Bowling, J D⋅Fukuda, S⋅Goenka, S⋅Liu, Z⋅Feng, G-S⋅Yu, Menggang⋅Sandusky, G E⋅Boswell, H. S⋅Zhang, Z-Y⋅Kapur, Reuben and Chan, R J
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, vol. 27, (no. 2), pp. 398-408, 2013/Feb. | Journal Article
 
Unique and redundant roles of class IA PI3Kinase regulatory subunits in mast cell development
Mali, Raghuveer Singh and Kapur, Reuben
Cell Cycle, vol. 12, (no. 1), pp. 8, 1/1/2013. | Journal Article
2012
Class I(A) PI3Kinase regulatory subunit, p85α, mediates mast cell development through regulation of growth and survival related genes
Krishnan, Subha⋅Krishnan, Subha⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Koehler, Karl R⋅Koehler, Karl R⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ma, Peilin⋅Ma, Peilin⋅Hashino, Eri⋅Hashino, Eri⋅Kapur, Reuben and Kapur, Reuben
PloS one, vol. 7, (no. 1), pp. e28979, 2012-00-00. | Journal Article
 
Genetic Evidence for Critical Roles of P38α Protein in Regulating Mast Cell Differentiation and Chemotaxis through Distinct Mechanisms
Hu, Ping⋅Carlesso, Nadia⋅Xu, Mingjiang⋅Liu, Yan⋅Nebreda, Angel R⋅Takemoto, Clifford and Kapur, Reuben
The Journal of biological chemistry, vol. 287, (no. 24), pp. 20269, 2012-Jun-08. | Journal Article
 
Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL.
Wen, Qiang J⋅Goldenson, Benjamin⋅Silver, Serena J⋅Schenone, Monica⋅Dancik, Vlado⋅Huang, Zan⋅Wang, Ling-Zhi⋅Lewis, Timothy A⋅An, W F⋅Li, Xiaoyu⋅Bray, Mark-Anthony⋅Thiollier, Clarisse⋅Diebold, Lauren⋅Gilles, Laure⋅Vokes, Martha S⋅Moore, Christopher B⋅Bliss-Moreau, Meghan⋅Verplank, Lynn⋅Tolliday, Nicola J⋅Mishra, Rama⋅Vemula, Sasidhar⋅Shi, Jianjian⋅Wei, Lei⋅Kapur, Reuben⋅Lopez, Cécile K⋅Gerby, Bastien⋅Ballerini, Paola⋅Pflumio, Francoise⋅Gilliland, Dwight G⋅Goldberg, Liat⋅Birger, Yehudit⋅Izraeli, Shai⋅Gamis, Alan S⋅Smith, Franklin O⋅Woods, William G⋅Taub, Jeffrey W⋅Scherer, Christina A⋅Bradner, James E⋅Goh, Boon-Cher⋅Mercher, Thomas⋅Carpenter, Anne E⋅Gould, Robert J⋅Clemons, Paul A⋅Carr, Steven A⋅Root, David E⋅Schreiber, Stuart L⋅Stern, Andrew M and Crispino, John
Cell, vol. 150, (no. 3), pp. 575-89, 2012/Aug/3. | Journal Article
 
Inhibition of PPARγ in myeloid-lineage cells induces systemic inflammation, immunosuppression, and tumorigenesis
Wu, Lingyan⋅Wu, Lingyan⋅Wu, Lingyan⋅Wu, Lingyan⋅Wu, Lingyan⋅Yan, Cong⋅Yan, Cong⋅Yan, Cong⋅Yan, Cong⋅Yan, Cong⋅Czader, Magdalena⋅Czader, Magdalena⋅Czader, Magdalena⋅Czader, Magdalena⋅Czader, Magdalena⋅Foreman, Oded⋅Foreman, Oded⋅Foreman, Oded⋅Foreman, Oded⋅Foreman, Oded⋅Blum, Janice S⋅Blum, Janice S⋅Blum, Janice S⋅Blum, Janice S⋅Blum, Janice S⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Du, Hong⋅Du, Hong⋅Du, Hong⋅Du, Hong and Du, Hong
Blood, vol. 119, (no. 1), pp. 126, 2012-Jan-05. | Journal Article
 
p38α Protein Negatively Regulates T Helper Type 2 Responses by Orchestrating Multiple T Cell Receptor-associated Signals
Hu, Ping⋅Nebreda, Angel R⋅Liu, Yan⋅Carlesso, Nadia⋅Kaplan, Mark and Kapur, Reuben
The Journal of biological chemistry, vol. 287, (no. 40), pp. 33226, 2012-Sep-28. | Journal Article
 
p85β regulatory subunit of class IA PI3 kinase negatively regulates mast cell growth, maturation, and leukemogenesis
Krishnan, Subha⋅Krishnan, Subha⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Sims, Emily⋅Sims, Emily⋅Ma, Peilin⋅Ma, Peilin⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Hanneman, Philip⋅Hanneman, Philip⋅Beane, Joal D⋅Beane, Joal D⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 119, (no. 17), pp. 3961, 2012-Apr-26. | Journal Article
 
Regulation of the actin cytoskeleton by Rho kinase controls antigen presentation by CD1d1
Gallo, Richard M⋅Gallo, Richard M⋅Khan, Masood A⋅Khan, Masood A⋅Shi, Jianjian⋅Shi, Jianjian⋅Kapur, Reuben⋅Kapur, Reuben⋅Wei, Lei⋅Wei, Lei⋅Bailey, Jennifer C⋅Bailey, Jennifer C⋅Liu, Jianyun⋅Liu, Jianyun⋅Brutkiewicz, Randy R and Brutkiewicz, Randy R
Journal of immunology (Baltimore, Md. : 1950), vol. 189, (no. 4), pp. 1698, 2012-07-13. | Journal Article
 
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53
Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Shi, Jianjian⋅Shi, Jianjian⋅Shi, Jianjian⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Liu, Yan⋅Liu, Yan⋅Liu, Yan⋅Hanneman, Philip⋅Hanneman, Philip⋅Hanneman, Philip⋅Koehler, Karl R⋅Koehler, Karl R⋅Koehler, Karl R⋅Hashino, Eri⋅Hashino, Eri⋅Hashino, Eri⋅Wei, Lei⋅Wei, Lei⋅Wei, Lei⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 14), pp. 2878, 2012-Oct-04. | Journal Article
 
Role of intracellular tyrosines in activating KIT-induced myeloproliferative disease
Ma, Peilin⋅Ma, Peilin⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Martin, Holly⋅Martin, Holly⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Sims, Emily⋅Sims, Emily⋅Kapur, Reuben and Kapur, Reuben
Leukemia, vol. 26, (no. 7), pp. 1506, 2012-Jul. | Journal Article
 
Role of p21 Activated Kinase and Specific Guanine Exchange Factors of Rac Gtpases in Oncogenic KIT Induced Systemic Mastocytosis and Acute Myeloid Leukemia
Martin, Holly⋅Martin, Holly⋅Ma, Peilin⋅Ma, Peilin⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Sims, Emily⋅Sims, Emily⋅Vlaar, Cornelis⋅Vlaar, Cornelis⋅Dharmawardhane, Suraganie⋅Dharmawardhane, Suraganie⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 21), pp. 810, 2012-11-16. | Journal Article