144 Publications (Page 4 of 6)
2012
Role of SHP2 phosphatase in KIT-induced transformation: identification of SHP2 as a druggable target in diseases involving oncogenic KIT
Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer Singh⋅Mali, Raghuveer S⋅Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅Sims, Emily⋅Sims, Emily⋅Sims, Emily⋅Sims, Emily⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Nabinger, Sarah⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Sharma, Namit⋅Sharma, Namit⋅Sharma, Namit⋅Sharma, Namit⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Li, Shuo⋅Li, Shuo⋅Li, Shuo⋅Li, Shuo⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Craig, Andrew W⋅Craig, Andrew W⋅Craig, Andrew W⋅Craig, Andrew W⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Z. F⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 13), pp. 2678, 2012-Sep-27. | Journal Article
 
SH2 Domain-Containing Phosphatase 2 Is a Critical Regulator of Connective Tissue Mast Cell Survival and Homeostasis in Mice
Sharma, Namit⋅Sharma, Namit⋅Kumar, Vijay⋅Kumar, Vijay⋅Everingham, Stephanie⋅Everingham, Stephanie⋅Mali, Raghuveer S⋅Mali, Raghuveer⋅Kapur, Reuben⋅Kapur, Reuben⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zhang, Z. F⋅Zhang, Zhong-Yin⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Hartmann, Karin⋅Hartmann, Karin⋅Roers, Axel⋅Roers, Axel⋅Craig, Andrew and Craig, Andrew W
Molecular and Cellular Biology, vol. 32, (no. 14), pp. 2663, 20120715. | Journal Article
 
Single Nucleotide Polymorphism Array Lesions, TET2, DNMT3A, ASXL1 and CBL Mutations Are Present in Systemic Mastocytosis
Traina, Fabiola⋅Traina, Fabiola⋅Visconte, Valeria⋅Visconte, Valeria⋅Jankowska, Anna M⋅Jankowska, Anna M⋅Makishima, Hideki⋅Makishima, Hideki⋅O'Keefe, Christine L⋅O'Keefe, Christine L⋅Elson, Paul⋅Elson, Paul⋅Han, Yingchun⋅Han, Yingchun⋅Hsieh, Fred H⋅Hsieh, Fred H⋅Sekeres, Mikkael A⋅Sekeres, Mikkael A⋅Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Kalaycio, Matt⋅Kalaycio, Matt⋅Lichtin, Alan E⋅Lichtin, Alan E⋅Advani, Anjali S⋅Advani, Anjali S⋅Duong, Hien K⋅Duong, Hien K⋅Copelan, Edward⋅Copelan, Edward⋅Kapur, Reuben⋅Kapur, Reuben⋅Olalla Saad, Sara T⋅Olalla Saad, Sara T⋅Maciejewski, Jaroslaw⋅Maciejewski, Jaroslaw P⋅Tiu, Ramon V and Tiu, Ramon V
PloS one, vol. 7, (no. 8), pp. e43090, 2012-00-00. | Journal Article
 
Targeting Rho associated kinases in leukemia and myeloproliferative neoplasms
Mali, Raghuveer Singh and Kapur, Reuben
Oncotarget, vol. 3, (no. 9), pp. 910, 2012-Sep. | Journal Article
 
The Internal-Tandem-Duplication of Flt3 Mutations Augment Chemotaxis in Hematopoietic Cells by Blocking the Down-Regulation of Rho-Associated Kinase That Is Induced by SDF1/CXCR4 Signaling
Onishi, Chie⋅Mori, Satomi⋅Hirade, Tomohiro⋅Abe, Mariko⋅Yamaguchi, Seiji⋅Kapur, Reuben and Fukuda, Seiji
Blood, vol. 120, (no. 21), pp. 1319, 2012-11-16. | Journal Article
 
The Protein Tyrosine Phosphatase, Shp2, Positively Contributes to FLT3-ITD-Induced Malignant Disease in Vivo and Co-Localizes with Nuclear Phospho-STAT5 in FLT3-ITD-Expressing Leukemic Cells
Nabinger, Sarah C⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Li, Xing Jun⋅Li, Xing Jun⋅Li, Xing Jun⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅Zhang, Xian⋅Zhang, Xian⋅Zhang, Xian⋅Richine, Briana⋅Richine, Briana⋅Richine, Briana⋅Bowling, Joshua⋅Bowling, Joshua⋅Bowling, Joshua⋅Fukuda, Seiji⋅Fukuda, Seiji⋅Fukuda, Seiji⋅Goenka, Shreevrat⋅Goenka, Shreevrat⋅Goenka, Shreevrat⋅Liu, Ziyue⋅Liu, Ziyue⋅Liu, Ziyue⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Chan, Rebecca J⋅Chan, Rebecca J and Chan, Rebecca J
Blood, vol. 120, (no. 21), pp. 2420, 2012-11-16. | Journal Article
 
The Role of SHIP in the Development and Activation of Mouse Mucosal and Connective Tissue Mast Cells
Ruschmann, Jens⋅Ruschmann, Jens⋅Antignano, Frann⋅Antignano, Frann⋅Lam, Vivian⋅Lam, Vivian⋅Snyder, Kim⋅Snyder, Kim⋅Kim, Connie⋅Kim, Connie⋅Essak, Martha⋅Essak, Martha⋅Zhang, Angela⋅Zhang, Angela⋅Lin, Ann H⋅Lin, Ann Hsu-An⋅Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Kapur, Reuben⋅Kapur, Reuben⋅Krystal, Gerald and Krystal, Gerald
Journal of immunology (Baltimore, Md. : 1950), vol. 188, (no. 8), pp. 3850, 2012-Apr-15. | Journal Article
 
Unraveling a Novel Mechanism of Stat5 Regulation by FAK and Rac1 in Flt3ITD Induced Leukemogenesis
Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Boswell, H. Scott⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 120, (no. 21), pp. 858, 2012-11-16. | Journal Article
2011
Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
Ma, Peilin⋅Ma, Peilin⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Chen, Jinbiao⋅Chen, Jinbiao⋅Sims, Emily⋅Sims, Emily⋅Borneo, Jovencio⋅Borneo, Jovencio⋅Kondo, Takako⋅Kondo, Takako⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Mali, Raghuveer⋅Mali, Raghuveer S⋅Li, Shuo⋅Li, Shuo⋅Hashino, Eri⋅Hashino, Eri⋅Takemoto, Clifford⋅Takemoto, Clifford⋅Kapur, Reuben and Kapur, Reuben
Molecular and cellular biology, vol. 31, (no. 19), pp. 4052-62, 2011/Oct. | Journal Article
 
KIT Induced Myeloproliferative Disease Is Dependent on PI3Kinase and SHP2 Phosphatase: Identification of SHP2 As a Druggable Target for Treating MPD and AML
Ma, Peilin⋅Ma, Peilin⋅Ma, Peilin⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Martin, Holly⋅Martin, Holly⋅Martin, Holly⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅He, Yantao⋅He, Yantao⋅He, Yantao⋅Sims, Emily⋅Sims, Emily⋅Sims, Emily⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Li, Shuo⋅Li, Shuo⋅Li, Shuo⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Chatterjee, Anindya⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Craig, Andrew⋅Craig, Andrew⋅Craig, Andrew⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Bunting, Kevin D⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Chan, Rebecca J⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 118, (no. 21), pp. 868, 2011-11-18. | Journal Article
 
KIT signaling regulates MITF expression through miRNAs in normal and malignant mast cell proliferation
Lee, Youl-Nam⋅Lee, Youl-Nam⋅Brandal, Stephanie⋅Brandal, Stephanie⋅Noel, Pierre⋅Noel, Pierre⋅Wentzel, Erik⋅Wentzel, Erik⋅Mendell, Joshua T⋅Mendell, Joshua T⋅McDevitt, Michael A⋅Mc Devitt, Michael A⋅Kapur, Reuben⋅Kapur, Reuben⋅Carter, Melody C⋅Carter, Melody⋅Metcalfe, Dean D⋅Metcalfe, Dean D⋅Takemoto, C. and Takemoto, Clifford M
Blood, vol. 117, (no. 13), pp. 3640, 2011-Mar-31. | Journal Article
 
Myeloid-Specific Expression of Human Lysosomal Acid Lipase Corrects Malformation and Malfunction of Myeloid-Derived Suppressor Cells in lal-/- Mice
Qu, Peng⋅Qu, Peng⋅Qu, Peng⋅Qu, Peng⋅Yan, Cong⋅Yan, Cong⋅Yan, Cong⋅Yan, Cong⋅Blum, Janice S⋅Blum, Janice S⋅Blum, Janice S⋅Blum, Janice S⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Du, Hong⋅Du, Hong⋅Du, Hong and Du, Hong
Journal of immunology (Baltimore, Md. : 1950), vol. 187, (no. 7), pp. 3866, 2011-Oct-01. | Journal Article
 
p85alpha regulates osteoblast differentiation by cross-talking with the MAPK pathway.
Wu, Xiaohua⋅Wu, Xiaohua⋅Chen, Shi⋅Chen, Shi⋅Orlando, Selina A⋅Orlando, Selina A⋅Yuan, Jin⋅Yuan, Jin⋅Kim, Edward T⋅Kim, Edward T⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Mali, Raghuveer S⋅Mali, Raghuveer S⋅Kapur, Reuben⋅Kapur, Reuben⋅Yang, Feng-Chun and Yang, Feng Chun
The Journal of biological chemistry, vol. 286, (no. 15), pp. 13512-21, 2011/Apr/15. | Journal Article
 
Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL.
Mali, Raghuveer S⋅Mali, Raghuveer Singh⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ma, Peilin⋅Ma, Peilin⋅Shi, Jianjian⋅Shi, Jianjian⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Sims, Emily⋅Sims, Emily⋅Wei, Lei⋅Wei, Lei⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Nabinger, Sarah C⋅Nabinger, Sarah C⋅Goodwin, Charles B⋅Goodwin, Charles B⋅Chan, Rebecca J⋅Chan, Rebecca⋅Traina, Fabiola⋅Traina, Fabiola⋅Visconte, Valeria⋅Visconte, Valeria⋅Tiu, Ramon V⋅Tiu, Ramon V⋅Lewis, Timothy A⋅Lewis, Timothy A⋅Stern, Andrew M⋅Stern, Andrew M⋅Wen, Qiang J⋅Wen, Qiang⋅Crispino, John⋅Crispino, John D⋅Boswell, H. Scott⋅Boswell, H. S⋅Kapur, Reuben and Kapur, Reuben
Cancer cell, vol. 20, (no. 3), pp. 357-69, 2011/Sep/13. | Journal Article
 
ROCK1 Functions As a Critical Regulator of Stress Erythropoiesis and Survival by Regulating p53
Vemula, Sasidhar⋅Vemula, Sasidhar⋅Shi, Jianjian⋅Shi, Jianjian⋅Mali, Raghuveer⋅Mali, Raghuveer⋅Ma, Peilin⋅Ma, Peilin⋅Hanneman, Philip⋅Hanneman, Philip⋅Wei, Lei⋅Wei, Lei⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 118, (no. 21), pp. 916, 2011-11-18. | Journal Article
2010
Essential role for focal adhesion kinase in regulating stress hematopoiesis.
Vemula, Sasidhar⋅Vemula, Sasidhar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Hanneman, Philip⋅Hanneman, Philip⋅Martin, Joseph⋅Martin, Joseph⋅Beggs, Hilary⋅Beggs, Hilary E⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 116, (no. 20), pp. 4103-15, 2010/Nov/18. | Journal Article
 
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
Lasater, EA⋅Li, F.⋅Bessler, WK⋅Estes, ML⋅Vemula, S.⋅Hingtgen, Cynthia M⋅Dinauer, Mary C⋅Kapur, Reuben⋅Conway, Simon and Ingram, David A
Journal of Clinical Investigation, vol. 120, (no. 3), pp. 859-870, 2010. | Journal Article
2009
Differential Role of Class 1A PI 3-Kinase Regulatory Subunits in Mast Cell Growth, Maturation and Survival
Mali, Raghuveer⋅Krishnan, Subha⋅Baskar, Ramdas⋅Munugalavadla, Veerendra⋅Sims, Emily⋅Hanneman, Philip and Kapur, Reuben
Blood, vol. 114, (no. 22), pp. 77, 2009-11-20. | Journal Article
 
Distinct roles of stress-activated protein kinases in Fanconi anemia type C-deficient hematopoiesis
Saadatzadeh, M R⋅Saadatzadeh, M Reza⋅Bijangi-Vishehsaraei, Khadijeh⋅Bijangi-Vishehsaraei, Khadijeh⋅Kapur, Reuben⋅Kapur, Reuben⋅Haneline, Laura S and Haneline, Laura S
Blood, vol. 113, (no. 12), pp. 2660, 2009-Mar-19. | Journal Article
 
Genetic Disruption of the PI3K Regulatory Subunit, p85α Partially Normalizes Gain-of-Function PTPN11-Induced Hypersensitivity to GM-CSF in Hematopoietic Progenitors
Goodwin, Charles B⋅Goodwin, Charles B⋅Yang, Zhenyun⋅Yang, Zhenyun⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Yin, Fuqin⋅Yin, Fuqin⋅Kapur, Reuben⋅Kapur, Reuben⋅Chan, Rebecca J and Chan, Rebecca J
Blood, vol. 114, (no. 22), pp. 3968, 2009-11-20. | Journal Article
 
Rho Kinase Inhibitors as Potential Therapeutic Agents for Oncogenic KIT, FLT3, and BCR-ABL Induced Leukemogenesis
Mali, Raghuveer⋅Mali, Raghuveer⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Sims, Emily⋅Sims, Emily⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 114, (no. 22), pp. 3909, 2009-11-20. | Journal Article
 
Role of Focal Adhesion Kinase in Myelotoxicity, Inflammatory Stress Response and Myeloid Cell Functions
Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Hanneman, Philip⋅Hanneman, Philip⋅Hanneman, Philip⋅Beggs, Hillary⋅Beggs, Hillary⋅Beggs, Hillary⋅Kapur, Reuben⋅Kapur, Reuben and Kapur, Reuben
Blood, vol. 114, (no. 22), pp. 3615, 2009-11-20. | Journal Article
 
Role of Intracellular Tyrosine Residues in Oncogenic KIT- Induced Transformamtion
Ma, Peilin⋅Martin, Holly⋅Sims, Emily⋅Baskar, Ramdas⋅Ghosh, Joy and Kapur, Reuben
Blood, vol. 114, (no. 22), pp. 1435, 2009-11-20. | Journal Article
 
Targeting the Protein Phosphatase, Shp2, Reduces FLT3-ITD-Induced Hyperproliferation of Murine Hematopoietic Progenitors
Nabinger, Sarah C⋅He, Yantao⋅Yin, Fuqin⋅Zhang, Xian⋅Senbanjo, Linda⋅Fukuda, Seiji⋅Yu, Menggang⋅Feng, Gen-Sheng⋅Zhang, Zhong-Yin⋅Kapur, Reuben and Chan, Rebecca J
Blood, vol. 114, (no. 22), pp. 827, 2009-11-20. | Journal Article
2008
Deficiency of Src family kinases compromises the repopulating ability of hematopoietic stem cells.
Orschell, Christie M⋅Orschell, Christie⋅Borneo, Jovencio⋅Borneo, Jovencio⋅Munugalavadla, Veerendra⋅Munugalavadla, Veerendra⋅Ma, Peilin⋅Ma, Peilin⋅Sims, Emily⋅Sims, Emily⋅Ramdas, Baskar⋅Ramdas, Baskar⋅Yoder, Mervin⋅Yoder, Mervin C⋅Kapur, Reuben and Kapur, Reuben
Experimental hematology, vol. 36, (no. 5), pp. 655-66, 2008/May. | Journal Article