The overall focus of my laboratory over more than 20 years has been on understanding the transcriptional regulation of T helper cells as they regulate inflammatory immunity.

My laboratory’s multi-level approach, performing hard-core studies on transcription factor-dependent gene regulation, defining transcription factor-mediated changes in cell function in vitro and in vivo, and ultimately showing conservation in human samples and where possible, linkage to human disease, continues to be a strength in our studies.

Our laboratory focuses broadly on understanding the transcriptional regulation of T helper cell differentiation and the regulation of inflammation by effector T helper subsets.


  • STAT proteins in regulation of inflammation
  • IL-9 immunobiology
  • Allergic disease


Past Affiliations
Oncology, Infectious Diseases and Immunology, Infectious Diseases and Immunology, Pediatrics, Immunology, Immunology, Microbiology, Microbiology
PhD, Wayne State University, Immunology and Microbiology, 1992
BSc, University of Windsor, Biology, 1987