22 Publications
2014
Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo.
Li, Fang⋅Li, Fang⋅Downing, Brandon D⋅Downing, Brandon D⋅Smiley, Lucy C⋅Smiley, Lucy C⋅Mund, Julie A⋅Mund, Julie A⋅Distasi, Matthew R⋅Distasi, Matthew R⋅Bessler, Waylan K⋅Bessler, Waylan K⋅Sarchet, Kara N⋅Sarchet, Kara N⋅Hinds, Daniel M⋅Hinds, Daniel M⋅Kamendulis, Lisa M⋅Kamendulis, Lisa M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Case, Jamie⋅Case, Jamie⋅Clapp, D. W⋅Clapp, D Wade⋅Conway, Simon J⋅Conway, Simon J⋅Stansfield, Brian K⋅Stansfield, Brian K⋅Ingram, Jr, David A and Ingram, David A
Circulation, vol. 129, (no. 11), pp. 1213-24, 2014/Mar/18. | Journal Article
2012
Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.
Hodgdon, K E⋅Hingtgen, Cynthia M and Nicol, Grant D
Neuroscience, vol. 206, pp. 237-44, 2012/Mar/29. | Journal Article
 
Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: a phase 2 trial.
Robertson, Kent A⋅Robertson, Kent A⋅Robertson, Kent A⋅Robertson, Kent⋅Robertson, Kent A⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Nalepa, Grzegorz⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Yang, Feng-Chun⋅Bowers, Daniel C⋅Bowers, Daniel C⋅Bowers, Daniel C⋅Bowers, Daniel C⋅Bowers, Daniel C⋅Ho, Chang Y⋅Ho, Chang Y⋅Ho, Chang Y⋅Ho, Chang Y⋅Ho, Chang Y⋅Hutchins, Gary D⋅Hutchins, Gary D⋅Hutchins, Gary D⋅Hutchins, Gary D⋅Hutchins, Gary D⋅Croop, James M⋅Croop, James M⋅Croop, James M⋅Croop, James M⋅Croop, James M⋅Vik, Terry A⋅Vik, Terry A⋅Vik, Terry A⋅Vik, Terry A⋅Vik, Terry A⋅Denne, Scott C⋅Denne, Scott C⋅Denne, Scott C⋅Denne, Scott C⋅Denne, Scott C⋅Parada, Luis F⋅Parada, Luis F⋅Parada, Luis F⋅Parada, Luis F⋅Parada, Luis F⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Walsh, Laurence E⋅Walsh, Laurence E⋅Walsh, Laurence E⋅Walsh, Laurence E⋅Walsh, Laurence E⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Pradhan, Kamnesh R⋅Pradhan, Kamnesh R⋅Pradhan, Kamnesh R⋅Pradhan, Kamnesh R⋅Pradhan, Kamnesh R⋅Edwards-Brown, Mary K⋅Edwards-Brown, Mary K⋅Edwards-Brown, Mary K⋅Edwards-Brown, Mary K⋅Edwards-Brown, Mary K⋅Cohen, Mervyn D⋅Cohen, Mervyn D⋅Cohen, Mervyn D⋅Cohen, Mervyn D⋅Cohen, Mervyn D⋅Fletcher, James W⋅Fletcher, James W⋅Fletcher, James W⋅Fletcher, James W⋅Fletcher, James W⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Travers, Jeffrey B⋅Staser, Karl W⋅Staser, Karl W⋅Staser, Karl W⋅Staser, Karl W⋅Staser, Karl W⋅Lee, Melissa W⋅Lee, Melissa W⋅Lee, Melissa W⋅Lee, Melissa W⋅Lee, Melissa W⋅Sherman, Marcie R⋅Sherman, Marcie R⋅Sherman, Marcie R⋅Sherman, Marcie R⋅Sherman, Marcie R⋅Davis, Cynthia J⋅Davis, Cynthia J⋅Davis, Cynthia J⋅Davis, Cynthia J⋅Davis, Cynthia J⋅Miller, Lucy C⋅Miller, Lucy C⋅Miller, Lucy C⋅Miller, Lucy C⋅Miller, Lucy C⋅Ingram, David A⋅Ingram, David A⋅Ingram, David A⋅Ingram, David A⋅Ingram, David A⋅Clapp, D W⋅Clapp, D. Wade⋅Clapp, D. Wade⋅Clapp, D. Wade and Clapp, D. Wade
The lancet oncology, vol. 13, (no. 12), pp. 1218-24, 2012/Dec. | Journal Article
 
Inhibition of transmitter release and attenuation of anti-retroviral-associated and tibial nerve injury-related painful peripheral neuropathy by novel synthetic Ca2+ channel peptides.
Wilson, Sarah M⋅Wilson, Sarah M⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Brittain, Joel M⋅Brittain, Joel M⋅Dustrude, Erik T⋅Dustrude, Erik T⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Pellman, Jessica J⋅Pellman, Jessica J⋅Yeum, Tae-Sung⋅Yeum, Tae-Sung⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅White, Fletcher A⋅White, Fletcher A⋅Khanna, Rajesh and Khanna, Rajesh
The Journal of biological chemistry, vol. 287, (no. 42), pp. 35065-77, 2012/Oct/12. | Journal Article
2011
Ras signaling pathways mediate NGF-induced enhancement of excitability of small-diameter capsaicin-sensitive sensory neurons from wildtype but not Nf1+/- mice.
Duan, J-H⋅Duan, J-H⋅Wang, Yue⋅Wang, Yue⋅Duarte, D⋅Duarte, D⋅Vasko, Michael R⋅Vasko, M R⋅Nicol, Grant D⋅Nicol, G D⋅Hingtgen, C M and Hingtgen, Cynthia M
Neuroscience letters, vol. 496, (no. 2), pp. 70-4, 2011/Jun/1. | Journal Article
 
Reduced expression of SynGAP, a neuronal GTPase-activating protein, enhances capsaicin-induced peripheral sensitization.
Duarte, Djane B⋅Duan, Jian-Hong⋅Nicol, Grant D⋅Vasko, Michael R and Hingtgen, Cynthia M
Journal of neurophysiology, vol. 106, (no. 1), pp. 309-18, 2011/Jul. | Journal Article
 
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex
Brittain, Joel M⋅Brittain, Joel M⋅Brittain, Joel M⋅Brittain, Joel M⋅Duarte, Djane B⋅Duarte, Djane B⋅Duarte, Djane B⋅Duarte, Djane B⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, Carrie⋅Johnson, Philip L⋅Johnson, Philip L⋅Johnson, Philip L⋅Johnson, Philip L⋅Liu, Naikui⋅Liu, Naikui⋅Liu, Naikui⋅Liu, Naikui⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Wang, Yuying⋅Wang, Yuying⋅Wang, Yuying⋅Wang, Yuying⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Khanna, May⋅Khanna, May⋅Khanna, May⋅Khanna, May⋅Park, Chul-kyu⋅Park, Chul-kyu⋅Park, Chul-kyu⋅Park, Chul-kyu⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Cheon, Bo M⋅Cheon, Bo M⋅Cheon, Bo M⋅Cheon, Bo M⋅Due, Michael R⋅Due, Michael R⋅Due, Michael R⋅Due, Michael R⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Meroueh, Samy⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Ji, Ru-rong⋅Ji, Ru-rong⋅Ji, Ru-rong⋅Ji, Ru-rong⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Xu, Xiao-ming⋅Xu, Xiao-ming⋅Xu, Xiao-ming⋅Xu, Xiao-ming⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Vasko, Michael R⋅Vasko, Michael R⋅Vasko, Michael R⋅Vasko, Michael R⋅White, Fletcher A⋅White, Fletcher A⋅White, Fletcher A⋅White, Fletcher A⋅Khanna, Rajesh⋅Khanna, Rajesh⋅Khanna, Rajesh and Khanna, Rajesh
Nature Medicine, vol. 17, (no. 7), pp. 822-9, Jul 2011. | Journal Article
 
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca²⁺ channel complex.
Brittain, Joel M⋅Brittain, Joel M⋅Brittain, Joel M⋅Brittain, J.M.⋅Brittain, Joel M⋅Brittain, Joel M⋅Duarte, D.B.⋅Duarte, Djane B⋅Duarte, Djane B⋅Duarte, Djane B⋅Duarte, Djane B⋅Duarte, Djane B⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Wilson, Sarah M⋅Wilson, S.M.⋅Wilson, Sarah M⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, Weiguo⋅Zhu, W.⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, Carrie⋅Ballard, C.⋅Johnson, Philip L⋅Johnson, P.L.⋅Johnson, Philip L⋅Johnson, Philip L⋅Johnson, Philip L⋅Johnson, Philip L⋅Liu, Naikui⋅Liu, Naikui⋅Liu, Naikui⋅Liu, Naikui⋅Liu, N.⋅Liu, Naikui⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Xiong, W.⋅Xiong, Wenhui⋅Xiong, Wenhui⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Ripsch, M.S.⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Wang, Yuying⋅Wang, Yuying⋅Wang, Yuying⋅Wang, Y.⋅Wang, Yuying⋅Wang, Yuying⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fehrenbacher, J.C.⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Fitz, S.D.⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Fitz, Stephanie D⋅Khanna, May⋅Khanna, May⋅Khanna, May⋅Khanna, May⋅Khanna, May⋅Khanna, M.⋅Park, C.-K.⋅Park, Chul-Kyu⋅Park, Chul-Kyu⋅Park, Chul-Kyu⋅Park, Chul-Kyu⋅Park, Chul-Kyu⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, Brian S⋅Schmutzler, B.S.⋅Cheon, Bo M⋅Cheon, B.M.⋅Cheon, Bo Myung⋅Cheon, Bo Myung⋅Cheon, Bo Myung⋅Cheon, Bo Myung⋅Due, Michael R⋅Due, Michael R⋅Due, Michael R⋅Due, Michael R⋅Due, M.R.⋅Due, Michael R⋅Brustovetsky, T.⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Brustovetsky, Tatiana⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Ashpole, N.M.⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Hudmon, A.⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Meroueh, S.O.⋅Meroueh, Samy⋅Meroueh, Samy O⋅Meroueh, Samy O⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Hingtgen, C.M.⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, Nickolay⋅Brustovetsky, N.⋅Brustovetsky, Nickolay⋅Ji, Ru-Rong⋅Ji, Ru-Rong⋅Ji, Ru-Rong⋅Ji, Ru-Rong⋅Ji, R.-R.⋅Ji, Ru Rong⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hurley, Joyce H⋅Hurley, J.H.⋅Hurley, Joyce H⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Jin, X.⋅Jin, Xiaoming⋅Jin, Xiaoming⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Shekhar, A.⋅Shekhar, Anantha⋅Shekhar, Anantha⋅Xu, Xiao-Ming⋅Xu, Xiao-Ming⋅Xu, Xiao-Ming⋅Xu, Xiao-Ming⋅Xu, Xiao-Ming⋅Xu, X. M.⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, Gerry S⋅Oxford, G.S.⋅Vasko, Michael R⋅Vasko, Michael R⋅Vasko, Michael R⋅Vasko, M.R.⋅Vasko, Michael R⋅Vasko, Michael R⋅White, Fletcher A⋅White, F.A.⋅White, Fletcher A⋅White, Fletcher A⋅White, Fletcher A⋅White, Fletcher A⋅Khanna, Rajesh⋅Khanna, Rajesh⋅Khanna, Rajesh⋅Khanna, Rajesh⋅Khanna, R. and Khanna, Rajesh
Nature medicine, vol. 17, (no. 7), pp. 822-9, 2011/Jul. | Journal Article
 
Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca super(2+) channel complex
Brittain, Joel M⋅Duarte, Djane B⋅Wilson, Sarah M⋅Zhu, Weiguo⋅Ballard, Carrie⋅Johnson, Philip L⋅Liu, Naikui⋅Xiong, Wenhui⋅Ripsch, Matthew S⋅Wang, Yuying⋅Fehrenbacher, Jill C⋅Fitz, Stephanie D⋅Khanna, May⋅Park, Chul-Kyu⋅Schmutzler, Brian S⋅Cheon, Bo M⋅Due, Michael R⋅Brustovetsky, Tatiana⋅Ashpole, Nicole M⋅Hudmon, Andy⋅Meroueh, Samy⋅Hingtgen, Cynthia M⋅Brustovetsky, Nickolay⋅Ji, Ru-Rong⋅Hurley, Joyce H⋅Jin, Xiaoming⋅Shekhar, Anantha⋅Xu, Xiao-Ming⋅Oxford, Gerry S⋅Vasko, Michael R⋅White, Fletcher A and Khanna, Rajesh
Nature Medicine, vol. 17, (no. 7), pp. 822-829, 2011. | Journal Article
2010
Augmented sodium currents contribute to the enhanced excitability of small diameter capsaicin-sensitive sensory neurons isolated from Nf1+/⁻ mice.
Wang, Yue⋅Duan, J-H⋅Hingtgen, Cynthia M and Nicol, Grant D
Journal of neurophysiology, vol. 103, (no. 4), pp. 2085-94, 2010/Apr. | Journal Article
 
Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans
Lasater, EA⋅Li, F.⋅Bessler, WK⋅Estes, ML⋅Vemula, S.⋅Hingtgen, Cynthia M⋅Dinauer, Mary C⋅Kapur, Reuben⋅Conway, Simon and Ingram, David A
Journal of Clinical Investigation, vol. 120, (no. 3), pp. 859-870, 2010. | Journal Article
 
Signaling pathways that mediate nerve growth factor-induced increase in expression and release of calcitonin gene-related peptide from sensory neurons.
Park, K A⋅Fehrenbacher, Jill C⋅Thompson, E L⋅Duarte, D B⋅Hingtgen, Cynthia M and Vasko, Michael R
Neuroscience, vol. 171, (no. 3), pp. 910-23, 2010/Dec/15. | Journal Article
2009
Regulation of N-type voltage-gated calcium channels (Cav2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons.
Chi, Xian X⋅Schmutzler, Brian S⋅Brittain, Joel M⋅Wang, Yuying⋅Hingtgen, Cynthia M⋅Nicol, Grant D and Khanna, Rajesh
Journal of cell science, vol. 122, (no. Pt 23), pp. 4351-62, 2009/Dec/1. | Journal Article
2008
Neurofibromatosis: the role of guanosine triphosphatase activating proteins in sensory neuron function.
Hingtgen, Cynthia M
Sheng li xue bao : [Acta physiologica Sinica], vol. 60, (no. 5), pp. 581-3, 2008/Oct/25. | Journal Article
2007
Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration - implications for increased neurofibroma formation during pregnancy
Nebesio, Todd D⋅Ming, Wenyu⋅Chen, Shi⋅Clegg, Travis⋅Yuan, Jin⋅Yang, Yanzhu⋅Estwick, Selina A⋅Li, Yan⋅Li, Xiaohong⋅Hingtgen, Cynthia M and Yang, Feng Chun
Glia, vol. 55, (no. 5), pp. 527-536, 2007. | Journal Article
 
Neurofibromin-deficient Schwann cells have increased lysophosphatidic acid dependent survival and migration-implications for increased neurofibroma formation during pregnancy.
Nebesio, Todd D⋅Ming, Wenyu⋅Chen, Shi⋅Clegg, Travis⋅Yuan, Jin⋅Yang, Yanzhu⋅Estwick, Selina A⋅Li, Yan⋅Li, Xiaohong⋅Hingtgen, Cynthia M and Yang, Feng Chun
Glia, vol. 55, (no. 5), pp. 527-536, April 1, 2007. | Journal Article
2006
Stimulus-evoked release of neuropeptides is enhanced in sensory neurons from mice with a heterozygous mutation of the Nf1 gene
Hingtgen, Cynthia M⋅Roy, SL and Clapp, David W
Neuroscience, vol. 137, (no. 2), pp. 637-645, 2006. | Journal Article
2005
Sensory neurons from Nf1 haploinsufficient mice exhibit increased excitability.
Wang, Yue⋅Wang, Yue⋅Nicol, Grant D⋅Nicol, G.⋅Clapp, D.⋅Clapp, D. W⋅Hingtgen, Cynthia M and Hingtgen, Cynthia
Journal of neurophysiology, vol. 94, (no. 6), pp. 3670-6, 2005/Dec. | Journal Article
2004
Isolation and culture of sensory neurons from the dorsal-root ganglia of embryonic or adult rats.
Burkey, Thomas H⋅Hingtgen, Cynthia M and Vasko, Michael R
Methods in molecular medicine, vol. 99, pp. 189-202, 2004. | Journal Article
2003
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells.
Yang, Feng Chun⋅Yang, Feng Chun⋅Ingram, David A⋅Ingram, David A⋅Chen, Shi⋅Chen, Shi⋅Hingtgen, Cynthia M⋅Hingtgen, Cynthia M⋅Ratner, Nancy⋅Ratner, Nancy⋅Monk, Kelly R⋅Monk, Kelly R⋅Clegg, Travis⋅Clegg, Travis⋅White, Hilary⋅White, Hilary⋅Mead, Laura⋅Mead, Laura⋅Wenning, Mary J⋅Wenning, Mary Jo⋅Williams, David A⋅Williams, David A⋅Kapur, Reuben⋅Kapur, Reuben⋅Atkinson, Simon J⋅Atkinson, Simon J⋅Clapp, D. W and Clapp, D Wade
The Journal of clinical investigation, vol. 112, (no. 12), pp. 1851-61, 2003/Dec. | Journal Article
 
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1^sup +/-^ mast cells
Yang, Feng Chun⋅Ingram, David A⋅Chen, Shi⋅Hingtgen, Cynthia M and al, et
Journal of Clinical Investigation, vol. 112, (no. 12), pp. 1851-61, Dec 2003. | Journal Article
1994
Mechanisms of prostacyclin-induced modulation of neuropeptide release from rat sensory neurons grown in culture (Dissertation)
Hingtgen, Cynthia M (1994).