My laboratory is attempting to better understand the molecular and mechanistic basis of the roles of ion channels in human health and disease. In particular, my laboratory’s research aims to study fundamentals of synaptic transmission because improper function and regulation of Na+ and Ca2+ channels and the proteins that regulate them can contribute to epilepsy and neuropathic pain.
Regulation of calcium channels by interacting proteins
CRMP regulation of calcium and sodium channels
Neurofibromatosis, CRMP-2 and calcium channels: a new network in neurofibromatosis type I
Functional analyses of the antiepileptic drug lacosamide and its derivatives on sodium channels and in pain
