131 Publications (Page 2 of 6)
Abstract LB-119: Targeting DNA-PK via small molecule inhibitors of the Ku-DNA interaction
Turchi, John JGavande, NavnathVanderVere-Carozza, PamelaVernon, Tyler and Pawelczak, Katherine
Cancer Research, vol. 77, (no. 13 Supplement), pp. LB-119, 2017-07-01. | Journal Article
Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein–DNA Interaction
Gavande, Navnath SVanderVere-Carozza, PamelaMishra, Akaash KVernon, Tyler LPawelczak, Katherine S and Turchi, John J
Journal of Medicinal Chemistry, vol. 60, (no. 19), pp. 8070, 20171012. | Journal Article
Modulating DNA repair pathways to improve precision genome engineering.
Pawelczak, Katherine SGavande, Navnath SVanderVere-Carozza, Pamela S and Turchi, John J
ACS chemical biology, December 6, 2017. | Journal Article
DNA damage response (DDR) pathway engagement in cisplatin radiosensitization of non-small cell lung cancer.
Sears, Catherine RSears, Catherine RCooney, Sean ACooney, Sean AChin-Sinex, HelenChin-Sinex, HelenMendonca, Marc SMendonca, Marc STurchi, John J and Turchi, John J
DNA repair, vol. 40, pp. 35-46, April 2016. | Journal Article
DNA repair targeted therapy: The past or future of cancer treatment?
Gavande, Navnath SVanderVere-Carozza, Pamela SHinshaw, Hilary DJalal, Shadia ISears, Catherine RPawelczak, Katherine S and Turchi, John J
Pharmacology & therapeutics, vol. 160, pp. 65-83, April 2016. | Journal Article
Abstract C57: Discovery and development of replication protein A (RPA)-DNA interaction inhibitors for cancer chemotherapy
Gavande, NavnathVanderVere-Carozza, Pamela SMishra, Akaash and Turchi, John J
Molecular Cancer Therapeutics, vol. 14, (no. 12 Supplement 2), pp. C57, 2015-12-00. | Journal Article
Abstract C58: Small molecule inhibitors targeting the interaction of xeroderma pigmentosum group A protein with cisplatin-damaged DNA
VanderVere-Carozza, Pamela SGavande, NavnathMishra, Akaash and Turchi, John J
Molecular Cancer Therapeutics, vol. 14, (no. 12 Supplement 2), pp. C58, 2015-12-00. | Journal Article
Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancer.
Mishra, Akaash KDormi, Silvana STurchi, Alaina MWoods, Derek S and Turchi, John J
Biochemical pharmacology, vol. 93, (no. 1), pp. 25-33, January 1, 2015. | Journal Article
Recognition of DNA Termini by the C-Terminal Region of the Ku80 and the DNA-Dependent Protein Kinase Catalytic Subunit.
Woods, Derek SSears, Catherine R and Turchi, John J
PloS one, vol. 10, (no. 5), pp. e0127321, 2015. | Journal Article
Exploring a structural protein-drug interactome for new therapeutics in lung cancer.
Peng, XiaodongPeng, XiaodongPeng, XiaodongWang, FangWang, FangWang, FangLi, LiweiLi, LiweiLi, LiweiBum-Erdene, KhuchtumurBum-Erdene, KhuchtumurBum-Erdene, KhuchtumurXu, DavidXu, DavidXu, DavidWang, BoWang, BoWang, BoSinn, Anthony ASinn, Anthony ASinn, Anthony APollok, Karen EPollok, Karen EPollok, Karen ESandusky, George ESandusky, George ESandusky, George ELi, LangLi, LangLi, LangTurchi, John JTurchi, John JTurchi, John JJalal, Shadia IJalal, Shadia IJalal, Shadia IMeroueh, Samy OMeroueh, Samy O and Meroueh, Samy
Molecular bioSystems, vol. 10, (no. 3), pp. 581-91, 2014/Mar/4. | Journal Article
Testing the metal of ERCC2 in predicting the response to platinum-based therapy.
Turchi, John JWoods, Derek S and VanderVere-Carozza, Pamela
Cancer discovery, vol. 4, (no. 10), pp. 1118-1119, October 2014. | Journal Article
The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer.
Fang, FangMunck, JoanneTang, JessicaTaverna, PietroWang, YinuMiller, David F BPilrose, JayChoy, GavinAzab, MohammadPawelczak, Katherine SVanderVere-Carozza, PamelaWagner, MichaelLyons, JohnMatei, DanielaTurchi, John J and Nephew, Kenneth P
Clinical cancer research : an official journal of the American Association for Cancer Research, vol. 20, (no. 24), pp. 6504-6516, December 15, 2014. | Journal Article
Unraveling the complexities of DNA-dependent protein kinase autophosphorylation.
Neal, Jessica ASugiman-Marangos, SeijiVanderVere-Carozza, PamelaWagner, MikeTurchi, JohnLees Miller, Susan PJunop, Murray S and Meek, Katheryn
Molecular and cellular biology, vol. 34, (no. 12), pp. 2162-75, 2014/Jun. | Journal Article
Abstract 4623: The novel, small molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer
Tang, JessicaTang, JessicaFang, FangFang, FangWang, YinuWang, YinuTaverna, PietroTaverna, PietroMiller, David F.BMiller, David F.BChoy, GavinChoy, GavinAzab, MohammadAzab, MohammadMatei, DanielaMatei, DanielaPawelczak, Katherine SPawelczak, Katherine SVanderVere-Carozza, PamelaVanderVere-Carozza, PamelaWagner, MichaelWagner, MichaelTurchi, John JTurchi, John JNephew, Kenneth P and Nephew, Kenneth P
Cancer Research, vol. 73, (no. 8 Supplement), pp. 4623, 2013-04-15. | Journal Article
Chemotherapy induced DNA damage response: convergence of drugs and pathways.
Woods, Derek and Turchi, John J
Cancer biology & therapy, vol. 14, (no. 5), pp. 379-89, 2013/May. | Journal Article
Extracellular tissue transglutaminase activates noncanonical NF-κB signaling and promotes metastasis in ovarian cancer.
Yakubov, BakhtiyorYakubov, BakhtiyorChelladurai, BhadraniChelladurai, BhadraniSchmitt, JordanSchmitt, JordanEmerson, RobertEmerson, RobertTurchi, John JTurchi, JohnMatei, Daniela and Matei, Daniela
Neoplasia (New York, N.Y.), vol. 15, (no. 6), pp. 609-19, 2013/Jun. | Journal Article
Extracellular Tissue Transglutaminase Activates Noncanonical NF-κB Signaling and Promotes Metastasis in Ovarian Cancer12
Yakubov, BakhtiyorYakubov, BakhtiyorChelladurai, BhadraniChelladurai, BhadraniSchmitt, JordanSchmitt, JordanEmerson, RobertEmerson, RobertTurchi, John JTurchi, John JMatei, Daniela and Matei, Daniela
Neoplasia (New York, N.Y.), vol. 15, (no. 6), pp. 619, 2013-06-01. | Journal Article
Targeting SHP2 for EGFR inhibitor resistant non-small cell lung carcinoma.
Xu, JieZeng, Li-FanShen, WeihuaTurchi, John J and Zhang, Z. F
Biochemical and biophysical research communications, vol. 439, (no. 4), pp. 586-90, 2013/Oct/4. | Journal Article
Abstract 4753: Targeting nucleotide excision repair: Chemical synthetic lethality and biology-based combination therapy
Turchi, John JLee, JiyoonHendricks, JeremiahNeher, Tracy M and Fitch, Richard W
Cancer Research, vol. 72, (no. 8 Supplement), pp. 4753, 2012-04-15. | Journal Article
Complex cisplatin-double strand break (DSB) lesions directly impair cellular non-homologous end-joining (NHEJ) independent of downstream damage response (DDR) pathways.
Sears, Catherine R and Turchi, John J
The Journal of biological chemistry, vol. 287, (no. 29), pp. 24263-72, 2012/Jul/13. | Journal Article
Multiple protein-protein interactions within the DNA-PK complex are mediated by the C-terminus of Ku 80.
Bennett, Sara MWoods, Derek SPawelczak, Katherine S and Turchi, John J
International journal of biochemistry and molecular biology, vol. 3, (no. 1), pp. 36-45, 2012. | Journal Article
Abstract 1551: Soluble tissue transglutaminase modulates cellular adhesion to matrix and peritoneal metastasis in ovarian cancer
Yakubov, BakhtiyorYakubov, BakhtiyorChelladurai, BhadraniChelladurai, BhadraniTurchi, JohnTurchi, JohnMatei, Daniela E and Matei, Daniela E
Cancer Research, vol. 71, (no. 8 Supplement), pp. 1551, 2011-04-15. | Journal Article
Abstract 2320: In vivo characterization of small molecule inhibitors of replication protein A: Implications for cancer therapy
Neher, Tracy MNeher, Tracy MBodenmiller, Diane MBodenmiller, Diane MTurchi, John JTurchi, John JJalal, Shadia I and Jalal, Shadia I
Cancer Research, vol. 71, (no. 8 Supplement), pp. 2320, 2011-04-15. | Journal Article
Coordination of DNA-PK Activation and Nuclease Processing of DNA Termini in NHEJ
Pawelczak, KSBennett, SM and Turchi, John J
Antioxidants and Redox Signaling, vol. 14, (no. 12), pp. 2531-2543, 2011. | Journal Article
Current advances in DNA repair: regulation of enzymes and pathways involved in maintaining genomic stability.
Neher, Tracy M and Turchi, John J
Antioxidants & redox signaling, vol. 14, (no. 12), pp. 2461-4, 2011/Jun/15. | Journal Article