129 Publications (Page 1 of 6)
2023
Data from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Ku–DNA binding inhibitors modulate the DNA damage response in response to DNA double-strand breaks. NAR Cancer
. | Journal Article
Supplementary Figure S1 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S1 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S2 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S2 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S3 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S3 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S4 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S4 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S5 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S5 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S6 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
Supplementary Figure S6 from Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A Is Mediated by Replication Protein A in Ovarian Cancer
2022
Synthesis and Biological Evaluation of Cardiac Glycosides for Cancer Therapy by Targeting the DNA Damage Response. ChemMedChem
2021
OB-Folds and Genome Maintenance: Targeting Protein–DNA Interactions for Cancer TherapyPar, Sui⋅Vaides, Sofia⋅Vaides, Sofia⋅VanderVere-Carozza, Pamela S⋅VanderVere-Carozza, Pamela S⋅Pawelczak, Katherine S⋅Pawelczak, Katherine S⋅Stewart, Jason⋅Stewart, Jason⋅Turchi, John J and Turchi, John JCancers, vol. 13, (no. 13), 2021.
| Journal Article
2020
Platinum-Induced Ubiquitination of Phosphorylated H2AX by RING1A is Mediated by Replication Protein A in Ovarian Cancer
Sriramkumar, Shruthi⋅S, Sriramkumar⋅Matthews, Timothy D.⋅TD, Matthews⋅Ghobashi, Ahmed H.⋅AH, Ghobashi⋅Miller, Samuel A.⋅SA, Miller⋅VanderVere-Carozza, Pamela S.⋅PS, VanderVere-Carozza⋅KS, Pawelczak⋅Pawelczak, Katherine S.⋅KP, Nephew⋅Nephew, Kenneth P.⋅Turchi, John J⋅JJ, Turchi⋅O’Hagan, Heather M. and HM, O’Hagan
Molecular Cancer Research, pp. molcanres.0396.2020. | Journal Article
Structure-Guided Optimization of Replication Protein A (RPA)–DNA Interaction Inhibitors
Gavande, Navnath S⋅VanderVere-Carozza, Pamela S⋅Pawelczak, Katherine S⋅Vernon, Tyler L⋅Jordan, Matthew R and Turchi, John J
ACS Medicinal Chemistry Letters, 2020-01-09. | Journal Article
2019
Small-Molecule Inhibitor Screen for DNA Repair Proteins
Turchi, John J and VanderVere-Carozza, Pamela S
Methods in molecular biology (Clifton, N.J.), vol. 1999, pp. 217, 2019-00-00. | Journal Article
2018
Abstract 2829: Targeting the DNA damage response and DNA-PK signaling via small molecule Ku inhibitors
Turchi, John J⋅Gavande, Navnath S⋅VanderVere-Carozza, Pamela S⋅Vernon, Tyler and Pawelczak, Katherine S
Cancer Research, vol. 78, (no. 13 Supplement), pp. 2829, 2018-07-01. | Journal Article
Characterization of Thermally Activated Metalloenediyne Cytotoxicity in Human Melanoma CellsKeller, Eric J⋅Keller, Eric⋅Keller, Eric J⋅Keller, Eric J⋅Porter, Meghan⋅Porter, Meghan⋅Porter, Meghan⋅Porter, Meghan⋅Garrett, Joy⋅Garrett, Joy E⋅Garrett, Joy E⋅Garrett, Joy E⋅Varie, Meredith⋅Varie, Meredith⋅Varie, Meredith⋅Varie, Meredith⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen⋅Turchi, John J⋅Turchi, John⋅Turchi, John J⋅Turchi, John J⋅Zaleski, Jeffrey⋅Zaleski, Jeffrey M⋅Zaleski, Jeffrey M⋅Zaleski, Jeffrey M⋅Dynlacht, Joseph R⋅Dynlacht, Joseph R⋅Dynlacht, Joseph R and Dynlacht, JosephRadiation research, vol. 190, (no. 2), pp. 116, 2018-08-00.
| Journal Article
2017
Abstract 1416: Development of small molecule inhibitors for cancer therapy by targeting RPA and XPA nucleotide excision repair proteins
Gavande, Navnath S⋅VanderVere-Carozza, Pamela S⋅Vernon, Tyler L⋅Pawelczak, Katherine and Turchi, John J
Cancer Research, vol. 77, (no. 13 Supplement), pp. 1416, 2017-07-01. | Journal Article
Abstract B34: Development of novel small molecule inhibitors targeting DNA repair proteins
Pawelczak, Katherine S⋅Gavande, Navnath⋅VanderVere-Carozza, Pamela and Turchi, John
Molecular Cancer Research, vol. 15, (no. 4 Supplement), pp. B34, 2017-04-00. | Journal Article
Abstract LB-119: Targeting DNA-PK via small molecule inhibitors of the Ku-DNA interaction
Turchi, John J⋅Gavande, Navnath⋅VanderVere-Carozza, Pamela⋅Vernon, Tyler and Pawelczak, Katherine
Cancer Research, vol. 77, (no. 13 Supplement), pp. LB-119, 2017-07-01. | Journal Article
Design and Structure-Guided Development of Novel Inhibitors of the Xeroderma Pigmentosum Group A (XPA) Protein–DNA Interaction
Gavande, Navnath S⋅VanderVere-Carozza, Pamela⋅Mishra, Akaash K⋅Vernon, Tyler L⋅Pawelczak, Katherine S and Turchi, John J
Journal of Medicinal Chemistry, vol. 60, (no. 19), pp. 8070, 20171012. | Journal Article