131 Publications (Page 4 of 6)
2006
Pre-Steady-State Binding of Damaged DNA by XPC-hHR23B Reveals a Kinetic Mechanism for Damage DiscriminationTrego, KS and Turchi, John JBiochemistry (Washington), vol. 45, (no. 6), pp. 1961-1969, 2006.
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2005
Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining.Boeckman, Heather J⋅Trego, Kelly S and Turchi, John JMolecular cancer research : MCR, vol. 3, (no. 5), pp. 277-85, 2005/May.
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Differential activation of DNA-PK based on DNA strand orientation and sequence biasPawelczak, Katherine S⋅Andrews, Brooke J and Turchi, John JNucleic Acids Research, vol. 33, (no. 1), pp. 152-61, 2005.
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DNA adduct-targeted mutagenicity of tamoxifen, a drug used for chemotherapy and chemoprevention of breast cancer, as a function of its genotoxicity in the cII transgene in Big Blue mouse embryonic fibroblasts is investigated. Data suggests a proficient metabolic activation of tamoxifen in human liver and an inefficient activation and efficient detoxification of tamoxifen in human endometriumPatrick, Steve⋅Oakley, Greg⋅Dixon, Kathleen and Turchi, JohnBiochemistry, vol. 44, (no. 23), pp. 8438, 20050614.
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DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.Nuss, Jonathan E⋅Patrick, Steve M⋅Oakley, Gregory G⋅Alter, Gerald M⋅Robison, Jacob G⋅Dixon, Kathleen and Turchi, John JBiochemistry, vol. 44, (no. 23), pp. 8428-37, 2005/Jun/14.
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DNA Damage Induced Hyperphosphorylation of Replication Protein A. 2. Characterization of DNA Binding Activity, Protein Interactions, and Activity in DNA Replication and RepairPatrick, SM⋅Oakley, Gregory G⋅Dixon, Kathleen and Turchi, John JBiochemistry (Washington), vol. 44, (no. 23), pp. 8438-8448, 2005.
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Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forksZheng, Li⋅Zhou, Mian⋅Chai, Qing⋅Parrish, Jay⋅Xue, Ding⋅Patrick, Steve M⋅Turchi, John J⋅Yannone, Steven M⋅Chen, David and Shen, BinghuiEMBO Reports, vol. 6, (no. 1), pp. 83-89, 2005.
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2004
Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2Lillard-Wetherell, Kate⋅Machwe, Amrita⋅Langland, Gregory T⋅Combs, Kelly A⋅Behbehani, Gregory K⋅Schonberg, Steven A⋅German, James⋅Turchi, John J⋅Orren, David K and Groden, JoannaHuman Molecular Genetics, vol. 13, (no. 17), pp. 1919-1932, 2004.
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Development of a high-throughput screen for inhibitors of replication protein A and its role in nucleotide excision repair.Andrews, Brooke J and Turchi, John JMolecular cancer therapeutics, vol. 3, (no. 4), pp. 385-91, 2004/Apr.
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Interaction and stimulation of human FEN-1 nuclease activities by heterogeneous nuclear ribonucleoprotein A1 in alpha-segment processing during Okazaki fragment maturation.Chai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John J and Shen, BinghuiBiochemistry, vol. 42, (no. 51), pp. 15045-52, 2003/Dec/30.
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Interaction and Stimulation of Human FEN-1 Nuclease Activities by Heterogeneous Nuclear Ribonucleoprotein A1 in α-Segment Processing during Okazaki Fragment MaturationChai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John J and Shen, BinghuiBiochemistry, vol. 42, (no. 51), pp. 15052, 20031230.
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Interaction and stimulation of human FEN-I nuclease activities by heterogeneous ribonucleoprotein A1 in alpha-segment processing during Okazaki fragment maturationChai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John and Shen, BinghuiBiochemistry, vol. 42, (no. 51), pp. 15045, 20031230.
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RPA Phosphorylation in Mitosis Alters DNA Binding and Protein-Protein InteractionsOakley, Gregory G⋅Patrick, SM⋅Yao, J.⋅Carty, Michael⋅Turchi, John J and Dixon, KathleenBiochemistry (Washington), vol. 42, (no. 11), pp. 3255-3264, 2003.
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2002
Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein ARamilo, C.⋅Gu, Liya⋅Guo, S.⋅Zhang, X.⋅Patrick, SM⋅Turchi, John J and Li, Guo MinMolecular and Cellular Biology, vol. 22, (no. 7), pp. 2037-2046, 2002.
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Strand-specific binding of RPA and XPA to damaged duplex DNA.Hermanson-Miller, Ingrid L and Turchi, John JBiochemistry, vol. 41, (no. 7), pp. 2402-8, 2002/Feb/19.
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Xeroderma Pigmentosum Complementation Group A Protein (XPA) Modulates RPA-DNA Interactions via Enhanced Complex Stability and Inhibition of Strand Separation ActivityPatrick, SM and Turchi, John JJournal of Biological Chemistry, vol. 277, (no. 18), pp. 16096-16101, 2002.
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2001
DNA-Dependent Protein Kinase in Apoptosis.Turchi, John JMethods in molecular medicine, vol. 39, pp. 693-700, 2001.
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Stopped-flow Kinetic Analysis of Replication Protein A-binding DNAPatrick, Steve M and Turchi, John JJournal of Biological Chemistry, vol. 276, (no. 25), pp. 22637, 2001-06-22.
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Stopped-flow kinetic analysis of replication protein A-binding DNA: damage recognition and affinity for single-stranded DNA reveal differential contributions of k(on) and k(off) rate constants.Patrick, S M and Turchi, John JThe Journal of biological chemistry, vol. 276, (no. 25), pp. 22630-7, 2001/Jun/22.
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Stopped-flow Kinetic Analysis of Replication Protein A- binding DNA: Damage Recognition and Affinity for Single-Stranded DNA Reveal Differential Contributions of k sub(on) and k sub(off) Rate ConstantsPatrick, SM and Turchi, John JJournal of Biological Chemistry, vol. 276, (no. 25), pp. 22630-22637, 2001.
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TRF1 inhibitis telomere C-strand DNA synthesis in vitroSmucker, Elizabeth and Turchi, JohnBiochemistry, vol. 40, (no. 8), pp. 2426, 20010227.
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TRF1 Inhibits Telomere C-Strand DNA Synthesis in VitroSmucker, EJ and Turchi, John JBiochemistry (Washington), vol. 40, (no. 8), pp. 2426-2432, 2001.
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2000
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PKTurchi, John J⋅Henkels, Karen M and Zhou, YunNucleic Acids Research, vol. 28, (no. 23), pp. 4634, Dec 1, 2000.
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Overexpression and purification of human XPA using a baculovirus expression system.Hermanson, I L and Turchi, John JProtein expression and purification, vol. 19, (no. 1), pp. 1-11, 2000/Jun.
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