130 Publications (Page 4 of 6)
2005
Cisplatin sensitizes cancer cells to ionizing radiation via inhibition of nonhomologous end joining.
Boeckman, Heather J⋅Trego, Kelly S and Turchi, John J
Molecular cancer research : MCR, vol. 3, (no. 5), pp. 277-85, 2005/May. | Journal Article
 
Differential activation of DNA-PK based on DNA strand orientation and sequence bias
Pawelczak, Katherine S⋅Andrews, Brooke J and Turchi, John J
Nucleic Acids Research, vol. 33, (no. 1), pp. 152-61, 2005. | Journal Article
 
DNA adduct-targeted mutagenicity of tamoxifen, a drug used for chemotherapy and chemoprevention of breast cancer, as a function of its genotoxicity in the cII transgene in Big Blue mouse embryonic fibroblasts is investigated. Data suggests a proficient metabolic activation of tamoxifen in human liver and an inefficient activation and efficient detoxification of tamoxifen in human endometrium
Patrick, Steve⋅Oakley, Greg⋅Dixon, Kathleen and Turchi, John
Biochemistry, vol. 44, (no. 23), pp. 8438, 20050614. | Journal Article
 
DNA damage induced hyperphosphorylation of replication protein A. 1. Identification of novel sites of phosphorylation in response to DNA damage.
Nuss, Jonathan E⋅Patrick, Steve M⋅Oakley, Gregory G⋅Alter, Gerald M⋅Robison, Jacob G⋅Dixon, Kathleen and Turchi, John J
Biochemistry, vol. 44, (no. 23), pp. 8428-37, 2005/Jun/14. | Journal Article
 
DNA Damage Induced Hyperphosphorylation of Replication Protein A. 2. Characterization of DNA Binding Activity, Protein Interactions, and Activity in DNA Replication and Repair
Patrick, SM⋅Oakley, Gregory G⋅Dixon, Kathleen and Turchi, John J
Biochemistry (Washington), vol. 44, (no. 23), pp. 8438-8448, 2005. | Journal Article
 
Novel function of the flap endonuclease 1 complex in processing stalled DNA replication forks
Zheng, Li⋅Zhou, Mian⋅Chai, Qing⋅Parrish, Jay⋅Xue, Ding⋅Patrick, Steve M⋅Turchi, John J⋅Yannone, Steven M⋅Chen, David and Shen, Binghui
EMBO Reports, vol. 6, (no. 1), pp. 83-89, 2005. | Journal Article
2004
Association and regulation of the BLM helicase by the telomere proteins TRF1 and TRF2
Lillard-Wetherell, Kate⋅Machwe, Amrita⋅Langland, Gregory T⋅Combs, Kelly A⋅Behbehani, Gregory K⋅Schonberg, Steven A⋅German, James⋅Turchi, John J⋅Orren, David K and Groden, Joanna
Human Molecular Genetics, vol. 13, (no. 17), pp. 1919-1932, 2004. | Journal Article
 
Development of a high-throughput screen for inhibitors of replication protein A and its role in nucleotide excision repair.
Andrews, Brooke J and Turchi, John J
Molecular cancer therapeutics, vol. 3, (no. 4), pp. 385-91, 2004/Apr. | Journal Article
2003
Behavior of T7 RNA Polymerase and Mammalian RNA Polymerase II at Site-specific Cisplatin Adducts in the Template DNA
Tornaletti, Silvia⋅Patrick, Sm⋅Turchi, John J and Hanawalt, Philip
Journal of Biological Chemistry, vol. 278, (no. 37), pp. 35791-35797, 2003. | Journal Article
 
Interaction and stimulation of human FEN-1 nuclease activities by heterogeneous nuclear ribonucleoprotein A1 in alpha-segment processing during Okazaki fragment maturation.
Chai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John J and Shen, Binghui
Biochemistry, vol. 42, (no. 51), pp. 15045-52, 2003/Dec/30. | Journal Article
 
Interaction and Stimulation of Human FEN-1 Nuclease Activities by Heterogeneous Nuclear Ribonucleoprotein A1 in α-Segment Processing during Okazaki Fragment Maturation
Chai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John J and Shen, Binghui
Biochemistry, vol. 42, (no. 51), pp. 15052, 20031230. | Journal Article
 
Interaction and stimulation of human FEN-I nuclease activities by heterogeneous ribonucleoprotein A1 in alpha-segment processing during Okazaki fragment maturation
Chai, Qing⋅Zheng, Li⋅Zhou, Mian⋅Turchi, John and Shen, Binghui
Biochemistry, vol. 42, (no. 51), pp. 15045, 20031230. | Journal Article
 
RPA Phosphorylation in Mitosis Alters DNA Binding and Protein-Protein Interactions
Oakley, Gregory G⋅Patrick, SM⋅Yao, J.⋅Carty, Michael⋅Turchi, John J and Dixon, Kathleen
Biochemistry (Washington), vol. 42, (no. 11), pp. 3255-3264, 2003. | Journal Article
2002
Partial Reconstitution of Human DNA Mismatch Repair In Vitro: Characterization of the Role of Human Replication Protein A
Ramilo, C.⋅Gu, Liya⋅Guo, S.⋅Zhang, X.⋅Patrick, SM⋅Turchi, John J and Li, Guo Min
Molecular and Cellular Biology, vol. 22, (no. 7), pp. 2037-2046, 2002. | Journal Article
 
Strand-specific binding of RPA and XPA to damaged duplex DNA.
Hermanson-Miller, Ingrid L and Turchi, John J
Biochemistry, vol. 41, (no. 7), pp. 2402-8, 2002/Feb/19. | Journal Article
 
Xeroderma Pigmentosum Complementation Group A Protein (XPA) Modulates RPA-DNA Interactions via Enhanced Complex Stability and Inhibition of Strand Separation Activity
Patrick, SM and Turchi, John J
Journal of Biological Chemistry, vol. 277, (no. 18), pp. 16096-16101, 2002. | Journal Article
2001
DNA-Dependent Protein Kinase in Apoptosis.
Turchi, John J
Methods in molecular medicine, vol. 39, pp. 693-700, 2001. | Journal Article
 
Stopped-flow Kinetic Analysis of Replication Protein A-binding DNA
Patrick, Steve M and Turchi, John J
Journal of Biological Chemistry, vol. 276, (no. 25), pp. 22637, 2001-06-22. | Journal Article
 
Stopped-flow kinetic analysis of replication protein A-binding DNA: damage recognition and affinity for single-stranded DNA reveal differential contributions of k(on) and k(off) rate constants.
Patrick, S M and Turchi, John J
The Journal of biological chemistry, vol. 276, (no. 25), pp. 22630-7, 2001/Jun/22. | Journal Article
 
Stopped-flow Kinetic Analysis of Replication Protein A- binding DNA: Damage Recognition and Affinity for Single-Stranded DNA Reveal Differential Contributions of k sub(on) and k sub(off) Rate Constants
Patrick, SM and Turchi, John J
Journal of Biological Chemistry, vol. 276, (no. 25), pp. 22630-22637, 2001. | Journal Article
 
TRF1 inhibitis telomere C-strand DNA synthesis in vitro
Smucker, Elizabeth and Turchi, John
Biochemistry, vol. 40, (no. 8), pp. 2426, 20010227. | Journal Article
 
TRF1 Inhibits Telomere C-Strand DNA Synthesis in Vitro
Smucker, EJ and Turchi, John J
Biochemistry (Washington), vol. 40, (no. 8), pp. 2426-2432, 2001. | Journal Article
2000
Cisplatin-DNA adducts inhibit translocation of the Ku subunits of DNA-PK
Turchi, John J⋅Henkels, Karen M and Zhou, Yun
Nucleic Acids Research, vol. 28, (no. 23), pp. 4634, Dec 1, 2000. | Journal Article
 
Overexpression and purification of human XPA using a baculovirus expression system.
Hermanson, I L and Turchi, John J
Protein expression and purification, vol. 19, (no. 1), pp. 1-11, 2000/Jun. | Journal Article
 
Physiological functions of protein kinase inhibitors.
Turchi, John J and Ho, M
EXS, vol. 89, pp. 109-21, 2000. | Journal Article