Expertise

Our research is focused on determining the molecular mechanism by which cisplatin imparts its efficacy. We are involved in the identification and development of agents that target specific proteins involved in cisplatin metabolism with the goal of enhancing cisplatin activity in tumors and cancer types that typically do not respond well to cisplatin. We are also involved in research geared towards understanding the interaction of cisplatin and ionizing radiation and how this treatment regimen influences DNA repair pathways.

Past Affiliations

Professor, Division of Hematology and Oncology, Department of Medicine, Indiana University School of Medicine

Associate Professor, Department of Biochemistry and Molecular Biology, Boonshoft School of Medicine, Wright State University (past)

Professor, Department of Biochemistry and Molecular Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Associate Professor, Department of Biochemistry and Molecular Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Professor, Department of Biochemistry and Molecular Biology, Indiana University-Purdue University Indianapolis, School of Medicine (past)

Communities
Biochemistry, Molecular Biology, Oncology, Oncology, Hematology, Cellular Biochemistry, Molecular Biochemistry
Degrees
PhD, University of Missouri-Columbia, Biochemistry, 1990
BS, Clemson University, Biochemistry, 1985
Associations
American Association for Cancer Research
American Association for the Advancement of Science
American Society for Biochemistry and Molecular Biology