19 Publications
2014
Soypeptide lunasin in cytokine immunotherapy for lymphoma.
Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Lewis, David⋅Lewis, David⋅Lewis, David⋅Tung, Chun-Yu⋅Tung, Chun-Yu⋅Tung, Chun-Yu⋅Han, Ling⋅Han, Ling⋅Han, Ling⋅Henriquez, Sarah M⋅Henriquez, Sarah⋅Henriquez, Sarah⋅Voiles, Larry⋅Voiles, Larry⋅Voiles, Larry⋅Lupov, Ivan P⋅Lupov, Ivan⋅Lupov, Ivan⋅Pelloso, David⋅Pelloso, David⋅Pelloso, David⋅Sinn, Anthony⋅Sinn, Anthony L⋅Sinn, Anthony⋅Pollok, Karen⋅Pollok, Karen E⋅Pollok, Karen⋅de Lumen, Ben O⋅de Lumen, Ben⋅de Lumen, Ben⋅Li, Fang⋅Li, Fang⋅Li, Fang⋅Blum, Janice⋅Blum, Janice S⋅Blum, Janice⋅Srivastava, Shivani⋅Srivastava, Shivani⋅Srivastava, Shivani⋅Robertson, Michael⋅Robertson, Michael J and Robertson, Michael
Cancer immunology, immunotherapy : CII, vol. 63, (no. 3), pp. 283-95, 2014/Mar. | Journal Article
2011
The transcription factor PU.1 regulates γδ T cell homeostasis.
Jabeen, Rukhsana⋅Chang, Hua-Chen⋅Goswami, Ritobrata⋅Nutt, Stephen L and Kaplan, Mark H
PloS one, vol. 6, (no. 7), pp. e22189, 2011. | Journal Article
2010
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Chang, Hua-Chen⋅Chang, Hua-Chen⋅Sehra, Sarita⋅Sehra, Sarita⋅Goswami, Ritobrata⋅Goswami, Ritobrata⋅Yao, Weiguo⋅Yao, Weiguo⋅Yu, Qing⋅Yu, Qing⋅Stritesky, Gretta L⋅Stritesky, Gretta L⋅Jabeen, Rukhsana⋅Jabeen, Rukhsana⋅McKinley, Carl⋅McKinley, Carl⋅Ahyi, Ayele-Nati⋅Ahyi, Ayele-Nati⋅Han, Ling⋅Han, Ling⋅Nguyen, Evelyn T⋅Nguyen, Evelyn T⋅Robertson, Michael J⋅Robertson, Michael J⋅Perumal, Narayanan B⋅Perumal, Narayanan B⋅Tepper, Robert S⋅Tepper, Robert S⋅Nutt, Stephen L⋅Nutt, Stephen L⋅Kaplan, Mark H and Kaplan, Mark H
Nature immunology, vol. 11, (no. 6), pp. 527-34, 2010/Jun. | Journal Article
2009
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.
Ahyi, Ayele-Nati N⋅Chang, Hua-Chen⋅Dent, Alexander L⋅Nutt, Stephen L and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 183, (no. 3), pp. 1598-606, 2009/Aug/1. | Journal Article
 
Impaired development of human Th1 cells in patients with deficient expression of STAT4.
Chang, Hua-Chen⋅Han, Ling⋅Goswami, Ritobrata⋅Nguyen, Evelyn T⋅Pelloso, David⋅Robertson, Michael J and Kaplan, Mark H
Blood, vol. 113, (no. 23), pp. 5887-90, 2009/Jun/4. | Journal Article
 
PU.1 regulates TCR expression by modulating GATA-3 activity.
Chang, Hua-Chen⋅Han, Ling⋅Jabeen, Rukhsana⋅Carotta, Sebastian⋅Nutt, Stephen L and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 183, (no. 8), pp. 4887-94, 2009/Oct/15. | Journal Article
 
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells
O'Malley, John T⋅Sehra, Sarita⋅Thieu, Vivian T⋅Yu, Qing⋅Chang, Hua-Chen⋅Stritesky, Gretta L⋅Nguyen, Evelyn T⋅Mathur, Anubhav N⋅Levy, David E and Kaplan, Mark H
Immunology, vol. 127, (no. 4), pp. 587-595, 2009. | Journal Article
2008
Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination.
Thieu, Vivian T⋅Thieu, Vivian T⋅Yu, Qing⋅Yu, Qing⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Yeh, Norman⋅Yeh, Norman⋅Nguyen, Evelyn T⋅Nguyen, Evelyn T⋅Sehra, Sarita⋅Sehra, Sarita⋅Kaplan, Mark H and Kaplan, Mark H
Immunity, vol. 29, (no. 5), pp. 679-90, 2008/Nov/14. | Journal Article
 
STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.
O'Malley, John T⋅Eri, Rajaraman D⋅Stritesky, Gretta L⋅Mathur, Anubhav N⋅Chang, Hua-Chen⋅Hogen Esch, Harm⋅Hogenesch, Harm⋅Srinivasan, Mythily and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 7), pp. 5062-70, 2008/Oct/1. | Journal Article
 
Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation.
Yu, Qing⋅Chang, Hua-Chen⋅Ahyi, Ayele-Nati N and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 5), pp. 3346-52, 2008/Sep/1. | Journal Article
 
Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.
Mann, Brandon A⋅Huang, Julia H⋅Li, Ping⋅Chang, Hua-Chen⋅Slee, Roger B⋅O'Sullivan, Audrey⋅Anita, Mathur⋅Yeh, Norman⋅Klemsz, Michael J⋅Brutkiewicz, Randy R⋅Blum, Janice S and Kaplan, Mark H
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, vol. 28, (no. 6), pp. 367-80, 2008/Jun. | Journal Article
2007
Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
Li, Yu⋅Li, Yu⋅Li, Yu⋅Yan, Jingliang⋅Yan, Jingliang⋅Yan, Jingliang⋅De, Pradip⋅De, Pradip⋅De, Pradip⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Chang, Hua-Chen⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Yamauchi, Akira⋅Christopherson, Kent⋅Christopherson, Kent W⋅Christopherson, Kent⋅Paranavitana, Nivanka⋅Paranavitana, Nivanka C⋅Paranavitana, Nivanka⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Peng, Xiaodong⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Kim, Chaekyun⋅Munugulavadla, Veerendra⋅Munugulavadla, Veerendra⋅Munugulavadla, Veerendra⋅Kapur, Reuben⋅Kapur, Reuben⋅Kapur, Reuben⋅Chen, Hanying⋅Chen, Hanying⋅Chen, Hanying⋅Shou, Weinian⋅Shou, Weinian⋅Shou, Weinian⋅Stone, James⋅Stone, James C⋅Stone, James⋅Kaplan, Mark H⋅Kaplan, Mark⋅Kaplan, Mark⋅Dinauer, Mary⋅Dinauer, Mary C⋅Dinauer, Mary⋅Durden, Donald⋅Durden, Donald⋅Durden, Donald L⋅Quilliam, Lawrence⋅Quilliam, Lawrence and Quilliam, Lawrence A
Journal of Immunology, vol. 179, (no. 12), pp. 8322-8331, 2007. | Journal Article
 
Stat3 and Stat4 direct development of IL-17-secreting Th cells.
Mathur, Anubhav N⋅Chang, Hua-Chen⋅Zisoulis, Dimitrios G⋅Stritesky, Gretta L⋅Yu, Qing⋅O'Malley, John T⋅Kapur, Reuben⋅Levy, David E⋅Kansas, Geoffrey S and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 178, (no. 8), pp. 4901-7, 2007/Apr/15. | Journal Article
2006
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.
Mathur, Anubhav N⋅Chang, Hua-Chen⋅Zisoulis, Dimitrios G⋅Kapur, Reuben⋅Belladonna, Maria L⋅Kansas, Geoffrey S and Kaplan, Mark H
Blood, vol. 108, (no. 5), pp. 1595-601, 2006/Sep/1. | Journal Article
2005
PU.1 expression delineates heterogeneity in primary Th2 cells.
Chang, Hua-Chen⋅Zhang, Shangming⋅Thieu, Vivian T⋅Slee, Roger B⋅Bruns, Heather A⋅Laribee, R N⋅Klemsz, Michael J and Kaplan, Mark H
Immunity, vol. 22, (no. 6), pp. 693-703, 2005/Jun. | Journal Article
2004
STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
O'Sullivan, Audrey⋅Chang, Hua-Chen⋅Yu, Qing and Kaplan, Mark H
The Journal of biological chemistry, vol. 279, (no. 8), pp. 7339-45, 2004/Feb/20. | Journal Article
2003
Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.
Kaplan, Mark H⋅Chang, Hua-Chen⋅Cooper, Scott⋅Lee, Younghee and Broxmeyer, Hal E
Journal of hematotherapy & stem cell research. , vol. 12, (no. 4), pp. 401-8, 2003/Aug. | Journal Article
 
STAT4 requires the N-terminal domain for efficient phosphorylation.
Chang, Hua-Chen⋅Zhang, Shangming⋅Oldham, India⋅Naeger, Lisa⋅Hoey, Timothy and Kaplan, Mark H
The Journal of biological chemistry, vol. 278, (no. 34), pp. 32471-7, 2003/Aug/22. | Journal Article
2002
Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation.
Chang, Hua-Chen⋅Zhang, Shangming and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 169, (no. 8), pp. 4124-8, 2002/Oct/15. | Journal Article