121 Publications (Page 2 of 5)
2019
HIV-Nef Protein Transfer to Endothelial Cells Requires Rac1 Activation and Leads to Endothelial Dysfunction Implications for Statin Treatment in HIV Patients
Chelvanambi, Sarvesh⋅Chelvanambi, Sarvesh⋅Chelvanambi, Sarvesh⋅Chelvanambi, Sarvesh⋅Gupta, Samir⋅Gupta, Samir⋅Gupta, Samir⋅Gupta, Samir⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Ellis, Bradley⋅Ellis, Bradley⋅Ellis, Bradley⋅Ellis, Bradley⋅Maier, Bernhard⋅Maier, Bernhard⋅Maier, Bernhard⋅Maier, Bernhard⋅Colbert, Tyler⋅Colbert, Tyler⋅Colbert, Tyler⋅Colbert, Tyler⋅Kuriakose, Jithin⋅Kuriakose, Jithin⋅Kuriakose, Jithin⋅Kuriakose, Jithin⋅Zorlutuna, Pinar⋅Zorlutuna, Pinar⋅Zorlutuna, Pinar⋅Zorlutuna, Pinar⋅Jolicoeur, Paul⋅Jolicoeur, Paul⋅Jolicoeur, Paul⋅Jolicoeur, Paul⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Clauss, Matthias⋅Clauss, Matthias⋅Clauss, Matthias and Clauss, Matthias
Circulation Research, vol. 125, (no. 9), pp. 820, 2019-October-11. | Journal Article
 
Long-Term Diabetic Microenvironment Augments the Decay Rate of Capsaicin-Induced Currents in Mouse Dorsal Root Ganglion Neurons
Chen, Xingjuan⋅Chen, Xingjuan⋅Duan, Yaqian⋅Duan, Yaqian⋅Riley, Ashley M⋅Riley, Ashley M⋅Welch, Megan A⋅Welch, Megan A⋅White, Fletcher A⋅White, Fletcher A⋅Grant, Maria B⋅Grant, Maria B⋅Obukhov, Alexander G and Obukhov, Alexander G
Molecules, vol. 24, (no. 4), 2019. | Journal Article
 
The TRPC6 inhibitor, larixyl acetate, is effective in protecting against traumatic brain injury-induced systemic endothelial dysfunction
Chen, Xingjuan⋅Chen, Xingjuan⋅Taylor-Nguyen, Natalie N⋅Taylor-Nguyen, Natalie N⋅Riley, Ashley M⋅Riley, Ashley M⋅Herring, B Paul⋅Herring, B Paul⋅White, Fletcher A⋅White, Fletcher A⋅Obukhov, Alexander G and Obukhov, Alexander G
Journal of neuroinflammation, vol. 16, (no. 1), pp. 21, 2019-Jan-31. | Journal Article
2018
Abstract 17112: Transgenic Endothelial-Specific HIV-Nef Expression Induces Pulmonary Hypertension and Systemic Vascular Dysfunction, Which Can Be Reverted by Treatment With Statin
Bogatcheva, Natalia⋅Bogatcheva, Natalia⋅Bogatcheva, Natalia⋅Chelvanambi, Sarvesh⋅Chelvanambi, Sarvesh⋅Chelvanambi, Sarvesh⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Clauss, Matthias⋅Clauss, Matthias and Clauss, Matthias
Circulation, vol. 138, (no. Suppl_1 Suppl 1), pp. A17112, 2018-November-6. | Journal Article
 
Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of the transient receptor potential A1 (TRPA1) channel.
The Journal of biological chemistry. | Journal Article
 
Catechol estrogens stimulate insulin secretion in pancreatic β-cells via activation of TRPA1 channel.
Ma, Wenzhen⋅Chen, Xingjuan⋅Cerne, Rok⋅Syed, Samreen K⋅Ficorilli, James⋅Cabrera, Over⋅Obukhov, Alexander G and Efanov, Alexander M
The Journal of biological chemistry, December 26, 2018. | Journal Article
 
Loss of Angiotensin‐Converting Enzyme 2 Exacerbates Diabetic Retinopathy by Promoting Bone Marrow Dysfunction
Duan, Yaqian⋅Duan, Yaqian⋅Beli, Eleni⋅Beli, Eleni⋅Li Calzi, Sergio⋅Li Calzi, Sergio⋅Quigley, Judith L⋅Quigley, Judith L⋅Miller, Rehae C⋅Miller, Rehae C⋅Moldovan, Leni⋅Moldovan, Leni⋅Feng, Dongni⋅Feng, Dongni⋅Salazar, Tatiana E⋅Salazar, Tatiana E⋅Hazra, Sugata⋅Hazra, Sugata⋅Al‐Sabah, Jude⋅Al‐Sabah, Jude⋅Chalam, Kakarla V⋅Chalam, Kakarla V⋅Phuong Trinh, Thao Le⋅Phuong Trinh, Thao Le⋅Meroueh, Marya⋅Meroueh, Marya⋅Markel, Troy A⋅Markel, Troy A⋅Murray, Matthew C⋅Murray, Matthew C⋅Vyas, Ruchi J⋅Vyas, Ruchi J⋅Boulton, Michael E⋅Boulton, Michael E⋅Parsons‐Wingerter, Patricia⋅Parsons‐Wingerter, Patricia⋅Oudit, Gavin Y⋅Oudit, Gavin Y⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅Grant, Maria B and Grant, Maria B
STEM CELLS, vol. 36, (no. 9), pp. 1440, September 2018. | Journal Article
 
Phenylephrine, a common cold remedy active ingredient, suppresses uterine contractions through cAMP signalling
Chen, Xingjuan⋅Meroueh, Marya⋅Mazur, Gabriela⋅Rouse, Evan⋅Stamatkin, Christopher and Obukhov, Alexander
Scientific Reports (Nature Publisher Group), vol. 8, pp. 1-14, Aug 2018. | Journal Article
 
R125H, W240S, C386R, and V507I SLC4A11 mutations associated with corneal endothelial dystrophy affect the transporter function but not trafficking in PS120 cells.
Li, Shimin⋅Li, Shimin⋅Li, Shimin⋅Hundal, Karmjot Singh⋅Hundal, Karmjot Singh⋅Hundal, Karmjot Singh⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Choi, Moonjung⋅Choi, Moonjung⋅Choi, Moonjung⋅Ogando, Diego G⋅Ogando, Diego G⋅Ogando, Diego G⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅Bonanno, Joseph A⋅Bonanno, Joseph A and Bonanno, Joseph A
Experimental eye research, December 14, 2018. | Journal Article
 
Small-molecule Ca V α 1 ⋅Ca V β antagonist suppresses neuronal voltage-gated calcium-channel trafficking
Chen, Xingjuan⋅Chen, Xingjuan⋅Liu, Degang⋅Liu, Degang⋅Zhou, Donghui⋅Zhou, Donghui⋅Si, Yubing⋅Si, Yubing⋅Xu, David⋅Xu, David⋅Stamatkin, Christopher W⋅Stamatkin, Christopher W⋅Ghozayel, Mona K⋅Ghozayel, Mona K⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅White, Fletcher A⋅White, Fletcher A⋅Meroueh, Samy O and Meroueh, Samy O
Proceedings of the National Academy of Sciences of the United States of America, vol. 115, (no. 45), pp. E10566, 2018-11-06. | Journal Article
 
Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking.
Chen, Xingjuan⋅Chen, Xingjuan⋅Liu, Degang⋅Liu, Degang⋅Zhou, Donghui⋅Zhou, Donghui⋅Si, Yubing⋅Si, Yubing⋅Xu, David⋅Xu, David⋅Stamatkin, Christopher W⋅Stamatkin, Christopher W⋅Ghozayel, Mona K⋅Ghozayel, Mona K⋅Ripsch, Matthew S⋅Ripsch, Matthew S⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅White, Fletcher A⋅White, Fletcher A⋅Meroueh, Samy O and Meroueh, Samy O
Proceedings of the National Academy of Sciences of the United States of America, October 24, 2018. | Journal Article
2017
Endothelial Cell–Specific Deletion of P2Y2 Receptor Promotes Plaque Stability in Atherosclerosis-Susceptible ApoE-Null Mice
Chen, Xingjuan⋅Qian, Shaomin⋅Hoggatt, April⋅Tang, Hongying⋅Hacker, Timothy⋅Obukhov, Alexander⋅Herring, Paul and Seye, Cheikh
Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 37, (no. 1), pp. 83, 2017-January. | Journal Article
 
Long-term spironolactone treatment reduces coronary TRPC expression, vasoconstriction, and atherosclerosis in metabolic syndrome pigs
Li, Wennan⋅Li, Wennan⋅Li, Wennan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Riley, Ashley⋅Riley, Ashley⋅Riley, Ashley⋅Hiett, S⋅Hiett, S⋅Hiett, S⋅Temm, Constance⋅Temm, Constance⋅Temm, Constance⋅Beli, Eleni⋅Beli, Eleni⋅Beli, Eleni⋅Long, Xin⋅Long, Xin⋅Long, Xin⋅Chakraborty, Saikat⋅Chakraborty, Saikat⋅Chakraborty, Saikat⋅Alloosh, Mouhamad⋅Alloosh, Mouhamad⋅Alloosh, Mouhamad⋅White, Fletcher⋅White, Fletcher⋅White, Fletcher⋅Grant, Maria⋅Grant, Maria⋅Grant, Maria⋅Sturek, Michael⋅Sturek, Michael⋅Sturek, Michael⋅Obukhov, Alexander⋅Obukhov, Alexander and Obukhov, Alexander
Basic Research in Cardiology, vol. 112, (no. 5), pp. 20, 20170900. | Journal Article
 
Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+Potentiation, and Ca2+Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel
Chen, Xingjuan⋅Li, Wennan⋅Riley, Ashley M⋅Soliman, Mario⋅Chakraborty, Saikat⋅Stamatkin, Christopher W and Obukhov, Alexander G
The Journal of biological chemistry, vol. 292, (no. 3), pp. 911, 2017-01-20. | Journal Article
2016
Abstract 19266: Renin-Angiotensin Axis in Hematopoietic Stem/Progenitor Cells Predicts Vascular Dysfunction and Diabetic Retinopathy
Duan, Yaqian⋅Duan, Yaqian⋅Miller, Rehae⋅Miller, Rehae⋅Moldovan, Leni⋅Moldovan, Leni⋅Beli, Eleni⋅Beli, Eleni⋅Salazar, Tatiana⋅Salazar, Tatiana⋅Li Calzi, Sergio⋅Li Calzi, Sergio⋅Hazra, Sugata⋅Hazra, Sugata⋅Al-Sabah, Jude⋅Al-Sabah, Jude⋅Meroueh, Marya⋅Meroueh, Marya⋅Chalam, Kakarla⋅Chalam, Kakarla⋅Raghunandan, Sneha⋅Raghunandan, Sneha⋅Vyas, Ruchi⋅Vyas, Ruchi⋅Parsons-Wingerter, Patricia⋅Parsons-Wingerter, Patricia⋅Oudit, Gavin⋅Oudit, Gavin⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Grant, Maria and Grant, Maria
Circulation, vol. 134, (no. Suppl_1 Suppl 1), pp. A19266, 2016-November-11. | Journal Article
 
Novel Roles for Kv7 Channels in Shaping Histamine-Induced Contractions and Bradykinin-Dependent Relaxations in Pig Coronary Arteries
Chen, Xingjuan⋅Li, Wennan⋅Hiett, S Christopher and Obukhov, Alexander G
PloS one, vol. 11, (no. 2), pp. e0148569, 2016-00-00. | Journal Article
 
Transient receptor potential channels in metabolic syndrome-induced coronary artery disease
Dineen, S.L.⋅Neeb, Z.P.⋅Obukhov, A.G. and Sturek, M.
2016
2015
Human SLC4A11 Is a Novel NH3/H+Co-transporter
Zhang, Wenlin⋅Ogando, Diego G⋅Bonanno, Joseph A and Obukhov, Alexander G
The Journal of biological chemistry, vol. 290, (no. 27), pp. 16905, 2015-Jul-03. | Journal Article
2014
Furanocoumarins are a novel class of modulators for the transient receptor potential vanilloid type 1 (TRPV1) channel.
Chen, Xingjuan⋅Chen, Xingjuan⋅Sun, Weiyang⋅Sun, Weiyang⋅Gianaris, Nicholas G⋅Gianaris, Nicholas G⋅Riley, Ashley M⋅Riley, Ashley M⋅Cummins, Theodore R⋅Cummins, Theodore R⋅Fehrenbacher, Jill C⋅Fehrenbacher, Jill C⋅Obukhov, Alexander G and Obukhov, Alexander G
The Journal of biological chemistry, vol. 289, (no. 14), pp. 9600-9610, April 4, 2014. | Journal Article
 
Mechanisms underlying capsaicin effects in canine coronary artery: implications for coronary spasm.
Hiett, S Christopher⋅Owen, Meredith K⋅Li, Wennan⋅Chen, Xingjuan⋅Riley, Ashley⋅Noblet, Jillian⋅Flores, Sarah⋅Sturek, Michael⋅Tune, Johnathan D and Obukhov, Alexander G
Cardiovascular research, vol. 103, (no. 4), pp. 607-618, September 1, 2014. | Journal Article
 
PKC-dependent Phosphorylation of the H1 Histamine Receptor Modulates TRPC6 Activity
Chen, Xingjuan⋅Chen, Xingjuan⋅Egly, Christian⋅Egly, Christian⋅Riley, Ashley M⋅Riley, Ashley M⋅Li, Wennan⋅Li, Wennan⋅Tewson, Paul⋅Tewson, Paul⋅Hughes, Thom⋅Hughes, Thomas E⋅Quinn, Anne Marie⋅Quinn, Anne M⋅Obukhov, Alexander G and Obukhov, Alexander G
Cells, vol. 3, (no. 2), pp. 257, 2014-Apr-04. | Journal Article
 
Primary cilia signaling mediates intraocular pressure sensation.
Luo, Na⋅Luo, Na⋅Conwell, Michael D⋅Conwell, Michael D⋅Chen, Xingjuan⋅Chen, Xingjuan⋅Kettenhofen, Christine Insinna⋅Kettenhofen, Christine I⋅Westlake, Christopher J⋅Westlake, Christopher J⋅Cantor, Louis B⋅Cantor, Louis B⋅Wells, Clark D⋅Wells, Clark D⋅Weinreb, Robert N⋅Weinreb, Robert N⋅Corson, Timothy W⋅Corson, Timothy W⋅Spandau, Dan F⋅Spandau, Dan F⋅Joos, Karen M⋅Joos, Karen M⋅Iomini, Carlo⋅Iomini, Carlo⋅Obukhov, Alexander G⋅Obukhov, Alexander G⋅Sun, Yang and Sun, Yang
Proceedings of the National Academy of Sciences of the United States of America, vol. 111, (no. 35), pp. 12871-6, 2014/Sep/2. | Journal Article
2013
Contribution of electromechanical coupling between Kv and Ca v1.2 channels to coronary dysfunction in obesity.
Berwick, Zachary⋅Berwick, Zachary⋅Berwick, Z.C.⋅Berwick, Zachary C⋅Dick, Gregory⋅Dick, Gregory⋅Dick, G.M.⋅Dick, Gregory M⋅O'Leary, Heather A⋅O’Leary, H.A.⋅O’Leary, Heather⋅O’Leary, Heather⋅Bender, Shawn⋅Bender, Shawn B⋅Bender, Shawn⋅Bender, S.B.⋅Goodwill, Adam G⋅Goodwill, Adam⋅Goodwill, Adam⋅Goodwill, A.G.⋅Moberly, S.P.⋅Moberly, Steven⋅Moberly, Steven⋅Moberly, Steven P⋅Owen, Meredith⋅Owen, Meredith K⋅Owen, M.K.⋅Owen, Meredith⋅Miller, Steven⋅Miller, Steven⋅Miller, S.J.⋅Miller, Steven J⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Obukhov, A.G.⋅Obukhov, Alexander G⋅Tune, J.D.⋅Tune, Johnathan⋅Tune, Johnathan and Tune, Johnathan D
Basic research in cardiology, vol. 108, (no. 5), pp. 370, 2013/Sep. | Journal Article
2012
Altered calcium signaling in colonic smooth muscle of type 1 diabetic mice
Touw, Ketrija⋅Touw, Ketrija⋅Chakraborty, Saikat⋅Chakraborty, Saikat⋅Zhang, Wenwu⋅Zhang, Wenwu⋅Obukhov, Alexander⋅Obukhov, Alexander⋅Tune, Johnathan D⋅Tune, Johnathan⋅Gunst, Susan J⋅Gunst, Susan⋅Herring, B. P and Herring, B.
American Journal of Physiology, vol. 302, (no. 1), Jan 2012. | Journal Article
 
Constitutive activity of TRPML2 and TRPML3 channels versus activation by low extracellular sodium and small molecules.
Grimm, Christian⋅Jörs, Simone⋅Guo, Zhaohua⋅Obukhov, Alexander G and Heller, Stefan
The Journal of biological chemistry, vol. 287, (no. 27), pp. 22701-8, 2012/Jun/29. | Journal Article