108 Publications (Page 3 of 5)
2010
Small molecule activators of TRPML3.
Grimm, ChristianGrimm, C.Jörs, SimoneJörs, S.Saldanha, S ASaldanha, S.A.Obukhov, Alexander GObukhov, A.G.Pan, B.Pan, BifengOshima, K.Oshima, KazuoCuajungco, M.P.Cuajungco, Math PChase, PeterChase, P.Hodder, PeterHodder, P.Heller, S. and Heller, Stefan
Chemistry & biology, vol. 17, (no. 2), pp. 135-48, 2010/Feb/26. | Journal Article
2009
Canonical transient receptor potential channels expression is elevated in a porcine model of metabolic syndrome.
Hu, GuoqingOboukhova, Elena AKumar, SanjaySturek, Michael and Obukhov, Alexander G
Molecular endocrinology (Baltimore, Md.), vol. 23, (no. 5), pp. 689-99, 2009/May. | Journal Article
 
CFTR regulation of intracellular pH and ceramides is required for lung endothelial cell apoptosis.
Noe, JuliePetrusca, DanielaRush, NataliaDeng, PingVanDemark, MaryBerdyshev, EvgenyGu, YuanSmith, PatriciaSchweitzer, Kelly SPilewsky, JosephNatarajan, ViswanathanXu, Zao CObukhov, Alexander G and Petrache, Irina
American journal of respiratory cell and molecular biology, vol. 41, (no. 3), pp. 314-23, 2009/Sep. | Journal Article
2008
TRPC5 channels undergo changes in gating properties during the activation-deactivation cycle.
Obukhov, Alexander G and Nowycky, Martha C
Journal of cellular physiology, vol. 216, (no. 1), pp. 162-71, 2008/Jul. | Journal Article
2007
Induction of calcium influx through TRPC5 channels by cross-linking of GM1 ganglioside associated with alpha5beta1 integrin initiates neurite outgrowth.
Wu, GushengLu, Zi-HuaObukhov, Alexander GNowycky, Martha C and Ledeen, Robert W
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 27, (no. 28), pp. 7447-58, 2007/Jul/11. | Journal Article
 
Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with alpha 5 beta 1 Integrin Initiates Neurite Outgrowth
Wu, GushengLu, Zi-HuaObukhov, AlexanderNowycky, Martha C and Ledeen, Robert W
Journal of Neuroscience, vol. 27, (no. 28), pp. 7447-7458, 2007. | Journal Article
 
Induction of Calcium Influx through TRPC5 Channels by Cross-Linking of GM1 Ganglioside Associated with α5β1 Integrin Initiates Neurite Outgrowth
Wu, GushengWu, GushengLu, Zi-HuaLu, Zi-HuaObukhov, AlexanderObukhov, Alexander GNowycky, Martha CNowycky, MarthaLedeen, Robert W and Ledeen, Robert
The Journal of Neuroscience, vol. 27, (no. 28), pp. 7458, 2007-07-11. | Journal Article
 
In vivo identification and manipulation of the Ca2+ selectivity filter in the Drosophila transient receptor potential channel.
Liu, Che HWang, TaoPostma, MartenObukhov, Alexander GMontell, Craig and Hardie, Roger C
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 27, (no. 3), pp. 604-15, 2007/Jan/17. | Journal Article
 
In Vivo Identification and Manipulation of the Ca2+ Selectivity Filter in the Drosophila Transient Receptor Potential Channel
Liu, CheWang, TaoPostma, MartenObukhov, AlexanderMontell, Craig and Hardie, Roger
Journal of Neuroscience, vol. 27, (no. 3), pp. 615, 20070117. | Journal Article
 
In Vivo Identification and Manipulation of the Ca super(2+) Selectivity Filter in the Drosophila Transient Receptor Potential Channel
Liu, Che HWang, TaoPostma, MartenObukhov, AlexanderMontell, Craig and Hardie, Roger C
Journal of Neuroscience, vol. 27, (no. 3), pp. 604-615, 2007. | Journal Article
 
New insights into the function and regulation of vitamin D target proteins.
Christakos, SylviaDhawan, PuneetPeng, XiaorongObukhov, Alexander GNowycky, Martha CBenn, Bryan SZhong, YanLiu, Yan and Shen, Qi
The Journal of steroid biochemistry and molecular biology, vol. 103, (no. 3-5), pp. 405-10, 2007/Mar. | Journal Article
 
Voltage-gated K.sup.+ channels expressed in canine coronary artery
Dincer, U.Dincer, U.Dick, GregoryDick, GregoryObukhov, AlexanderObukhov, AlexanderJr., Henry R. BeschJr., Henry R. BeschSturek, MichaelSturek, MichaelTune, Johnathan and Tune, Johnathan
Journal of Molecular and Cellular Cardiology, vol. 42, (no. 6), pp. S16, 20070601. | Journal Article
2006
Calbindin-D28k decreases L-type calcium channel activity and modulates intracellular calcium homeostasis in response to K+ depolarization in a rat beta cell line RINr1046-38.
Lee, DavidObukhov, Alexander GShen, QiLiu, YanDhawan, PuneetNowycky, Martha C and Christakos, Sylvia
Cell calcium, vol. 39, (no. 6), pp. 475-485, 2006/Jun. | Journal Article
 
Calbindin-D sub(28k) decreases L-type calcium channel activity and modulates intracellular calcium homeostasis in response to K super(+) depolarization in a rat beta cell line RINr1046-38
Lee, DavidObukhov, AlexanderShen, QiLiu, YanDhawan, PuneetNowycky, Martha C and Christakos, Sylvia
Cell Calcium, vol. 39, (no. 6), pp. 475-485, 2006. | Journal Article
2005
A cytosolic residue mediates Mg2+ block and regulates inward current amplitude of a transient receptor potential channel.
Obukhov, Alexander G and Nowycky, Martha C
The Journal of neuroscience : the official journal of the Society for Neuroscience. , vol. 25, (no. 5), pp. 1234-9, 2005/Feb/2. | Journal Article
 
A Cytosolic Residue Mediates Mg2+ Block and Regulates Inward Current Amplitude of a Transient Receptor Potential Channel
Obukhov, Alexander and Nowycky, Martha
Journal of Neuroscience, vol. 25, (no. 5), pp. 1239, 20050202. | Journal Article
 
Protein kinase C? modulates depolarizaton-evoked changes of intracellular Ca2+ concentration in a rat pheochromocytoma cell line
Fontainhas, A.M.Obukhov, A.G. and Nowycky, M.C.
Neuroscience, vol. 133, pp. 393-403. | Journal Article
2004
TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50).
Obukhov, Alexander G and Nowycky, Martha C
Journal of cellular physiology, vol. 201, (no. 2), pp. 227-35, 2004/Nov. | Journal Article
 
TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin‐binding phosphoprotein‐50 (EBP50)
Obukhov, Alexander G and Nowycky, Martha C
Journal of Cellular Physiology, vol. 201, (no. 2), pp. 235, November 2004. | Journal Article
 
TRPC5 activation kinetics are modulated by the scaffolding protein ezrin/radixin/moesin-binding phosphoprotein-50 (EBP50).(Author Abstract)
Nowycky, Martha and Obukhov, Alexander
Journal of General Physiology, vol. 124, (no. 1), pp. 25, 20040701. | Journal Article
2002
TRPC4 can be activated by G-protein-coupled receptors and provides sufficient Ca(2+) to trigger exocytosis in neuroendocrine cells.
Obukhov, Alexander G and Nowycky, Martha C
The Journal of biological chemistry, vol. 277, (no. 18), pp. 16172-8, 2002/May/3. | Journal Article
 
TRPC4 Can Be Activated by G-protein-coupled Receptors and Provides Sufficient Ca2+ to Trigger Exocytosis in Neuroendocrine Cells
Obukhov, Alexander and Nowycky, Martha
Journal of Biological Chemistry, vol. 277, (no. 18), pp. 16178, 20020503. | Journal Article
2000
Receptor-mediated regulation of the nonselective cation channels TRPC4 and TRPC5.
Schaefer, MPlant, T DObukhov, Alexander GHofmann, TGudermann, T and Schultz, G
The Journal of biological chemistry, vol. 275, (no. 23), pp. 17517-26, 2000/Jun/9. | Journal Article
1999
Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol
Hofmann, T.Obukhov, AlexanderSchaefer, M.Harteneck, C.Gudermann, T. and Schultz, G.
Nature, vol. 397, (no. 6716), pp. 259-263, 1999. | Journal Article
1998
Regulation of heterologously expressed transient receptor potential- like channels by calcium ions
Obukhov, A.G.Schultz, G. and Lückhoff, A.
Neuroscience, vol. 85, pp. 487-495. | Journal Article