19 Publications
Soypeptide lunasin in cytokine immunotherapy for lymphoma.
Chang, Hua ChenChang, Hua-ChenChang, Hua-ChenLewis, DavidLewis, DavidLewis, DavidTung, Chun-YuTung, Chun-YuTung, Chun-YuHan, LingHan, LingHan, LingHenriquez, Sarah MHenriquez, SarahHenriquez, SarahVoiles, LarryVoiles, LarryVoiles, LarryLupov, Ivan PLupov, IvanLupov, IvanPelloso, DavidPelloso, DavidPelloso, DavidSinn, AnthonySinn, Anthony LSinn, AnthonyPollok, KarenPollok, Karen EPollok, Karende Lumen, Ben Ode Lumen, Bende Lumen, BenLi, FangLi, FangLi, FangBlum, JaniceBlum, Janice SBlum, JaniceSrivastava, ShivaniSrivastava, ShivaniSrivastava, ShivaniRobertson, MichaelRobertson, Michael J and Robertson, Michael
Cancer immunology, immunotherapy : CII, vol. 63, (no. 3), pp. 283-95, 2014/Mar. | Journal Article
The transcription factor PU.1 regulates γδ T cell homeostasis.
Jabeen, RukhsanaChang, Hua ChenGoswami, RitobrataNutt, Stephen L and Kaplan, Mark H
PloS one, vol. 6, (no. 7), pp. e22189, 2011. | Journal Article
The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation.
Chang, Hua-ChenChang, Hua ChenSehra, SaritaSehra, SaritaGoswami, RitobrataGoswami, RitobrataYao, WeiguoYao, WeiguoYu, QingYu, QingStritesky, Gretta LStritesky, Gretta LJabeen, RukhsanaJabeen, RukhsanaMcKinley, CarlMcKinley, CarlAhyi, Ayele-NatiAhyi, Ayele-NatiHan, LingHan, LingNguyen, Evelyn TNguyen, Evelyn TRobertson, Michael JRobertson, Michael JPerumal, Narayanan BPerumal, Narayanan BTepper, Robert STepper, Robert SNutt, Stephen LNutt, Stephen LKaplan, Mark H and Kaplan, Mark H
Nature immunology, vol. 11, (no. 6), pp. 527-34, 2010/Jun. | Journal Article
IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.
Ahyi, Ayele-Nati NChang, Hua ChenDent, Alexander LNutt, Stephen L and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 183, (no. 3), pp. 1598-606, 2009/Aug/1. | Journal Article
Impaired development of human Th1 cells in patients with deficient expression of STAT4.
Chang, Hua ChenHan, LingGoswami, RitobrataNguyen, Evelyn TPelloso, DavidRobertson, Michael J and Kaplan, Mark H
Blood, vol. 113, (no. 23), pp. 5887-90, 2009/Jun/4. | Journal Article
PU.1 regulates TCR expression by modulating GATA-3 activity.
Chang, Hua ChenHan, LingJabeen, RukhsanaCarotta, SebastianNutt, Stephen L and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 183, (no. 8), pp. 4887-94, 2009/Oct/15. | Journal Article
Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells
O'Malley, John TSehra, SaritaThieu, Vivian TYu, QingChang, Hua ChenStritesky, Gretta LNguyen, Evelyn TMathur, Anubhav NLevy, David E and Kaplan, Mark H
Immunology, vol. 127, (no. 4), pp. 587-595, 2009. | Journal Article
Signal transducer and activator of transcription 4 is required for the transcription factor T-bet to promote T helper 1 cell-fate determination.
Thieu, Vivian TThieu, Vivian TYu, QingYu, QingChang, Hua-ChenChang, Hua ChenYeh, NormanYeh, NormanNguyen, Evelyn TNguyen, Evelyn TSehra, SaritaSehra, SaritaKaplan, Mark H and Kaplan, Mark H
Immunity, vol. 29, (no. 5), pp. 679-90, 2008/Nov/14. | Journal Article
STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.
O'Malley, John TEri, Rajaraman DStritesky, Gretta LMathur, Anubhav NChang, Hua ChenHogen Esch, HarmHogenesch, HarmSrinivasan, Mythily and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 7), pp. 5062-70, 2008/Oct/1. | Journal Article
Transcription factor-dependent chromatin remodeling of Il18r1 during Th1 and Th2 differentiation.
Yu, QingChang, Hua ChenAhyi, Ayele-Nati N and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 5), pp. 3346-52, 2008/Sep/1. | Journal Article
Vaccinia virus blocks Stat1-dependent and Stat1-independent gene expression induced by type I and type II interferons.
Mann, Brandon AHuang, Julia HLi, PingChang, Hua ChenSlee, Roger BO'Sullivan, AudreyAnita, MathurYeh, NormanKlemsz, Michael JBrutkiewicz, Randy RBlum, Janice S and Kaplan, Mark H
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, vol. 28, (no. 6), pp. 367-80, 2008/Jun. | Journal Article
Rap1a Null Mice Have Altered Myeloid Cell Functions Suggesting Distinct Roles for the Closely Related Rap1a and 1b Proteins
Li, YuLi, YuLi, YuYan, JingliangYan, JingliangYan, JingliangDe, PradipDe, PradipDe, PradipChang, Hua-ChenChang, Hua ChenChang, Hua-ChenYamauchi, AkiraYamauchi, AkiraYamauchi, AkiraChristopherson, KentChristopherson, Kent WChristopherson, KentParanavitana, NivankaParanavitana, Nivanka CParanavitana, NivankaPeng, XiaodongPeng, XiaodongPeng, XiaodongKim, ChaekyunKim, ChaekyunKim, ChaekyunMunugulavadla, VeerendraMunugulavadla, VeerendraMunugulavadla, VeerendraKapur, ReubenKapur, ReubenKapur, ReubenChen, HanyingChen, HanyingChen, HanyingShou, WeinianShou, WeinianShou, WeinianStone, JamesStone, James CStone, JamesKaplan, Mark HKaplan, MarkKaplan, MarkDinauer, MaryDinauer, Mary CDinauer, MaryDurden, DonaldDurden, DonaldDurden, Donald LQuilliam, LawrenceQuilliam, Lawrence and Quilliam, Lawrence A
Journal of Immunology, vol. 179, (no. 12), pp. 8322-8331, 2007. | Journal Article
Stat3 and Stat4 direct development of IL-17-secreting Th cells.
Mathur, Anubhav NChang, Hua ChenZisoulis, Dimitrios GStritesky, Gretta LYu, QingO'Malley, John TKapur, ReubenLevy, David EKansas, Geoffrey S and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 178, (no. 8), pp. 4901-7, 2007/Apr/15. | Journal Article
T-bet is a critical determinant in the instability of the IL-17-secreting T-helper phenotype.
Mathur, Anubhav NChang, Hua ChenZisoulis, Dimitrios GKapur, ReubenBelladonna, Maria LKansas, Geoffrey S and Kaplan, Mark H
Blood, vol. 108, (no. 5), pp. 1595-601, 2006/Sep/1. | Journal Article
PU.1 expression delineates heterogeneity in primary Th2 cells.
Chang, Hua ChenZhang, ShangmingThieu, Vivian TSlee, Roger BBruns, Heather ALaribee, R NKlemsz, Michael J and Kaplan, Mark H
Immunity, vol. 22, (no. 6), pp. 693-703, 2005/Jun. | Journal Article
STAT4 is required for interleukin-12-induced chromatin remodeling of the CD25 locus.
O'Sullivan, AudreyChang, Hua ChenYu, Qing and Kaplan, Mark H
The Journal of biological chemistry, vol. 279, (no. 8), pp. 7339-45, 2004/Feb/20. | Journal Article
Distinct requirements for Stat4 and Stat6 in hematopoietic progenitor cell responses to growth factors and chemokines.
Kaplan, Mark HChang, Hua ChenCooper, ScottLee, Younghee and Broxmeyer, Hal E
Journal of hematotherapy & stem cell research. , vol. 12, (no. 4), pp. 401-8, 2003/Aug. | Journal Article
STAT4 requires the N-terminal domain for efficient phosphorylation.
Chang, Hua ChenZhang, ShangmingOldham, IndiaNaeger, LisaHoey, Timothy and Kaplan, Mark H
The Journal of biological chemistry, vol. 278, (no. 34), pp. 32471-7, 2003/Aug/22. | Journal Article
Neonatal tolerance in the absence of Stat4- and Stat6- dependent Th cell differentiation.
Chang, Hua ChenZhang, Shangming and Kaplan, Mark H
Journal of immunology (Baltimore, Md. : 1950), vol. 169, (no. 8), pp. 4124-8, 2002/Oct/15. | Journal Article