189 Publications (Page 6 of 8)
2011
The emerging role of electronic medical records in pharmacogenomics.
Wilke, Russell⋅Xu, H⋅Denny, J C⋅Roden, D M⋅Krauss, R M⋅Mc Carty, C A⋅Davis, R L⋅Skaar, T⋅Lamba, Jatinder K and Savova, G
Clinical pharmacology and therapeutics, vol. 89, (no. 3), pp. 379-86, 2011/Mar. | Journal Article
2010
Abstract 3604: Significant effect of polymorphisms in CYP2D6 and DT-1 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients
Zembutsu, Hitoshi⋅Zembutsu, Hitoshi⋅Kiyotani, Kazuma⋅Kiyotani, Kazuma⋅Mushiroda, Taisei⋅Mushiroda, Taisei⋅Imamura, Chiyo K⋅Imamura, Chiyo K⋅Hosono, Naoya⋅Hosono, Naoya⋅Kubo, Michiaki⋅Kubo, Michiaki⋅Tanigawara, Yusuke⋅Tanigawara, Yusuke⋅Flockhart, David A⋅Flockhart, David A⋅Skaar, Todd C⋅Skaar, Todd C⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Aki, Fuminori⋅Aki, Fuminori⋅Hirata, Koichi⋅Hirata, Koichi⋅Takatsuka, Yuichi⋅Takatsuka, Yuichi⋅Okazaki, Minoru⋅Okazaki, Minoru⋅Ohsumi, Shozo⋅Ohsumi, Shozo⋅Yamakawa, Takashi⋅Yamakawa, Takashi⋅Sasa, Mitsunori⋅Sasa, Mitsunori⋅Nakamura, Yusuke and Nakamura, Yusuke
Cancer Research, vol. 70, (no. 8 Supplement), pp. 3604, 2010-04-15. | Journal Article
 
Composite functional genetic and comedication CYP2D6 activity score in predicting tamoxifen drug exposure among breast cancer patients.
Borges, Silvana⋅Desta, Zeruesenay⋅Jin, Yan⋅Faouzi, Azzouz⋅Robarge, Jason D⋅Philips, Sanosh⋅Nguyen, Anne⋅Stearns, Vered⋅Hayes, Daniel F⋅Rae, James⋅Skaar, Todd C⋅Flockhart, David A and Li, Lang
Journal of clinical pharmacology, vol. 50, (no. 4), pp. 450-8, 2010/Apr. | Journal Article
 
Differential quantification of CYP2D6 gene copy number by four different quantitative real-time PCR assays.
Ramamoorthy, Anuradha⋅Flockhart, David A⋅Hosono, Naoya⋅Kubo, Michiaki⋅Nakamura, Yusuke and Skaar, Todd C
Pharmacogenetics and genomics, vol. 20, (no. 7), pp. 451-4, 2010/Jul. | Journal Article
 
Estrogen receptor genotypes, menopausal status, and the effects of tamoxifen on lipid levels: revised and updated results.
Hayes, Daniel F⋅Skaar, T C⋅Rae, James⋅Henry, Norah L⋅Nguyen, A T⋅Stearns, V⋅Li, L⋅Philips, S⋅Desta, Z and Flockhart, D A
Clinical pharmacology and therapeutics, vol. 88, (no. 5), pp. 626-9, 2010/Nov. | Journal Article
 
Impact of proton pump inhibitors on the effectiveness of clopidogrel after coronary stent placement: the clopidogrel Medco outcomes study.
Kreutz, Rolf P⋅Kreutz, Rolf P⋅Stanek, Eric J⋅Stanek, Eric J⋅Aubert, Ronald⋅Aubert, Ronald⋅Yao, Jianying⋅Yao, Jianying⋅Breall, Jeffrey A⋅Breall, Jeffrey A⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Skaar, Todd C⋅Skaar, Todd C⋅Teagarden, J R⋅Teagarden, J. Russell⋅Frueh, Felix W⋅Frueh, Felix W⋅Epstein, Robert S⋅Epstein, Robert S⋅Flockhart, David A and Flockhart, David A
Pharmacotherapy, vol. 30, (no. 8), pp. 787-96, 2010/Aug. | Journal Article
 
Lack of association between oestrogen receptor polymorphisms and change in bone mineral density with tamoxifen therapy.
Henry, Norah L⋅Nguyen, A⋅Azzouz, F⋅Li, L⋅Robarge, J⋅Philips, S⋅Cao, D⋅Skaar, T C⋅Rae, James⋅Storniolo, A M⋅Flockhart, D A⋅Hayes, Daniel F and Stearns, V
British journal of cancer, vol. 102, (no. 2), pp. 294-300, 2010/Jan/19. | Journal Article
 
Resequencing of the vascular endothelial growth factor promoter reveals haplotype structure and functional diversity.
Radovich, Milan⋅Hancock, Bradley A⋅Kassem, Nawal⋅Mi, Deming⋅Skaar, Todd C and Schneider, Bryan P
Angiogenesis, vol. 13, (no. 3), pp. 211-8, 2010/Sep. | Journal Article
 
Significant effect of polymorphisms in CYP2D6 and ABCC2 on clinical outcomes of adjuvant tamoxifen therapy for breast cancer patients.
Kiyotani, Kazuma⋅Kiyotani, Kazuma⋅Mushiroda, Taisei⋅Mushiroda, Taisei⋅Imamura, Chiyo⋅Imamura, Chiyo K⋅Hosono, Naoya⋅Hosono, Naoya⋅Tsunoda, Tatsuhiko⋅Tsunoda, Tatsuhiko⋅Kubo, Michiaki⋅Kubo, Michiaki⋅Tanigawara, Yusuke⋅Tanigawara, Yusuke⋅Flockhart, David A⋅Flockhart, David⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Skaar, Todd C⋅Skaar, Todd⋅Aki, Fuminori⋅Aki, Fuminori⋅Hirata, Koichi⋅Hirata, Koichi⋅Takatsuka, Yuichi⋅Takatsuka, Yuichi⋅Okazaki, Minoru⋅Okazaki, Minoru⋅Ohsumi, Shozo⋅Ohsumi, Shozo⋅Yamakawa, Takashi⋅Yamakawa, Takashi⋅Sasa, Mitsunori⋅Sasa, Mitsunori⋅Nakamura, Yusuke⋅Nakamura, Yusuke⋅Zembutsu, Hitoshi and Zembutsu, Hitoshi
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 28, (no. 8), pp. 1287-93, 2010/Mar/10. | Journal Article
2009
Antiestrogen pathway (aromatase inhibitor).
Desta, Zeruesenay⋅Nguyen, Anne⋅Flockhart, David A⋅Skaar, Todd C⋅Fletcher, Rebecca⋅Weinshilboum, Richard M⋅Berlin, Dorit S⋅Klein, Teri E and Altman, Russ B
Pharmacogenetics and genomics, vol. 19, (no. 7), pp. 554-5, 2009/Jul. | Journal Article
 
A phase II study of pemetrexed as second-line chemotherapy for the treatment of metastatic castrate-resistant prostate cancer (CRPC); Hoosier Oncology Group GU03-67.
Hahn, Noah⋅Zon, R T⋅Yu, M⋅Ademuyiwa, Foluso O⋅Jones, T⋅Dugan, W⋅Whalen, C⋅Shanmugam, R⋅Skaar, T and Sweeney, Christopher J
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO, vol. 20, (no. 12), pp. 1971-6, 2009/Dec. | Journal Article
 
Association between CYP2D6 genotype and tamoxifen-induced hot flashes in a prospective cohort.
Henry, N Lynn⋅Henry, Norah L⋅Rae, James⋅Rae, James M⋅Li, Lang⋅Li, Lang⋅Azzouz, Faouzi⋅Azzouz, Faouzi⋅Skaar, Todd C⋅Skaar, Todd C⋅Desta, Zereunesay⋅Desta, Zereunesay⋅Sikora, Matthew J⋅Sikora, Matthew J⋅Philips, Santosh⋅Philips, Santosh⋅Nguyen, Anne T⋅Nguyen, Anne T⋅Storniolo, Anna Maria⋅Storniolo, Anna M⋅Hayes, Daniel F⋅Hayes, Daniel F⋅Flockhart, David A⋅Flockhart, David A⋅Stearns, Vered and Stearns, Vered
Breast cancer research and treatment, vol. 117, (no. 3), pp. 571-5, 2009/Oct. | Journal Article
 
Clinically available pharmacogenomics tests.
Flockhart, David A⋅Skaar, T⋅Berlin, D S⋅Klein, T E and Nguyen, A T
Clinical pharmacology and therapeutics, vol. 86, (no. 1), pp. 109-13, 2009/Jul. | Journal Article
 
Cytochrome P450 2D6 activity predicts discontinuation of tamoxifen therapy in breast cancer patients.
Rae, James⋅Sikora, M J⋅Henry, Norah L⋅Li, L⋅Kim, S⋅Oesterreich, Steffi⋅Skaar, Todd C⋅Nguyen, A T⋅Desta, Zeruesenay⋅Storniolo, Anna M⋅Flockhart, David A⋅Hayes, Daniel F and Stearns, Vered
The pharmacogenomics journal, vol. 9, (no. 4), pp. 258-64, 2009/Aug. | Journal Article
 
Estrogen receptor genotype is associated with risk of venous thromboembolism during tamoxifen therapy
Onitilo, Adedayo A⋅Mc Carty, Catherine A⋅Wilke, Russell⋅Glurich, Ingrid⋅Engel, Jessica M⋅Flockhart, David A⋅Nguyen, Anne⋅Li, Lang⋅Mi, Deming⋅Skaar, Todd and Jin, Yan
Breast cancer research and treatment., vol. 115, (no. 3), pp. 643-650, 2009. | Journal Article
 
Evaluating the role of serotonin in hot flashes after breast cancer using acute tryptophan depletion.
Carpenter, Janet S⋅Carpenter, Janet⋅Carpenter, Janet⋅Yu, Menggang⋅Yu, Menggang⋅Yu, Menggang⋅Wu, Jingwei⋅Wu, Jingwei⋅Wu, Jingwei⋅Von Ah, Diane⋅Von Ah, Diane⋅Von Ah, Diane⋅Milata, Jennifer⋅Milata, Jennifer⋅Milata, Jennifer⋅Otte, Julie⋅Otte, Julie L⋅Otte, Julie⋅Johns, Shelley⋅Johns, Shelley⋅Johns, Shelley⋅Schneider, Bryan P⋅Schneider, Bryan⋅Schneider, Bryan⋅Storniolo, Anna⋅Storniolo, Anna⋅Storniolo, Anna M⋅Salomon, Ronald⋅Salomon, Ronald⋅Salomon, Ronald⋅Desta, Zeuresenay⋅Desta, Zeuresenay⋅Desta, Zeuresenay⋅Cao, Donghua⋅Cao, Donghua⋅Cao, Donghua⋅Jin, Yan⋅Jin, Yan⋅Jin, Yan⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Skaar, Todd C⋅Skaar, Todd and Skaar, Todd
Menopause (New York, N.Y.), vol. 16, (no. 4), pp. 644-52, 2009 Jul-Aug. | Journal Article
 
Exploratory study evaluating the association of polymorphisms of angiogenesis genes with hot flashes
Schneider, Bryan P⋅Radovich, Milan⋅Flockhart, David A⋅Carpenter, Janet S⋅Li, Lang⋅Robarge, Jason D⋅Storniolo, Anna M⋅Hancock, Bradley A⋅Skaar, Todd and Sledge, George W
Breast Cancer Research and Treatment, vol. 116, (no. 3), pp. 543-9, Aug 2009. | Journal Article
 
Identification of genetic variants in the human indoleamine 2,3-dioxygenase (IDO1) gene, which have altered enzyme activity.
Arefayene, Million⋅Arefayene, Million⋅Philips, Santosh⋅Philips, Santosh⋅Cao, Donghua⋅Cao, Donghua⋅Mamidipalli, Sudharani⋅Mamidipalli, Sudharani⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Flockhart, David A⋅Flockhart, David⋅Wilkes, David⋅Wilkes, David S⋅Skaar, Todd C and Skaar, Todd
Pharmacogenetics and genomics, vol. 19, (no. 6), pp. 464-76, 2009/Jun. | Journal Article
 
Nuclear receptor coregulator SNP discovery and impact on breast cancer risk
Hartmaier, Ryan J⋅Tchatchou, Sandrine⋅Richter, Alexandra S⋅Wang, Jay⋅Mc Guire, Sean E⋅Skaar, Todd C⋅Rae, Jimmy M⋅Hemminki, Kari⋅Sutter, Christian⋅Ditsch, Nina⋅Bugert, Peter⋅Weber, Bernhard H⋅Niederacher, Dieter⋅Arnold, Norbert⋅Varon-Mateeva, Raymonda⋅Wappenschmidt, Barbara⋅Schmutzler, Rita K⋅Meindl, Alfons⋅Bartram, Claus R⋅Burwinkel, Barbara and Oesterreich, Steffi
BMC Cancer, vol. 9, pp. 438-438, 2009. | Journal Article
 
Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition.
Mukherjee, Pinku⋅Basu, Gargi D⋅Tinder, Teresa L⋅Subramani, Durai B⋅Bradley, Judy M⋅Arefayene, Million⋅Skaar, Todd C and De Petris, Giovanni
Journal of immunology (Baltimore, Md. : 1950), vol. 182, (no. 1), pp. 216-24, 2009/Jan/1. | Journal Article
2008
A mixture model approach in gene-gene and gene-environmental interactions for binary phenotypes.
Li, Lang⋅Yu, Menggang⋅Jason, Robarge D⋅Shen, Changyu⋅Azzouz, Faouzi⋅Mc Leod, Howard L⋅Borges-Gonzales, Silvana⋅Nguyen, Anne⋅Skaar, Todd C⋅Desta, Zeruesenay⋅Sweeney, Christopher J and Flockhart, David A
Journal of biopharmaceutical statistics, vol. 18, (no. 6), pp. 1150-77, 2008. | Journal Article
 
Association of polymorphisms of angiogenesis genes with breast cancer
Schneider, Bryan P⋅Radovich, Milan⋅Sledge, George W⋅Robarge, Jason D⋅Li, Lang⋅Storniolo, Anna M⋅Lemler, Suzanne⋅Nguyen, Anne T⋅Hancock, Bradley A⋅Stout, Michael⋅Skaar, Todd and Flockhart, David A
Breast Cancer Research and Treatment, vol. 111, (no. 1), pp. 157-63, Sep 2008. | Journal Article
 
Estrogen receptor genotypes influence hot flash prevalence and composite score before and after tamoxifen therapy.
Jin, Yan⋅Jin, Yan⋅Jin, Yan⋅Hayes, Daniel⋅Hayes, Daniel F⋅Hayes, Daniel⋅Li, Lang⋅Li, Lang⋅Li, Lang⋅Robarge, Jason D⋅Robarge, Jason⋅Robarge, Jason⋅Skaar, Todd C⋅Skaar, Todd⋅Skaar, Todd⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Nguyen, Anne⋅Nguyen, Anne⋅Nguyen, Anne⋅Schott, Anne⋅Schott, Anne⋅Schott, Anne⋅Hayden, Jill⋅Hayden, Jill⋅Hayden, Jill⋅Lemler, Suzanne⋅Lemler, Suzanne⋅Lemler, Suzanne⋅Storniolo, Anna⋅Storniolo, Anna⋅Storniolo, Anna M⋅Flockhart, David⋅Flockhart, David⋅Flockhart, David A⋅Stearns, Vered⋅Stearns, Vered and Stearns, Vered
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 26, (no. 36), pp. 5849-54, 2008/Dec/20. | Journal Article
 
Estrogen receptor genotypes, menopausal status, and the lipid effects of tamoxifen.
Ntukidem, N I⋅Nguyen, A T⋅Stearns, Vered⋅Rehman, M⋅Schott, A⋅Skaar, Todd C⋅Jin, Y⋅Blanche, P⋅Li, L⋅Lemler, S⋅Hayden, J⋅Krauss, Ronald M⋅Desta, Z⋅Flockhart, D A and Hayes, Daniel F
Clinical pharmacology and therapeutics, vol. 83, (no. 5), pp. 702-10, 2008/May. | Journal Article
 
MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma.
Tinder, Teresa L⋅Subramani, Durai B⋅Basu, Gargi D⋅Bradley, Judy M⋅Schettini, Jorge⋅Million, Arefayene⋅Skaar, Todd C and Mukherjee, Pinku
Journal of immunology (Baltimore, Md. : 1950), vol. 181, (no. 5), pp. 3116-25, 2008/Sep/1. | Journal Article