189 Publications (Page 3 of 8)
2016
Effects of exemestane and letrozole therapy on plasma concentrations of estrogens in a randomized trial of postmenopausal women with breast cancer.
Robarge, Jason D⋅Desta, Zereunesay⋅Nguyen, Anne T⋅Li, Lang⋅Hertz, Daniel⋅Rae, James M⋅Hayes, Daniel F⋅Storniolo, Anna M⋅Stearns, Vered⋅Flockhart, David A⋅Skaar, Todd C and Henry, N Lynn
Breast cancer research and treatment, December 9, 2016. | Journal Article
 
ESR1 and PGR Polymorphisms Affect Estrogen and Progesterone Receptor Expression in Breast Tumors.
Hertz, Daniel L⋅Hertz, D.L.⋅Hertz, Daniel L⋅Hertz, Daniel L⋅Henry, N Lynn⋅Henry, N Lynn⋅Henry, N Lynn⋅Henry, N.L.⋅Kidwell, Kelley M⋅Kidwell, K.M.⋅Kidwell, Kelley M⋅Kidwell, Kelley M⋅Thomas, Dafydd⋅Thomas, Dafydd⋅Thomas, D.⋅Thomas, Dafydd⋅Goddard, A.⋅Goddard, Audrey⋅Goddard, Audrey⋅Goddard, Audrey⋅Azzouz, Faouzi⋅Azzouz, Faouzi⋅Azzouz, F.⋅Azzouz, Faouzi⋅Speth, Kelly⋅Speth, Kelly⋅Speth, Kelly⋅Speth, K.⋅Li, Lang⋅Li, L.⋅Li, Lang⋅Li, Lang⋅Banerjee, Mousumi⋅Banerjee, Mousumi⋅Banerjee, Mousumi⋅Banerjee, M.⋅Thibert, J.N.⋅Thibert, Jacklyn N⋅Thibert, Jacklyn N⋅Thibert, Jacklyn N⋅Kleer, Celina G⋅Kleer, C.G.⋅Kleer, Celina G⋅Kleer, Celina G⋅Stearns, Vered⋅Stearns, Vered⋅Stearns, V.⋅Stearns, Vered⋅Hayes, D.F.⋅Hayes, Daniel F⋅Hayes, Daniel F⋅Hayes, Daniel F⋅Skaar, Todd C⋅Skaar, T.C.⋅Skaar, Todd C⋅Skaar, Todd⋅Rae, James M⋅Rae, James M⋅Rae, J.M. and Rae, James M
Physiological genomics, pp. physiolgenomics.00065.2016, August 19, 2016. | Journal Article
 
Identification of rifampin-regulated functional modules and related microRNAs in human hepatocytes based on the protein interaction network.
Li, Jin⋅Wang, Ying⋅Wang, Lei⋅Dai, Xuefeng⋅Cong, Wang⋅Feng, Weixing⋅Xu, Chengzhen⋅Deng, Yulin⋅Wang, Yue⋅Skaar, Todd C⋅Liang, Hong and Liu, Yunlong
BMC genomics, vol. 17, pp. 517. | Journal Article
 
Implementation of a pharmacogenomics consult service to support the INGENIOUS trial.
Eadon, M T⋅Desta, Z⋅Levy, K D⋅Decker, B S⋅Pierson, R C⋅Pratt, V M⋅Callaghan, J T⋅Rosenman, M B⋅Carpenter, J S⋅Holmes, A M⋅McDonald, C A⋅Benson, E A⋅Patil, A S⋅Vuppalanchi, R⋅Gufford, B T⋅Dave, N⋅Robarge, J D⋅Hyder, M A⋅Haas, D M⋅Kreutz, R P⋅Dexter, P R⋅Skaar, T C and Flockhart, D A
Clinical pharmacology and therapeutics, vol. 100, (no. 1), pp. 63-66, July 2016. | Journal Article
 
Inhibition of CYP2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers.
Desta, Zeruesenay⋅Metzger, Ingrid F⋅Thong, Nancy⋅Lu, Jessica B L⋅Callaghan, John T⋅Skaar, Todd C⋅Flockhart, David A and Galinsky, Raymond E
Antimicrobial agents and chemotherapy, September 6, 2016. | Journal Article
 
Inhibition of Cytochrome P450 2B6 Activity by Voriconazole Profiled Using Efavirenz Disposition in Healthy Volunteers
Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Metzger, Ingrid F⋅Thong, Nancy⋅Thong, Nancy⋅Thong, Nancy⋅Lu, Jessica B L⋅Lu, Jessica B L⋅Lu, Jessica B L⋅Callaghan, John T⋅Callaghan, John T⋅Callaghan, John T⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Flockhart, David A⋅Flockhart, David A⋅Flockhart, David A⋅Galinsky, Raymond E⋅Galinsky, Raymond E and Galinsky, Raymond E
Antimicrobial agents and chemotherapy, vol. 60, (no. 11), pp. 6822, 2016-11-00. | Journal Article
 
Patient-Reported Outcomes and Early Discontinuation in Aromatase Inhibitor-Treated Postmenopausal Women With Early Stage Breast Cancer.
Kadakia, Kunal C⋅Kadakia, K.C.⋅Kadakia, Kunal C⋅Snyder, Claire F⋅Snyder, C.F.⋅Snyder, Claire F⋅Kidwell, K.M.⋅Kidwell, Kelley M⋅Kidwell, Kelley M⋅Seewald, Nicholas J⋅Seewald, Nicholas J⋅Seewald, N.J.⋅Flockhart, D.A.⋅Flockhart, David A⋅Flockhart, David A⋅Skaar, T.C.⋅Skaar, Todd C⋅Skaar, Todd C⋅Desta, Zereunesay⋅Desta, Z.⋅Desta, Zereunesay⋅Rae, James M⋅Rae, J.M.⋅Rae, James M⋅Otte, Julie L⋅Otte, J.L.⋅Otte, Julie L⋅Carpenter, Janet S⋅Carpenter, J.S.⋅Carpenter, Janet S⋅Storniolo, Anna M⋅Storniolo, A.M.⋅Storniolo, Anna M⋅Hayes, Daniel F⋅Hayes, D.F.⋅Hayes, Daniel F⋅Stearns, Vered⋅Stearns, Vered⋅Stearns, V.⋅Henry, N. Lynn⋅Henry, N Lynn and Lynn Henry, N.
The oncologist, vol. 21, (no. 5), pp. 539-546, May 2016. | Journal Article
 
Polymorphisms in drug-metabolizing enzymes and steady-state exemestane concentration in postmenopausal patients with breast cancer.
Hertz, D L⋅Kidwell, K M⋅Seewald, N J⋅Gersch, C L⋅Desta, Z⋅Flockhart, D A⋅Storniolo, A-M⋅Stearns, V⋅Skaar, T C⋅Hayes, D F⋅Henry, N L and Rae, J M
The pharmacogenomics journal, August 23, 2016. | Journal Article
 
Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers.
Cho, Doo-Yeoun⋅Shen, Joan H Q⋅Lemler, Suzanne M⋅Skaar, Todd C⋅Li, Lang⋅Blievernicht, Julia⋅Zanger, Ulrich M⋅Kim, Kwon-Bok⋅Shin, Jae-Gook⋅Flockhart, David A and Desta, Zeruesenay
Drug metabolism and pharmacokinetics, vol. 31, (no. 2), pp. 107-116, April 2016. | Journal Article
 
Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human Hepatocytes.
Benson, Eric A⋅Benson, Eric A⋅Benson, Eric A.⋅Eadon, Michael T⋅Eadon, Michael T.⋅Eadon, Michael T⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Liu, Yunlong⋅Liu, Yunlong⋅Liu, Yunlong⋅Lin, Hai⋅Lin, Hai⋅Lin, Hai⋅Burgess, Kimberly S⋅Burgess, Kimberly S⋅Burgess, Kimberly S.⋅Segar, Matthew W⋅Segar, Matthew W⋅Segar, Matthew W.⋅Gaedigk, Andrea⋅Gaedigk, Andrea⋅Gaedigk, Andrea⋅Skaar, Todd C.⋅Skaar, Todd C and Skaar, Todd C
Frontiers in pharmacology, vol. 7, pp. 111, 2016. | Journal Article
 
Sleep disorders in breast cancer survivors
Otte, Julie⋅Otte, Julie⋅Otte, J.L.⋅Davis, Lorie⋅Davis, Lorie⋅Davis, L.⋅Carpenter, Janet⋅Carpenter, J.S.⋅Carpenter, Janet⋅Krier, C.⋅Krier, Connie⋅Krier, Connie⋅Skaar, T.C.⋅Skaar, Todd⋅Skaar, Todd⋅Rand, Kevin⋅Rand, Kevin⋅Rand, K.L.⋅Weaver, Michael⋅Weaver, Michael⋅Weaver, M.⋅Landis, C.⋅Landis, Carol⋅Landis, Carol⋅Chernyak, Yelena⋅Chernyak, Yelena⋅Chernyak, Y.⋅Manchanda, Shalini⋅Manchanda, Shalini and Manchanda, S.
Supportive Care in Cancer, vol. 24, (no. 10), pp. 4197-4205, Oct 2016. | Journal Article
 
Synthesis of Triphenylethylene Bisphenols as Aromatase Inhibitors That Also Modulate Estrogen Receptors.
Lv, Wei⋅Liu, Jinzhong⋅Skaar, Todd C⋅O'Neill, Elizaveta⋅Yu, Ge⋅Flockhart, David A and Cushman, Mark
Journal of medicinal chemistry, vol. 59, (no. 1), pp. 157-170, January 14, 2016. | Journal Article
 
TOLERABILITY OF ACETYLCHOLINESTERASE INHIBITORS BY CYP2D6 ACTIVITY
Campbell, Noll⋅Campbell, Noll⋅Campbell, Noll⋅Perkins, Tony⋅Perkins, Tony⋅Perkins, Tony⋅Skaar, Todd⋅Skaar, Todd⋅Skaar, Todd⋅Boustani, Malaz⋅Boustani, Malaz and Boustani, Malaz
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, vol. 12, (no. 7), pp. P427, 2016. | Journal Article
2015
Age-Related Changes in MicroRNA Expression and Pharmacogenes in Human Liver.
Burgess, K S⋅Burgess, Ks⋅Philips, S⋅Philips, S⋅Benson, E A⋅Benson, EA⋅Desta, Z⋅Desta, Z⋅Gaedigk, A⋅Gaedigk, A⋅Gaedigk, R⋅Gaedigk, R⋅Segar, M W⋅Segar, MW⋅Liu, Y⋅Liu, Y⋅Skaar, TC and Skaar, T C
Clinical pharmacology and therapeutics, vol. 98, (no. 2), pp. 205-215, August 2015. | Journal Article
 
AMPD1 polymorphism and response to regadenoson.
Saab, Rayan⋅Saab, Rayan⋅Zouk, Aline N⋅Zouk, Aline N⋅Mastouri, Ronald⋅Mastouri, Ronald⋅Skaar, Todd C⋅Skaar, Todd C⋅Philips, Santosh⋅Philips, Santosh⋅Kreutz, Rolf P and Kreutz, Rolf P
Pharmacogenomics, vol. 16, (no. 16), pp. 1807-1815, November 2015. | Journal Article
 
Associations between genetic variants and the effect of letrozole and exemestane on bone mass and bone turnover.
Oesterreich, Steffi⋅Oesterreich, Steffi⋅Oesterreich, Steffi⋅Oesterreich, Steffi⋅Henry, N⋅Henry, N L⋅Henry, N Lynn⋅Henry, N⋅Kidwell, Kelley⋅Kidwell, Kelley M⋅Kidwell, Kelley M⋅Kidwell, Kelley⋅Van Poznak, Catherine H⋅Van Poznak, Catherine⋅Van Poznak, Catherine⋅Van Poznak, Catherine H⋅Skaar, Todd⋅Skaar, Todd⋅Skaar, Todd C⋅Skaar, Todd C⋅Dantzer, Jessica⋅Dantzer, Jessica⋅Dantzer, Jessica⋅Dantzer, Jessica⋅Li, Lang⋅Li, Lang⋅Li, Lang⋅Li, Lang⋅Hangartner, Thomas⋅Hangartner, Thomas⋅Hangartner, Thomas N⋅Hangartner, Thomas N⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Peacock, Munro⋅Nguyen, Anne⋅Nguyen, Anne⋅Nguyen, Anne T⋅Nguyen, Anne T⋅Rae, James⋅Rae, James⋅Rae, James M⋅Rae, James M⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Desta, Zeruesenay⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Storniolo, Anna M⋅Storniolo, Anna⋅Storniolo, Anna M⋅Storniolo, Anna⋅Stearns, Vered⋅Stearns, Vered⋅Stearns, Vered⋅Stearns, Vered⋅Hayes, Daniel F⋅Hayes, Daniel⋅Hayes, Daniel⋅Hayes, Daniel F⋅Flockhart, David A⋅Flockhart, David⋅Flockhart, David and Flockhart, David A
Breast cancer research and treatment, vol. 154, (no. 2), pp. 263-273, November 2015. | Journal Article
 
A translational bioinformatic approach in identifying and validating an interaction between Vitamin A and CYP19A1.
Philips, Santosh⋅Philips, Santosh⋅Philips, Santosh⋅Zhou, Jing⋅Zhou, Jing⋅Zhou, Jing⋅Li, Zhigao⋅Li, Zhigao⋅Li, Zhigao⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Li, Lang⋅Li, Lang and Li, Lang
BMC genomics, vol. 16 Suppl 7, pp. S17, 2015. | Journal Article
 
A two-week regimen of high-dose integrase inhibitors does not cause nephrotoxicity in mice.
Eadon, Michael T⋅Eadon, Michael T⋅Zhang, Hongji⋅Zhang, Hongji⋅Skaar, Todd C⋅Skaar, Todd C⋅Hato, Takashi⋅Hato, Takashi⋅Dagher, Pierre C⋅Dagher, Pierre C⋅Gupta, Samir K⋅Gupta, Samir K⋅Desta, Zeruesenay and Desta, Zeruesenay
Antiviral chemistry & chemotherapy, vol. 24, (no. 2), pp. 72-76, April 2015. | Journal Article
 
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot Study.
Benson, Eric A⋅Benson, Eric A⋅Skaar, Todd C⋅Skaar, Todd C⋅Liu, Yunlong⋅Liu, Yunlong⋅Nephew, Kenneth P⋅Nephew, Kenneth P⋅Matei, Daniela and Matei, Daniela
PloS one, vol. 10, (no. 10), pp. e0141279, 2015. | Journal Article
 
Characterization of hepatic enzyme activity in older adults with dementia: potential impact on personalizing pharmacotherapy.
Campbell, Noll L⋅Campbell, Noll L⋅Campbell, Noll L⋅Skaar, Todd C⋅Skaar, Todd C⋅Skaar, Todd C⋅Perkins, Anthony J⋅Perkins, Anthony J⋅Perkins, Anthony J⋅Gao, Sujuan⋅Gao, Sujuan⋅Gao, Sujuan⋅Li, Lang⋅Li, Lang⋅Li, Lang⋅Khan, Babar A⋅Khan, Babar A⋅Khan, Babar A⋅Boustani, Malaz A⋅Boustani, Malaz A and Boustani, Malaz A
Clinical interventions in aging, vol. 10, pp. 269-275, 2015. | Journal Article
 
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 and CYP2C19 Genotypes and Dosing of Selective Serotonin Reuptake Inhibitors.
Hicks, J.K.⋅Hicks, J K⋅Bishop, J.R.⋅Bishop, J R⋅Sangkuhl, K.⋅Sangkuhl, K⋅Muller, D.J.⋅Müller, D J⋅Ji, Y.⋅Ji, Y⋅Leckband, S G⋅Leckband, S.G.⋅Leeder, J S⋅Leeder, J.S.⋅Graham, R L⋅Graham, R.L.⋅Chiulli, D L⋅Chiulli, D.L.⋅LLerena, A.⋅LLerena, A⋅Skaar, T C⋅Skaar, T.C.⋅Scott, S.A.⋅Scott, S A⋅Stingl, J C⋅Stingl, J.C.⋅Klein, T.E.⋅Klein, T E⋅Caudle, K E⋅Caudle, K.E.⋅Gaedigk, A. and Gaedigk, A
Clinical pharmacology and therapeutics, vol. 98, (no. 2), pp. 127-134, August 2015. | Journal Article
 
Comparison of genotyping performance in DNA extracted from matched FFPE tumor, FFPE lymph node, and whole blood for pharmacogenetic analyses
Hertz, Daniel Louis⋅Kidwell, Kelley M⋅Thibert, Jacklyn N⋅Gersch, Christina L⋅Regan, Meredith M⋅Skaar, Todd C⋅Henry, Norah Lynn⋅Hayes, Daniel⋅Van Poznak, Catherine and Rae, James M
Journal of Clinical Oncology, vol. 33, (no. 15_suppl), pp. 1528, 2015-05-20. | Journal Article
 
Considerations for the Utility of the CPIC Guideline for CYP2D6 Genotype and Codeine Therapy
Crews, Kristine⋅Caudle, Kelly⋅Dunnenberger, Henry⋅Sadhasivam, Senthilkumar and Skaar, Todd
(pp. 775-776). May 2015
 
Considerations for the Utility of the CPIC Guideline for CYP2D6 Genotype and Codeine Therapy.
Crews, Kristine R⋅Crews, Kristine R⋅Caudle, Kelly E⋅Caudle, Kelly E⋅Dunnenberger, Henry M⋅Dunnenberger, Henry M⋅Sadhasivam, Senthilkumar⋅Sadhasivam, Senthilkumar⋅Skaar, Todd C and Skaar, Todd C
Clinical chemistry, vol. 61, (no. 5), pp. 775-776, May 2015. | Journal Article
 
Cypiripi: exact genotyping of CYP2D6 using high-throughput sequencing data.
Numanagić, Ibrahim⋅Malikić, Salem⋅Pratt, Victoria M⋅Skaar, Todd C⋅Flockhart, David A and Sahinalp, S Cenk
Bioinformatics (Oxford, England), vol. 31, (no. 12), pp. i27-i34, June 15, 2015. | Journal Article