77 Publications (Page 1 of 4)
2016
DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-indole Antibiotics
Opperman, Timothy J⋅Kwasny, Steven M⋅Li, Jessica Bo⋅Lewis, Mark A⋅Aiello, Daniel⋅Williams, John D⋅Peet, Norton P⋅Moir, Donald T⋅Bowlin, Terry L and Long, Eric C
Antimicrobial agents and chemotherapy, vol. 60, (no. 12), pp. 7076, 2016-12-00. | Journal Article
2015
Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model
Tonsing-Carter, E.⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Tonsing-Carter, Eva⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, B.J.⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M Reza⋅Saadatzadeh, M.R.⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Ding, J.⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Ding, Jixin⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, H.⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Sinn, A.L.⋅Sinn, Anthony L⋅Sinn, Anthony L⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Peterman, K.M.⋅Peterman, Kacie M⋅Peterman, Kacie M⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, T.K.⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Spragins, Tiaishia K⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, Jayne M⋅Silver, J.M.⋅Silver, Jayne M⋅Silver, Jayne M⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, A.A.⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Sprouse, Alyssa A⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, T.M.⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T.Z.⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Gunter, T Zachary⋅Long, Eric C⋅Long, E.C.⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Minto, R.E.⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Minto, Robert E⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, C.C.⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Marchal, Christophe C⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, Christopher N⋅Batuello, C.N.⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, A.R.⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Safa, Ahmad R⋅Hanenberg, Helmut⋅Hanenberg, H.⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Hanenberg, Helmut⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, Paul R⋅Territo, P.R.⋅Territo, Paul R⋅Territo, Paul R⋅Sandusky, G.E.⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Mayo, L.D.⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, Christine M⋅Eischen, C.M.⋅Eischen, Christine M⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, H.E.⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Shannon, Harlan E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, K.E.⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E and Pollok, Karen E
Molecular cancer therapeutics, vol. 14, (no. 12), pp. 2863, 2015-Dec. | Journal Article
2014
Abstract 2741: Sensitization of temozolomide-mediated glioblastoma cell death by targeting MDM2: Assessment of PD biomarkers, brain penetration, and efficacy in humanized orthotopic xenograft models
Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Wang, Haiyan⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Cai, Shanbao⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Bailey, Barbara J⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Gelbert, Lawrence M⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Saadatzadeh, M. Reza⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Cohen Gadol, Aaron A⋅Cohen-Gadol, Aaron A⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Sarkaria, Jann N⋅Territo, Paul⋅Territo, Paul⋅Territo, Paul⋅Territo, Paul⋅Territo, Paul⋅Territo, Paul⋅Territo, Paul⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Georgiadis, Taxiarchis M⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Gunter, T. Zachary⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Meroueh, Samy⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Jones, David R⋅Jones, David R⋅Jones, David R⋅Jones, David R⋅Jones, David R⋅Jones, David R⋅Jones, David R⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Mayo, Lindsey D⋅Harlan, Shannon⋅Harlan, Shannon⋅Harlan, Shannon⋅Harlan, Shannon⋅Harlan, Shannon⋅Harlan, Shannon⋅Harlan, Shannon⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E⋅Pollok, Karen E and Pollok, Karen E
Cancer Research, vol. 74, (no. 19 Supplement), pp. 2741, 2014-10-01. | Journal Article
 
DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO 5 : Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds
Lewis, Mark⋅Williams, Katie⋅Fang, Ya-Yin⋅Schultz, Franklin and Long, Eric
Current Bioactive Compounds, vol. 10, (no. 1), pp. 20, 2014-March. | Journal Article
 
DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds.
Lewis, Mark A⋅Williams, Katie M⋅Fang, Ya Yin⋅Schultz, Franklin A and Long, Eric C
Current bioactive compounds, vol. 10, (no. 1), pp. 13-20, 2014. | Journal Article
 
Reactivity of Damaged Pyrimidines: DNA Cleavage via Hemiaminal Formation at the C4 Positions of the Saturated Thymine of Spore Photoproduct and Dihydrouridine
Lin, Gengjie⋅Lin, Gengjie⋅Jian, Yajun⋅Jian, Yajun⋅Dria, Karl J⋅Dria, Karl J⋅Long, Eric C⋅Long, Eric C⋅Li, Lei and Li, Lei
Journal of the American Chemical Society, vol. 136, (no. 37), pp. 12946, 20140917. | Journal Article
 
Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates.
Garner, Matthew L⋅Georgiadis, Taxiarchis M⋅Li, Jessica B⋅Wang, Tianxiu and Long, Eric C
Amino acids, vol. 46, (no. 5), pp. 1297-303, 2014/May. | Journal Article
2012
A TRIBUTE TO A LIVING LEGEND
Long, Eric⋅Fenniri, Hicham⋅Martin, Olivier and Langer, Peter
Current Bioactive Compounds, vol. 8, (no. 3), pp. i, 2012-September. | Journal Article
2011
Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2.
Raches, David W⋅Raches, David W⋅Raches, David W⋅Xiao, Suhong⋅Xiao, Suhong⋅Xiao, Suhong⋅Kusumanchi, Praveen⋅Kusumanchi, Praveen⋅Kusumanchi, Praveen⋅Yalowitz, Joel⋅Yalowitz, Joel⋅Yalowitz, Joel⋅Sanghani, Paresh⋅Sanghani, Paresh⋅Sanghani, Paresh⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Antony, Aśok C⋅Antony, Asok C⋅Antony, Aśok C⋅Jayaram, Hiremagalur N⋅Jayaram, Hiremagalur N and Jayaram, Hiremagalur N
Medicinal chemistry (Shāriqah (United Arab Emirates)), vol. 7, (no. 6), pp. 718-26, 2011/Nov. | Journal Article
2010
Abstract 1963: Novel small molecule inhibitor of the endonuclease function of the APE1 DNA repair and redox signaling enzyme blocks proliferation and reduces viability of glioblastoma cells
Bapat, Aditi⋅Bapat, Aditi⋅Bapat, Aditi⋅Bapat, Aditi⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Luo, Meihua⋅Luo, Meihua⋅Luo, Meihua⋅Luo, Meihua⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Reed, April⋅Reed, April⋅Reed, April⋅Reed, April⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R⋅Kelley, Mark R⋅Kelley, Mark R and Kelley, Mark R
Cancer Research, vol. 70, (no. 8 Supplement), pp. 1963, 2010-04-15. | Journal Article
 
Genome-Targeted Drug Design: Understanding the Netropsin-DNA Interaction
Fang, Ya Yin⋅Morris, Vernon R⋅Lingani, Guy M⋅Long, Eric C and Southerland, William M
Open Conference Proceedings Journal, vol. 1, pp. 157-163, 2010. | Journal Article
 
Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
Bapat, Aditi⋅Bapat, Aditi⋅Glass, Lateca S⋅Glass, Lateca S⋅Luo, Meihua⋅Luo, Meihua⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Long, Eric C⋅Long, Eric C⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R and Kelley, Mark
The Journal of pharmacology and experimental therapeutics, vol. 334, (no. 3), pp. 988-98, 2010/Sep/1. | Journal Article
 
Properties of double-stranded oligonucleotides modified with lipophilic substituents.
Laing, Brian M⋅Barrow-Laing, Lisa⋅Harrington, Maureen⋅Long, Eric C and Bergstrom, Donald E
Bioconjugate chemistry, vol. 21, (no. 8), pp. 1537-44, 2010/Aug/18. | Journal Article
 
Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library
Glass, LaTeca S⋅Bapat, Aditi⋅Kelley, Mark R⋅Georgiadis, Millie M and Long, Eric C
Bioorganic and Medicinal Chemistry Letters, vol. 20, (no. 5), pp. 1685-1688, 2010. | Journal Article
2009
Crystal structure of a trypanocidal 4,4?-bisdiphenylamine bound to DNA
Glass, LaTeca⋅Glass, LaTeca⋅Nguyen, Binh⋅Nguyen, Binh⋅Goodwin, Kristie⋅Goodwin, Kristie⋅Dardonville, Christophe⋅Dardonville, Christophe⋅Wilson, W.⋅Wilson, W.⋅Long, Eric⋅Long, Eric⋅Georgiadis, Millie and Georgiadis, Millie
Biochemistry, vol. 48, (no. 25), pp. 5943, 20090630. | Journal Article
 
Crystal Structure of a Trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine Bound to DNA,
Glass, Lateca S⋅Nguyen, Binh⋅Goodwin, Kristie D⋅Dardonville, Christophe⋅Wilson, William D⋅Long, Eric C and Georgiadis, Millie M
Biochemistry (Washington), vol. 48, (no. 25), pp. 5943-5952, 2009. | Journal Article
 
Metal Complex−DNA Interactions Metal Complex−DNA Interactions . Edited by Nick Hadjiliadis (University of Ioannina, Greece) and Einar Sletten (University of Bergen, Norway). John Wiley & Sons, Ltd.: Chichester. 2009 . xx + 524 pp. $199.99. ISBN 978-1-4051-7629-3
Long, Eric C
Journal of the American Chemical Society, vol. 131, (no. 39), pp. 14125, 2009-10-07. | Journal Article
2008
Crystal structure of DNA-bound Cobleomycin [B.sub.2]: insights on intercalation and minor groove binding
Goodwin, Kristie⋅Goodwin, Kristie⋅Lewis, Mark⋅Lewis, Mark⋅Long, Eric⋅Long, Eric⋅Georgiadis, Millie and Georgiadis, Millie
Proceedings of the National Academy of Sciences of the United States, vol. 105, (no. 13), pp. 5052, 20080401. | Journal Article
 
Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Goodwin, Kristie D⋅Lewis, Mark A⋅Long, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 13), pp. 5052-6, 2008/Apr/1. | Journal Article
 
Crystal structure of DNA-bound Co(III)·bleomycin B₂: Insights on intercalation and minor groove binding.
Goodwin, Kristie D⋅Lewis, Mark A⋅Long, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America., vol. 105, (no. 13), pp. 5052-5056, 2008. | Journal Article
 
Crystal structure of DNA-bound Co(III)-bleomycin B^sub 2^: Insights on intercalation and minor groove binding
Goodwin, Kristie D⋅Lewis, Mark A⋅Long, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 13), Apr 1, 2008. | Journal Article
 
Fluorescence correlation spectroscopy of CdSe/ZnS quantum dot optical bioimaging probes with ultra-thin biocompatible coatings.
Murcia, Michael J⋅Shaw, David L⋅Long, Eric C and Naumann, Christoph A
Optics communications, vol. 281, (no. 7), pp. 1771-1780, April 1, 2008. | Journal Article
2007
DNA-fiber EPR investigation of the influence of amino-terminal residue stereochemistry on the DNA binding orientation of Cu(II).Gly-Gly-His-derived metallopeptides.
Hamada, Hirokazu⋅Abe, Yuko⋅Nagane, Ryoichi⋅Fang, Ya Yin⋅Lewis, Mark A⋅Long, Eric C and Chikira, Makoto
Journal of inorganic biochemistry, vol. 101, (no. 10), pp. 1529-36, 2007/Oct. | Journal Article
 
Influence of stereochemistry and redox potentials on the single- and double-strand DNA cleavage efficiency of Cu. and Ni.Lys-Gly-His-derived ATCUN metallopeptides
Jin, Yan⋅Lewis, Mark⋅Gokhale, Nikhil⋅Long, Eric and Cowan, J.A
Journal of the American Chemical Society, vol. 129, (no. 26), pp. 8353, 20070704. | Journal Article
 
Influence of Stereochemistry and Redox Potentials on the Single- and Double-Strand DNA Cleavage Efficiency of Cu(II)· and Ni(II)·Lys-Gly-His-Derived ATCUN Metallopeptides
Jin, Y.⋅Jin, Yan⋅Lewis, MA⋅Lewis, Mark A⋅Gokhale, NH⋅Gokhale, Nikhil H⋅Long, Eric C⋅Long, EC⋅Cowan, James A and Cowan, J. A
Journal of the American Chemical Society, vol. 129, (no. 26), pp. 8361, 20070704. | Journal Article