77 Publications (Page 1 of 4)
2016
DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-indole Antibiotics
Opperman, Timothy JKwasny, Steven MLi, Jessica BoLewis, Mark AAiello, DanielWilliams, John DPeet, Norton PMoir, Donald TBowlin, Terry L and Long, Eric C
Antimicrobial agents and chemotherapy, vol. 60, (no. 12), pp. 7076, 2016-12-00. | Journal Article
2015
Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model
Tonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, E.Tonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaTonsing-Carter, EvaBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, B.J.Saadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M RezaSaadatzadeh, M.R.Ding, JixinDing, J.Ding, JixinDing, JixinDing, JixinDing, JixinDing, JixinDing, JixinWang, HaiyanWang, HaiyanWang, H.Wang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanSinn, Anthony LSinn, Anthony LSinn, A.L.Sinn, Anthony LSinn, Anthony LSinn, Anthony LSinn, Anthony LSinn, Anthony LPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, Kacie MPeterman, K.M.Peterman, Kacie MSpragins, T.K.Spragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSpragins, Tiaishia KSilver, J.M.Silver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSilver, Jayne MSprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, Alyssa ASprouse, A.A.Sprouse, Alyssa AGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, T.M.Gunter, T ZacharyGunter, T.Z.Gunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyGunter, T ZacharyLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, E.C.Long, Eric CMinto, R.E.Minto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMinto, Robert EMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, Christophe CMarchal, C.C.Marchal, Christophe CBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, Christopher NBatuello, C.N.Safa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, Ahmad RSafa, A.R.Safa, Ahmad RSafa, Ahmad RSafa, Ahmad RHanenberg, HelmutHanenberg, HelmutHanenberg, H.Hanenberg, HelmutHanenberg, HelmutHanenberg, HelmutHanenberg, HelmutHanenberg, HelmutTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, Paul RTerrito, P.R.Territo, Paul RSandusky, George ESandusky, George ESandusky, George ESandusky, George ESandusky, G.E.Sandusky, George ESandusky, George ESandusky, George EMayo, L.D.Mayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DEischen, Christine MEischen, Christine MEischen, Christine MEischen, C.M.Eischen, Christine MEischen, Christine MEischen, Christine MEischen, Christine MShannon, Harlan EShannon, Harlan EShannon, Harlan EShannon, Harlan EShannon, H.E.Shannon, Harlan EShannon, Harlan EShannon, Harlan EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, K.E.Pollok, Karen EPollok, Karen E and Pollok, Karen E
Molecular cancer therapeutics, vol. 14, (no. 12), pp. 2863, 2015-Dec. | Journal Article
2014
Abstract 2741: Sensitization of temozolomide-mediated glioblastoma cell death by targeting MDM2: Assessment of PD biomarkers, brain penetration, and efficacy in humanized orthotopic xenograft models
Wang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanWang, HaiyanCai, ShanbaoCai, ShanbaoCai, ShanbaoCai, ShanbaoCai, ShanbaoCai, ShanbaoCai, ShanbaoBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JBailey, Barbara JGelbert, Lawrence MGelbert, Lawrence MGelbert, Lawrence MGelbert, Lawrence MGelbert, Lawrence MGelbert, Lawrence MGelbert, Lawrence MSaadatzadeh, M. RezaSaadatzadeh, M. RezaSaadatzadeh, M. RezaSaadatzadeh, M. RezaSaadatzadeh, M. RezaSaadatzadeh, M. RezaSaadatzadeh, M. RezaCohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen-Gadol, Aaron ACohen Gadol, Aaron ACohen-Gadol, Aaron ASarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NSarkaria, Jann NTerrito, PaulTerrito, PaulTerrito, PaulTerrito, PaulTerrito, PaulTerrito, PaulTerrito, PaulGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGeorgiadis, Taxiarchis MGunter, T. ZacharyGunter, T. ZacharyGunter, T. ZacharyGunter, T. ZacharyGunter, T. ZacharyGunter, T. ZacharyGunter, T. ZacharyMeroueh, SamyMeroueh, SamyMeroueh, SamyMeroueh, SamyMeroueh, SamyMeroueh, SamyMeroueh, SamyLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CLong, Eric CJones, David RJones, David RJones, David RJones, David RJones, David RJones, David RJones, David RMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DMayo, Lindsey DHarlan, ShannonHarlan, ShannonHarlan, ShannonHarlan, ShannonHarlan, ShannonHarlan, ShannonHarlan, ShannonPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen EPollok, Karen E and Pollok, Karen E
Cancer Research, vol. 74, (no. 19 Supplement), pp. 2741, 2014-10-01. | Journal Article
 
DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO 5 : Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds
Lewis, MarkWilliams, KatieFang, Ya-YinSchultz, Franklin and Long, Eric
Current Bioactive Compounds, vol. 10, (no. 1), pp. 20, 2014-March. | Journal Article
 
DNA Cleaving "Tandem-Array" Metallopeptides Activated With KHSO5: Towards the Development of Multi-Metallated Bioactive Conjugates and Compounds.
Lewis, Mark AWilliams, Katie MFang, Ya YinSchultz, Franklin A and Long, Eric C
Current bioactive compounds, vol. 10, (no. 1), pp. 13-20, 2014. | Journal Article
 
Reactivity of Damaged Pyrimidines: DNA Cleavage via Hemiaminal Formation at the C4 Positions of the Saturated Thymine of Spore Photoproduct and Dihydrouridine
Lin, GengjieLin, GengjieJian, YajunJian, YajunDria, Karl JDria, Karl JLong, Eric CLong, Eric CLi, Lei and Li, Lei
Journal of the American Chemical Society, vol. 136, (no. 37), pp. 12946, 20140917. | Journal Article
 
Solid-phase synthesis of amidine-substituted phenylbenzimidazoles and incorporation of this DNA binding and recognition motif into amino acid and peptide conjugates.
Garner, Matthew LGeorgiadis, Taxiarchis MLi, Jessica BWang, Tianxiu and Long, Eric C
Amino acids, vol. 46, (no. 5), pp. 1297-303, 2014/May. | Journal Article
2012
A TRIBUTE TO A LIVING LEGEND
Long, EricFenniri, HichamMartin, Olivier and Langer, Peter
Current Bioactive Compounds, vol. 8, (no. 3), pp. i, 2012-September. | Journal Article
2011
Cloning, expression and characterization of mouse (Mus musculus) nicotinamide 5'-mononucleotide adenylyltransferase-2.
Raches, David WRaches, David WRaches, David WXiao, SuhongXiao, SuhongXiao, SuhongKusumanchi, PraveenKusumanchi, PraveenKusumanchi, PraveenYalowitz, JoelYalowitz, JoelYalowitz, JoelSanghani, PareshSanghani, PareshSanghani, PareshLong, Eric CLong, Eric CLong, Eric CAntony, Aśok CAntony, Asok CAntony, Aśok CJayaram, Hiremagalur NJayaram, Hiremagalur N and Jayaram, Hiremagalur N
Medicinal chemistry (Shāriqah (United Arab Emirates)), vol. 7, (no. 6), pp. 718-26, 2011/Nov. | Journal Article
2010
Abstract 1963: Novel small molecule inhibitor of the endonuclease function of the APE1 DNA repair and redox signaling enzyme blocks proliferation and reduces viability of glioblastoma cells
Bapat, AditiBapat, AditiBapat, AditiBapat, AditiGlass, LaTeca SGlass, LaTeca SGlass, LaTeca SGlass, LaTeca SLuo, MeihuaLuo, MeihuaLuo, MeihuaLuo, MeihuaFishel, Melissa LFishel, Melissa LFishel, Melissa LFishel, Melissa LReed, AprilReed, AprilReed, AprilReed, AprilLong, Eric CLong, Eric CLong, Eric CLong, Eric CGeorgiadis, Millie MGeorgiadis, Millie MGeorgiadis, Millie MGeorgiadis, Millie MKelley, Mark RKelley, Mark RKelley, Mark R and Kelley, Mark R
Cancer Research, vol. 70, (no. 8 Supplement), pp. 1963, 2010-04-15. | Journal Article
 
Genome-Targeted Drug Design: Understanding the Netropsin-DNA Interaction
Fang, Ya YinMorris, Vernon RLingani, Guy MLong, Eric C and Southerland, William M
Open Conference Proceedings Journal, vol. 1, pp. 157-163, 2010. | Journal Article
 
Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.
Bapat, AditiBapat, AditiGlass, Lateca SGlass, Lateca SLuo, MeihuaLuo, MeihuaFishel, Melissa LFishel, Melissa LLong, Eric CLong, Eric CGeorgiadis, Millie MGeorgiadis, Millie MKelley, Mark and Kelley, Mark R
The Journal of pharmacology and experimental therapeutics, vol. 334, (no. 3), pp. 988-98, 2010/Sep/1. | Journal Article
 
Properties of double-stranded oligonucleotides modified with lipophilic substituents.
Laing, Brian MBarrow-Laing, LisaHarrington, MaureenLong, Eric C and Bergstrom, Donald E
Bioconjugate chemistry, vol. 21, (no. 8), pp. 1537-44, 2010/Aug/18. | Journal Article
 
Semi-automated high-throughput fluorescent intercalator displacement-based discovery of cytotoxic DNA binding agents from a large compound library
Glass, LaTeca SBapat, AditiKelley, Mark RGeorgiadis, Millie M and Long, Eric C
Bioorganic and Medicinal Chemistry Letters, vol. 20, (no. 5), pp. 1685-1688, 2010. | Journal Article
2009
Crystal structure of a trypanocidal 4,4?-bisdiphenylamine bound to DNA
Glass, LaTecaGlass, LaTecaNguyen, BinhNguyen, BinhGoodwin, KristieGoodwin, KristieDardonville, ChristopheDardonville, ChristopheWilson, W.Wilson, W.Long, EricLong, EricGeorgiadis, Millie and Georgiadis, Millie
Biochemistry, vol. 48, (no. 25), pp. 5943, 20090630. | Journal Article
 
Crystal Structure of a Trypanocidal 4,4'-Bis(imidazolinylamino)diphenylamine Bound to DNA,
Glass, Lateca SNguyen, BinhGoodwin, Kristie DDardonville, ChristopheWilson, William DLong, Eric C and Georgiadis, Millie M
Biochemistry (Washington), vol. 48, (no. 25), pp. 5943-5952, 2009. | Journal Article
 
Metal Complex−DNA Interactions Metal Complex−DNA Interactions . Edited by Nick Hadjiliadis (University of Ioannina, Greece) and Einar Sletten (University of Bergen, Norway). John Wiley & Sons, Ltd.: Chichester. 2009 . xx + 524 pp. $199.99. ISBN 978-1-4051-7629-3
Long, Eric C
Journal of the American Chemical Society, vol. 131, (no. 39), pp. 14125, 2009-10-07. | Journal Article
2008
Crystal structure of DNA-bound Cobleomycin [B.sub.2]: insights on intercalation and minor groove binding
Goodwin, KristieGoodwin, KristieLewis, MarkLewis, MarkLong, EricLong, EricGeorgiadis, Millie and Georgiadis, Millie
Proceedings of the National Academy of Sciences of the United States, vol. 105, (no. 13), pp. 5052, 20080401. | Journal Article
 
Crystal structure of DNA-bound Co(III) bleomycin B2: Insights on intercalation and minor groove binding.
Goodwin, Kristie DLewis, Mark ALong, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 13), pp. 5052-6, 2008/Apr/1. | Journal Article
 
Crystal structure of DNA-bound Co(III)·bleomycin B₂: Insights on intercalation and minor groove binding.
Goodwin, Kristie DLewis, Mark ALong, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America., vol. 105, (no. 13), pp. 5052-5056, 2008. | Journal Article
 
Crystal structure of DNA-bound Co(III)-bleomycin B^sub 2^: Insights on intercalation and minor groove binding
Goodwin, Kristie DLewis, Mark ALong, Eric C and Georgiadis, Millie M
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 13), Apr 1, 2008. | Journal Article
 
Fluorescence correlation spectroscopy of CdSe/ZnS quantum dot optical bioimaging probes with ultra-thin biocompatible coatings.
Murcia, Michael JShaw, David LLong, Eric C and Naumann, Christoph A
Optics communications, vol. 281, (no. 7), pp. 1771-1780, April 1, 2008. | Journal Article
2007
DNA-fiber EPR investigation of the influence of amino-terminal residue stereochemistry on the DNA binding orientation of Cu(II).Gly-Gly-His-derived metallopeptides.
Hamada, HirokazuAbe, YukoNagane, RyoichiFang, Ya YinLewis, Mark ALong, Eric C and Chikira, Makoto
Journal of inorganic biochemistry, vol. 101, (no. 10), pp. 1529-36, 2007/Oct. | Journal Article
 
Influence of stereochemistry and redox potentials on the single- and double-strand DNA cleavage efficiency of Cu. and Ni.Lys-Gly-His-derived ATCUN metallopeptides
Jin, YanLewis, MarkGokhale, NikhilLong, Eric and Cowan, J.A
Journal of the American Chemical Society, vol. 129, (no. 26), pp. 8353, 20070704. | Journal Article
 
Influence of Stereochemistry and Redox Potentials on the Single- and Double-Strand DNA Cleavage Efficiency of Cu(II)· and Ni(II)·Lys-Gly-His-Derived ATCUN Metallopeptides
Jin, Y.Jin, YanLewis, MALewis, Mark AGokhale, NHGokhale, Nikhil HLong, Eric CLong, ECCowan, James A and Cowan, J. A
Journal of the American Chemical Society, vol. 129, (no. 26), pp. 8361, 20070704. | Journal Article