267 Publications (Page 5 of 11)
2003
Timing and duration of administration are crucial for antiinfarct effect of AMP 579 infused at reperfusion in rabbit heart.Xu, Zhelong⋅Downey, James M and Cohen, Michael VHeart disease (Hagerstown, Md.), vol. 5, (no. 6), pp. 368-71, 2003 Nov-Dec.
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2002
Acetylcholine leads to free radical production dependent on K(ATP) channels, G(i) proteins, phosphatidylinositol 3-kinase and tyrosine kinase.Oldenburg, Olaf⋅Qin, Qining⋅Sharma, Ana R⋅Cohen, Michael V⋅Downey, James M and Benoit, Joseph NCardiovascular research, vol. 55, (no. 3), pp. 544-52, 2002/Aug/15.
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ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinasesKrieg, Thomas⋅Qin, Qining⋅McIntosh, Elizabeth C⋅Cohen, Michael and Downey, James MAmerican Journal of Physiology, vol. 52, (no. 6), pp. H2322-H2330, Dec 2002.
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ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.Krieg, Thomas⋅Qin, Qining⋅McIntosh, Elizabeth C⋅Cohen, Michael V and Downey, James MAmerican journal of physiology. Heart and circulatory physiology, vol. 283, (no. 6), pp. H2322-30, 2002/Dec.
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Dose-response relationships of the protective and antiprotective effects of acute ethanol exposure in isolated rabbit hearts.
Krenz, Maike⋅Yang, Xi-Ming⋅Qin, Qining⋅Downey, James M and Cohen, Michael V
Heart disease (Hagerstown, Md.), vol. 4, (no. 5), pp. 276-81, 2002 Sep-Oct. | Journal Article
Mitochondrial K(ATP) channels: role in cardioprotection.Oldenburg, Olaf⋅Cohen, Michael V⋅Yellon, Derek and Downey, James MCardiovascular research, vol. 55, (no. 3), pp. 429-37, 2002/Aug/15.
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Opening of ATP-sensitive potassium channels causes generation of free radicals in vascular smooth muscle cells.Krenz, Maike⋅Krenz, Maike⋅Oldenburg, Olaf⋅Oldenburg, Olaf⋅Wimpee, Holly⋅Wimpee, Holly⋅Cohen, Michael V⋅Cohen, Michael V⋅Garlid, Keith D⋅Garlid, Keith D⋅Critz, Stuart D⋅Critz, Stuart D⋅Downey, James M⋅Downey, James M⋅Benoit, Joseph N and Benoit, Joseph NBasic research in cardiology, vol. 97, (no. 5), pp. 365-73, 2002/Sep.
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Phosphatidylinositol 3-kinase/AKT pathway contributes to ischemic preconditioning in isolated rabbit heart
Jlao, Zhe⋅Gorodnya, Olena⋅Downey, James and Fan, Tai-Hwang
Journal of the American College of Cardiology, vol. 39, pp. 278, Mar 6, 2002. | Journal Article
Preconditioning one myocardial region does not neccessarily precondition the whole rabbit heartNakano, Atsushi⋅Heusch, Gerd⋅Cohen, Michael and Downey, James(pp. 35-9). Jan 2002
Preconditioning one myocardial region does not neccessarily precondition the whole rabbit heart.Nakano, Atsushi⋅Heusch, Gerd⋅Cohen, Michael V and Downey, James MBasic research in cardiology, vol. 97, (no. 1), pp. 35-9, 2002/Jan.
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Protection from AMP 579 can be added to that from either cariporide or ischemic preconditioning in ischemic rabbit heart.Xu, Zhelong⋅Jiao, Zhe⋅Cohen, Michael V and Downey, James MJournal of cardiovascular pharmacology, vol. 40, (no. 4), pp. 510-8, 2002/Oct.
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Spotlight on preconditioning.
Yellon, Derek and Downey, James M
Cardiovascular research, vol. 55, (no. 3), pp. 425-8, 2002/Aug/15. | Journal Article
The protective and anti-protective effects of ethanol in a myocardial infarct model.Krenz, Maike⋅Cohen, Michael V and Downey, James MAnnals of the New York Academy of Sciences, vol. 957, pp. 103-14, 2002/May.
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The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.Yue, Yuankun⋅Qin, Qining⋅Cohen, Michael V⋅Downey, James M and Critz, Stuart DCardiovascular research, vol. 55, (no. 3), pp. 681-9, 2002/Aug/15.
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Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning.Gelpi, Ricardo J⋅Morales, Celina⋅Cohen, Michael V and Downey, James MBasic research in cardiology, vol. 97, (no. 1), pp. 40-6, 2002/Jan.
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2001
Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channelsCohen, Michael⋅Yang, Xi-Ming⋅Liu, Guang S⋅Heusch, Gerd and Downey, James MCirculation Research, vol. 89, (no. 3), pp. 273-8, Aug 3, 2001.
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Acute alcohol-induced protection against infarction in rabbit hearts: differences from and similarities to ischemic preconditioning.
Krenz, M⋅Baines, C P⋅Heusch, Gerd⋅Downey, James M and Cohen, M V
Journal of molecular and cellular cardiology, vol. 33, (no. 11), pp. 2015-22, 2001/Nov. | Journal Article
Acute ethanol exposure fails to elicit preconditioning-like protection in in situ rabbit hearts because of its continued presence during ischemia.Krenz, M⋅Baines, C P⋅Yang, X M⋅Heusch, Gerd⋅Cohen, Michael V and Downey, James MJournal of the American College of Cardiology, vol. 37, (no. 2), pp. 601-7, 2001/Feb.
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Amp 579 reduces contracture and limits infarction in rabbit heart by activating adenosine A2 receptors.
Xu, Z⋅Downey, James M and Cohen, M V
Journal of cardiovascular pharmacology, vol. 38, (no. 3), pp. 474-81, 2001/Sep. | Journal Article
Attenuation of oxidant stress during reoxygenation by AMP 579 in cardiomyocytesXu, Zhelong⋅Cohen, Michael⋅Downey, James M⋅Hoek, Terry L and Yao, ZhenhaiAmerican Journal of Physiology, vol. 50, (no. 6), pp. H2585-H2589, Dec 2001.
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Attenuation of oxidant stress during reoxygenation by AMP 579 in cardiomyocytes.Xu, Zhelong⋅Cohen, Michael V⋅Downey, James M⋅Vanden Hoek, T L and Yao, ZAmerican journal of physiology. Heart and circulatory physiology, vol. 281, (no. 6), pp. H2585-9, 2001/Dec.
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Menadione mimics the infarct-limiting effect of preconditioning in isolated rat heartsYue, Yuankun⋅Krenz, Maike⋅Cohen, Michael⋅Downey, James M and Critz, Stuart DAmerican Journal of Physiology, vol. 50, (no. 2), pp. H590-H595, Aug 2001.
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Menadione mimics the infarct-limiting effect of preconditioning in isolated rat hearts.Yue, Y⋅Krenz, M⋅Cohen, Michael V⋅Downey, James M and Critz, Stuart DAmerican journal of physiology. Heart and circulatory physiology, vol. 281, (no. 2), pp. H590-5, 2001/Aug.
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Mitochondrial K(ATP)channel opening during index ischemia and following myocardial reperfusion in ischemic rat hearts.
Downey, James M and Cohen, M V
Journal of molecular and cellular cardiology, vol. 33, (no. 4), pp. 651-3, 2001/Apr. | Journal Article
Signal transduction of ischemic preconditioning.Schulz, R⋅Cohen, Michael V⋅Behrends, M⋅Downey, James M and Heusch, GCardiovascular research, vol. 52, (no. 2), pp. 181-98, 2001/Nov.
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