267 Publications (Page 3 of 11)
2008
Redox signaling at reperfusion is required for protection from ischemic preconditioning but not from a direct PKC activator.
Liu, Yanping⋅Yang, Xi-Ming⋅Iliodromitis, Efstathios K⋅Kremastinos, Dimitrios T⋅Dost, Turhan⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 103, (no. 1), pp. 54-9, 2008/Jan. | Journal Article
 
Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning
Dost, Turhan⋅Cohen, Michael and Downey, James M
Basic Research in Cardiology, vol. 103, (no. 4), pp. 378-84, Jun 2008. | Journal Article
2007
Bypassing big pharma.
Downey, James M and Cohen, Michael V
Circulation, vol. 116, (no. 12), pp. 1344-5, 2007/Sep/18. | Journal Article
 
Cardioprotection: spotlight on PKG
Cohen, Michael and Downey, James M
British Journal of Pharmacology, vol. 152, (no. 6), pp. 833-4, Nov 2007. | Journal Article
 
Nicorandil opens mitochondrial K(ATP) channels not only directly but also through a NO-PKG-dependent pathway.
Kuno, Atsushi⋅Critz, Stuart D⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 102, (no. 1), pp. 73-9, 2007/Jan. | Journal Article
 
Preconditioning-mimetics bradykinin and DADLE activate PI3-kinase through divergent pathways.
Cohen, Michael V⋅Philipp, Sebastian⋅Krieg, Thomas⋅Cui, Lin⋅Kuno, Atsushi⋅Solodushko, Viktoriya and Downey, James M
Journal of molecular and cellular cardiology, vol. 42, (no. 4), pp. 842-51, 2007/Apr. | Journal Article
 
Protecting the acutely ischemic myocardium beyond reperfusion therapies: are we any closer to realizing the dream of infarct size elimination?
Tissier, R⋅Cohen, Michael V and Downey, James M
Archives des maladies du coeur et des vaisseaux, vol. 100, (no. 9), pp. 794-802, 2007/Sep. | Journal Article
 
Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.
Kuno, Atsushi⋅Kuno, Atsushi⋅Critz, Stuart D⋅Critz, Stuart⋅Cui, Lin⋅Cui, Lin⋅Solodushko, Victoriya⋅Solodushko, Victoriya⋅Yang, Xi-Ming⋅Yang, Xi-Ming⋅Krahn, Thomas⋅Krahn, Thomas⋅Albrecht, Barbara⋅Albrecht, Barbara⋅Philipp, Sebastian⋅Philipp, Sebastian⋅Cohen, Michael V⋅Cohen, Michael⋅Downey, James M and Downey, James
Journal of molecular and cellular cardiology, vol. 43, (no. 3), pp. 262-71, 2007/Sep. | Journal Article
 
Signaling pathways in ischemic preconditioning.
Downey, James M⋅Davis, Amanda M and Cohen, Michael V
Heart failure reviews, vol. 12, (no. 3-4), pp. 181-8, 2007/Dec. | Journal Article
 
The pH hypothesis of postconditioning: staccato reperfusion reintroduces oxygen and perpetuates myocardial acidosis.
Cohen, Michael V⋅Yang, Xi-Ming and Downey, James M
Circulation, vol. 115, (no. 14), pp. 1895-903, 2007/Apr/10. | Journal Article
 
Total liquid ventilation provides ultra-fast cardioprotective cooling.
Tissier, Renaud⋅Hamanaka, Kazutoshi⋅Kuno, Atsushi⋅Parker, James C⋅Cohen, Michael V and Downey, James M
Journal of the American College of Cardiology, vol. 49, (no. 5), pp. 601-5, 2007/Feb/6. | Journal Article
2006
AMISTAD trials: possible reasons for lack of success.
Cohen, Michael V and Downey, James M
Journal of the American College of Cardiology, vol. 47, (no. 6), pp. 1236; author reply 1236-7, 2006/Mar/21. | Journal Article
 
AMISTAD Trials: Possible Reasons for Lack of Success
Cohen, Michael and Downey, James
(pp. 1236). Mar 21, 2006
 
A really radical observation
Downey, James M and Cohen, Michael V
Basic Research in Cardiology, vol. 101, (no. 2), pp. 190-1, Mar 2006. | Journal Article
 
A really radical observation--a comment on Penna et al. in Basic Res Cardiol (2006) 101:180-189.
Downey, James M and Cohen, Michael V
Basic research in cardiology, vol. 101, (no. 2), pp. 190-1, 2006/Mar. | Journal Article
 
[ATP-dependent K+channels and the regulation of cardiac resistance to ischemic and reperfusion injuries].
Solenkova, N V⋅Maslov, L N and Downey, James M
Patologicheskaia fiziologiia i èksperimental'naia terapiia, (no. 2), pp. 28-31, 2006 Apr-Jun. | Journal Article
 
Atrial natriuretic peptide administered just prior to reperfusion limits infarction in rabbit hearts.
Yang, Xi-Ming⋅Philipp, Sebastian⋅Downey, James M and Cohen, Michael V
Basic research in cardiology, vol. 101, (no. 4), pp. 311-8, 2006/Jul. | Journal Article
 
Desferoxamine and ethyl-3,4-dihydroxybenzoate protect myocardium by activating NOS and generating mitochondrial ROS.
Philipp, Sebastian⋅Cui, Lin⋅Ludolph, Barbara⋅Kelm, Malte⋅Schulz, Rainer⋅Cohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 290, (no. 1), pp. H450-7, 2006/Jan. | Journal Article
 
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt
Solenkova, Nataliya V⋅Solodushko, Viktoriya⋅Cohen, Michael and Downey, James M
American Journal of Physiology, vol. 59, (no. 1), pp. H441-H449, Jan 2006. | Journal Article
 
Endogenous adenosine protects preconditioned heart during early minutes of reperfusion by activating Akt.
Solenkova, Nataliya V⋅Solodushko, Viktoriya⋅Cohen, Michael V and Downey, James M
American journal of physiology. Heart and circulatory physiology, vol. 290, (no. 1), pp. H441-9, 2006/Jan. | Journal Article
 
Localizing extracellular signal-regulated kinase (ERK) in pharmacological preconditioning's trigger pathway.
Philipp, Sebastian⋅Critz, Stuart D⋅Cui, Lin⋅Solodushko, Viktoriya⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 101, (no. 2), pp. 159-67, 2006/Mar. | Journal Article
 
NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase.
Förster, Karina⋅Paul, Ina⋅Solenkova, Natalia⋅Staudt, Alexander⋅Cohen, Michael V⋅Downey, James M⋅Felix, Stephan B and Krieg, Thomas
Basic research in cardiology, vol. 101, (no. 4), pp. 319-26, 2006/Jul. | Journal Article
 
Nitric oxide is a preconditioning mimetic and cardioprotectant and is the basis of many available infarct-sparing strategies.
Cohen, Michael V⋅Yang, Xi-Ming and Downey, James M
Cardiovascular research, vol. 70, (no. 2), pp. 231-9, 2006/May/1. | Journal Article
 
Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.
Philipp, Sebastian⋅Yang, Xi-Ming⋅Cui, Lin⋅Davis, Amanda M⋅Downey, James M and Cohen, Michael V
Cardiovascular research, vol. 70, (no. 2), pp. 308-14, 2006/May/1. | Journal Article
 
Protection from post-conditioning depends on the number of short ischemic insults in anesthetized pigs.
Iliodromitis, Efstathios K⋅Georgiadis, Michael⋅Cohen, Michael V⋅Downey, James M⋅Bofilis, Elias and Kremastinos, Dimitrios T
Basic research in cardiology, vol. 101, (no. 6), pp. 502-7, 2006/Nov. | Journal Article