267 Publications (Page 1 of 11)
2018
Caspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function.
Audia, Jonathon P.⋅Audia, Jonathon P⋅Yang, Xi-Ming⋅Yang, Xi-Ming⋅Crockett, Edward S⋅Crockett, Edward S.⋅Housley, Nicole⋅Housley, Nicole⋅Haq, Ehtesham Ul⋅Haq, Ehtesham Ul⋅O'Donnell, Kristen⋅O’Donnell, Kristen⋅Cohen, Michael V.⋅Cohen, Michael V⋅Downey, James M.⋅Downey, James M⋅Alvarez, Diego F and Alvarez, Diego F.
Basic research in cardiology, vol. 113, (no. 5), pp. 32, July 10, 2018. | Journal Article
 
Circulating blood cells and extracellular vesicles in acute cardioprotection.
Davidson, Sean M⋅Davidson, Sean M⋅Andreadou, Ioanna⋅Andreadou, Ioanna⋅Barile, Lucio⋅Barile, Lucio⋅Birnbaum, Yochai⋅Birnbaum, Yochai⋅Cabrera-Fuentes, Hector A⋅Cabrera-Fuentes, Hector A⋅Cohen, Michael V⋅Cohen, Michael V⋅Downey, James M⋅Downey, James M⋅Girao, Henrique⋅Girao, Henrique⋅Pagliaro, Pasquale⋅Pagliaro, Pasquale⋅Penna, Claudia⋅Penna, Claudia⋅Pernow, John⋅Pernow, John⋅Preissner, Klaus T⋅Preissner, Klaus T⋅Ferdinandy, Peter and Ferdinandy, Peter
Cardiovascular research, December 24, 2018. | Journal Article
 
Innate immunity as a target for acute cardioprotection.
Zuurbier, Coert J⋅Abbate, Antonio⋅Cabrera-Fuentes, Hector A⋅Cohen, Michael V⋅Collino, Massimo⋅De Kleijn, Dominique P V⋅Downey, James M⋅Pagliaro, Pasquale⋅Preissner, Klaus T⋅Takahashi, Masafumi and Davidson, Sean M
Cardiovascular research, December 21, 2018. | Journal Article
 
Reactive Oxygen Species As Intracellular Signaling Molecules In The Cardiovascular System.
Krylatov, Andrey V⋅Maslov, Leonid N⋅Voronkov, Nikita S⋅Boshchenko, Alla A⋅Popov, Sergey V⋅Gomez, Ludovic⋅Wang, Hongxin⋅Jaggi, Amteshwar S and Downey, James M
Current cardiology reviews, July 2, 2018. | Journal Article
2015
Cardioprotective Properties of the Platelet P2Y12 Receptor Inhibitor, Cangrelor: Protective in Diabetics and Reliant Upon the Presence of Blood.
Bell, R M⋅Sivaraman, V⋅Kunuthur, S P⋅Cohen, M V⋅Downey, J M and Yellon, D M
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, vol. 29, (no. 5), pp. 415-418, 2015. | Journal Article
 
Mitochondrially targeted Endonuclease III has a powerful anti-infarct effect in an in vivo rat model of myocardial ischemia/reperfusion
Yang, Xi-ming⋅Cui, Lin⋅White, James⋅Kuck, Jamie⋅Ruchko, Mykhaylo⋅Wilson, Glenn⋅Alexeyev, Mikhail⋅Gillespie, Mark⋅Downey, James and Cohen, Michael
Basic Research in Cardiology, vol. 110, (no. 2), pp. 1-13, Mar 2015. | Journal Article
 
Signalling pathways and mechanisms of protection in pre- and postconditioning: historical perspective and lessons for the future.
Cohen, Michael V and Downey, James M
British journal of pharmacology, vol. 172, (no. 8), pp. 1913-1932, April 2015. | Journal Article
 
Status of P2Y12 treatment must be considered in evaluation of myocardial ischaemia/reperfusion injury.
Cohen, Michael V⋅Cohen, Michael V⋅Downey, James M and Downey, James M
(pp. 8). April 1, 2015
 
What is Wrong With Cardiac Conditioning? We May be Shooting at Moving Targets.
Iliodromitis, Efstathios K⋅Cohen, Michael V⋅Dagres, Nikolaos⋅Andreadou, Ioanna⋅Kremastinos, Dimitrios Th and Downey, James M
Journal of cardiovascular pharmacology and therapeutics, vol. 20, (no. 4), pp. 357-369, July 2015. | Journal Article
2014
Combined cardioprotectant and antithrombotic actions of platelet P2Y12 receptor antagonists in acute coronary syndrome: just what the doctor ordered.
Cohen, Michael V⋅Cohen, Michael V⋅Downey, James M and Downey, James M
Journal of cardiovascular pharmacology and therapeutics, vol. 19, (no. 2), pp. 179-190, March 2014. | Journal Article
2013
Platelet P2Y₁₂ blockers confer direct postconditioning-like protection in reperfused rabbit hearts.
Yang, Xi-Ming⋅Yang, Xi-Ming⋅Liu, Yanping⋅Liu, Yanping⋅Cui, Lin⋅Cui, Lin⋅Yang, Xiulan⋅Yang, Xiulan⋅Liu, Yongge⋅Liu, Yongge⋅Tandon, Narendra⋅Tandon, Narendra⋅Kambayashi, Junichi⋅Kambayashi, Junichi⋅Downey, James M⋅Downey, James M⋅Cohen, Michael V and Cohen, Michael V
Journal of cardiovascular pharmacology and therapeutics, vol. 18, (no. 3), pp. 251-62, 2013/May. | Journal Article
 
Triple therapy greatly increases myocardial salvage during ischemia/reperfusion in the in situ rat heart.
Yang, Xi-Ming⋅Yang, Xi-Ming⋅Cui, Lin⋅Cui, Lin⋅Alhammouri, Ahmad⋅Alhammouri, Ahmad⋅Downey, James M.⋅Downey, James M⋅Cohen, Michael V and Cohen, Michael V.
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, vol. 27, (no. 5), pp. 403-12, 2013/Oct. | Journal Article
 
Two classes of anti-platelet drugs reduce anatomical infarct size in monkey hearts.
Yang, Xi-Ming⋅Liu, Yanping⋅Cui, Lin⋅Yang, Xiulan⋅Liu, Yongge⋅Tandon, Narendra⋅Kambayashi, Junichi⋅Downey, James M and Cohen, Michael V
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy, vol. 27, (no. 2), pp. 109-15, 2013/Apr. | Journal Article
2012
Adenosine and opioid receptors do not trigger the cardioprotective effect of mild hypothermia.
Darbera, Lys⋅Chenoune, Mourad⋅Lidouren, Fanny⋅Ghaleh, Bijan⋅Cohen, Michael V⋅Downey, James M⋅Berdeaux, Alain and Tissier, Renaud
Journal of cardiovascular pharmacology and therapeutics, vol. 17, (no. 2), pp. 173-80, 2012/Jun. | Journal Article
 
All preconditioning-related G protein-coupled receptors can be demonstrated in the rabbit cardiomyocyte.
Xin, Wenkuan⋅Yang, Xiulan⋅Rich, Thomas C⋅Krieg, Thomas⋅Barrington, Robert⋅Cohen, Michael V and Downey, James M
Journal of cardiovascular pharmacology and therapeutics, vol. 17, (no. 2), pp. 190-8, 2012/Jun. | Journal Article
 
Myocardial protection with mild hypothermia.
Tissier, Renaud⋅Ghaleh, Bijan⋅Cohen, Michael V⋅Downey, James M and Berdeaux, Alain
Cardiovascular research, vol. 94, (no. 2), pp. 217-25, 2012/May/1. | Journal Article
2011
A2B adenosine receptors inhibit superoxide production from mitochondrial complex I in rabbit cardiomyocytes via a mechanism sensitive to Pertussis toxin
Yang, Xiulan⋅Xin, Wenkuan⋅Yang, Xi-Ming⋅Kuno, Atsushi⋅Rich, Thomas C⋅Cohen, Michael and Downey, James M
British Journal of Pharmacology, vol. 163, (no. 5), pp. 995-1006, 2011. | Journal Article
 
Cardioprotection by mild hypothermia during ischemia involves preservation of ERK activity.
Yang, Xiulan⋅Liu, Yanping⋅Yang, Xi-Ming⋅Hu, Fangdi⋅Cui, Lin⋅Swingle, Mark R⋅Honkanen, Richard E⋅Soltani, Peyman⋅Tissier, Renaud⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 106, (no. 3), pp. 421-30, 2011/May. | Journal Article
 
Does mild hypothermia protect against reperfusion injury? The debate continues.
Tissier, Renaud⋅Cohen, Michael V and Downey, James M
Basic research in cardiology, vol. 106, (no. 5), pp. 691-5, 2011/Sep. | Journal Article
 
Evidence for an intracellular localization of the adenosine A2B receptor in rat cardiomyocytes.
Grube, Karina⋅Rüdebusch, Julia⋅Xu, Zhelong⋅Böckenholt, Thomas⋅Methner, Carmen⋅Müller, Tobias⋅Cuello, Friederike⋅Zimmermann, Katrin⋅Yang, Xiulan⋅Felix, Stephan B⋅Cohen, Michael V⋅Downey, James M and Krieg, Thomas
Basic research in cardiology, vol. 106, (no. 3), pp. 385-96, 2011/May. | Journal Article
 
Evidence for an intracellular localization of the adenosine A^sub 2B^ receptor in rat cardiomyocytes
Grube, Karina⋅Rüdebusch, Julia⋅Xu, Zhelong⋅Böckenholt, Thomas⋅Methner, Carmen⋅Müller, Tobias⋅Cuello, Friederike⋅Zimmermann, Katrin⋅Yang, Xiulan⋅Felix, Stephan⋅Cohen, Michael⋅Downey, James and Krieg, Thomas
Basic Research in Cardiology, vol. 106, (no. 3), pp. 385-96, May 2011. | Journal Article
 
Ischemic postconditioning: from receptor to end-effector.
Cohen, Michael V and Downey, James M
Antioxidants & redox signaling, vol. 14, (no. 5), pp. 821-31, 2011/Mar/1. | Journal Article
 
New horizons in cardioprotection: recommendations from the 2010 National Heart, Lung, and Blood Institute Workshop.
Schwartz Longacre, Lisa⋅Kloner, Robert A⋅Arai, Andrew E⋅Baines, Christopher Philip⋅Bolli, Roberto⋅Braunwald, Eugene⋅Downey, James⋅Gibbons, Raymond J⋅Gottlieb, Roberta A⋅Heusch, Gerd⋅Jennings, Robert B⋅Lefer, David J⋅Mentzer, Robert M⋅Murphy, Elizabeth⋅Ovize, Michel⋅Ping, Peipei⋅Przyklenk, Karin⋅Sack, Michael N⋅Vander Heide, Richard S⋅Vinten-Johansen, Jakob and Yellon, Derek
Circulation, vol. 124, (no. 10), pp. 1172-9, 2011/Sep/6. | Journal Article
2010
A(2b) adenosine receptors can change their spots.
Cohen, Michael V⋅Yang, Xiulan and Downey, James M
British journal of pharmacology, vol. 159, (no. 8), pp. 1595-7, 2010/Apr. | Journal Article
 
AMP579 is revealed to be a potent A2b-adenosine receptor agonist in human 293 cells and rabbit hearts.
Liu, Yanping⋅Yang, Xiulan⋅Yang, Xi-Ming⋅Walker, Sheree⋅Förster, Karina⋅Cohen, Michael V⋅Krieg, Thomas and Downey, James M
Basic research in cardiology, vol. 105, (no. 1), pp. 129-37, 2010/Jan. | Journal Article