87 Publications (Page 3 of 4)
2014
Targeting DNA repair pathways for cancer treatment: what's new?
Kelley, Mark R⋅Kelley, Mark R⋅Logsdon, Derek⋅Logsdon, Derek⋅Fishel, Melissa L and Fishel, Melissa L
Future Oncology, vol. 10, (no. 7), pp. 1237, 2014-May-01. | Journal Article
2013
991 APE1/REF-1 REGULATES SURVIVIN-MEDIATED DRUG RESISTANCE IN PROSTATE CANCER CELLS
McIlwain, David⋅McIlwain, David⋅McIlwain, David⋅Fishel, Melissa⋅Fishel, Melissa⋅Fishel, Melissa⋅Wang, Liang⋅Wang, Liang⋅Wang, Liang⋅Snider, Brandy⋅Snider, Brandy⋅Snider, Brandy⋅Zhang, Jian-Ting⋅Zhang, Jian-Ting⋅Zhang, Jian-Ting⋅Kelley, Mark⋅Kelley, Mark⋅Kelley, Mark⋅Jerde, Travis⋅Jerde, Travis and Jerde, Travis
Journal of Urology, The, vol. 189, (no. 4), pp. e407, 2013. | Journal Article
 
DNA Base Excision Repair Therapeutics
Fishel, Melissa⋅Vascotto, Carlo and Kelley, Mark
(pp. 233–287). CRC Press
2012
APE1/Ref-1 Regulates STAT3 Transcriptional Activity and APE1/Ref-1–STAT3 Dual-Targeting Effectively Inhibits Pancreatic Cancer Cell Survival
Cardoso, Angelo A⋅Cardoso, Angelo A⋅Jiang, Yanlin⋅Jiang, Yanlin⋅Luo, Meihua⋅Luo, Meihua⋅Reed, April M⋅Reed, April M⋅Shahda, Safi⋅Shahda, Safi⋅He, Ying⋅He, Ying⋅Maitra, Anirban⋅Maitra, Anirban⋅Kelley, Mark⋅Kelley, Mark R⋅Fishel, Melissa L and Fishel, Melissa L
PloS one, vol. 7, (no. 10), pp. e47462, 2012-00-00. | Journal Article
 
APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1
Kelley, Mark⋅Kelley, Mark R⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Fishel, Melissa L and Fishel, Melissa L
Current molecular pharmacology, vol. 5, (no. 1), pp. 53, 2012-Jan. | Journal Article
 
APE1/Ref-1Role in Redox Signaling: Translational Applications of Targeting the Redox Function of the DNA Repair/Redox Protein APE1/Ref-1
Kelley, Mark⋅Kelley, Mark⋅Kelley, Mark⋅Georgiadis, Millie⋅Georgiadis, Millie⋅Georgiadis, Millie⋅Fishel, Melissa⋅Fishel, Melissa and Fishel, Melissa
Current Molecular Pharmacology, vol. 5, (no. 1), pp. 53, 2012-January. | Journal Article
 
Blockade of Base Excision Repair
Vascotto, C.⋅Vascotto, Carlo⋅Fishel, M.L. and Fishel, Melissa L.
(pp. 29–53). Elsevier
 
DNA repair and cancer therapeutics
Kelley, M.R. and Fishel, M.L.
2012
 
DNA repair and cancer therapeutics
Kelley, M.R. and Fishel, M.L.
(pp. 566-579)
2011
Impact of APE1/Ref-1 Redox Inhibition on Pancreatic Tumor Growth
Fishel, Melissa L⋅Fishel, Melissa L⋅Jiang, Yanlin⋅Jiang, Yanlin⋅Rajeshkumar, N V⋅Rajeshkumar, N V⋅Scandura, Glenda⋅Scandura, Glenda⋅Sinn, Anthony L⋅Sinn, Anthony L⋅He, Ying⋅He, Ying⋅Shen, Changyu⋅Shen, Changyu⋅Jones, David R⋅Jones, David R⋅Pollok, Karen E⋅Pollok, Karen E⋅Ivan, Mircea⋅Ivan, Mircea⋅Maitra, Anirban⋅Maitra, Anirban⋅Kelley, Mark R and Kelley, Mark
Molecular cancer therapeutics, vol. 10, (no. 9), pp. 1708, 2011-Sep. | Journal Article
2010
Abstract 1963: Novel small molecule inhibitor of the endonuclease function of the APE1 DNA repair and redox signaling enzyme blocks proliferation and reduces viability of glioblastoma cells
Bapat, Aditi⋅Bapat, Aditi⋅Bapat, Aditi⋅Bapat, Aditi⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Glass, LaTeca S⋅Luo, Meihua⋅Luo, Meihua⋅Luo, Meihua⋅Luo, Meihua⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Reed, April⋅Reed, April⋅Reed, April⋅Reed, April⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Long, Eric C⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R⋅Kelley, Mark R⋅Kelley, Mark R and Kelley, Mark R
Cancer Research, vol. 70, (no. 8 Supplement), pp. 1963, 2010-04-15. | Journal Article
 
DNA Repair and Redox Signaling
Kelley, Mark R.⋅Georgiadis, Millie M. and Fishel, Melissa L.
(pp. 133–168). Springer New York
 
Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis
Fishel, Melissa L⋅Fishel, Melissa⋅Colvin, E.⋅Colvin, E S⋅Luo, Meihua⋅Luo, Meihua⋅Kelley, Mark⋅Kelley, Mark⋅Robertson, Kent and Robertson, Kent A
Experimental Hematology, vol. 38, (no. 12), pp. 1188, 2010. | Journal Article
 
Novel Small-Molecule Inhibitor of Apurinic/Apyrimidinic Endonuclease 1 Blocks Proliferation and Reduces Viability of Glioblastoma Cells
Bapat, Aditi⋅Bapat, Aditi⋅Glass, Lateca S⋅Glass, Lateca S⋅Luo, Meihua⋅Luo, Meihua⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Long, Eric C⋅Long, Eric C⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R and Kelley, Mark
The Journal of pharmacology and experimental therapeutics, vol. 334, (no. 3), pp. 998, 2010-Sep-01. | Journal Article
 
Reduced Expression of DNA Repair and Redox Signaling Protein APE1/Ref-1 Impairs Human Pancreatic Cancer Cell Survival, Proliferation, and Cell Cycle Progression
Jiang, Yanlin⋅Jiang, Yanlin⋅Jiang, Yanlin⋅Zhou, Shaoyu⋅Zhou, Shaoyu⋅Zhou, Shaoyu⋅Sandusky, George E⋅Sandusky, George E⋅Sandusky, George E⋅Kelley, Mark⋅Kelley, Mark R⋅Kelley, Mark R⋅Fishel, Melissa L⋅Fishel, Melissa L and Fishel, Melissa L
Cancer Investigation, vol. 28, (no. 9), pp. 895, 20101000. | Journal Article
2009
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity
Tate, Courtney M⋅Tate, Courtney M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Holleran, Julianne L⋅Holleran, Julianne L⋅Egorin, Merrill J⋅Egorin, Merrill J⋅Skalnik, David G and Skalnik, David G
DNA Repair, vol. 8, (no. 12), pp. 1423, 2009. | Journal Article
 
Going Ape as an Approach to Cancer Therapeutics
Bapat, Aditi⋅Bapat, Aditi⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark and Kelley, Mark R
Antioxidants & redox signaling, vol. 11, (no. 3), pp. 667, 2009-Mar. | Journal Article
 
Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: Use of APE1 small molecule inhibitors to delineate APE1 functions
Jiang, Yanlin⋅Jiang, Y.⋅Guo, C.⋅Guo, Chunlu⋅Fishel, Melissa L⋅Fishel, ML⋅Wang, ZY⋅Wang, Zheng-Yu⋅Vasko, Michael R⋅Vasko, Michael R⋅Kelley, Mark R and Kelley, Mark R
DNA Repair, vol. 8, (no. 11), pp. 1282, 2009-11-02. | Journal Article
 
Small-molecule inhibitors of proteins involved in base excision repair potentiate the anti-tumorigenic effect of existing chemotherapeutics and irradiation
Reed, April M⋅Reed, April M⋅Fishel, Melissa L⋅Fishel, Melissa L⋅Kelley, Mark R and Kelley, Mark
Future Oncology, vol. 5, (no. 5), pp. 726, 2009-June-01. | Journal Article
2008
DNA Repair Proteins as Molecular Targets for Cancer Therapeutics
Kelley, Mark R⋅Kelley, Mark⋅Fishel, Melissa L and Fishel, Melissa
Anti-Cancer Agents in Medicinal Chemistry, vol. 8, (no. 4), pp. 425, 2008-May. | Journal Article
 
Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress
Rabik, Cara⋅Rabik, Cara A⋅Rabik, Cara⋅Fishel, Melissa⋅Fishel, Melissa L⋅Fishel, Melissa⋅Holleran, Julianne⋅Holleran, Julianne⋅Holleran, Julianne L⋅Kasza, Kristen⋅Kasza, Kristen⋅Kasza, Kristen⋅Kelley, Mark⋅Kelley, Mark R⋅Kelley, Mark⋅Egorin, Merrill⋅Egorin, Merrill⋅Egorin, Merrill J⋅Dolan, M.⋅Dolan, M. and Dolan, M. E
Journal of Pharmacology and Experimental Therapeutics, vol. 327, (no. 2), pp. 452, 20081101. | Journal Article
 
Knockdown of the DNA repair and redox signaling protein Ape1/Ref-1 blocks ovarian cancer cell and tumor growth
Fishel, Melissa L⋅Fishel, Melissa L⋅Fishel, ML⋅He, Ying⋅He, Ying⋅He, Y.⋅Reed, April M⋅Reed, April M⋅Reed, AM⋅Chin-Sinex, Helen⋅Chin-Sinex, H.⋅Chin-Sinex, Helen⋅Hutchins, Gary D⋅Hutchins, Gd⋅Hutchins, Gary D⋅Mendonca, Marc S⋅Mendonca, MS⋅Mendonca, Marc S⋅Kelley, Mark R⋅Kelley, Mark R and Kelley, Mark R
DNA Repair, vol. 7, (no. 2), pp. 186, 2008. | Journal Article
 
Role of the Multifunctional DNA Repair and Redox Signaling Protein Ape1/Ref-1 in Cancer and Endothelial Cells: Small-Molecule Inhibition of the Redox Function of Ape1
Luo, M.⋅Luo, Meihua⋅Delaplane, Sarah⋅Delaplane, S.⋅Jiang, Aihua⋅Jiang, A.⋅Reed, April⋅Reed, A.⋅He, Y.⋅He, Ying⋅Fishel, Melissa⋅Fishel, M.⋅Nyland, 2nd, Rodney L⋅Nyland, RL I⋅Borch, Richard F⋅Borch, Rich F⋅Qiao, X.⋅Qiao, Xiaoxi⋅Georgiadis, Millie M⋅Georgiadis, Millie M⋅Kelley, Mark R and Kelley, Mark R
Antioxidants & redox signaling, vol. 10, (no. 11), pp. 1867, 2008-Nov. | Journal Article
2007
DNA repair in neurons: so if they don't divide what's to repair?
Fishel, Melissa L⋅Fishel, Melissa L⋅Vasko, Michael R⋅Vasko, Michael R⋅Kelley, Mark and Kelley, Mark R
Mutation research, vol. 614, (no. 1-2), pp. 24, 2007-Jan-03. | Journal Article
 
Manipulation of Base Excision Repair to Sensitize Ovarian Cancer Cells to Alkylating Agent Temozolomide
Fishel, Melissa L⋅Fishel, Melissa⋅He, Ying⋅He, Ying⋅Smith, Martin L⋅Smith, Martin⋅Kelley, Mark R and Kelley, Mark
Clinical Cancer Research, vol. 13, (no. 1), pp. 267, 20070101. | Journal Article