217 Publications (Page 2 of 9)
2019
Insulin regulates POMC neuronal plasticity to control glucose metabolism
Dodd, Garron T⋅Michael, Natalie J⋅Lee-Young, Robert S⋅Mangiafico, Salvatore P⋅Pryor, Jack T⋅Munder, Astrid C⋅Simonds, Stephanie E⋅Brüning, Jens C⋅Zhang, Zhong Yin⋅Cowley, Michael A⋅Andrikopoulos, Sofianos⋅Hovarth, Tamas L⋅Spanswick, David and Tiganis, Tony
Obesity Research & Clinical Practice, vol. 13, (no. 3), pp. 257, 2019-05-00. | Journal Article
 
Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin
Sima, Livia Elena⋅Sima, Livia Elena⋅Sima, Livia Elena⋅Yakubov, Bakhtiyor⋅Yakubov, Bakhtiyor⋅Yakubov, Bakhtiyor⋅Zhang, Sheng⋅Zhang, Sheng⋅Zhang, Sheng⋅Condello, Salvatore⋅Condello, Salvatore⋅Condello, Salvatore⋅Grigorescu, Arabela A⋅Grigorescu, Arabela A⋅Grigorescu, Arabela A⋅Nwani, Nkechiyere G⋅Nwani, Nkechiyere G⋅Nwani, Nkechiyere G⋅Chen, Lan⋅Chen, Lan⋅Chen, Lan⋅Schiltz, Gary E⋅Schiltz, Gary E⋅Schiltz, Gary E⋅Arvanitis, Constandina⋅Arvanitis, Constandina⋅Arvanitis, Constandina⋅Zhang, Zhong-Yin⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Matei, Daniela⋅Matei, Daniela and Matei, Daniela
Molecular cancer therapeutics, vol. 18, (no. 6), pp. 1068, 2019-06-00. | Journal Article
 
Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation
Kano, Yoshihito⋅Gebregiworgis, Teklab⋅Teklab, Gebregiworgis⋅Marshall, Christopher B⋅Marshall, Christopher B⋅Radulovich, Nikolina⋅Poon, Betty P K⋅St-Germain, Jonathan⋅St-Germain, Jonathan⋅Cook, Jonathan D⋅Cook, Jonathan D⋅Valencia-Sama, Ivette⋅Grant, Benjamin M M⋅Herrera, Silvia G⋅Herrera, Silvia Gabriela⋅Miao, Jinmin⋅Raught, Brian⋅Raught, Brian⋅Irwin, Meredith S⋅Irwin, Meredith S⋅Lee, Jeffrey E⋅Lee, Jeffrey E⋅Yeh, Jen J⋅Yeh, Jen Jen⋅Zhang, Zhong Yin⋅Zhong-Yin, Zhang⋅Tsao, Ming-Sound⋅⋅Ikura, Mitsuhiko⋅Ohh, Michael and Ohh, Michael
Nature communications, vol. 10, (no. 1), pp. 224, 2019-01-15. | Journal Article
2018
Development and Characterization of an Endotoxemia Model in Zebra Fish.
Hsu, Alan Y⋅Hsu, Alan Y⋅Gurol, Theodore⋅Gurol, Theodore⋅Sobreira, Tiago J P⋅Sobreira, Tiago J P⋅Zhang, Sheng⋅Zhang, Sheng⋅Moore, Natalie⋅Moore, Natalie⋅Cai, Chufan⋅Cai, Chufan⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Deng, Qing and Deng, Qing
Frontiers in immunology, vol. 9, pp. 607, 2018. | Journal Article
 
Insulin regulates POMC neuronal plasticity to control glucose metabolism
Dodd, G.T.⋅Dodd, Garron T⋅Dodd, G.T.⋅GT, Dodd⋅Dodd, Garron T⋅NJ, Michael⋅Michael, Natalie J⋅Michael, Natalie J⋅Michael, N.J.⋅Michael, N.J.⋅Lee-Young, Robert S⋅Lee-Young, R.S.⋅RS, Lee-Young⋅Lee-Young, R.S.⋅Lee-Young, Robert S⋅Mangiafico, S.P.⋅Mangiafico, S.P.⋅Mangiafico, Salvatore P⋅Mangiafico, Salvatore P⋅SP, Mangiafico⋅Pryor, Jack T⋅Pryor, J.T.⋅JT, Pryor⋅Pryor, J.T.⋅Pryor, Jack T⋅AC, Munder⋅Munder, A.C.⋅Munder, Astrid C⋅Munder, A.C.⋅Munder, Astrid C⋅SE, Simonds⋅Simonds, Stephanie E⋅Simonds, S.E.⋅Simonds, S.E.⋅Simonds, Stephanie E⋅Brüning, J.C.⋅Brüning, Jens Claus⋅Brüning, Jens Claus⋅Brüning, J.C.⋅JC, Brüning⋅ZY, Zhang⋅Zhang, Zhong-Yin⋅Zhang, Z.-Y.⋅Zhang, Z.-Y.⋅Zhang, Zhong Yin⋅MA, Cowley⋅Cowley, Michael A⋅Cowley, M.A.⋅Cowley, Michael A⋅Cowley, M.A.⋅S, Andrikopoulos⋅Andrikopoulos, Sofianos⋅Andrikopoulos, S.⋅Andrikopoulos, Sofianos⋅Andrikopoulos, S.⋅Horvath, T.L.⋅Horvath, T.L.⋅Horvath, Tamas L⋅Horvath, Tamas L⋅TL, Horvath⋅Spanswick, David⋅Spanswick, D.⋅Spanswick, D.⋅T, Tiganis⋅Spanswick, David⋅Tiganis, T.⋅Tiganis, Tony⋅Tiganis, T. and Tiganis, Tony
eLife, vol. 7, 2018-09-19. | Journal Article
 
Targeting ovarian cancer and endothelium with an allosteric PTP4A3 phosphatase inhibitor
McQueeney, Kelley E⋅McQueeney, Kelley E⋅Salamoun, Joseph M⋅Salamoun, Joseph M⋅Burnett, James C⋅Burnett, James C⋅Barabutis, Nektarios⋅Barabutis, Nektarios⋅Pekic, Paula⋅Pekic, Paula⋅Lewandowski, Sophie L⋅Lewandowski, Sophie L⋅Llaneza, Danielle C⋅Llaneza, Danielle C⋅Cornelison, Robert⋅Cornelison, Robert⋅Bai, Yunpeng⋅Bai, Yunpeng⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Catravas, John D⋅Catravas, John D⋅Landen, Charles N⋅Landen, Charles N⋅Wipf, Peter⋅Wipf, Peter⋅Lazo, John S⋅Lazo, John S⋅Sharlow, Elizabeth R and Sharlow, Elizabeth R
Oncotarget, vol. 9, (no. 9), pp. 8240, 2018-Feb-02. | Journal Article
 
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis
Zehender, Ariella⋅Huang, Jingang⋅Györfi, Andrea-Hermina⋅Matei, Alexandru-Emil⋅Trinh-Minh, Thuong⋅Xu, Xiaohan⋅Li, Yi-Nan⋅Chen, Chih-Wei⋅Lin, Jianping⋅Dees, Clara⋅Beyer, Christian⋅Gelse, Kolja⋅Zhang, Zhong Yin⋅Bergmann, Christina⋅Ramming, Andreas⋅Birchmeier, Walter⋅Distler, Oliver⋅Schett, Georg and Distler, Jörg H. W
Nature Communications, vol. 9, (no. 1), pp. 17, 2018-12-00. | Journal Article
 
Total Synthesis, Biological Evaluation, and Target Identification of Rare Abies Sesquiterpenoids
Davis, Dexter C⋅Davis, Dexter C⋅Hoch, Dominic G⋅Hoch, Dominic G⋅Wu, Li⋅Wu, Li⋅Abegg, Daniel⋅Abegg, Daniel⋅Martin, Brandon S⋅Martin, Brandon S⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Adibekian, Alexander⋅Adibekian, Alexander⋅Dai, Mingji and Dai, Mingji
Journal of the American Chemical Society, vol. 140, (no. 50), pp. 17473, 20181219. | Journal Article
2017
Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers.
Prabhu, Lakshmi⋅Prabhu, Lakshmi⋅Wei, Han⋅Wei, Han⋅Chen, Lan⋅Chen, Lan⋅Demir, Özlem⋅Demir, Özlem⋅Sandusky, George⋅Sandusky, George⋅Sun, Emily⋅Sun, Emily⋅Wang, John⋅Wang, John⋅Mo, Jessica⋅Mo, Jessica⋅Zeng, Lifan⋅Zeng, Lifan⋅Fishel, Melissa⋅Fishel, Melissa⋅Safa, Ahmad⋅Safa, Ahmad⋅Amaro, Rommie⋅Amaro, Rommie⋅Korc, Murray⋅Korc, Murray⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Lu, Tao and Lu, Tao
Oncotarget, vol. 8, (no. 25), pp. 39963-39977, June 20, 2017. | Journal Article
 
Covalent inhibition of protein tyrosine phosphatases.
Ruddraraju, Kasi Viswanatharaju and Zhang, Zhong Yin
Molecular bioSystems, May 23, 2017. | Journal Article
 
Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases
Zhang, Zhong Yin
Accounts of Chemical Research, vol. 50, (no. 1), pp. 129, 20170117. | Journal Article
 
Phospho-Regulation of Soma-to-Axon Transcytosis of Neurotrophin Receptors.
Yamashita, Naoya⋅Joshi, Rajshri⋅Zhang, Sheng⋅Zhang, Zhong Yin and Kuruvilla, Rejji
Developmental cell, September 9, 2017. | Journal Article
 
Regulatory Mechanisms and Novel Therapeutic Targeting Strategies for Protein Tyrosine Phosphatases.
Yu, Zhi-Hong and Zhang, Zhong Yin
Chemical reviews, May 25, 2017. | Journal Article
 
Therapeutic targeting of oncogenic tyrosine phosphatases.
Frankson, Rochelle⋅Yu, Zhi-Hong⋅Bai, Yunpeng⋅Li, Qinglin⋅Zhang, Ruo-Yu and Zhang, Zhong Yin
Cancer research, August 30, 2017. | Journal Article
 
The tumor promoter-activated protein kinase Cs are a system for regulating filopodia.
Heckman, Carol A⋅Pandey, Pratima⋅Cayer, Marilyn L⋅Biswas, Tania⋅Zhang, Zhong Yin and Boudreau, Nancy S
Cytoskeleton (Hoboken, N.J.), May 8, 2017. | Journal Article
2016
Abnormal PTPN11 enhancer methylation promotes rheumatoid arthritis fibroblast-like synoviocyte aggressiveness and joint inflammation.
Maeshima, Keisuke⋅Maeshima, Keisuke⋅Stanford, Stephanie M⋅Stanford, Stephanie M⋅Hammaker, Deepa⋅Hammaker, Deepa⋅Sacchetti, Cristiano⋅Sacchetti, Cristiano⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Ai, Rizi⋅Ai, Rizi⋅Zhang, Vida⋅Zhang, Vida⋅Boyle, David L⋅Boyle, David L⋅Aleman Muench, German R⋅Aleman Muench, German R⋅Feng, Gen-Sheng⋅Feng, Gen-Sheng⋅Whitaker, John W⋅Whitaker, John W⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Wang, Wei⋅Wang, Wei⋅Bottini, Nunzio⋅Bottini, Nunzio⋅Firestein, Gary S and Firestein, Gary S
JCI insight, vol. 1, (no. 7), May 19, 2016. | Journal Article
 
A novel role for protein tyrosine phosphatase 1B as a positive regulator of neuroinflammation.
Song, Gyun Jee⋅Jung, Myungsu⋅Kim, Jong-Heon⋅Park, Hana⋅Rahman, Md Habibur⋅Zhang, Sheng⋅Zhang, Zhong Yin⋅Park, Dong Ho⋅Kook, Hyun⋅Lee, In-Kyu and Suk, Kyoungho
Journal of neuroinflammation, vol. 13, (no. 1), pp. 86, April 19, 2016. | Journal Article
 
Comparative Analysis of Protein Tyrosine Phosphatases Regulating Microglial Activation.
Song, Gyun Jee⋅Kim, Jaehong⋅Kim, Jong-Heon⋅Song, Seungeun⋅Park, Hana⋅Zhang, Zhong Yin and Suk, Kyoungho
Experimental neurobiology, vol. 25, (no. 5), pp. 252-261, October 2016. | Journal Article
 
Design, synthesis and evaluation of novel 19F magnetic resonance sensitive protein tyrosine phosphatase inhibitors
Li, Yu⋅Xia, Guiquan⋅Guo, Qi⋅Wu, Li⋅Chen, Shizhen⋅Yang, Zhigang⋅Wang, Wei⋅Zhang, Zhong Yin⋅Zhou, Xin and Jiang, Zhong-Xing
MedChemComm, vol. 7, (no. 8), pp. 1680, 2016-08-11. | Journal Article
 
Discovery and Evaluation of PRL Trimer Disruptors for Novel Anticancer Agents.
Bai, Yunpeng⋅Yu, Zhi-Hong and Zhang, Zhong Yin
Methods in molecular biology (Clifton, N.J.), vol. 1447, pp. 121-138, 2016. | Journal Article
 
Drugging the Undruggable: Therapeutic Potential of Targeting Protein Tyrosine Phosphatases.
Zhang, Zhong Yin
Accounts of chemical research, December 15, 2016. | Journal Article
 
Inhibition of Low Molecular Weight Protein Tyrosine Phosphatase by an Induced-Fit Mechanism.
He, Rongjun⋅Wang, Jifeng⋅Yu, Zhi-Hong⋅Zhang, Ruo-Yu⋅Liu, Sijiu⋅Wu, Li and Zhang, Zhong Yin
Journal of medicinal chemistry, October 3, 2016. | Journal Article
 
Inhibition of SHP2 ameliorates the pathogenesis of systemic lupus erythematosus
Wang, Jianxun⋅Wang, Jianxun⋅Mizui, Masayuki⋅Mizui, Masayuki⋅Zeng, Li-Fan⋅Zeng, Li-Fan⋅Bronson, Roderick⋅Bronson, Roderick⋅Finnell, Michele⋅Finnell, Michele⋅Terhorst, Cox⋅Terhorst, Cox⋅Kyttaris, Vasileios⋅Kyttaris, Vasileios C⋅Tsokos, George C⋅Tsokos, George⋅Zhang, Zhong-Yin⋅Zhang, Zhong Yin⋅Kontaridis, Maria and Kontaridis, Maria I
Journal of Clinical Investigation, vol. 126, (no. 6), pp. 2077-2092, Jun 2016. | Journal Article
 
Negative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.
Hamerman, Jessica A⋅Pottle, Jessica⋅Ni, Minjian⋅He, Yantao⋅Zhang, Zhong Yin and Buckner, Jane H
Immunological reviews, vol. 269, (no. 1), pp. 212-227, January 2016. | Journal Article
 
Novel Anticancer Agents Based on Targeting the Trimer Interface of the PRL Phosphatase.
Bai, Yunpeng⋅Yu, Zhi-Hong⋅Liu, Sijiu⋅Zhang, Lujuan⋅Zhang, Ruo-Yu⋅Zeng, Li-Fan⋅Zhang, Sheng and Zhang, Zhong Yin
Cancer research, vol. 76, (no. 16), pp. 4805-4815, August 15, 2016. | Journal Article