217 Publications (Page 9 of 9)
1996
Quiescent affinity inactivators of protein tyrosine phosphatases
Taylor, William PTaylor, W PTaylor, William PZhang, Zhong-YinZhang, Z. FZhang, Zhong YinWidlanski, Theodore SWidlanski, Theodore S and Widlanski, T S
Bioorganic & Medicinal Chemistry, vol. 4, (no. 9), pp. 1520, 1996. | Journal Article
 
Reactivity of Alcohols Toward the Phosphoenzyme Intermediate in the Protein-Tyrosine Phosphatase-Catalyzed Reaction:  Probing the Transition State of the Dephosphorylation Step
Zhao, YZhao, YuZhang, Zhong Yin and Zhang, Z. F
Biochemistry, vol. 35, (no. 36), pp. 11804, 19960910. | Journal Article
 
Small Molecule Interactions with Protein−Tyrosine Phosphatase PTP1B and Their Use in Inhibitor Design
Burke, Terrence RBurke, Terrence RYe, BYe, BinYan, XYan, XinjianWang, SWang, ShaomengJia, ZongchaoJia, ZongchaoChen, LChen, LiZhang, Zhong YinZhang, Z. FBarford, D and Barford, David
Biochemistry, vol. 35, (no. 50), pp. 15996, 19961217. | Journal Article
 
The Active Site Specificity of the Yersinia Protein-tyrosine Phosphatase
Dunn, D.Dunn, DerekChen, LiChen, LiLawrence, David SLawrence, DavidZhang, Zhong Yin and Zhang, Zhong Yin
Journal of Biological Chemistry, vol. 271, (no. 1), pp. 168, 19960105. | Journal Article
 
VHR and PTP1 Protein Phosphatases Exhibit Remarkably Different Active Site Specificities toward Low Molecular Weight Nonpeptidic Substrates
Chen, LChen, LiMontserat, JavierMontserat, JLawrence, D SLawrence, David SZhang, Z. F and Zhang, Zhong Yin
Biochemistry, vol. 35, (no. 29), pp. 9354, 19960723. | Journal Article
1995
Are Protein-tyrosine Phosphatases Specific for Phosphotyrosine?
Zhang, Zhong Yin and Zhang, Zhong Yin
Journal of Biological Chemistry, vol. 270, (no. 27), pp. 16052, 19950707. | Journal Article
 
Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif
Zhang, Z.-Y.Zhang, Zhong YinZhang, Z. FPalfey, B.A.Palfey, B APalfey, Bruce AWu, LiWu, L.Wu, LZhao, YuZhao, Y and Zhao, Y.
Biochemistry, vol. 34, (no. 50), pp. 16396, 19951201. | Journal Article
 
Kinetic and Mechanistic Characterization of a Mammalian Protein-tyrosine Phosphatase, PTP1
Zhang, Z. F and Zhang, Zhong Yin
The Journal of biological chemistry, vol. 270, (no. 19), pp. 11204, 1995-05-12. | Journal Article
 
Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction
Hengge, AlvanHengge, Alvan CSowa, GASowa, Gwendolyn AWu, LiWu, LiZhang, Zhong Yin and Zhang, Zhong Yin
Biochemistry (Easton), vol. 34, (no. 43), pp. 13987, 1995-10-31. | Journal Article
 
Synthesis and bioassay of a protein tyrosine phosphatase inhibitor, dephostatin
Yu, LibingMcGill, AndreaRamirez, JohnnyWang, Peng George and Zhang, Zhong Yin
Bioorganic & Medicinal Chemistry Letters, vol. 5, (no. 9), pp. 1006, 1995. | Journal Article
 
Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR
Zhang, Z. FZhang, Zhong YinWu, LWu, LiChen, L and Chen, Li
Biochemistry, vol. 34, (no. 49), pp. 16096, 19951201. | Journal Article
1994
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 Å and the complex with tungstate
Dixon, Jack EFauman, Eric BZhang, Zhong-YinSaper, Mark AStuckey, Jeanne AStuckey, Jeanne ASchubert, Heidi LSchubert, Heidi LFauman, Eric BZhang, Zhong YinDixon, Jack E and Saper, Mark A
Nature (London), vol. 370, (no. 6490), pp. 575, 1994-Aug-18. | Journal Article
 
Dissecting the Catalytic Mechanism of Protein-Tyrosine Phosphatases
Zhang, Zhong YinZhang, Zhong YinWang, YuanWang, YuanDixon, Jack and Dixon, Jack
Proceedings of the National Academy of Sciences of the United States of America, vol. 91, (no. 5), pp. 1627, 19940301. | Journal Article
 
The Cys(X)5Arg Catalytic Motif in Phosphoester Hydrolysis
Zhang, Z. FZhang, Zhong YinWang, YuanWang, YWu, LWu, LiFauman, Eric BFauman, E BStuckey, J AStuckey, Jeanne ASchubert, H LSchubert, Heidi LSaper, Mark ASaper, Mark ADixon, Jack E and Dixon, Jack E
Biochemistry, vol. 33, (no. 51), pp. 15270, 19941201. | Journal Article
1993
A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides
Zhang, Z. FZhang, Zhong YinMACLEAN, DMaclean, DTHIEME-SEFLER, A. MThieme-Sefler, A MROESKE, R. WRoeske, R WDIXON, J. E and Dixon, Jack E
Analytical biochemistry, vol. 211, (no. 1), pp. 15, 1993-May-15. | Journal Article
 
Substrate Specificity of the Protein Tyrosine Phosphatases
Zhang, Zhong YinZhang, Z. FThieme-Sefler, AndreaThieme-Sefler, A MMaclean, DerekMaclean, DMcNamara, D JMcNamara, DennisDobrusin, E MDobrusin, EllenSawyer, T KSawyer, TomiDixon, Jack and Dixon, Jack E
Proceedings of the National Academy of Sciences of the United States of America, vol. 90, (no. 10), pp. 4450, 19930515. | Journal Article
1992
Expression, purification, and physicochemical characterization of a recombinant Yersinia protein tyrosine phosphatase
Zhang, Z. FZhang, Zhong YinClemens, James CCLEMENS, J. CSchubert, H LSCHUBERT, H. LStuckey, J ASTUCKEY, J. AFischer, M WFISCHER, M. W. FHume, D MHUME, D. MSAPER, M. ASaper, Mark ADixon, Jack E and DIXON, J. E
The Journal of biological chemistry, vol. 267, (no. 33), pp. 23766, 1992-11-25. | Journal Article