54 Publications (Page 1 of 3)
2021
Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function
Capitano, Maegan LCapitano, Maegan LCapitano, Maegan LCapitano, Maegan LCapitano, Maegan LMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FCooper, ScottCooper, ScottCooper, ScottCooper, ScottCooper, ScottGuo, BinGuo, BinGuo, BinGuo, BinGuo, BinHuang, XinxinHuang, XinxinHuang, XinxinHuang, XinxinHuang, XinxinGunawan, Andrea MGunawan, Andrea MGunawan, Andrea MGunawan, Andrea MGunawan, Andrea MSampson, CarolSampson, CarolSampson, CarolSampson, CarolSampson, CarolRopa, JamesRopa, JamesRopa, JamesRopa, JamesRopa, JamesSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MBroxmeyer, Hal EBroxmeyer, Hal EBroxmeyer, Hal EBroxmeyer, Hal E and Broxmeyer, Hal E
Journal of Clinical Investigation, vol. 131, (no. 1), pp. 1-13, Jan 2021. | Journal Article
2020
Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects
Singh, PratibhaSingh, PratibhaSingh, PratibhaKacena, Melissa AKacena, Melissa AKacena, Melissa AOrschell, Christie MOrschell, Christie MOrschell, Christie MPelus, Louis MPelus, Louis M and Pelus, Louis M
Stem Cell Reviews and Reports, 2020-05-16. | Journal Article
 
Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?
Broxmeyer, Hal ELiu, YanLiu, YanLiu, YanKapur, ReubenOrschell, Christie MOrschell, Christie MOrschell, Christie MAljoufi, ArafatArafat, AljoufiArafat, AljoufiRopa, James PRopa, James PRopa, James PTrinh, ThaoBurns, SarahBurns, SarahBurns, SarahCapitano, Maegan LCapitano, Maegan L and Capitano, Maegan L
Stem Cell Reviews and Reports, vol. 16, (no. 6), pp. 1020-1048, Dec 2020. | Journal Article
2019
Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass
Maupin, Kevin AMaupin, Kevin AMaupin, Kevin AMaupin, Kevin AMaupin, Kevin AHimes, Evan RHimes, Evan RHimes, Evan RHimes, Evan RHimes, Evan RPlett, Artur PPlett, Artur PPlett, Artur PPlett, Artur PPlett, Artur PChua, Hui LinChua, Hui LinChua, Hui LinChua, Hui LinChua, Hui LinSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaSingh, PratibhaGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepGhosh, JoydeepMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FMohamad, Safa FAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiAbeysekera, IrushiFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaSampson, CarolSampson, CarolSampson, CarolSampson, CarolSampson, CarolHong, Jung-MinHong, Jung-MinHong, Jung-MinHong, Jung-MinHong, Jung-MinChildress, PaulChildress, PaulChildress, PaulChildress, PaulChildress, PaulAlvarez, MartaAlvarez, MartaAlvarez, MartaAlvarez, MartaAlvarez, MartaSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MPelus, Louis MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa A and Kacena, Melissa A
Bone, vol. 127, pp. 459, October 2019. | Journal Article
 
Cardiac and Renal Delayed Effects of Acute Radiation Exposure: Organ Differences in Vasculopathy, Inflammation, Senescence and Oxidative Balance
Unthank, Joseph LUnthank, Joseph LOrtiz, MiguelOrtiz, MiguelTrivedi, HinaTrivedi, HinaPelus, Louis MPelus, Louis MSampson, Carol HSampson, Carol HSellamuthu, RajendranSellamuthu, RajendranFisher, AlexaFisher, AlexaChua, Hui LinChua, Hui LinPlett, ArturPlett, ArturOrschell, Christie MOrschell, Christie MCohen, Eric PCohen, Eric PMiller, Steven J and Miller, Steven J
Radiation research, vol. 191, (no. 5), pp. 397, 2019-05-00. | Journal Article
 
Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype
Capitano, Maegan LCapitano, Maegan LCapitano, Maegan LCapitano, Maegan LCapitano, Maegan LCooper, ScottCooper, ScottCooper, ScottCooper, ScottCooper, ScottGuo, BinGuo, BinGuo, BinGuo, BinGuo, BinHuang, XinxinHuang, XinxinHuang, XinxinHuang, XinxinHuang, XinxinSampson, CarolSampson, CarolSampson, CarolSampson, CarolSampson, CarolMohamad, SafaMohamad, SafaMohamad, SafaMohamad, SafaMohamad, SafaSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MOrschell, Christie MBroxmeyer, Hal EBroxmeyer, Hal EBroxmeyer, Hal EBroxmeyer, Hal E and Broxmeyer, Hal E
Blood, vol. 134, (no. Supplement_1), pp. 1202, 2019-11-13. | Journal Article
 
Effect of Sex on Biomarker Response in a Mouse Model of the Hematopoietic Acute Radiation Syndrome
Jones, JaceAlloush, JennaSellamuthu, RajendranChua, HuiMacVittie, ThomasOrschell, Christie and Kane, Maureen
Health Physics, vol. 116, (no. 4), pp. 502, 2019-April. | Journal Article
 
Lifelong Residual bone Marrow Damage in Murine Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS): A Compilation of Studies Comprising the Indiana University Experience
Chua, HuiChua, HuiPlett, PPlett, PFisher, AlexaFisher, AlexaSampson, CarolSampson, CarolVemula, SasidharVemula, SasidharFeng, HailinFeng, HailinSellamuthu, RajendranSellamuthu, RajendranWu, TongWu, TongMacVittie, ThomasMacVittie, ThomasOrschell, Christie and Orschell, Christie
Health Physics, vol. 116, (no. 4), pp. 557, 2019-April. | Journal Article
2018
Characterization and Etiology of Swollen Muzzles in Irradiated Mice.
Garrett, JoySampson, Carol HPlett, P ArturCrisler, RobinParker, JeffreyVenezia, RichardChua, Hui LinHickman, Debra LBooth, CatherineMacVittie, ThomasOrschell, Christie M and Dynlacht, Joseph R
Radiation research, October 19, 2018. | Journal Article
 
Enhanced survival of lethally irradiated mice given pegylated G-CSF, GM-CSF, and IL-11 with lisinopril via modulation of the hematopoietic cytokines TGF[Symbol]-1 and RANTES
Walker, BrettWalker, BrettWu, TongWu, TongPlett, Paul APlett, Paul AChua, Hui LChua, Hui LFeng, HailinFeng, HailinOrschell, Christie and Orschell, Christie
Proceedings of IMPRS, vol. 1, (no. 1), 2018-12-07. | Journal Article
2017
An oral Hemokine TM , α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo
Faller, Douglas VFaller, Douglas VCastaneda, Serguei ACastaneda, Serguei AZhou, DaohongZhou, DaohongVedamony, MerrilineVedamony, MerrilineNewburger, Peter ENewburger, Peter EWhite, Gary LWhite, Gary LKosanke, StanleyKosanke, StanleyPlett, P ArturPlett, P ArturOrschell, Christie MOrschell, Christie MBoosalis, Michael SBoosalis, Michael SPerrine, Susan P and Perrine, Susan P
Blood cells, molecules & diseases, vol. 63, pp. 1, 2017-03-00. | Journal Article
 
An oral HemokineTM, α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo
Faller, Douglas VFaller, Douglas VCastaneda, Serguei ACastaneda, Serguei AZhou, DaohongZhou, DaohongVedamony, MerrilineVedamony, MerrilineNewburger, Peter ENewburger, Peter EWhite, Gary LWhite, Gary LKosanke, StanleyKosanke, StanleyPlett, P. ArturPlett, P. ArturOrschell, Christie MOrschell, Christie MBoosalis, Michael SBoosalis, Michael SPerrine, Susan P and Perrine, Susan P
Blood Cells, Molecules, and Diseases, vol. 63, pp. 8, 2017-03-00. | Journal Article
 
Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding.
Dynlacht, Joseph RDynlacht, Joseph RDynlacht, Joseph RGarrett, JoyGarrett, JoyGarrett, JoyJoel, RebeccaJoel, RebeccaJoel, RebeccaLane, KatharinaLane, KatharinaLane, KatharinaMendonca, Marc SMendonca, Marc SMendonca, Marc SOrschell, Christie MOrschell, Christie M and Orschell, Christie M
Radiation research, April 24, 2017. | Journal Article
2016
Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs.
Fish, Brian LGao, FengNarayanan, JayashreeBergom, CarmenJacobs, Elizabeth RCohen, Eric PMoulder, John EOrschell, Christie M and Medhora, Meetha
Health physics, vol. 111, (no. 5), pp. 410-419, November 2016. | Journal Article
 
Prostaglandin E2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation
Patterson, Andrea MPatterson, Andrea MPatterson, Andrea MSingh, PratibhaSingh, PratibhaSingh, PratibhaLi, HonggeLi, HonggeLi, HonggeChua, Hui LinChua, Hui LinChua, Hui LinFisher, AlexaFisher, AlexaFisher, AlexaSampson, CarolSampson, CarolSampson, CarolPlett, ArturPlett, ArturPlett, ArturOrschell, Christie MOrschell, Christie MOrschell, Christie MPelus, Louis MPelus, Louis M and Pelus, Louis M
Blood, vol. 128, (no. 22), pp. 1481, 2016-12-02. | Journal Article
 
Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air
Broxmeyer, Hal EBroxmeyer, Hal EBroxmeyer, Hal ECapitano, Maegan LCapitano, Maegan LCapitano, Maegan LO'leary, Heather AO'leary, Heather AO'leary, Heather ACooper, ScottCooper, ScottCooper, ScottChua, Hui LinChua, Hui LinChua, Hui LinPlett, ArturPlett, ArturPlett, ArturOrschell, Christie MOrschell, Christie M and Orschell, Christie M
Blood, vol. 128, (no. 22), pp. 5051, 2016-12-02. | Journal Article
2015
Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to <10 Gy Total Body Irradiation.
Unthank, JosephUnthank, JosephUnthank, Joseph LUnthank, JosephUnthank, JosephMiller, StevenMiller, Steven JMiller, StevenMiller, StevenMiller, StevenQuickery, ArielQuickery, Ariel KQuickery, ArielQuickery, ArielQuickery, ArielFerguson, EthanFerguson, Ethan LFerguson, EthanFerguson, EthanFerguson, EthanWang, MeijingWang, MeijingWang, MeijingWang, MeijingWang, MeijingSampson, CarolSampson, CarolSampson, CarolSampson, Carol HSampson, CarolChua, HuiChua, Hui LinChua, HuiChua, HuiChua, HuiDiStasi, MatthewDiStasi, Matthew RDiStasi, MatthewDiStasi, MatthewDiStasi, MatthewFeng, HailinFeng, HailinFeng, HailinFeng, HailinFeng, HailinFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaFisher, AlexaKatz, BarryKatz, BarryKatz, BarryKatz, BarryKatz, Barry PPlett, PPlett, P ArturPlett, PPlett, PPlett, PSandusky, George ESandusky, GeorgeSandusky, GeorgeSandusky, GeorgeSandusky, GeorgeSellamuthu, RajendranSellamuthu, RajendranSellamuthu, RajendranSellamuthu, RajendranSellamuthu, RajendranVemula, SasidharVemula, SasidharVemula, SasidharVemula, SasidharVemula, SasidharCohen, Eric PCohen, EricCohen, EricCohen, EricCohen, EricMacVittie, ThomasMacVittie, ThomasMacVittie, Thomas JMacVittie, ThomasMacVittie, ThomasOrschell, Christie MOrschell, ChristieOrschell, ChristieOrschell, Christie and Orschell, Christie
Health physics, vol. 109, (no. 5), pp. 511-521, November 2015. | Journal Article
 
Prostaglandin E2 Signaling through EP4 Receptor Promotes Hematopoietic Stem Cell Niche Regeneration and Enhances Hematopoietic Recovery
Singh, PratibhaSingh, PratibhaOrschell, Christie MOrschell, Christie MPelus, Louis M and Pelus, Louis M
Blood, vol. 126, (no. 23), pp. 784, 2015-12-03. | Journal Article
 
Relationships between renal parameters and serum and urine markers of inflammation in those with and without HIV infection.
Shinha, TakashiMi, DemingLiu, ZiyueOrschell, Christie MLederman, Michael M and Gupta, Samir K
AIDS research and human retroviruses, vol. 31, (no. 4), pp. 375-383, April 2015. | Journal Article
 
The H-ARS Dose Response Relationship (DRR): Validation and Variables.
Plett, P ArturSampson, Carol HChua, Hui LinJackson, WilliamVemula, SasidharSellamuthu, RajendranFisher, AlexaFeng, HailinWu, TongMacVittie, Thomas J and Orschell, Christie M
Health physics, vol. 109, (no. 5), pp. 391-398, November 2015. | Journal Article
2014
1612Intrarenal and Systemic Inflammation and HIV-related Renal Disease
Shinha, TakashiShinha, TakashiMi, DemingMi, DemingLiu, ZiyueLiu, ZiyueOrschell, ChristieOrschell, ChristieLederman, MichaelLederman, MichaelGupta, Samir and Gupta, Samir
Open Forum Infectious Diseases, vol. 1, (no. suppl_1), pp. S430, 2014-00-00. | Journal Article
 
Mass Spectrometry Imaging Enriches Biomarker Discovery Approaches with Candidate Mapping
Scott, Alison JJones, Jace WOrschell, Christie MMacvittie, Thomas JKane, Maureen and Ernst, Robert
Health Physics, vol. 106, (no. 1), Jan 2014. | Journal Article
 
Multiplex Cytokine Analysis after Cyclophosphamide/Fludarabine Nonmyeloablative Allogeneic Hematopoeitic Cell Transplantation
Khawaja, Muhammad RizwanOrschell, Christie MHardesty, Brandon MBurke, Brice CPerkins, Susan M and Nelson, Robert
Blood, vol. 124, (no. 21), pp. 1148, 2014-12-06. | Journal Article
 
PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), AND IL-11 (BBT-059) Analogs Enhance Survival and Hematopoietic Cell Recovery in a Mouse Model of the Hematopoietic Syndrome of the Acute Radiation Syndrome
Plett, Paul APlett, PaulChua, HuiChua, Hui LSampson, Carol HSampson, CarolKatz, Barry PKatz, BarryFam, ChristineFam, Christine MAnderson, Lana JAnderson, LanaCox, George NCox, GeorgeOrschell, Christie M and Orschell, Christie
Health Physics, vol. 106, (no. 1), Jan 2014. | Journal Article
 
Prognostic biomarkers for acute graft-versus-host disease risk after cyclophosphamide-fludarabine nonmyeloablative allotransplantation.
Nelson, Robert PKhawaja, Muhammad RizwanPerkins, Susan MElmore, LindseyMumaw, Christen LOrschell, Christie and Paczesny, Sophie
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, vol. 20, (no. 11), pp. 1861-1864, November 2014. | Journal Article