54 Publications (Page 1 of 3)
2021
Mitigating oxygen stress enhances aged mouse hematopoietic stem cell numbers and function
Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Gunawan, Andrea M⋅Gunawan, Andrea M⋅Gunawan, Andrea M⋅Gunawan, Andrea M⋅Gunawan, Andrea M⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Ropa, James⋅Ropa, James⋅Ropa, James⋅Ropa, James⋅Ropa, James⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E and Broxmeyer, Hal E
Journal of Clinical Investigation, vol. 131, (no. 1), pp. 1-13, Jan 2021. | Journal Article
2020
Aging-Related Reduced Expression of CXCR4 on Bone Marrow Mesenchymal Stromal Cells Contributes to Hematopoietic Stem and Progenitor Cell Defects
Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Kacena, Melissa A⋅Kacena, Melissa A⋅Kacena, Melissa A⋅Kacena, Melissa A⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M and Pelus, Louis M
Stem Cell Reviews and Reports, 2020-05-16. | Journal Article
 
Fate of Hematopoiesis During Aging. What Do We Really Know, and What are its Implications?
⋅Broxmeyer, Hal E⋅⋅Liu, Yan⋅Liu, Yan⋅Liu, Yan⋅Kapur, Reuben⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Arafat, Aljoufi⋅Aljoufi, Arafat⋅Arafat, Aljoufi⋅Ropa, James P⋅Ropa, James P⋅Ropa, James P⋅Trinh, Thao⋅Burns, Sarah⋅Burns, Sarah⋅Burns, Sarah⋅Capitano, Maegan L⋅Capitano, Maegan L and Capitano, Maegan L
Stem Cell Reviews and Reports, vol. 16, (no. 6), pp. 1020-1048, Dec 2020. | Journal Article
2019
Aging negatively impacts the ability of megakaryocytes to stimulate osteoblast proliferation and bone mass
Maupin, Kevin A⋅Maupin, Kevin A⋅Maupin, Kevin A⋅Maupin, Kevin A⋅Maupin, Kevin A⋅Himes, Evan R⋅Himes, Evan R⋅Himes, Evan R⋅Himes, Evan R⋅Himes, Evan R⋅Plett, Artur P⋅Plett, Artur P⋅Plett, Artur P⋅Plett, Artur P⋅Plett, Artur P⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Ghosh, Joydeep⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Mohamad, Safa F⋅Abeysekera, Irushi⋅Abeysekera, Irushi⋅Abeysekera, Irushi⋅Abeysekera, Irushi⋅Abeysekera, Irushi⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Hong, Jung-Min⋅Hong, Jung-Min⋅Hong, Jung-Min⋅Hong, Jung-Min⋅Hong, Jung-Min⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Childress, Paul⋅Alvarez, Marta⋅Alvarez, Marta⋅Alvarez, Marta⋅Alvarez, Marta⋅Alvarez, Marta⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Bruzzaniti, Angela⋅Bruzzaniti, Angela⋅Bruzzaniti, Angela⋅Bruzzaniti, Angela⋅Bruzzaniti, Angela⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Pelus, Louis M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Kacena, Melissa A⋅Kacena, Melissa A⋅Kacena, Melissa A⋅Kacena, Melissa A and Kacena, Melissa A
Bone, vol. 127, pp. 459, October 2019. | Journal Article
 
Cardiac and Renal Delayed Effects of Acute Radiation Exposure: Organ Differences in Vasculopathy, Inflammation, Senescence and Oxidative Balance
Unthank, Joseph L.⋅Unthank, Joseph L⋅Unthank, Joseph L⋅Ortiz, Miguel⋅Ortiz, Miguel⋅Ortiz, Miguel⋅Trivedi, Hina⋅Trivedi, Hina⋅Trivedi, Hina⋅Pelus, Louis M.⋅Pelus, Louis M⋅Pelus, Louis M⋅Sampson, Carol H⋅Sampson, Carol H⋅Sampson, Carol H.⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Plett, Artur⋅Plett, Artur⋅Plett, Artur⋅Orschell, Christie M.⋅Orschell, Christie M⋅Orschell, Christie M⋅Cohen, Eric P⋅Cohen, Eric P.⋅Cohen, Eric P⋅Miller, Steven J.⋅Miller, Steven J and Miller, Steven J
Radiation research, vol. 191, (no. 5), pp. 397, 2019-05-00. | Journal Article
 
Collection and Processing of Bone Marrow at 3% Oxygen Significantly Alters the Manifestation of Aged Mouse Hematopoietic Stem Cell Phenotype
Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Guo, Bin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Huang, Xinxin⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Mohamad, Safa⋅Mohamad, Safa⋅Mohamad, Safa⋅Mohamad, Safa⋅Mohamad, Safa⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Srour, Edward F⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E and Broxmeyer, Hal E
Blood, vol. 134, (no. Supplement_1), pp. 1202, 2019-11-13. | Journal Article
 
Effect of Sex on Biomarker Response in a Mouse Model of the Hematopoietic Acute Radiation Syndrome
Jones, J.W.⋅Jones, Jace⋅Alloush, J.⋅Alloush, Jenna⋅Sellamuthu, R.⋅Sellamuthu, Rajendran⋅Chua, Hui⋅Chua, H.L.⋅MacVittie, Thomas⋅Macvittie, T.J.⋅Orschell, C.M.⋅Orschell, Christie⋅Kane, Maureen and Kane, M.A.
Health Physics, vol. 116, (no. 4), pp. 502, 2019-April. | Journal Article
 
Lifelong Residual bone Marrow Damage in Murine Survivors of the Hematopoietic Acute Radiation Syndrome (H-ARS): A Compilation of Studies Comprising the Indiana University Experience
Chua, Hui⋅Chua, Hui⋅Plett, P⋅Plett, P⋅Fisher, Alexa⋅Fisher, Alexa⋅Sampson, Carol⋅Sampson, Carol⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Feng, Hailin⋅Feng, Hailin⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Wu, Tong⋅Wu, Tong⋅MacVittie, Thomas⋅MacVittie, Thomas⋅Orschell, Christie and Orschell, Christie
Health Physics, vol. 116, (no. 4), pp. 557, 2019-April. | Journal Article
2018
Characterization and Etiology of Swollen Muzzles in Irradiated Mice.
Garrett, Joy⋅Sampson, Carol H⋅Plett, P Artur⋅Crisler, Robin⋅Parker, Jeffrey⋅Venezia, Richard⋅Chua, Hui Lin⋅Hickman, Debra L⋅Booth, Catherine⋅MacVittie, Thomas⋅Orschella, Christie M⋅Orschell, Christie M⋅Dynlachta, Joseph R and Dynlacht, Joseph R
Radiation research, October 19, 2018. | Journal Article
 
Enhanced survival of lethally irradiated mice given pegylated G-CSF, GM-CSF, and IL-11 with lisinopril via modulation of the hematopoietic cytokines TGF[Symbol]-1 and RANTES
Walker, Brett⋅Walker, Brett⋅Wu, Tong⋅Wu, Tong⋅Plett, Paul A⋅Plett, Paul A⋅Chua, Hui L⋅Chua, Hui L⋅Feng, Hailin⋅Feng, Hailin⋅Orschell, Christie and Orschell, Christie
Proceedings of IMPRS, vol. 1, (no. 1), 2018-12-07. | Journal Article
2017
An oral Hemokine TM , α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo
Faller, Douglas V⋅Faller, Douglas V⋅Castaneda, Serguei A⋅Castaneda, Serguei A⋅Zhou, Daohong⋅Zhou, Daohong⋅Vedamony, Merriline⋅Vedamony, Merriline⋅Newburger, Peter E⋅Newburger, Peter E⋅White, Gary L⋅White, Gary L⋅Kosanke, Stanley⋅Kosanke, Stanley⋅Plett, P Artur⋅Plett, P Artur⋅Orschell, Christie M⋅Orschell, Christie M⋅Boosalis, Michael S⋅Boosalis, Michael S⋅Perrine, Susan P and Perrine, Susan P
Blood cells, molecules & diseases, vol. 63, pp. 1, 2017-03-00. | Journal Article
 
An oral HemokineTM, α-methylhydrocinnamate, enhances myeloid and neutrophil recovery following irradiation in vivo
Faller, Douglas V⋅Faller, Douglas V⋅Castaneda, Serguei A⋅Castaneda, Serguei A⋅Zhou, Daohong⋅Zhou, Daohong⋅Vedamony, Merriline⋅Vedamony, Merriline⋅Newburger, Peter E⋅Newburger, Peter E⋅White, Gary L⋅White, Gary L⋅Kosanke, Stanley⋅Kosanke, Stanley⋅Plett, P. Artur⋅Plett, P. Artur⋅Orschell, Christie M⋅Orschell, Christie M⋅Boosalis, Michael S⋅Boosalis, Michael S⋅Perrine, Susan P and Perrine, Susan P
Blood Cells, Molecules, and Diseases, vol. 63, pp. 8, 2017-03-00. | Journal Article
 
Further Characterization of the Mitigation of Radiation Lethality by Protective Wounding.
Dynlacht, Joseph R⋅Dynlacht, Joseph R⋅Dynlacht, Joseph R⋅Garrett, Joy⋅Garrett, Joy⋅Garrett, Joy⋅Joel, Rebecca⋅Joel, Rebecca⋅Joel, Rebecca⋅Lane, Katharina⋅Lane, Katharina⋅Lane, Katharina⋅Mendonca, Marc S⋅Mendonca, Marc S⋅Mendonca, Marc S⋅Orschell, Christie M⋅Orschell, Christie M and Orschell, Christie M
Radiation research, April 24, 2017. | Journal Article
2016
Combined Hydration and Antibiotics with Lisinopril to Mitigate Acute and Delayed High-dose Radiation Injuries to Multiple Organs.
Fish, Brian L⋅Gao, Feng⋅Narayanan, Jayashree⋅Bergom, Carmen⋅Jacobs, Elizabeth R⋅Cohen, Eric P⋅Moulder, John E⋅Orschell, Christie M and Medhora, Meetha
Health physics, vol. 111, (no. 5), pp. 410-419, November 2016. | Journal Article
 
Prostaglandin E2 Promotes Early Bone Marrow Reconstitution for Survival after Lethal Irradiation
Patterson, Andrea M⋅Patterson, Andrea M⋅Patterson, Andrea M⋅Singh, Pratibha⋅Singh, Pratibha⋅Singh, Pratibha⋅Li, Hongge⋅Li, Hongge⋅Li, Hongge⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Plett, Artur⋅Plett, Artur⋅Plett, Artur⋅Orschell, Christie M⋅Orschell, Christie M⋅Orschell, Christie M⋅Pelus, Louis M⋅Pelus, Louis M and Pelus, Louis M
Blood, vol. 128, (no. 22), pp. 1481, 2016-12-02. | Journal Article
 
Re-Evaluation of Age-Related Dysregulation of Hematopoiesis Based on Oxygen Induced Changes Associated with Cell Collection/Processing in Ambient Air
Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Broxmeyer, Hal E⋅Capitano, Maegan L⋅Capitano, Maegan L⋅Capitano, Maegan L⋅O'leary, Heather A⋅O'leary, Heather A⋅O'leary, Heather A⋅Cooper, Scott⋅Cooper, Scott⋅Cooper, Scott⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Chua, Hui Lin⋅Plett, Artur⋅Plett, Artur⋅Plett, Artur⋅Orschell, Christie M⋅Orschell, Christie M and Orschell, Christie M
Blood, vol. 128, (no. 22), pp. 5051, 2016-12-02. | Journal Article
2015
Delayed Effects of Acute Radiation Exposure in a Murine Model of the H-ARS: Multiple-Organ Injury Consequent to <10 Gy Total Body Irradiation.
Unthank, Joseph⋅Unthank, Joseph L⋅Unthank, Joseph⋅Unthank, Joseph⋅Unthank, Joseph⋅Miller, Steven⋅Miller, Steven⋅Miller, Steven⋅Miller, Steven J⋅Miller, Steven⋅Quickery, Ariel⋅Quickery, Ariel K⋅Quickery, Ariel⋅Quickery, Ariel⋅Quickery, Ariel⋅Ferguson, Ethan⋅Ferguson, Ethan⋅Ferguson, Ethan L⋅Ferguson, Ethan⋅Ferguson, Ethan⋅Wang, Meijing⋅Wang, Meijing⋅Wang, Meijing⋅Wang, Meijing⋅Wang, Meijing⋅Sampson, Carol⋅Sampson, Carol H⋅Sampson, Carol⋅Sampson, Carol⋅Sampson, Carol⋅Chua, Hui⋅Chua, Hui⋅Chua, Hui Lin⋅Chua, Hui⋅Chua, Hui⋅DiStasi, Matthew⋅DiStasi, Matthew⋅DiStasi, Matthew⋅DiStasi, Matthew⋅DiStasi, Matthew R⋅Feng, Hailin⋅Feng, Hailin⋅Feng, Hailin⋅Feng, Hailin⋅Feng, Hailin⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Fisher, Alexa⋅Katz, Barry⋅Katz, Barry P⋅Katz, Barry⋅Katz, Barry⋅Katz, Barry⋅Plett, P Artur⋅Plett, P⋅Plett, P⋅Plett, P⋅Plett, P⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George⋅Sandusky, George E⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Sellamuthu, Rajendran⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Vemula, Sasidhar⋅Cohen, Eric⋅Cohen, Eric P⋅Cohen, Eric⋅Cohen, Eric⋅Cohen, Eric⋅MacVittie, Thomas⋅MacVittie, Thomas⋅MacVittie, Thomas⋅MacVittie, Thomas⋅MacVittie, Thomas J⋅Orschell, Christie⋅Orschell, Christie⋅Orschell, Christie⋅Orschell, Christie and Orschell, Christie M
Health physics, vol. 109, (no. 5), pp. 511-521, November 2015. | Journal Article
 
Prostaglandin E2 Signaling through EP4 Receptor Promotes Hematopoietic Stem Cell Niche Regeneration and Enhances Hematopoietic Recovery
Singh, Pratibha⋅Singh, Pratibha⋅Orschell, Christie M⋅Orschell, Christie M⋅Pelus, Louis M and Pelus, Louis M
Blood, vol. 126, (no. 23), pp. 784, 2015-12-03. | Journal Article
 
Relationships between renal parameters and serum and urine markers of inflammation in those with and without HIV infection.
Shinha, Takashi⋅Mi, Deming⋅Liu, Ziyue⋅Orschell, Christie M⋅Lederman, Michael M and Gupta, Samir K
AIDS research and human retroviruses, vol. 31, (no. 4), pp. 375-383, April 2015. | Journal Article
 
The H-ARS Dose Response Relationship (DRR): Validation and Variables.
Plett, P Artur⋅Sampson, Carol H⋅Chua, Hui Lin⋅Jackson, William⋅Vemula, Sasidhar⋅Sellamuthu, Rajendran⋅Fisher, Alexa⋅Feng, Hailin⋅Wu, Tong⋅MacVittie, Thomas J and Orschell, Christie M
Health physics, vol. 109, (no. 5), pp. 391-398, November 2015. | Journal Article
2014
1612Intrarenal and Systemic Inflammation and HIV-related Renal Disease
Shinha, Takashi⋅Shinha, Takashi⋅Mi, Deming⋅Mi, Deming⋅Liu, Ziyue⋅Liu, Ziyue⋅Orschell, Christie⋅Orschell, Christie⋅Lederman, Michael⋅Lederman, Michael⋅Gupta, Samir and Gupta, Samir
Open Forum Infectious Diseases, vol. 1, (no. suppl_1), pp. S430, 2014-00-00. | Journal Article
 
Mass Spectrometry Imaging Enriches Biomarker Discovery Approaches with Candidate Mapping
Scott, Alison J⋅Scott, A.J.⋅Jones, J.W.⋅Jones, Jace W⋅Orschell, C.M.⋅Orschell, Christie M⋅Macvittie, Thomas J⋅Macvittie, T.J.⋅Kane, Maureen⋅Kane, M.A.⋅Ernst, R.K. and Ernst, Robert
Health Physics, vol. 106, (no. 1), Jan 2014. | Journal Article
 
Multiplex Cytokine Analysis after Cyclophosphamide/Fludarabine Nonmyeloablative Allogeneic Hematopoeitic Cell Transplantation
Khawaja, Muhammad Rizwan⋅Orschell, Christie M⋅Hardesty, Brandon M⋅Burke, Brice C⋅Perkins, Susan M and Nelson, Robert
Blood, vol. 124, (no. 21), pp. 1148, 2014-12-06. | Journal Article
 
PEGylated G-CSF (BBT-015), GM-CSF (BBT-007), AND IL-11 (BBT-059) Analogs Enhance Survival and Hematopoietic Cell Recovery in a Mouse Model of the Hematopoietic Syndrome of the Acute Radiation Syndrome
Plett, Paul A⋅Plett, Paul⋅Chua, Hui⋅Chua, Hui L⋅Sampson, Carol⋅Sampson, Carol H⋅Katz, Barry⋅Katz, Barry P⋅Fam, Christine⋅Fam, Christine M⋅Anderson, Lana J⋅Anderson, Lana⋅Cox, George⋅Cox, George N⋅Orschell, Christie and Orschell, Christie M
Health Physics, vol. 106, (no. 1), Jan 2014. | Journal Article
 
Prognostic biomarkers for acute graft-versus-host disease risk after cyclophosphamide-fludarabine nonmyeloablative allotransplantation.
Nelson, Robert P⋅Khawaja, Muhammad Rizwan⋅Perkins, Susan M⋅Elmore, Lindsey⋅Mumaw, Christen L⋅Orschell, Christie and Paczesny, Sophie
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation, vol. 20, (no. 11), pp. 1861-1864, November 2014. | Journal Article