110 Publications (Page 1 of 5)
2023
5‑Nitro-1,2-benzothiazol-3-amine and N‑Ethyl-1-[(ethylcarbamoyl)(5-nitro-1,2-benzothiazol-3-yl)amino]formamide Modulate α‑Synuclein and Tau Aggregation
Ramirez, Eduardo⋅Ramirez, Eduardo⋅Ganegamage, Susantha K.⋅Ganegamage, Susantha K.⋅Elbatrawy, Ahmed A.⋅Elbatrawy, Ahmed A.⋅Alnakhala, Heba⋅Alnakhala, Heba⋅Shimanaka, Kazuma⋅Shimanaka, Kazuma⋅Tripathi, Arati⋅Tripathi, Arati⋅Min, Sehong⋅Min, Sehong⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Dettmer, Ulf⋅Dettmer, Ulf⋅Fortin, Jessica S. and Fortin, Jessica S.
ACS omega, vol. 8, (no. 22), pp. 20115, 2023-Jun-06. | Journal Article
 
Discovery of 4-aminoindole carboxamide derivatives to curtail alpha-synuclein and tau isoform 2N4R oligomer formation
Ramirez, E.⋅Ramirez, Eduardo⋅Min, S.⋅Min, Sehong⋅Ganegamage, S.K.⋅Ganegamage, Susantha K.⋅Shimanaka, K.⋅Shimanaka, Kazuma⋅Sosa, Magaly Guzman⋅Sosa, M.G.⋅Dettmer, Ulf⋅Dettmer, U.⋅Rochet, Jean Christophe⋅Rochet, J.-C.⋅Fortin, Jessica S. and Fortin, J.S.
Results in Chemistry, vol. 5, pp. 100938, January 2023. | Journal Article
 
Protective effects of polyphenol-rich extracts against neurotoxicity elicited by paraquat or rotenone in cellular models of Parkinson's disease
Tambe, Mitali A⋅Tambe, Mitali A⋅de Rus Jacquet, Aurelie⋅de Rus Jacquet, Aurelie⋅Strathearn, Katherine E⋅Strathearn, Katherine E⋅Yousef, Gad G⋅Yousef, Gad G⋅Grace, Mary H⋅Grace, Mary H⋅Ferruzzi, Mario G⋅Ferruzzi, Mario G⋅Wu, Qingli⋅Wu, Qingli⋅Simon, James E⋅Simon, James E⋅Lila, Mary Ann⋅Lila, Mary Ann⋅Rochet, Jean Christophe and Rochet, Jean-Christophe
bioRxiv, 2023-Apr-27. | Journal Article
2022
Identification of Novel Kinases of Tau Using Fluorescence Complementation Mass Spectrometry (FCMS)
Kao, Der-Shyang⋅Kao, Der-Shyang⋅Du, Yanyan⋅Du, Yanyan⋅DeMarco, Andrew G⋅DeMarco, Andrew G⋅Min, Sehong⋅Min, Sehong⋅Hall, Mark C⋅Hall, Mark C⋅Rochet, Jean Christophe⋅Rochet, Jean-Christophe⋅Tao, W Andy and Tao, W Andy
Molecular & cellular proteomics, vol. 21, (no. 12), pp. 100441, 2022-12-01. | Journal Article
 
Shining a light on autophagy in neurodegenerative diseases
Chandran, Aswathy⋅Chandran, Aswathy⋅Rochet, Jean-Christophe and Rochet, Jean Christophe
The Journal of biological chemistry, vol. 298, (no. 1), pp. 101437, 2022-01-01. | Journal Article
2021
Hyperexcitability and Pharmacological Responsiveness of Cortical Neurons Derived from Human iPSCs Carrying Epilepsy-Associated Sodium Channel Nav1.2-L1342P Genetic Variant
Que, Zhefu⋅Que, Zhefu⋅Que, Zhefu⋅Que, Zhefu⋅Olivero-Acosta, Maria I⋅Olivero-Acosta, Maria I⋅Olivero-Acosta, Maria I⋅Olivero-Acosta, Maria I⋅Zhang, Jingliang⋅Zhang, Jingliang⋅Zhang, Jingliang⋅Zhang, Jingliang⋅Eaton, Muriel⋅Eaton, Muriel⋅Eaton, Muriel⋅Eaton, Muriel⋅Tukker, Anke M⋅Tukker, Anke M⋅Tukker, Anke M⋅Tukker, Anke M⋅Chen, Xiaoling⋅Chen, Xiaoling⋅Chen, Xiaoling⋅Chen, Xiaoling⋅Wu, Jiaxiang⋅Wu, Jiaxiang⋅Wu, Jiaxiang⋅Wu, Jiaxiang⋅Xie, Junkai⋅Xie, Junkai⋅Xie, Junkai⋅Xie, Junkai⋅Xiao, Tiange⋅Xiao, Tiange⋅Xiao, Tiange⋅Xiao, Tiange⋅Wettschurack, Kyle⋅Wettschurack, Kyle⋅Wettschurack, Kyle⋅Wettschurack, Kyle⋅Yunis, Layan⋅Yunis, Layan⋅Yunis, Layan⋅Yunis, Layan⋅Shafer, J Marshall⋅Shafer, J Marshall⋅Shafer, J Marshall⋅Shafer, J Marshall⋅Schaber, James A⋅Schaber, James A⋅Schaber, James A⋅Schaber, James A⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Bowman, Aaron B⋅Bowman, Aaron B⋅Bowman, Aaron B⋅Bowman, Aaron B⋅Yuan, Chongli⋅Yuan, Chongli⋅Yuan, Chongli⋅Yuan, Chongli⋅Huang, Zhuo⋅Huang, Zhuo⋅Huang, Zhuo⋅Huang, Zhuo⋅Hu, Chang-Deng⋅Hu, Chang-Deng⋅Hu, Chang-Deng⋅Hu, Chang-Deng⋅Trader, Darci J⋅Trader, Darci J⋅Trader, Darci J⋅Trader, Darci J⋅Skarnes, William C⋅Skarnes, William C⋅Skarnes, William C⋅Skarnes, William C⋅Yang, Yang⋅Yang, Yang⋅Yang, Yang and Yang, Yang
The Journal of neuroscience, vol. 41, (no. 49), pp. 10208, 2021-12-08. | Journal Article
 
Monitoring phagocytic uptake of amyloid β into glial cell lysosomes in real time
Prakash, Priya⋅Prakash, Priya⋅Jethava, Krupal P⋅Jethava, Krupal P⋅Korte, Nils⋅Korte, Nils⋅Izquierdo, Pablo⋅Izquierdo, Pablo⋅Favuzzi, Emilia⋅Favuzzi, Emilia⋅Rose, Indigo V. L⋅Rose, Indigo V. L⋅Guttenplan, Kevin A⋅Guttenplan, Kevin A⋅Manchanda, Palak⋅Manchanda, Palak⋅Dutta, Sayan⋅Dutta, Sayan⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Fishell, Gord⋅Fishell, Gord⋅Liddelow, Shane A⋅Liddelow, Shane A⋅Attwell, David⋅Attwell, David⋅Chopra, Gaurav and Chopra, Gaurav
Chemical science (Cambridge), vol. 12, (no. 32), pp. 1918, 20210818. | Journal Article
 
Neuroprotective mechanisms of red clover and soy isoflavones in Parkinson's disease models
de Rus Jacquet, Aurélie⋅de Rus Jacquet, Aurélie⋅Ambaw, Abeje⋅Ambaw, Abeje⋅Tambe, Mitali Arun⋅Tambe, Mitali Arun⋅Ma, Sin Ying⋅Ma, Sin Ying⋅Timmers, Michael⋅Timmers, Michael⋅Grace, Mary H⋅Grace, Mary H⋅Wu, Qing-Li⋅Wu, Qing-Li⋅Simon, James E⋅Simon, James E⋅McCabe, George P⋅McCabe, George P⋅Lila, Mary Ann⋅Lila, Mary Ann⋅Shi, Riyi⋅Shi, Riyi⋅Rochet, Jean-Christophe and Rochet, Jean Christophe
Food & function, vol. 12, (no. 23), pp. 127, 2021-11-29. | Journal Article
2020
Calcein Release Assay to Measure Membrane Permeabilization by Recombinant Alpha-Synuclein
Dutta, Sayan⋅Dutta, Sayan⋅Watson, Ben G⋅Watson, Ben G⋅Mattoo, Seema⋅Mattoo, Seema⋅Rochet, Jean-Christophe and Rochet, Jean Christophe
Bio-protocol, vol. 10, (no. 14), 2020-07-20. | Journal Article
 
Corrigendum to "DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits". Neurobiology of Disease 134 (2020) 104629
Solti, Katalin⋅Kuan, Wei-Li⋅Fórizs, Balázs⋅Kustos, Gergely⋅Mihály, Judith⋅Varga, Zoltán⋅Herberth, Balázs⋅Moravcsik, Éva⋅Kiss, Róbert⋅Kárpáti, Manuela⋅Mikes, Anna⋅Zhao, Yanyan⋅Imre, Tímea⋅Rochet, Jean Christophe⋅Aigbirhio, Franklin⋅Williams-Gray, Caroline H.⋅Barker, Roger A. and Tóth, Gergely
Neurobiology of disease, vol. 142, pp. 104971, August 2020. | Journal Article
 
DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits
Solti, Katalin⋅Kuan, Wei-Li⋅Fórizs, Balázs⋅Kustos, Gergely⋅Mihály, Judith⋅Varga, Zoltán⋅Herberth, Balázs⋅Moravcsik, Éva⋅Kiss, Róbert⋅Kárpáti, Manuela⋅Mikes, Anna⋅Zhao, Yanyan⋅Imre, Tímea⋅Rochet, Jean Christophe⋅Aigbirhio, Franklin⋅Williams-Gray, Caroline H⋅Barker, Roger A and Tóth, Gergely
Neurobiology of Disease, vol. 134, pp. 104629, February 2020. | Journal Article
 
In vitro AMPylation/Adenylylation of Alpha-synuclein by HYPE/FICD
Camara, Ali⋅Camara, Ali⋅Sanyal, Anwesha⋅Sanyal, Anwesha⋅Dutta, Sayan⋅Dutta, Sayan⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Mattoo, Seema and Mattoo, Seema
Bio-protocol, vol. 10, (no. 18), pp. e3760, 2020-09-20. | Journal Article
 
Localization of fluorescent targets in deep tissue with expanded beam illumination for studies of cancer and the brain
Bentz, Brian Z.⋅Bentz, Brian Z.⋅Bentz, Brian Z.⋅Bentz, Brian Z⋅Mahalingam, Sakkarapalayam M.⋅Mahalingam, Sakkarapalayam M⋅Mahalingam, Sakkarapalayam M.⋅Mahalingam, Sakkarapalayam M.⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Montenegro Larrea, Paola C.⋅Montenegro Larrea, Paola C.⋅Montenegro, Paola C⋅Montenegro Larrea, Paola C.⋅Cannon, Jason R.⋅Cannon, Jason R.⋅Cannon, Jason R.⋅Cannon, Jason R⋅Rochet, Jean Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Low, Philip S.⋅Low, Philip S.⋅Low, Philip S.⋅Low, Philip S⋅Webb, Kevin⋅Webb, Kevin⋅Webb, Kevin and Webb, Kevin J
IEEE Transactions on Medical Imaging, pp. 1, 20200205. | Journal Article
 
Neuromelanin Modulates Heterocyclic Aromatic Amine-Induced Dopaminergic Neurotoxicity
Lawana, Vivek⋅Lawana, Vivek⋅Um, Se Young⋅Um, Se Young⋅Rochet, Jean Christophe⋅Rochet, Jean-Christophe⋅Turesky, Robert J⋅Turesky, Robert J⋅Shannahan, Jonathan H⋅Shannahan, Jonathan H⋅Cannon, Jason R and Cannon, Jason R
Toxicological Sciences, vol. 173, (no. 1), pp. 188, 20200101. | Journal Article
 
Two C-terminal sequence variations determine differential neurotoxicity between human and mouse α-synuclein
Landeck, Natalie⋅Strathearn, Katherine E.⋅Ysselstein, Daniel⋅Buck, Kerstin⋅Dutta, Sayan⋅Banerjee, Siddhartha⋅Lv, Zhengjian⋅Hulleman, John D.⋅Hindupur, Jagadish⋅Lin, Li-Kai⋅Padalkar, Sonal⋅Stanciu, Lia A.⋅Lyubchenko, Yuri L.⋅Kirik, Deniz and Rochet, Jean Christophe
Molecular neurodegeneration, vol. 15, (no. 1), pp. 49, 2020-09-08. | Journal Article
2019
Alpha-Synuclein Is a Target of Fic-Mediated Adenylylation/AMPylation: Possible Implications for Parkinson's Disease
Sanyal, Anwesha⋅Sanyal, Anwesha⋅Sanyal, Anwesha⋅Dutta, Sayan⋅Dutta, Sayan⋅Dutta, Sayan⋅Camara, Ali⋅Camara, Ali⋅Camara, Ali⋅Chandran, Aswathy⋅Chandran, Aswathy⋅Chandran, Aswathy⋅Koller, Antonius⋅Koller, Antonius⋅Koller, Antonius⋅Watson, Ben G.⋅Watson, Ben G.⋅Watson, Ben G⋅Sengupta, Ranjan⋅Sengupta, Ranjan⋅Sengupta, Ranjan⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Ysselstein, Daniel⋅Montenegro, Paola⋅Montenegro, Paola⋅Montenegro, Paola⋅Cannon, Jason⋅Cannon, Jason⋅Cannon, Jason⋅Rochet, Jean Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Mattoo, Seema⋅Mattoo, Seema and Mattoo, Seema
Journal of Molecular Biology, vol. 431, (no. 12), pp. 2282, 2019-05-31. | Journal Article
 
Assembly of [alpha]-synuclein aggregates on phospholipid bilayers
Lv, Zhengjian⋅Hashemi, Mohtadin⋅Banerjee, Siddhartha⋅Zagorski, Karen⋅Rochet, Jean Christophe and Lyubchenko, Yuri
BBA - Proteins and Proteomics, vol. 1867, (no. 9), pp. 802, 20190901. | Journal Article
 
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
Tóth, Gergely⋅Neumann, Thomas⋅Berthet, Amandine⋅Masliah, Eliezer⋅Spencer, Brian⋅Tao, Jiahui⋅Jobling, Michael F⋅Gardai, Shyra J⋅Bertoncini, Carlos W⋅Cremades, Nunilo⋅Bova, Michael⋅Ballaron, Stephen⋅Chen, Xiao-Hua⋅Mao, Wenxian⋅Nguyen, Phuong⋅Tabios, Mariano C⋅Tambe, Mitali A⋅Rochet, Jean Christophe⋅Junker, Hans-Dieter⋅Schwizer, Daniel⋅Sekul, Renate⋅Ott, Inge⋅Anderson, John P⋅Szoke, Balazs⋅Hoffman, Wherly⋅Christodoulou, John⋅Yednock, Ted⋅Agard, David A⋅Schenk, Dale and McConlogue, Lisa
Scientific reports, vol. 9, (no. 1), pp. 14, 2019-11-18. | Journal Article
2018
Acrolein-mediated neuronal cell death and alpha-synuclein aggregation: Implications for Parkinson's disease
Ambaw, Abeje⋅Ambaw, Abeje⋅Ambaw, Abeje⋅Ambaw, Abeje⋅Zheng, Lingxing⋅Zheng, Lingxing⋅Zheng, Lingxing⋅Zheng, Lingxing⋅Tambe, Mitali A⋅Tambe, Mitali A.⋅Tambe, Mitali A⋅Tambe, Mitali A.⋅Strathearn, Katherine E.⋅Strathearn, Katherine E.⋅Strathearn, Katherine E⋅Strathearn, Katherine E⋅Acosta, Glen⋅Acosta, Glen⋅Acosta, Glen⋅Acosta, Glen⋅Hubers, Scott A.⋅Hubers, Scott A⋅Hubers, Scott A.⋅Hubers, Scott A⋅Liu, Fang⋅Liu, Fang⋅Liu, Fang⋅Liu, Fang⋅Herr, Seth A⋅Herr, Seth A.⋅Herr, Seth A⋅Herr, Seth A.⋅Tang, Jonathan⋅Tang, Jonathan⋅Tang, Jonathan⋅Tang, Jonathan⋅Truong, Alan⋅Truong, Alan⋅Truong, Alan⋅Truong, Alan⋅Walls, Elwood⋅Walls, Elwood⋅Walls, Elwood⋅Walls, Elwood⋅Pond, Amber⋅Pond, Amber⋅Pond, Amber⋅Pond, Amber⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Shi, Riyi⋅Shi, Riyi⋅Shi, Riyi and Shi, Riyi
Molecular and Cellular Neuroscience, vol. 88, pp. 82, April 2018. | Journal Article
 
Selective dopaminergic neurotoxicity of three heterocyclic amine subclasses in primary rat midbrain neurons
Cruz-Hernandez, Angela⋅Agim, Zeynep Sena⋅Montenegro, Paola C⋅McCabe, George P⋅Rochet, Jean Christophe and Cannon, Jason R
Neurotoxicology, vol. 65, pp. 84, March 2018. | Journal Article
2017
Aggregation of Amyloid Proteins at the Surface-Liquid Interface
Banerjee, Siddhartha⋅Hashemi, Mohtadin⋅Lv, Zhengjian⋅Maity, Sibaprasad⋅Rochet, Jean Christophe and Lyubchenko, Yuri
Biophysical Journal, vol. 112, (no. 3), pp. 365a, 2017-02-03. | Journal Article
 
A novel pathway for amyloids self-assembly in aggregates at nanomolar concentration mediated by the interaction with surfaces
Banerjee, Siddhartha⋅Hashemi, Mohtadin⋅Lv, Zhengjian⋅Maity, Sibaprasad⋅Rochet, Jean Christophe and Lyubchenko, Yuri L
Scientific reports, vol. 7, (no. 1), pp. 45592, 2017-03-30. | Journal Article
 
Endosulfine-alpha inhibits membrane-induced Alpha-synuclein aggregation and protects against Alpha-synuclein neurotoxicity
Ysselstein, Daniel⋅Dehay, Benjamin⋅Costantino, Isabel⋅Mc Cabe, George⋅Frosch, Matthew⋅George, Julia⋅Bezard, Erwan and Rochet, Jean Christophe
Acta Neuropathologica Communications, vol. 5, 2017. | Journal Article
 
Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity.
Ysselstein, Daniel⋅Ysselstein, Daniel⋅Dehay, Benjamin⋅Dehay, Benjamin⋅Costantino, Isabel M⋅Costantino, Isabel M⋅Frosch, Matthew P⋅Mc Cabe, George P⋅Frosch, Matthew P⋅George, Julia M⋅Bezard, Erwan⋅George, Julia M⋅Rochet, Jean-Christophe⋅Bezard, Erwan⋅Rochet, Jean Christophe and McCabe, Georges
Acta neuropathologica communications, vol. 5, (no. 1), pp. 3, January 10, 2017. | Journal Article
 
Lumbee traditional medicine: Neuroprotective activities of medicinal plants used to treat Parkinson's disease-related symptoms
de Rus Jacquet, Aurélie⋅de Rus Jacquet, Aurélie⋅Timmers, Michael⋅Timmers, Michael⋅Ma, Sin Ying⋅Ma, Sin Ying⋅Thieme, Andrew⋅Thieme, Andrew⋅McCabe, George P⋅McCabe, George P⋅Vest, Jay Hansford C⋅Vest, Jay Hansford C⋅Lila, Mary Ann⋅Lila, Mary Ann⋅Rochet, Jean Christophe and Rochet, Jean-Christophe
Journal of Ethnopharmacology, vol. 206, pp. 425, 2017-07-12. | Journal Article