110 Publications (Page 3 of 5)
2012
Effect of single amino acid substitution on oxidative modifications of the Parkinson's disease-related protein, DJ-1.
Madian, Ashraf G⋅Hindupur, Jagadish⋅Hulleman, John D⋅Diaz-Maldonado, Naomi⋅Mishra, Vartika R⋅Guigard, Emmanuel⋅Kay, Cyril M⋅Rochet, Jean Christophe and Regnier, Fred E
Molecular & cellular proteomics : MCP, vol. 11, (no. 2), pp. M111.010892, 2012/Feb. | Journal Article
 
Effect of Spermidine on Misfolding and Interactions of Alpha-Synuclein
Krasnoslobodtsev, Alexey V⋅Peng, Jie⋅Asiago, Josephat M⋅Hindupur, Jagadish⋅Rochet, Jean Christophe and Lyubchenko, Yuri L
PloS one, vol. 7, (no. 5), pp. e38099, 2012-00-00. | Journal Article
 
Molecular insights into Parkinson's disease.
Rochet, Jean Christophe⋅Hay, Bruce A and Guo, Ming
Progress in molecular biology and translational science, vol. 107, pp. 125-88, 2012. | Journal Article
 
New insights into lysosomal dysfunction in Parkinson’s disease: an emerging role for ATP13A2
Rochet, Jean Christophe
Movement disorders : official journal of the Movement Disorder Society, vol. 27, (no. 9), pp. 1092, 2012-Aug. | Journal Article
2011
Acid β-glucosidase mutants linked to gaucher disease, parkinson disease, and lewy body dementia alter α-synuclein processing
Cullen, Valerie⋅Cullen, Valerie⋅Sardi, S. Pablo⋅Sardi, S P⋅Ng, Juliana⋅Ng, Juliana⋅Xu, You Hai⋅Xu, You-Hai⋅Sun, Ying⋅Sun, Ying⋅Tomlinson, Julianna J⋅Tomlinson, Julianna J.⋅Kolodziej, Piotr⋅Kolodziej, Piotr⋅Kahn, Ilana⋅Kahn, Ilana⋅Saftig, Paul⋅Saftig, Paul⋅Woulfe, John⋅Woulfe, John⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Glicksman, Marcie A.⋅Glicksman, Marcie A⋅Cheng, Seng H.⋅Cheng, Seng H⋅Grabowski, Gregory A.⋅Grabowski, Gregory A⋅Shihabuddin, Lamya S.⋅Shihabuddin, Lamya S⋅Schlossmacher, Michael G and Schlossmacher, Michael G.
Annals of neurology, vol. 69, (no. 6), pp. 953, June 2011. | Journal Article
 
[alpha]-synuclein-induced tubule formation in lipid bilayers
Pandey, Anjan⋅Haque, Farzin⋅Rochet, Jean Christophe and Hovis, Jennifer
Journal of Physical Chemistry B, vol. 115, (no. 19), pp. 5886, 20110519. | Journal Article
 
Cyclin-G-associated kinase modifies α-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study.
Dumitriu, Alexandra⋅Pacheco, Chris D⋅Wilk, Jemma B⋅Strathearn, Katherine E⋅Latourelle, Jeanne C⋅Goldwurm, Stefano⋅Pezzoli, Gianni⋅Rochet, Jean Christophe⋅Lindquist, Susan L and Myers, Richard H
Human molecular genetics, vol. 20, (no. 8), pp. 1478-87, 2011/Apr/15. | Journal Article
 
α-Synuclein-induced tubule formation in lipid bilayers.
Pandey, Anjan P⋅Haque, Farzin⋅Rochet, Jean Christophe and Hovis, Jennifer S
The journal of physical chemistry. B, vol. 115, (no. 19), pp. 5886-93, 2011/May/19. | Journal Article
2010
Adsorption of alpha-synuclein on lipid bilayers: modulating the structure and stability of protein assemblies.
Haque, Farzin⋅Pandey, Anjan P⋅Cambrea, Lee R⋅Rochet, Jean Christophe and Hovis, Jennifer S
The journal of physical chemistry. B, vol. 114, (no. 11), pp. 4070-81, 2010/Mar/25. | Journal Article
 
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models.
Su, Linhui Julie⋅Su, Linhui J⋅Auluck, Pavan K⋅Auluck, Pavan K⋅Outeiro, Tiago F⋅Outeiro, Tiago Fleming⋅Yeger-Lotem, Esti⋅Yeger-Lotem, Esti⋅Kritzer, Joshua A⋅Kritzer, Joshua A⋅Tardiff, Daniel F⋅Tardiff, Daniel F⋅Strathearn, Katherine E⋅Strathearn, Katherine E⋅Liu, Fang⋅Liu, Fang⋅Cao, Songsong⋅Cao, Songsong⋅Hamamichi, Shusei⋅Hamamichi, Shusei⋅Hill, Kathryn J⋅Hill, Kathryn J⋅Caldwell, Kim A⋅Caldwell, Kim A⋅Bell, George W⋅Bell, George W⋅Fraenkel, Ernest⋅Fraenkel, Ernest⋅Cooper, Antony A⋅Cooper, Antony A⋅Caldwell, Guy A⋅Caldwell, Guy⋅McCaffery, J M⋅McCaffery, J Michael⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Lindquist, Susan and Lindquist, Susan L
Disease models & mechanisms, vol. 3, (no. 3-4), pp. 194-208, 2010 Mar-Apr. | Journal Article
 
PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease
Zheng, Bin⋅Zheng, Bin⋅Liao, Zhixiang⋅Liao, Zhixiang⋅Locascio, Joseph J⋅Locascio, Joseph J⋅Lesniak, Kristen A⋅Lesniak, Kristen A⋅Roderick, Sarah S⋅Roderick, Sarah S⋅Watt, Marla L⋅Watt, Marla L⋅Eklund, Aron C⋅Eklund, Aron C⋅Zhang-James, Yanli⋅Zhang-James, Yanli⋅Kim, Peter D⋅Kim, Peter D⋅Hauser, Michael A⋅Hauser, Michael A⋅Grünblatt, Edna⋅Grünblatt, Edna⋅Moran, Linda B⋅Moran, Linda B⋅Mandel, Silvia A⋅Mandel, Silvia A⋅Riederer, Peter⋅Riederer, Peter⋅Miller, Renee M⋅Miller, Renee⋅Federoff, Howard J⋅Federoff, Howard J⋅Wüllner, Ullrich⋅Wüllner, Ullrich⋅Papapetropoulos, Spyridon⋅Papapetropoulos, Spyridon⋅Youdim, Moussa B⋅Youdim, Moussa B⋅Cantuti-Castelvetri, Ippolita⋅Cantuti-Castelvetri, Ippolita⋅Young, Anne B⋅Young, Anne B⋅Vance, Jeffery M⋅Vance, Jeffery M⋅Davis, Richard L⋅Davis, Richard L⋅Hedreen, John C⋅Hedreen, John C⋅Adler, Charles H⋅Adler, Charles H⋅Beach, Thomas G⋅Beach, Thomas G⋅Graeber, Manuel B⋅Graeber, Manuel B⋅Middleton, Frank A⋅Middleton, Frank A⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Scherzer, Clemens R and Scherzer, Clemens
Science translational medicine, vol. 2, (no. 52), pp. 52ra73, 2010-Oct-06. | Journal Article
2009
[alpha]-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
Gitler, Aaron⋅Chesi, Alessandra⋅Geddie, Melissa L⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Hill, Kathryn J⋅Caldwell, Kim A⋅Caldwell, Guy⋅Cooper, Antony A⋅Rochet, Jean Christophe and Lindquist, Susan L
Nature Genetics, vol. 41, (no. 3), pp. 308-315, 2009. | Journal Article
 
Alpha-synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity.
Gitler, Aaron D⋅Chesi, Alessandra⋅Geddie, Melissa L⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Hill, Kathryn J⋅Caldwell, Kim A⋅Caldwell, Guy A⋅Cooper, Antony A⋅Rochet, Jean Christophe and Lindquist, Susan
Nature genetics, vol. 41, (no. 3), pp. 308-315, March 2009. | Journal Article
 
Clustering of alpha-synuclein on supported lipid bilayers: role of anionic lipid, protein, and divalent ion concentration.
Pandey, Anjan P⋅Haque, Farzin⋅Rochet, Jean Christophe and Hovis, Jennifer S
Biophysical journal, vol. 96, (no. 2), pp. 540-51, 2009/Jan. | Journal Article
 
Oc-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity
GITLER, Aaron D⋅CHESI, Alessandra⋅LINDQUIST, Susan⋅GEDDIE, Melissa L⋅STRATHEARN, Katherine E⋅HAMAMICHI, Shusei⋅HILL, Kathryn J⋅CALDWELL, Kim A⋅CALDWELL, Guy A⋅COOPER, Antony A and Rochet, Jean Christophe
Nature genetics, vol. 41, (no. 3), pp. 315, 2009. | Journal Article
 
Path dependence of three-phase or two-phase end points in fluid binary lipid mixtures.
Lamberson, Emily R⋅Cambrea, Lee R⋅Rochet, Jean Christophe and Hovis, Jennifer S
The journal of physical chemistry. B, vol. 113, (no. 11), pp. 3431-6, 2009/Mar/19. | Journal Article
2008
Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease
Liu, Fang⋅Nguyen, Jamie L⋅Hulleman, John D⋅Li, Li and Rochet, Jean Christophe
Journal of Neurochemistry, vol. 105, (no. 6), pp. 2435-2453, Jun 2008. | Journal Article
 
Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults.
Liu, Fang⋅Hindupur, Jagadish⋅Nguyen, Jamie L⋅Ruf, Katie J⋅Zhu, Junyi⋅Schieler, Jeremy L⋅Bonham, Connie C⋅Wood, Karl V⋅Davisson, V. J and Rochet, Jean Christophe
Free radical biology & medicine, vol. 45, (no. 3), pp. 242-55, 2008/Aug/1. | Journal Article
 
The Parkinson's disease protein alpha -synuclein disrupts cellular Rab homeostasis
Gitler, Aaron⋅Bevis, Brooke J⋅Shorter, James⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Su, Linhui J⋅Caldwell, Kim A⋅Caldwell, Guy⋅Rochet, Jean Christophe⋅McCaffery, JMichael⋅Barlowe, Charles K and Lindquist, Susan L
Proceedings of the National Academy of Sciences, USA, vol. 105, (no. 1), pp. 145-150, 2008. | Journal Article
 
The Parkinson's disease protein alpha-synuclein disrupts cellular Rab homeostasis.
Gitler, Aaron D⋅Bevis, Brooke J⋅Shorter, James⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Su, Linhui Julie⋅Caldwell, Kim A⋅Caldwell, Guy A⋅Rochet, Jean Christophe⋅McCaffery, J Michael⋅Barlowe, Charles and Lindquist, Susan
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 1), pp. 145-150, January 8, 2008. | Journal Article
 
The Parkinson's disease protein ¿-synuclein disrupts cellular Rab homeostasis
Gitler, Aaron⋅Bevis, Brooke J⋅Shorter, James⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Su, Linhui J⋅Caldwell, Kim A⋅Caldwell, Guy⋅Rochet, Jean Christophe⋅McCaffery, J M⋅Barlowe, Charles K and Lindquist, Susan L
Proceedings of the National Academy of Sciences of the United States of America, vol. 105, (no. 1), Jan 8, 2008. | Journal Article
 
The Parkinson's disease protein α-synuclein disrupts cellular Rab homeostasis.
Gitler, Aaron⋅Bevis, Brooke J⋅Shorter, James⋅Strathearn, Katherine E⋅Hamamichi, Shusei⋅Su, Linhui J⋅Caldwell, Kim A⋅Caldwell, Guy⋅Rochet, Jean Christophe⋅McCaffery, J. M⋅Barlowe, Charles and Lindquist, Susan L
Proceedings of the National Academy of Sciences of the United States of America., vol. 105, (no. 1), pp. 145-150, 2008. | Journal Article
2007
Destabilization of DJ-1 by Familial Substitution and Oxidative Modifications: Implications for Parkinson's Disease
Hulleman, JD⋅Mirzaei, Hamid⋅Guigard, E.⋅Taylor, KL⋅Ray, SS⋅Kay, CM⋅Regnier, Fred E and Rochet, Jean Christophe
Biochemistry (Washington), vol. 46, (no. 19), pp. 5776-5789, 2007. | Journal Article
 
Effect of Ions on the Organization of Phosphatidylcholine/Phosphatidic Acid Bilayers
Cambrea, Lee R⋅Haque, Farzin⋅Schieler, Jeremy L⋅Rochet, Jean Christophe and Hovis, Jennifer S
Biophysical Journal, vol. 93, (no. 5), pp. 1630-8, Sep 1, 2007. | Journal Article
 
Helical [alpha]-synuclein forms highly conductive ion channels
Zakharov, Stanislav⋅Zakharov, Stanislav⋅Hulleman, John⋅Hulleman, John D⋅Dutseva, Elena A⋅Dutseva, Elena⋅Antonenko, Yuri⋅Antonenko, Yuri N⋅Rochet, Jean-Christophe⋅Rochet, Jean Christophe⋅Cramer, William and Cramer, William A
Biochemistry, vol. 46, (no. 50), pp. 14369, 20071218. | Journal Article