21 Publications
2018
Disruption of nNOS–NOS1AP protein–protein interactions suppresses neuropathic pain in mice
Lee, Wan-Hung⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Li, Li-Li⋅Li, Li-Li⋅Li, Li-Li⋅Li, Li-Li⋅Chawla, Aarti⋅Chawla, Aarti⋅Chawla, Aarti⋅Chawla, Aarti⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Courtney, Michael J⋅Courtney, Michael J⋅Courtney, Michael J⋅Courtney, Michael J⋅Hohmann, Andrea G⋅Hohmann, Andrea G⋅Hohmann, Andrea G and Hohmann, Andrea G
Pain, vol. 159, (no. 5), pp. 863, 2018-May. | Journal Article
 
ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability
Lee, Wan-Hung⋅Lee, Wan-Hung⋅Carey, Lawrence M⋅Carey, Lawrence M⋅Li, Li-Li⋅Li, Li-Li⋅Xu, Zhili⋅Xu, Zhili⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Courtney, Michael J⋅Courtney, Michael J⋅Hohmann, Andrea G and Hohmann, Andrea G
Molecular Pain, vol. 14, pp. 1744806918801224, 20180900. | Journal Article
2017
Small molecule inhibitors of PSD95-nNOS protein-protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats
Carey, Lawrence⋅Carey, Lawrence⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Gutierrez, Tannia⋅Gutierrez, Tannia⋅Kulkarni, Pushkar⋅Kulkarni, Pushkar⋅Thakur, Ganesh⋅Thakur, Ganesh⋅Lai, Yvonne⋅Lai, Yvonne⋅Hohmann, Andrea and Hohmann, Andrea
Neuroscience, vol. 349, pp. 317, 2017. | Journal Article
2016
Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein–protein interaction inhibitors
Smith, Alexandra E⋅Smith, Alexandra E⋅Smith, Alexandra E⋅Smith, Alexandra E⋅Xu, Zhili⋅Xu, Zhili⋅Xu, Zhili⋅Xu, Zhili⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Kulkarni, Pushkar M⋅Kulkarni, Pushkar M⋅Kulkarni, Pushkar M⋅Kulkarni, Pushkar M⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Hohmann, Andrea G⋅Hohmann, Andrea G⋅Hohmann, Andrea G⋅Hohmann, Andrea G⋅Crystal, Jonathon D⋅Crystal, Jonathon D⋅Crystal, Jonathon D and Crystal, Jonathon D
Behavioural Brain Research, vol. 305, pp. 29, 2016-05-15. | Journal Article
2015
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
Lee, Wan-Hung⋅Lee, Wan-Hung⋅Lee, Wan-Hung⋅Xu, Zhili⋅Xu, Zhili⋅Xu, Zhili⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Ashpole, Nicole M⋅Hudmon, Andy⋅Hudmon, Andy⋅Hudmon, Andy⋅Kulkarni, Pushkar M⋅Kulkarni, Pushkar M⋅Kulkarni, Pushkar M⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Hohmann, Andrea G⋅Hohmann, Andrea G and Hohmann, Andrea G
Neuropharmacology, vol. 97, pp. 464-475, October 2015. | Journal Article
2014
Prophylactic Cannabinoid Administration Blocks the Development of Paclitaxel-Induced Neuropathic Nociception during Analgesic Treatment and following Cessation of Drug Delivery
Rahn, Elizabeth J⋅Rahn, Elizabeth J⋅Deng, Liting⋅Deng, Liting⋅Thakur, Ganesh A⋅Thakur, Ganesh A⋅Vemuri, Kiran⋅Vemuri, Kiran⋅Zvonok, Alexander M⋅Zvonok, Alexander M⋅Lai, Yvonne Y⋅Lai, Yvonne Y⋅Makriyannis, Alexandros⋅Makriyannis, Alexandros⋅Hohmann, Andrea G and Hohmann, Andrea G
Molecular Pain, vol. 10, (no. 1), pp. 27, 20140418. | Journal Article
2011
LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs.
Lai, Yvonne⋅Adhikarakunnathu, Sreedevi⋅Bhardwaj, Kanchan⋅Ranjith-Kumar, C T⋅Wen, Yahong⋅Jordan, Jarrat L⋅Wu, Linda H⋅Dragnea, Bogdan⋅San Mateo, Lani and Kao, C. C
PloS one, vol. 6, (no. 10), pp. e26632, 2011. | Journal Article
 
Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.
Lai, Yvonne⋅Lai, Yvonne⋅Yi, Guanghui⋅Yi, Guanghui⋅Chen, Alice⋅Chen, Alice⋅Bhardwaj, Kanchan⋅Bhardwaj, Kanchan⋅Tragesser, Brady J⋅Tragesser, Brady J⋅Rodrigo A Valverde⋅Valverde, Rodrigo⋅Zlotnick, Adam⋅Zlotnick, Adam⋅Mukhopadhyay, Suchetana⋅Mukhopadhyay, Suchetana⋅Ranjith-Kumar, C T⋅Ranjith-Kumar, C T⋅Kao, C Cheng and Kao, C. C
PloS one, vol. 6, (no. 10), pp. e25837, 2011. | Journal Article
2010
Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I.
Ranjith-Kumar, C T⋅Lai, Yvonne⋅Sarisky, Robert T and Cheng Kao, C
PloS one, vol. 5, (no. 9), pp. e12878, 2010. | Journal Article
2009
Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents.
Florio, S K⋅Loh, C⋅Huang, S M⋅Iwamaye, A E⋅Kitto, Kelley F⋅Fowler, K W⋅Treiberg, J A⋅Hayflick, J S⋅Walker, J M⋅Fairbanks, Carolyn A and Lai, Yvonne
British journal of pharmacology, vol. 158, (no. 2), pp. 494-506, 2009/Sep. | Journal Article
1998
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region.
Kashishian, A⋅Howard, M⋅Loh, C⋅Gallatin, W M⋅Hoekstra, M F and Lai, Yvonne
The Journal of biological chemistry, vol. 273, (no. 42), pp. 27412-9, 1998/Oct/16. | Journal Article
1996
Cloning, expression, and comparison of the binding characteristics of the known human dopamine receptors.
Hill, P⋅Lai, Yvonne⋅Hnilo, J⋅Lin, C C⋅Karla, M⋅Bounds, S⋅Herz, J and Mitchell, R
Advances in neurology, vol. 69, pp. 41-52, 1996. | Journal Article
1995
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.
Mackie, Kenneth P⋅Lai, Yvonne⋅Westenbroek, R and Mitchell, R
The Journal of Neuroscience, vol. 15, (no. 10), pp. 6552-61, 1995/Oct. | Journal Article
1994
Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle
Marty, I.⋅Robert, M.⋅Villaz, M.⋅De Jongh, KS⋅Lai, Yvonne⋅Catterall, William and Ronjat, M.
Proceedings of the National Academy of Sciences, USA, vol. 91, (no. 6), pp. 2270-2274, 1994. | Journal Article
1993
Selective dephosphorylation of the subunits of skeletal muscle calcium channels by purified phosphoprotein phosphatases.
Lai, Yvonne⋅Peterson, Blaise Z and Catterall, William
Journal of Neurochemistry, vol. 61, (no. 4), pp. 1333-9, 1993/Oct. | Journal Article
 
Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase.
Rotman, EI⋅De Jongh, KS⋅Florio, V.⋅Lai, Yvonne and Catterall, William
Journal of Biological Chemistry, vol. 267, (no. 23), pp. 16100-16105, 1993. | Journal Article
1992
Functional modulation of brain sodium channels by cAMP-dependent phosphorylation.
Li, Ming M⋅West, J W⋅Lai, Yvonne⋅Scheuer, Todd and Catterall, William
Neuron, vol. 8, (no. 6), pp. 1151-9, 1992/Jun. | Journal Article
1990
Cyclic AMP-dependent phosphorylation of two size forms of alpha 1 subunits of L-type calcium channels in rat skeletal muscle cells.
Lai, Yvonne⋅Seagar, M J⋅Takahashi, M and Catterall, William
The Journal of biological chemistry, vol. 265, (no. 34), pp. 20839-48, 1990/Dec/5. | Journal Article
1987
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Lai, Y⋅Nairn, Angus C⋅Gorelick, Fred S and Greengard, Paul
Proceedings of the National Academy of Sciences of the United States of America, vol. 84, (no. 16), pp. 5710-4, 1987/Aug. | Journal Article
1985
Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.
McGuinness, T L⋅Lai, Y and Greengard, P
The Journal of biological chemistry, vol. 260, (no. 3), pp. 1696-1704, February 10, 1985. | Journal Article
1983
A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase.
McGuinness, TL⋅Lai, Yvonne⋅Greengard, Paul⋅Woodgett, J. R and Cohen, P.
FEBS Letters, vol. 163, (no. 2), pp. 329-334, 1983. | Journal Article