21 Publications
2018
Disruption of nNOS–NOS1AP protein–protein interactions suppresses neuropathic pain in mice
Lee, Wan-HungLee, Wan-HungLee, Wan-HungLi, Li-LiLi, Li-LiLi, Li-LiChawla, AartiChawla, AartiChawla, AartiHudmon, AndyHudmon, AndyHudmon, AndyLai, Yvonne YLai, Yvonne YLai, Yvonne YCourtney, Michael JCourtney, Michael JCourtney, Michael JHohmann, Andrea GHohmann, Andrea G and Hohmann, Andrea G
Pain, vol. 159, (no. 5), pp. 863, 2018-May. | Journal Article
 
ZLc002, a putative small-molecule inhibitor of nNOS interaction with NOS1AP, suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with paclitaxel to reduce tumor cell viability
Lee, Wan-HungLee, Wan-HungCarey, Lawrence MCarey, Lawrence MLi, Li-LiLi, Li-LiXu, ZhiliXu, ZhiliLai, Yvonne YLai, Yvonne YCourtney, Michael JCourtney, Michael JHohmann, Andrea G and Hohmann, Andrea G
Molecular Pain, vol. 14, pp. 1744806918801224, 20180900. | Journal Article
2017
Small molecule inhibitors of PSD95-nNOS protein-protein interactions suppress formalin-evoked Fos protein expression and nociceptive behavior in rats
Carey, LawrenceCarey, LawrenceLee, Wan-HungLee, Wan-HungGutierrez, TanniaGutierrez, TanniaKulkarni, PushkarKulkarni, PushkarThakur, GaneshThakur, GaneshLai, YvonneLai, YvonneHohmann, Andrea and Hohmann, Andrea
Neuroscience, vol. 349, pp. 317, 2017. | Journal Article
2016
Source memory in rats is impaired by an NMDA receptor antagonist but not by PSD95-nNOS protein–protein interaction inhibitors
Smith, Alexandra ESmith, Alexandra ESmith, Alexandra ESmith, Alexandra EXu, ZhiliXu, ZhiliXu, ZhiliXu, ZhiliLai, Yvonne YLai, Yvonne YLai, Yvonne YLai, Yvonne YKulkarni, Pushkar MKulkarni, Pushkar MKulkarni, Pushkar MKulkarni, Pushkar MThakur, Ganesh AThakur, Ganesh AThakur, Ganesh AThakur, Ganesh AHohmann, Andrea GHohmann, Andrea GHohmann, Andrea GHohmann, Andrea GCrystal, Jonathon DCrystal, Jonathon DCrystal, Jonathon D and Crystal, Jonathon D
Behavioural Brain Research, vol. 305, pp. 29, 2016-05-15. | Journal Article
2015
Small molecule inhibitors of PSD95-nNOS protein-protein interactions as novel analgesics.
Lee, Wan-HungLee, Wan-HungLee, Wan-HungXu, ZhiliXu, ZhiliXu, ZhiliAshpole, Nicole MAshpole, Nicole MAshpole, Nicole MHudmon, AndyHudmon, AndyHudmon, AndyKulkarni, Pushkar MKulkarni, Pushkar MKulkarni, Pushkar MThakur, Ganesh AThakur, Ganesh AThakur, Ganesh ALai, Yvonne YLai, Yvonne YLai, Yvonne YHohmann, Andrea GHohmann, Andrea G and Hohmann, Andrea G
Neuropharmacology, vol. 97, pp. 464-475, October 2015. | Journal Article
2014
Prophylactic Cannabinoid Administration Blocks the Development of Paclitaxel-Induced Neuropathic Nociception during Analgesic Treatment and following Cessation of Drug Delivery
Rahn, Elizabeth JRahn, Elizabeth JDeng, LitingDeng, LitingThakur, Ganesh AThakur, Ganesh AVemuri, KiranVemuri, KiranZvonok, Alexander MZvonok, Alexander MLai, Yvonne YLai, Yvonne YMakriyannis, AlexandrosMakriyannis, AlexandrosHohmann, Andrea G and Hohmann, Andrea G
Molecular Pain, vol. 10, (no. 1), pp. 27, 20140418. | Journal Article
2011
LL37 and cationic peptides enhance TLR3 signaling by viral double-stranded RNAs.
Lai, YvonneAdhikarakunnathu, SreedeviBhardwaj, KanchanRanjith-Kumar, C TWen, YahongJordan, Jarrat LWu, Linda HDragnea, BogdanSan Mateo, Lani and Kao, C. C
PloS one, vol. 6, (no. 10), pp. e26632, 2011. | Journal Article
 
Viral double-strand RNA-binding proteins can enhance innate immune signaling by toll-like Receptor 3.
Lai, YvonneLai, YvonneYi, GuanghuiYi, GuanghuiChen, AliceChen, AliceBhardwaj, KanchanBhardwaj, KanchanTragesser, Brady JTragesser, Brady JValverde, RodrigoRodrigo A ValverdeZlotnick, AdamZlotnick, AdamMukhopadhyay, SuchetanaMukhopadhyay, SuchetanaRanjith-Kumar, C TRanjith-Kumar, C TKao, C. C and Kao, C Cheng
PloS one, vol. 6, (no. 10), pp. e25837, 2011. | Journal Article
2010
Green tea catechin, epigallocatechin gallate, suppresses signaling by the dsRNA innate immune receptor RIG-I.
Ranjith-Kumar, C TLai, YvonneSarisky, Robert T and Cheng Kao, C
PloS one, vol. 5, (no. 9), pp. e12878, 2010. | Journal Article
2009
Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents.
Florio, S KLoh, CHuang, S MIwamaye, A EKitto, Kelley FFowler, K WTreiberg, J AHayflick, J SWalker, J MFairbanks, Carolyn A and Lai, Yvonne
British journal of pharmacology, vol. 158, (no. 2), pp. 494-506, 2009/Sep. | Journal Article
1998
AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region.
Kashishian, AHoward, MLoh, CGallatin, W MHoekstra, M F and Lai, Yvonne
The Journal of biological chemistry, vol. 273, (no. 42), pp. 27412-9, 1998/Oct/16. | Journal Article
1996
Cloning, expression, and comparison of the binding characteristics of the known human dopamine receptors.
Hill, PLai, YvonneHnilo, JLin, C CKarla, MBounds, SHerz, J and Mitchell, R
Advances in neurology, vol. 69, pp. 41-52, 1996. | Journal Article
1995
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor.
Mackie, Kenneth PLai, YvonneWestenbroek, R and Mitchell, R
The Journal of Neuroscience, vol. 15, (no. 10), pp. 6552-61, 1995/Oct. | Journal Article
1994
Biochemical evidence for a complex involving dihydropyridine receptor and ryanodine receptor in triad junctions of skeletal muscle
Marty, I.Robert, M.Villaz, M.De Jongh, KSLai, YvonneCatterall, William and Ronjat, M.
Proceedings of the National Academy of Sciences, USA, vol. 91, (no. 6), pp. 2270-2274, 1994. | Journal Article
1993
Selective dephosphorylation of the subunits of skeletal muscle calcium channels by purified phosphoprotein phosphatases.
Lai, YvonnePeterson, Blaise Z and Catterall, William
Journal of Neurochemistry, vol. 61, (no. 4), pp. 1333-9, 1993/Oct. | Journal Article
 
Specific phosphorylation of a COOH-terminal site on the full-length form of the alpha 1 subunit of the skeletal muscle calcium channel by cAMP-dependent protein kinase.
Rotman, EIDe Jongh, KSFlorio, V.Lai, Yvonne and Catterall, William
Journal of Biological Chemistry, vol. 267, (no. 23), pp. 16100-16105, 1993. | Journal Article
1992
Functional modulation of brain sodium channels by cAMP-dependent phosphorylation.
Li, Ming MWest, J WLai, YvonneScheuer, Todd and Catterall, William
Neuron, vol. 8, (no. 6), pp. 1151-9, 1992/Jun. | Journal Article
1990
Cyclic AMP-dependent phosphorylation of two size forms of alpha 1 subunits of L-type calcium channels in rat skeletal muscle cells.
Lai, YvonneSeagar, M JTakahashi, M and Catterall, William
The Journal of biological chemistry, vol. 265, (no. 34), pp. 20839-48, 1990/Dec/5. | Journal Article
1987
Ca2+/calmodulin-dependent protein kinase II: identification of autophosphorylation sites responsible for generation of Ca2+/calmodulin-independence.
Lai, YNairn, Angus CGorelick, Fred S and Greengard, Paul
Proceedings of the National Academy of Sciences of the United States of America, vol. 84, (no. 16), pp. 5710-4, 1987/Aug. | Journal Article
1985
Ca2+/calmodulin-dependent protein kinase II. Isozymic forms from rat forebrain and cerebellum.
McGuinness, T LLai, Y and Greengard, P
The Journal of biological chemistry, vol. 260, (no. 3), pp. 1696-1704, February 10, 1985. | Journal Article
1983
A multifunctional calmodulin-dependent protein kinase. Similarities between skeletal muscle glycogen synthase kinase and a brain synapsin I kinase.
McGuinness, TLLai, YvonneGreengard, PaulWoodgett, J. R and Cohen, P.
FEBS Letters, vol. 163, (no. 2), pp. 329-334, 1983. | Journal Article