100 Publications (Page 1 of 4)
2020
Glycolysis, via NADH-dependent dimerisation of CtBPs, regulates hypoxia-induced expression of CAIX and stem-like breast cancer cell survival.
Kreuzer, MiraBanerjee, ArindamBirts, Charles NDarley, MatthewTavassoli, AliIvan, Mircea and Blaydes, Jeremy P
FEBS letters, July 3, 2020. | Journal Article
 
HypoxamiR-210 accelerates wound healing in diabetic mice by improving cellular metabolism.
Narayanan, SampathEliasson Angelstig, SofieXu, ChengGrünler, JacobZhao, AllanZhu, WanXu Landén, NingStåhle, MonaZhang, JingpingIvan, MirceaMaltesen, Raluca GeorgianaBotusan, Ileana RuxandraRajamand Ekberg, NedaZheng, Xiaowei and Catrina, Sergiu-Bogdan
Communications biology, vol. 3, (no. 1), pp. 768, December 14, 2020. | Journal Article
 
Osteocytic miR21 deficiency improves bone strength independent of sex despite having sex divergent effects on osteocyte viability and bone turnover
Davis, Hannah MDavis, Hannah MDavis, Hannah MDavis, Hannah MDeosthale, Padmini JDeosthale, Padmini JDeosthale, Padmini JDeosthale, Padmini JPacheco‐Costa, RafaelPacheco‐Costa, RafaelPacheco‐Costa, RafaelPacheco‐Costa, RafaelEssex, Alyson LEssex, Alyson LEssex, Alyson LEssex, Alyson LAtkinson, Emily GAtkinson, Emily GAtkinson, Emily GAtkinson, Emily GAref, Mohammad WAref, Mohammad WAref, Mohammad WAref, Mohammad WDilley, Julian EDilley, Julian EDilley, Julian EDilley, Julian EBellido, TeresitaBellido, TeresitaBellido, TeresitaBellido, TeresitaIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaAllen, Matthew RAllen, Matthew RAllen, Matthew RAllen, Matthew RPlotkin, Lilian IPlotkin, Lilian IPlotkin, Lilian I and Plotkin, Lilian I
The FEBS Journal, vol. 287, (no. 5), pp. 963, March 2020. | Journal Article
 
Transcriptomic modifications in developmental cardiopulmonary adaptations to chronic hypoxia using a murine model of simulated high-altitude exposure.
Krishnan, SheilaKrishnan, SheilaStearman, Robert SStearman, Robert SZeng, LilyZeng, LilyFisher, AmandaFisher, AmandaMickler, Elizabeth AMickler, Elizabeth ARodriguez, Brooke HRodriguez, Brooke HSimpson, Edward RSimpson, Edward RCook, ToddCook, ToddSlaven, James ESlaven, James EIvan, MirceaIvan, MirceaGeraci, Mark WGeraci, Mark WLahm, TimLahm, TimTepper, Robert S and Tepper, Robert S
American journal of physiology. Lung cellular and molecular physiology, vol. 319, (no. 3), pp. L456-L470, September 1, 2020. | Journal Article
2019
Profiling molecular regulators of recurrence in chemorefractory triple-negative breast cancers
Hancock, Bradley AHancock, Bradley AHancock, Bradley AHancock, Bradley AHancock, Bradley AHancock, Bradley AChen, Yu-HsiangChen, Yu-HsiangChen, Yu-HsiangChen, Yu-HsiangChen, Yu-HsiangChen, Yu-HsiangSolzak, Jeffrey PSolzak, Jeffrey PSolzak, Jeffrey PSolzak, Jeffrey PSolzak, Jeffrey PSolzak, Jeffrey PAhmad, Mufti NAhmad, Mufti NAhmad, Mufti NAhmad, Mufti NAhmad, Mufti NAhmad, Mufti NWedge, David CWedge, David CWedge, David CWedge, David CWedge, David CWedge, David CBrinza, DumitruBrinza, DumitruBrinza, DumitruBrinza, DumitruBrinza, DumitruBrinza, DumitruScafe, CharlesScafe, CharlesScafe, CharlesScafe, CharlesScafe, CharlesScafe, CharlesVeitch, JamesVeitch, JamesVeitch, JamesVeitch, JamesVeitch, JamesVeitch, JamesGottimukkala, RajeshGottimukkala, RajeshGottimukkala, RajeshGottimukkala, RajeshGottimukkala, RajeshGottimukkala, RajeshShort, WaltShort, WaltShort, WaltShort, WaltShort, WaltShort, WaltAtale, Rutuja VAtale, Rutuja VAtale, Rutuja VAtale, Rutuja VAtale, Rutuja VAtale, Rutuja VIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaBadve, Sunil SBadve, Sunil SBadve, Sunil SBadve, Sunil SBadve, Sunil SBadve, Sunil SSchneider, Bryan PSchneider, Bryan PSchneider, Bryan PSchneider, Bryan PSchneider, Bryan PSchneider, Bryan PLu, XiongbinLu, XiongbinLu, XiongbinLu, XiongbinLu, XiongbinLu, XiongbinMiller, Kathy DMiller, Kathy DMiller, Kathy DMiller, Kathy DMiller, Kathy DMiller, Kathy DRadovich, MilanRadovich, MilanRadovich, MilanRadovich, MilanRadovich, Milan and Radovich, Milan
Breast cancer research : BCR, vol. 21, (no. 1), pp. 87, 2019-08-05. | Journal Article
 
The nuclear hypoxia-regulated NLUCAT1 long non-coding RNA contributes to an aggressive phenotype in lung adenocarcinoma through regulation of oxidative stress
Moreno Leon, LauraGautier, MarineGautier, MarineAllan, RichardAllan, RichardIlié, MariusIlié, MariusNottet, NicolasNottet, NicolasPons, NicolasPons, NicolasPaquet, AgnesPaquet, AgnesLebrigand, KévinLebrigand, KévinTruchi, MarinFassy, JulienFassy, JulienMagnone, VirginieMagnone, VirginieKinnebrew, GarrettRadovich, MilanRadovich, MilanCheok, Meyling Hua-ChenBarbry, PascalBarbry, PascalVassaux, GeorgesVassaux, GeorgesMarquette, Charles-HugoPonzio, GillesPonzio, GillesIvan, MirceaPottier, NicolasPottier, NicolasHofman, PaulHofman, PaulBernard, MariMari, BernardRezzonico, Roger and Rezzonico, Roger
Oncogene, vol. 38, (no. 46), pp. 7165, 2019-11-00. | Journal Article
2018
Abstract 2427: Targeting intracellular pH regulation as a novel approach to overcome hypoxia-mediated drug resistance in FLT3/ITD mutated AML
Chen, FangliChen, FangliChen, FangliRogozea, Adriana LRogozea, Adriana LRogozea, Adriana LWu, XueWu, XueWu, XueSandusky, GeorgeSandusky, GeorgeSandusky, GeorgeIvan, MirceaIvan, MirceaIvan, MirceaKonig, HeikoKonig, Heiko and Konig, Heiko
Cancer Research, vol. 78, (no. 13 Supplement), pp. 2427, 2018-07-01. | Journal Article
 
Enteral Arg-Gln Dipeptide Administration Increases Retinal Docosahexaenoic Acid and Neuroprotectin D1 in a Murine Model of Retinopathy of Prematurity
Shaw, Lynn CalvinLi Calzi, SergioLi, NanMoldovan, LeniSengupta-Caballero, NilanjanaQuigley, Judith LindseyIvan, MirceaJun, BokkyooBazan, Nicolas GBoulton, Michael EdwinBusik, JuliaNeu, Josef and Grant, Maria B
Investigative ophthalmology & visual science, vol. 59, (no. 2), pp. 869, 2018-02-01. | Journal Article
 
Genoproteomic analysis of leukemic cell response to Cytarabine reveals synergistic opportunities centered on cholesterol metabolism
Farmer, AlexFarmer, AlexChen, FangliChen, FangliWu, XueWu, XueRogozea, AdrianaRogozea, AdrianaIvan, MirceaIvan, MirceaKonig, Heiko and Konig, Heiko
Proceedings of IMPRS, vol. 1, (no. 1), 2018-12-07. | Journal Article
 
Integrative Analysis of AML Cell Response to Cytarabine Reveals Synergistic Opportunities Centered on Cholesterol Metabolism
Chen, FangliChen, FangliWu, XueWu, XueAdriana, RogozeaAdriana, RogozeaGuo, BinGuo, BinBoswell, H. ScottBoswell, H. ScottCalin, George ACalin, George AIvan, MirceaIvan, MirceaKonig, Heiko and Konig, Heiko
Blood, vol. 132, (no. Supplement 1), pp. 2631, 2018-11-29. | Journal Article
 
P38α/JNK signaling restrains erythropoiesis by suppressing Ezh2-mediated epigenetic silencing of Bim
Hu, PingNebreda, Angel RHanenberg, HelmutKinnebrew, Garrett HIvan, MirceaYoder, Mervin CFilippi, Marie-DominiqueBroxmeyer, Hal E and Kapur, Reuben
Nature communications, vol. 9, (no. 1), pp. 15, 2018-08-29. | Journal Article
 
P38α/JNK Signaling Restrains Erythropoiesis By Suppressing Ezh2-Mediated Epigenetic Silencing of Bim
Hu, PingHu, PingNebreda, AngelNebreda, AngelHanenberg, HelmutHanenberg, HelmutKinnebrew, GarrettKinnebrew, GarrettIvan, MirceaIvan, MirceaYoder, Mervin CYoder, Mervin CFilippi, Marie-DominiqueFilippi, Marie-DominiqueBroxmeyer, Hal EBroxmeyer, Hal EKapur, Reuben and Kapur, Reuben
Blood, vol. 132, (no. Supplement 1), pp. 3837, 2018-11-29. | Journal Article
 
The Many Faces of Long Noncoding RNAs in Cancer
Wu, XueWu, XueTudoran, Oana MTudoran, Oana MCalin, George ACalin, George AIvan, Mircea and Ivan, Mircea
Antioxidants & Redox Signalling, vol. 29, (no. 9), pp. 922-935, Sep 20, 2018. | Journal Article
2017
Abstract 1998: Transcriptome analysis of hypoxic head and neck cancer cells uncovers intron retention in EIF2B5 as a mechanism to reduce protein synthesis
Brady, Lauren KBrady, Lauren KWang, HejiaWang, HejiaRadens, CalebRadens, CalebRadovich, MilanRadovich, MilanMaity, AmitMaity, AmitIvan, CristinaIvan, CristinaIvan, MirceaIvan, MirceaBarash, YosephBarash, YosephKoumenis, Constantinos and Koumenis, Constantinos
Cancer Research, vol. 77, (no. 13 Supplement), pp. 1998, 2017-07-01. | Journal Article
 
Abstract 4512: The landscape of hypoxia-driven alternative splicing in breast cancer
Choudhry, HaniOikonomopoulos, SpyridonYu, PengIvan, CristinaIvan, MirceaHarris, Adrian L and Ragoussis, Jiannis
Cancer Research, vol. 77, (no. 13 Supplement), pp. 4512, 2017-07-01. | Journal Article
 
Declined Presentation Inhibition of carbonic anhydrase IX as a novel strategy to target FLT3/ITD mutated aml cells under hypoxic conditions
Konig, HeikoKonig, HeikoChen, FangliChen, FangliRogozea, AdrianaRogozea, AdrianaKinnebrew, GarrettKinnebrew, GarrettIvan, Mircea and Ivan, Mircea
Experimental Hematology, vol. 53, pp. S88, September 2017. | Journal Article
 
Disruption of the Cx43/miR21 pathway leads to osteocyte apoptosis and increased osteoclastogenesis with aging.
Davis, Hannah MDavis, Hannah MDavis, Hannah MDavis, Hannah MPacheco‐Costa, RafaelPacheco-Costa, RafaelPacheco‐Costa, RafaelPacheco‐Costa, RafaelAtkinson, Emily GAtkinson, Emily GAtkinson, Emily GAtkinson, Emily GBrun, Lucas RBrun, Lucas RBrun, Lucas RBrun, Lucas RGortazar, Arancha RGortazar, Arancha RGortazar, Arancha RGortazar, Arancha RHarris, JuliaHarris, JuliaHarris, JuliaHarris, JuliaHiasa, MasahiroHiasa, MasahiroHiasa, MasahiroHiasa, MasahiroBolarinwa, Surajudeen ABolarinwa, Surajudeen ABolarinwa, Surajudeen ABolarinwa, Surajudeen AYoneda, ToshiyukiYoneda, ToshiyukiYoneda, ToshiyukiYoneda, ToshiyukiIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBruzzaniti, AngelaBellido, TeresitaBellido, TeresitaBellido, TeresitaBellido, TeresitaPlotkin, Lilian IPlotkin, Lilian IPlotkin, Lilian I and Plotkin, Lilian I
Aging cell, vol. 16, (no. 3), pp. 551-563, June 2017. | Journal Article
 
Erythropoietin stimulates murine and human fibroblast growth factor-23, revealing novel roles for bone and bone marrow
Clinkenbeard, Erica LClinkenbeard, Erica LClinkenbeard, Erica LClinkenbeard, Erica LClinkenbeard, Erica LClinkenbeard, Erica LHanudel, Mark RHanudel, Mark RHanudel, Mark RHanudel, Mark RHanudel, Mark RHanudel, Mark RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RStayrook, Keith RAppaiah, Hitesh NidumandaAppaiah, Hitesh NidumandaAppaiah, Hitesh NidumandaAppaiah, Hitesh NidumandaAppaiah, Hitesh NidumandaAppaiah, Hitesh NidumandaFarrow, Emily GFarrow, Emily GFarrow, Emily GFarrow, Emily GFarrow, Emily GFarrow, Emily GCass, Taryn ACass, Taryn ACass, Taryn ACass, Taryn ACass, Taryn ACass, Taryn ASummers, Lelia JSummers, Lelia JSummers, Lelia JSummers, Lelia JSummers, Lelia JSummers, Lelia JIp, Colin SIp, Colin SIp, Colin SIp, Colin SIp, Colin SIp, Colin SHum, Julia MHum, Julia MHum, Julia MHum, Julia MHum, Julia MHum, Julia MThomas, Joseph CThomas, Joseph CThomas, Joseph CThomas, Joseph CThomas, Joseph CThomas, Joseph CIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaRichine, Briana MRichine, Briana MRichine, Briana MRichine, Briana MRichine, Briana MRichine, Briana MChan, Rebecca JChan, Rebecca JChan, Rebecca JChan, Rebecca JChan, Rebecca JChan, Rebecca JClemens, Thomas LClemens, Thomas LClemens, Thomas LClemens, Thomas LClemens, Thomas LClemens, Thomas LSchipani, ErnestinaSchipani, ErnestinaSchipani, ErnestinaSchipani, ErnestinaSchipani, ErnestinaSchipani, ErnestinaSabbagh, YvesSabbagh, YvesSabbagh, YvesSabbagh, YvesSabbagh, YvesSabbagh, YvesXu, LinlinXu, LinlinXu, LinlinXu, LinlinXu, LinlinXu, LinlinSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FSrour, Edward FAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BAlvarez, Marta BKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa AKacena, Melissa ASalusky, Isidro BSalusky, Isidro BSalusky, Isidro BSalusky, Isidro BSalusky, Isidro BSalusky, Isidro BGanz, TomasGanz, TomasGanz, TomasGanz, TomasGanz, TomasGanz, TomasNemeth, ElizabetaNemeth, ElizabetaNemeth, ElizabetaNemeth, ElizabetaNemeth, ElizabetaNemeth, ElizabetaWhite, Kenneth EWhite, Kenneth EWhite, Kenneth EWhite, Kenneth EWhite, Kenneth E and White, Kenneth E
Haematologica, vol. 102, (no. 11), pp. e430, 2017-11-00. | Journal Article
 
On a new sequence of positive linear operators related to squared Bernstein polynomials
Gavrea, IoanGavrea, IoanIvan, Mircea and Ivan, Mircea
Positivity, vol. 21, (no. 3), pp. 917, 20170900. | Journal Article
 
The EGLN-HIF O2-Sensing System: Multiple Inputs and Feedbacks.
Ivan, Mircea and Kaelin, William G
Molecular cell, vol. 66, (no. 6), pp. 772-779, June 15, 2017. | Journal Article
 
The role of MicroRNA molecules and MicroRNA-regulating machinery in the pathogenesis and progression of epithelial ovarian cancer
Wang, XiyinWang, XiyinIvan, MirceaIvan, MirceaHawkins, Shannon M and Hawkins, Shannon M
Gynecologic Oncology, vol. 147, (no. 2), pp. 487, November 2017. | Journal Article
 
Transcriptome analysis of hypoxic cancer cells uncovers intron retention in EIF2B5 as a mechanism to inhibit translation
Brady, Lauren KBrady, Lauren KBrady, Lauren KWang, HejiaWang, HejiaWang, HejiaRadens, Caleb MRadens, Caleb MRadens, Caleb MBi, YueBi, YueBi, YueRadovich, MilanRadovich, MilanRadovich, MilanMaity, AmitMaity, AmitMaity, AmitIvan, CristinaIvan, CristinaIvan, CristinaIvan, MirceaIvan, MirceaIvan, MirceaBarash, YosephBarash, YosephBarash, YosephKoumenis, ConstantinosKoumenis, Constantinos and Koumenis, Constantinos
PLoS biology, vol. 15, (no. 9), pp. e2002623, 2017-Sep. | Journal Article
2016
Abstract 2619: Novel biomarkers and molecular alterations for breast cancer initiation and susceptibility
Marino, NatasciaMarino, NatasciaMarino, NatasciaMarino, NatasciaJohnson, Mariah LJohnson, Mariah LJohnson, Mariah LJohnson, Mariah LTanaka, HiromiTanaka, HiromiTanaka, HiromiTanaka, HiromiWu, XiWu, XiWu, XiWu, XiMathieson, TheresaMathieson, TheresaMathieson, TheresaMathieson, TheresaHenry, Jill EHenry, Jill EHenry, Jill EHenry, Jill EIvan, MirceaIvan, MirceaIvan, MirceaIvan, MirceaLiu, YunlongLiu, YunlongLiu, YunlongLiu, YunlongRufenbarger, ConnieRufenbarger, ConnieRufenbarger, ConnieRufenbarger, ConnieStorniolo, Anna Maria VStorniolo, Anna Maria VStorniolo, Anna Maria V and Storniolo, Anna Maria V
Cancer Research, vol. 76, (no. 14 Supplement), pp. 2619, 2016-07-15. | Journal Article
 
Abstract 4740: Targeting Ref-1/APE1 pathway inhibition in pancreatic cancer using APX3330 for clinical trials
Fishel, Melissa LFishel, Melissa LFishel, Melissa LLogsdon, Derek PLogsdon, Derek PLogsdon, Derek PGrimard, Michelle LGrimard, Michelle LGrimard, Michelle LSupuran, Claudiu TSupuran, Claudiu TSupuran, Claudiu TZyromski, NicholasZyromski, NicholasZyromski, NicholasIvan, MirceaIvan, MirceaIvan, MirceaKelley, Mark RKelley, Mark RKelley, Mark RShah, FenilShah, Fenil and Shah, Fenil
Cancer Research, vol. 76, (no. 14 Supplement), pp. 4740, 2016-07-15. | Journal Article
 
Abstract 733: Analysis of the hypoxic transcriptome in cells and solid tumors reveals a novel spliced isoform of the key regulator of mRNA translation, eIF2B5
Brady, Lauren KBrady, Lauren KShekher, RohilShekher, RohilPopov, VladimirPopov, VladimirIvan, MirceaIvan, MirceaRadovich, MilanRadovich, MilanKoumenis, Constantinos and Koumenis, Constantinos
Cancer Research, vol. 76, (no. 14 Supplement), pp. 733, 2016-07-15. | Journal Article