160 Publications (Page 3 of 7)
2012
Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels
Lee, C Y⋅Lee, C Y Daniel⋅Tse, Wayne⋅Tse, Wayne⋅Smith, Jonathan D⋅Smith, Jonathan D⋅Landreth, Gary E and Landreth, Gary E
The Journal of biological chemistry, vol. 287, (no. 3), pp. 2044, 2012-Jan-13. | Journal Article
 
Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes
Pucilowska, Joanna⋅Pucilowska, Joanna⋅Puzerey, Pavel A⋅Puzerey, Pavel A⋅Karlo, J Colleen⋅Karlo, J C⋅Galán, Roberto F⋅Galán, Roberto F⋅Landreth, Gary E and Landreth, Gary E
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 32, (no. 25), pp. 8677, 2012-Jun-20. | Journal Article
 
FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation
Kyono, Ai⋅Kyono, Ai⋅Kyono, Ai⋅Avishai, Nanthawan⋅Avishai, Nanthawan⋅Avishai, Nanthawan⋅Ouyang, Zhufeng⋅Ouyang, Zhufeng⋅Ouyang, Zhufeng⋅Landreth, Gary E⋅Landreth, Gary⋅Landreth, Gary⋅Murakami, Shunichi⋅Murakami, Shunichi and Murakami, Shunichi
Journal of Bone and Mineral Metabolism, vol. 30, (no. 1), pp. 30, 20120100. | Journal Article
 
Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease
Wilkinson, Brandy L⋅Wilkinson, Brandy⋅Cramer, Paige⋅Cramer, Paige E⋅Varvel, Nicholas⋅Varvel, Nicholas H⋅Reed-Geaghan, Erin⋅Reed-Geaghan, Erin⋅Jiang, Qingguang⋅Jiang, Qingguang⋅Szabo, Alison⋅Szabo, Alison⋅Herrup, Karl⋅Herrup, Karl⋅Lamb, Bruce⋅Lamb, Bruce⋅Landreth, Gary E and Landreth, Gary
Neurobiology of Aging, vol. 33, (no. 1), pp. 197.e32, 2012. | Journal Article
 
Loss of Interleukin Receptor-Associated Kinase 4 Signaling Suppresses Amyloid Pathology and Alters Microglial Phenotype in a Mouse Model of Alzheimer's Disease
Cameron, Brent⋅Cameron, Brent⋅Tse, Wayne⋅Tse, Wayne⋅Lamb, Raza⋅Lamb, Raza⋅Li, Xiaoxia⋅Li, Xiaoxia⋅Lamb, Bruce T⋅Lamb, Bruce T⋅Landreth, Gary E and Landreth, Gary E
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 32, (no. 43), pp. 15123, 2012-Oct-24. | Journal Article
 
Mechanisms underlying the rapid peroxisome proliferator-activated receptor-γ-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease
Mandrekar-Colucci, Shweta⋅Mandrekar-Colucci, Shweta⋅Karlo, J C⋅Karlo, J Colleen⋅Landreth, Gary E and Landreth, Gary E
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 32, (no. 30), pp. 10128, 2012-Jul-25. | Journal Article
2011
A Randomized Pilot Clinical Trial of the Safety of Pioglitazone in Treatment of Patients With Alzheimer Disease
Geldmacher, David S⋅Geldmacher, David S⋅Fritsch, Thomas⋅Fritsch, Thomas⋅McClendon, McKee J⋅McClendon, McKee J⋅Landreth, Gary E and Landreth, Gary
Archives of Neurology, vol. 68, (no. 1), pp. 50, 2011-01-10. | Journal Article
 
Nuclear receptors as therapeutic targets for Alzheimer's disease
Mandrekar-Colucci, Shweta and Landreth, Gary E
Expert Opinion on Therapeutic Targets, vol. 15, (no. 9), pp. 1085-1097, 2011. | Journal Article
 
Sensory network dysfunction, behavioral impairments, and their reversibility in an Alzheimer's β-amyloidosis mouse model
Wesson, Daniel W⋅Wesson, Daniel W⋅Borkowski, Anne H⋅Borkowski, Anne H⋅Landreth, Gary E⋅Landreth, Gary E⋅Nixon, Ralph A⋅Nixon, Ralph A⋅Levy, Efrat⋅Levy, Efrat⋅Wilson, Donald A and Wilson, Donald A
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 31, (no. 44), pp. 15971, 2011-Nov-02. | Journal Article
 
Specific Functions for ERK/MAPK Signaling during PNS Development
Newbern, Jason M⋅Newbern, Jason M⋅Li, Xiaoyan⋅Li, Xiaoyan⋅Shoemaker, Sarah E⋅Shoemaker, Sarah E⋅Zhou, Jiang⋅Zhou, Jiang⋅Zhong, Jian⋅Zhong, Jian⋅Wu, Yaohong⋅Wu, Yaohong⋅Bonder, Daniel⋅Bonder, Daniel⋅Hollenback, Steven⋅Hollenback, Steven⋅Coppola, Giovanni⋅Coppola, Giovanni⋅Geschwind, Daniel⋅Geschwind, Daniel H⋅Landreth, Gary E⋅Landreth, Gary E⋅Snider, William and Snider, William D
Neuron, vol. 69, (no. 1), pp. 105, 2011. | Journal Article
 
Targets of the Peroxisome Proliferator–Activated Receptor γ Agonist Trials for the Prevention of Alzheimer Disease—Reply
Geldmacher, David S⋅Fritsch, Thomas and Landreth, Gary E
Archives of Neurology, vol. 68, (no. 4), pp. 543, 2011-04-11. | Journal Article
 
The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation
Fyffe Maricich, Sharyl L⋅Fyffe-Maricich, Sharyl L⋅Karlo, J C⋅Karlo, J Colleen⋅Landreth, Gary E⋅Landreth, Gary E⋅Miller, Robert H and Miller, Robert H
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 31, (no. 3), pp. 850, 2011-Jan-19. | Journal Article
2010
Deletion of CD14 Attenuates Alzheimer's Disease Pathology by Influencing the Brain's Inflammatory Milieu
Reed-Geaghan, Erin G⋅Reed-Geaghan, Erin G⋅Reed, Quillan W⋅Reed, Quillan W⋅Cramer, Paige E⋅Cramer, Paige E⋅Landreth, Gary E and Landreth, Gary E
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 30, (no. 46), pp. 15373, 2010-Nov-17. | Journal Article
 
Genetic Targeting of ERK1 Suggests a Predominant Role for ERK2 in Murine Pain Models
Alter, Benedict J⋅Alter, Benedict J⋅Zhao, Chengshui⋅Zhao, Chengshui⋅Karim, Farzana⋅Karim, Farzana⋅Landreth, Gary E⋅Landreth, Gary E⋅Gereau, 4th, Robert W and Gereau, Robert W
The Journal of neuroscience : the official journal of the Society for Neuroscience, vol. 30, (no. 34), pp. 11547, 2010-Aug-25. | Journal Article
 
Inflammation, microglia, and Alzheimer's disease.
Cameron, Brent and Landreth, Gary E
Neurobiology of disease, vol. 37, (no. 3), pp. 503-9, 2010/Mar. | Journal Article
 
Microglia and Inflammation in Alzheimer's Disease
Mandrekar-Colucci, Shweta and Landreth, Gary E
CNS and Neurological Disorders, vol. 9, (no. 2), pp. 156-167, 2010. | Journal Article
 
Rosiglitazone monotherapy in mild-to-moderate Alzheimer's disease: results from a randomized, double-blind, placebo-controlled phase III study
Gold, Michael⋅Gold, Michael⋅Alderton, Claire⋅Alderton, Claire⋅Zvartau-Hind, Marina⋅Zvartau-Hind, Marina⋅Egginton, Sally⋅Egginton, Sally⋅Saunders, Ann M⋅Saunders, Ann M⋅Irizarry, Michael⋅Irizarry, Michael⋅Craft, Suzanne⋅Craft, Suzanne⋅Landreth, Gary⋅Landreth, Gary⋅Linnamägi, Ülla⋅Linnamägi, Ulla⋅Sawchak, Sharon and Sawchak, Sharon
Dementia and geriatric cognitive disorders, vol. 30, (no. 2), pp. 146, 2010-00-00. | Journal Article
 
The role of microglia in amyloid clearance from the AD brain.
Lee, C Y and Landreth, Gary E
Journal of neural transmission (Vienna, Austria : 1996), vol. 117, (no. 8), pp. 949-60, 2010/Aug. | Journal Article
2009
Brain-Specific Deletion of Extracellular Signal-Regulated Kinase 2 Mitogen-Activated Protein Kinase Leads to Aberrant Cortical Collagen Deposition
Heffron, Daniel⋅Heffron, Daniel S⋅Landreth, Gary⋅Landreth, Gary E⋅Samuels, Ivy S⋅Samuels, Ivy⋅Mandell, James and Mandell, James W
American Journal of Pathology, The, vol. 175, (no. 6), pp. 2599, 2009. | Journal Article
 
CD14 and Toll-like receptors 2 and 4 are required for fibrillar Aβ-stimulated microglial activation
Reed-Geaghan, Erin G⋅Reed-Geaghan, Erin G⋅Savage, Julie C⋅Savage, Julie C⋅Hise, Amy G⋅Hise, Amy G⋅Landreth, Gary E and Landreth, Gary E
The Journal of Neuroscience, vol. 29, (no. 38), pp. 11992, 2009-09-23. | Journal Article
 
Erk1 and Erk2 Regulate Endothelial Cell Proliferation and Migration during Mouse Embryonic Angiogenesis
Srinivasan, Ruchika⋅Srinivasan, Ruchika⋅Zabuawala, Tahera⋅Zabuawala, Tahera⋅Huang, Hong⋅Huang, Hong⋅Zhang, Jianying⋅Zhang, Jianying⋅Gulati, Parul⋅Gulati, Parul⋅Fernandez, Soledad⋅Fernandez, Soledad⋅Karlo, J Colleen⋅Karlo, J C⋅Landreth, Gary E⋅Landreth, Gary E⋅Leone, Gustavo⋅Leone, Gustavo W⋅Ostrowski, Michael and Ostrowski, Michael C
PloS one, vol. 4, (no. 12), pp. e8283, 2009-Dec-14. | Journal Article
 
Extracellular Signal-Regulated Kinase 1 (ERK1) and ERK2 Play Essential Roles in Osteoblast Differentiation and in Supporting Osteoclastogenesis
Matsushita, Takehiko⋅Matsushita, Takehiko⋅Chan, Yuk⋅Chan, Yuk Y⋅Kawanami, Aya⋅Kawanami, Aya⋅Balmes, Gener⋅Balmes, Gener⋅Landreth, Gary⋅Landreth, Gary E⋅Murakami, Shunichi and Murakami, Shunichi
Molecular and Cellular Biology, vol. 29, (no. 21), pp. 5857, 20091101. | Journal Article
 
MAP'ing CNS Development and Cognition: An ERKsome Process
Samuels, Ivy S⋅Samuels, Ivy S⋅Saitta, Sulagna C⋅Saitta, Sulagna C⋅Landreth, Gary E and Landreth, Gary E
Neuron, vol. 61, (no. 2), pp. 167, 2009. | Journal Article
 
Microglia in Central Nervous System Diseases
Landreth, Gary E
Journal of NeuroImmune Pharmacology, vol. 4, (no. 4), pp. 369-370, 2009. | Journal Article
 
Microglia Mediate the Clearance of Soluble Aβ through Fluid Phase Macropinocytosis
Mandrekar, Shweta⋅Mandrekar, Shweta⋅Jiang, Qingguang⋅Jiang, Qingguang⋅Lee, C Y⋅Lee, C. Y. Daniel⋅Koenigsknecht-Talboo, Jessica⋅Koenigsknecht-Talboo, Jessica⋅Holtzman, David M⋅Holtzman, David M⋅Landreth, Gary E and Landreth, Gary E
The Journal of Neuroscience, vol. 29, (no. 13), pp. 4262, 2009-04-01. | Journal Article