131 Publications (Page 1 of 6)
2020
Glycogenin is Dispensable for Glycogen Synthesis in Human Muscle, and Glycogenin Deficiency Causes Polyglucosan Storage
Visuttijai, Kittichate⋅Hedberg-Oldfors, Carola⋅Thomsen, Christer⋅Glamuzina, Emma⋅Kornblum, Cornelia⋅Tasca, Giorgio⋅Hernandez-Lain, Aurelio⋅Sandstedt, Joakim⋅Dellgren, Göran⋅Roach, Peter and Oldfors, Anders
The Journal of Clinical Endocrinology and Metabolism, vol. 105, (no. 2), pp. 557-566, Feb 2020. | Journal Article
2019
Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation
Mayeuf-Louchart, Alicia⋅Lancel, Steve⋅Sebti, Yasmine⋅Pourcet, Benoit⋅Loyens, Anne⋅Delhaye, Stéphane⋅Duhem, Christian⋅Beauchamp, Justine⋅Ferri, Lise⋅Thorel, Quentin⋅Boulinguiez, Alexis⋅Zecchin, Mathilde⋅Dubois-Chevalier, Julie⋅Eeckhoute, Jérôme⋅Vaughn, Logan T⋅Roach, Peter J⋅Dani, Christian⋅Pederson, Bartholomew A⋅Vincent, Stéphane D⋅Staels, Bart and Duez, Hélène
Cell Reports, vol. 29, (no. 6), pp. 1418.e6, 2019-11-05. | Journal Article
 
Targeting Pathogenic Lafora Bodies in Lafora Disease Using an Antibody-Enzyme Fusion
Brewer, M. Kathryn⋅Uittenbogaard, Annette⋅Austin, Grant L⋅Segvich, Dyann M⋅DePaoli-Roach, Anna⋅Roach, Peter J⋅McCarthy, John J⋅Simmons, Zoe R⋅Brandon, Jason A⋅Zhou, Zhengqiu⋅Zeller, Jill⋅Young, Lyndsay E.A⋅Sun, Ramon C⋅Pauly, James R⋅Aziz, Nadine M⋅Hodges, Bradley L⋅McKnight, Tracy R⋅Armstrong, Dustin D and Gentry, Matthew S
Cell Metabolism, vol. 30, (no. 4), pp. 705.e6, 2019-10-01. | Journal Article
2018
Glycogen Enhancement Augments Overload-Induced Protein Synthesis, Growth, and Myogenesis in Aged Skeletal Muscle.: 2007 Board #268 May 31 2: 00 PM - 3: 30 PM
Lawrence, Marcus⋅Lawrence, Marcus⋅Huot, Josh⋅Huot, Josh⋅Peck, Bailey⋅Peck, Bailey⋅Wen, Yuan⋅Wen, Yuan⋅Shields, Michael⋅Shields, Michael⋅Madhiwala, Raahil⋅Madhiwala, Raahil⋅Skurat, Alexander⋅Skurat, Alexander⋅Roach, Peter⋅Roach, Peter⋅Kane, Eric⋅Kane, Eric⋅Reitzel, Adam⋅Reitzel, Adam⋅Miller, Benjamin⋅Miller, Benjamin⋅Hamilton, Karyn⋅Hamilton, Karyn⋅Arthur, Susan⋅Arthur, Susan⋅Gordon, Scott and Gordon, Scott
Medicine & Science in Sports & Exercise, vol. 50, (no. 5S Suppl 1), pp. 488, 2018-May. | Journal Article
 
Lafora disease offers a unique window into neuronal glycogen metabolism
Gentry, Matthew S⋅Guinovart, Joan J⋅Minassian, Berge A⋅Roach, Peter J and Serratosa, Jose M
The Journal of biological chemistry, vol. 293, (no. 19), pp. 7125, 2018-05-11. | Journal Article
2017
Lack of liver glycogen causes hepatic insulin resistance and steatosis in mice
Irimia, Jose M⋅Irimia, Jose M⋅Meyer, Catalina M⋅Meyer, Catalina M⋅Segvich, Dyann M⋅Segvich, Dyann M⋅Surendran, Sneha⋅Surendran, Sneha⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Morral, Nuria⋅Morral, Nuria⋅Roach, Peter J and Roach, Peter J
The Journal of biological chemistry, vol. 292, (no. 25), pp. 10464, 2017-06-23. | Journal Article
 
Redox Switch for the Inhibited State of Yeast Glycogen Synthase Mimics Regulation by Phosphorylation
Mahalingan, Krishna K⋅Mahalingan, Krishna K⋅Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Roach, Peter J⋅Roach, Peter J⋅Hurley, Thomas D and Hurley, Thomas D
Biochemistry, vol. 56, (no. 1), pp. 188, 20170110. | Journal Article
2016
Gain of function AMP-activated protein kinase gamma 3 mutation (AMPK gamma 3(R200Q)) in pig muscle increases glycogen storage regardless of AMPK activation
Scheffler, Tracy⋅Park, Sungkwon⋅Roach, Peter and Gerrard, David
2016-06. | Journal Article
 
Gain of function AMP-activated protein kinase γ 3 mutation (AMPKγ 3R200Q ) in pig muscle increases glycogen storage regardless of AMPK activation
Scheffler, Tracy L⋅Scheffler, Tracy L⋅Park, Sungkwon⋅Park, Sungkwon⋅Roach, Peter J⋅Roach, Peter J⋅Gerrard, David E and Gerrard, David E
Physiological Reports, vol. 4, (no. 11), pp. np, 2016-06-00. | Journal Article
 
Incorporation of phosphate into glycogen by glycogen synthase
Contreras, Christopher J⋅Contreras, Christopher J⋅Segvich, Dyann M⋅Segvich, Dyann M⋅Mahalingan, Krishna⋅Mahalingan, Krishna⋅Chikwana, Vimbai M⋅Chikwana, Vimbai M⋅Kirley, Terence L⋅Kirley, Terence L⋅Hurley, Thomas D⋅Hurley, Thomas D⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Roach, Peter J and Roach, Peter J
Archives of Biochemistry and Biophysics, vol. 597, pp. 29, 2016-05-01. | Journal Article
2015
Glycogen Phosphomonoester Distribution in Mouse Models of the Progressive Myoclonic Epilepsy, Lafora Disease
DePaoli-Roach, Anna A⋅Contreras, Christopher J⋅Segvich, Dyann M⋅Heiss, Christian⋅Ishihara, Mayumi⋅Azadi, Parastoo and Roach, Peter J
The Journal of biological chemistry, vol. 290, (no. 2), pp. 850, 2015-Jan-09. | Journal Article
 
Glycogen phosphorylation and Lafora disease.
Roach, Peter J
Molecular aspects of medicine, vol. 46, pp. 78-84, December 2015. | Journal Article
 
Muscle Glycogen Remodeling and Glycogen Phosphate Metabolism following Exhaustive Exercise of Wild Type and Laforin Knockout Mice
Irimia, Jose M⋅Tagliabracci, Vincent S⋅Meyer, Catalina M⋅Segvich, Dyann M⋅DePaoli-Roach, Anna A and Roach, Peter J
The Journal of biological chemistry, vol. 290, (no. 37), pp. 22698, 2015-Sep-11. | Journal Article
2014
Sterol regulatory element-binding protein-1 (SREBP-1) is required to regulate glycogen synthesis and gluconeogenic gene expression in mouse liver.
Ruiz, Rafaela⋅Ruiz, Rafaela⋅Ruiz, R.⋅Jideonwo, Victoria⋅Jideonwo, Victoria⋅Jideonwo, V.⋅Ahn, Miwon⋅Ahn, Miwon⋅Ahn, M.⋅Surendran, S.⋅Surendran, Sneha⋅Surendran, Sneha⋅Tagliabracci, Vincent S⋅Tagliabracci, Vincent S⋅Tagliabracci, V.S.⋅Hou, Yongyong⋅Hou, Y.⋅Hou, Yongyong⋅Gamble, Aisha⋅Gamble, Aisha⋅Gamble, A.⋅Kerner, J.⋅Kerner, Janos⋅Kerner, Janos⋅Irimia-Dominguez, J.M.⋅Irimia-Dominguez, José M⋅Irimia-Dominguez, José M⋅Puchowicz, M.A.⋅Puchowicz, Michelle A⋅Puchowicz, Michelle A⋅DePaoli-Roach, A.⋅Depaoli-Roach, Anna⋅DePaoli-Roach, Anna⋅DePaoli-Roach, Anna⋅Hoppel, Charles⋅Hoppel, C.⋅Hoppel, Charles⋅Roach, P.⋅Roach, Peter⋅Roach, Peter⋅Morral, Núria⋅Morral, Nuria and Morral, N.
The Journal of biological chemistry, vol. 289, (no. 9), pp. 5510-5517, February 28, 2014. | Journal Article
2013
Hepatic Glucose Metabolism in Late Pregnancy: Normal Versus High-Fat and -Fructose Diet
Coate, Katie C⋅Coate, Katie C⋅Smith, Marta S⋅Smith, Marta S⋅Shiota, Masakazu⋅Shiota, Masakazu⋅Irimia, Jose M⋅Irimia, Jose M⋅Roach, Peter J⋅Roach, Peter J⋅Farmer, Ben⋅Farmer, Ben⋅Williams, Phillip E⋅Williams, Phillip E⋅Moore, Mary C and Moore, Mary Courtney
Diabetes, vol. 62, (no. 3), pp. 761, 2013-Mar. | Journal Article
 
Inhibiting glycogen synthesis prevents lafora disease in a mouse model
Pederson, Bartholomew A⋅Pederson, Bartholomew A⋅Turnbull, Julie⋅Turnbull, Julie⋅Epp, Jonathan R⋅Epp, Jonathan R⋅Weaver, Staci A⋅Weaver, Staci A⋅Zhao, Xiaochu⋅Zhao, Xiaochu⋅Pencea, Nela⋅Pencea, Nela⋅Roach, Peter J⋅Roach, Peter J⋅Frankland, Paul W⋅Frankland, Paul W⋅Ackerley, Cameron A⋅Ackerley, Cameron A⋅Minassian, Berge A and Minassian, Berge
Annals of Neurology, vol. 74, (no. 2), pp. 300, August 2013. | Journal Article
 
Liver Glycogen Loading Dampens Glycogen Synthesis Seen in Response to Either Hyperinsulinemia or Intraportal Glucose Infusion
Winnick, Jason J⋅Winnick, Jason⋅An, Zhibo⋅An, Zhibo⋅Kraft, Guillaume⋅Kraft, Guillaume⋅Ramnanan, Christopher J⋅Ramnanan, Christopher J⋅Irimia, Jose M⋅Irimia, Jose M⋅Smith, Marta⋅Smith, Marta⋅Lautz, Margaret⋅Lautz, Margaret⋅Roach, Peter J⋅Roach, Peter J⋅Cherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 62, (no. 1), pp. 101, 2013-Jan. | Journal Article
 
Portal Vein Glucose Entry Triggers a Coordinated Cellular Response That Potentiates Hepatic Glucose Uptake and Storage in Normal but Not High-Fat/High-Fructose-Fed Dogs
Coate, Katie C⋅Coate, Katie C⋅Kraft, Guillaume⋅Kraft, Guillaume⋅Irimia, Jose M⋅Irimia, Jose M⋅Smith, Marta S⋅Smith, Marta S⋅Farmer, Ben⋅Farmer, Ben⋅Neal, Doss W⋅Neal, Doss W⋅Roach, Peter J⋅Roach, Peter J⋅Shiota, Masakazu⋅Shiota, Masakazu⋅Cherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 62, (no. 2), pp. 400, 2013-Feb. | Journal Article
 
Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase
Chikwana, Vimbai M⋅Chikwana, Vimbai⋅Khanna, May⋅Khanna, May⋅Baskaran, Sulochanadevi⋅Baskaran, Sulochanadevi⋅Tagliabracci, Vincent S⋅Tagliabracci, Vincent⋅Contreras, Christopher J⋅Contreras, Christopher⋅DePaoli-Roach, Anna⋅Depaoli Roach, Anna A⋅DePaoli-Roach, Anna⋅Roach, Peter⋅Roach, Peter J⋅Hurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 110, (no. 52), pp. 20981, 20131224. | Journal Article
2012
A Cyclic Guanosine Monophosphate-Dependent Pathway Can Regulate Net Hepatic Glucose Uptake in Vivo
An, Zhibo⋅An, Zhibo⋅Winnick, Jason J⋅Winnick, Jason J⋅Moore, Mary C⋅Moore, Mary C⋅Farmer, Ben⋅Farmer, Ben⋅Smith, Marta⋅Smith, Marta⋅Irimia, Jose M⋅Irimia, Jose M⋅Roach, Peter J⋅Roach, Peter J⋅Cherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 61, (no. 10), pp. 2441, 2012-Oct. | Journal Article
 
Glycogen and its metabolism: some new developments and old themes
Roach, Peter J⋅Roach, Peter J⋅Depaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Hurley, Thomas D⋅Hurley, Thomas D⋅Tagliabracci, Vincent S and Tagliabracci, Vincent S
The Biochemical journal, vol. 441, (no. 3), pp. 787, 2012-Feb-01. | Journal Article
 
Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity
DePaoli-Roach, A.A.⋅DePaoli-Roach, Anna A⋅DePaoli-Roach, Anna A⋅Depaoli Roach, Anna A⋅Segvich, Dyann M⋅Segvich, Dyann M⋅Segvich, D.M.⋅Meyer, C.M.⋅Meyer, Catalina M⋅Meyer, Catalina M⋅Rahimi, Yasmeen⋅Rahimi, Y.⋅Rahimi, Yasmeen⋅Worby, Carolyn A⋅Worby, Carolyn A⋅Worby, C.A.⋅Gentry, Matthew⋅Gentry, M.S.⋅Gentry, Matthew S⋅Roach, Peter J⋅Roach, P.J. and Roach, Peter J
Human Molecular Genetics, vol. 21, (no. 7), pp. 1610, 20120401. | Journal Article
2011
AMPK -> ULK1 -> autophagy.
Roach, Peter J
Molecular and cellular biology, vol. 31, (no. 15), pp. 3082-4, 2011/Aug. | Journal Article
 
Are there errors in glycogen biosynthesis and is laforin a repair enzyme?
Roach, Peter J and Roach, Peter J
FEBS Letters, vol. 585, (no. 20), pp. 3218, 2011-10-20. | Journal Article
 
Hepatic Glycogen Supercompensation Activates AMP-Activated Protein Kinase, Impairs Insulin Signaling, and Reduces Glycogen Deposition in the Liver
Winnick, Jason J⋅Winnick, Jason J⋅An, Zhibo⋅An, Zhibo⋅Ramnanan, Christopher J⋅Ramnanan, Christopher J⋅Smith, Marta⋅Smith, Marta⋅Irimia, Jose M⋅Irimia, Jose M⋅Neal, Doss W⋅Neal, Doss W⋅Moore, Mary Courtney⋅Moore, Mary C⋅Roach, Peter J⋅Roach, Peter J⋅Cherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 60, (no. 2), pp. 407, 2011-Feb. | Journal Article