131 Publications (Page 2 of 6)
2011
PTG depletion removes Lafora bodies and rescues the fatal epilepsy of Lafora disease.
Turnbull, JulieDepaoli Roach, Anna AZhao, XiaochuCortez, Miguel APencea, NelaTiberia, EricaPiliguian, MarkRoach, Peter JWang, PeixiangAckerley, Cameron and Minassian, Berge
PLoS genetics, vol. 7, (no. 4), pp. e1002037, 2011/Apr. | Journal Article
 
Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1
Jiang, SixinJiang, SixinJiang, SixinWells, Clark DWells, Clark DWells, Clark DRoach, Peter JRoach, Peter J and Roach, Peter J
Biochemical and Biophysical Research Communications, vol. 413, (no. 3), pp. 425, 2011. | Journal Article
2010
A Soluble Guanylate Cyclase-Dependent Mechanism Is Involved in the Regulation of Net Hepatic Glucose Uptake by Nitric Oxide in Vivo
An, ZhiboAn, ZhiboWinnick, Jason JWinnick, Jason JFarmer, BenFarmer, BenNeal, DossNeal, DossLautz, MargaretLautz, MargaretIrimia, Jose MIrimia, Jose MRoach, Peter JRoach, Peter JCherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 59, (no. 12), pp. 3007, 2010-Dec. | Journal Article
 
Genetic Depletion of the Malin E3 Ubiquitin Ligase in Mice Leads to Lafora Bodies and the Accumulation of Insoluble Laforin
Depaoli Roach, Anna ADePaoli-Roach, Anna ADePaoli-Roach, Anna ATagliabracci, Vincent STagliabracci, Vincent SSegvich, Dyann MSegvich, Dyann MMeyer, Catalina MMeyer, Catalina MIrimia, Jose MIrimia, Jose MRoach, Peter J and Roach, Peter J
The Journal of biological chemistry, vol. 285, (no. 33), pp. 25381, 2010-Aug-13. | Journal Article
 
Insulin-induced hypoglycemia increases hepatic sensitivity to glucagon in dogs
Rivera, NoeliaRivera, NoeliaRamnanan, Christopher JRamnanan, Christopher JAn, ZhiboAn, ZhiboFarmer, TiffanyFarmer, TiffanySmith, MartaSmith, MartaFarmer, BenFarmer, BenIrimia, Jose MIrimia, Jose MSnead, WandaSnead, WandaLautz, MargaretLautz, MargaretRoach, Peter JRoach, Peter JCherrington, Alan D and Cherrington, Alan D
The Journal of clinical investigation, vol. 120, (no. 12), pp. 4435, 2010-Dec. | Journal Article
 
Molecular Characterization of Insulin-Mediated Suppression of Hepatic Glucose Production In Vivo
Ramnanan, Christopher JRamnanan, Christopher JEdgerton, Dale SEdgerton, Dale SRivera, NoeliaRivera, NoeliaIrimia-Dominguez, JoseIrimia-Dominguez, JoseFarmer, BenFarmer, BenNeal, Doss WNeal, Doss WLautz, MargaretLautz, MargaretDonahue, E. PDonahue, E PatrickMeyer, Catalina MMeyer, Catalina MRoach, Peter JRoach, Peter JCherrington, Alan D and Cherrington, Alan D
Diabetes, vol. 59, (no. 6), pp. 1311, 2010-Jun. | Journal Article
 
Regulation of glycogen metabolism in yeast and bacteria
Wilson, Wayne ARoach, Peter JMontero, ManuelBaroja-Fernandez, EdurneMunoz, Francisco JEydallin, GustavoViale, Alejandro M and Pozueta-Romero, Javier
FEMS microbiology reviews., vol. 34, (no. 6), pp. 952-985, 2010. | Journal Article
 
Restoration of muscle functionality by genetic suppression of glycogen synthesis in a murine model of Pompe disease
Douillard-Guilloux, GaelleRaben, NinaTakikita, ShoichiFerry, ArnaudVignaud, AlbanGuillet-Deniau, IsabelleFavier, MarylineThurberg, Beth LRoach, Peter JCaillaud, Catherine and Richard, Emmanuel
Human Molecular Genetics, vol. 19, (no. 4), pp. 684-696, 2010. | Journal Article
 
Structural basis for glucose-6-phosphate activation of glycogen synthase
Baskaran, SulochanadeviBaskaran, SulochanadeviRoach, PeterRoach, Peter JDepaoli Roach, Anna ADePaoli-Roach, AnnaDePaoli-Roach, Anna AHurley, Thomas D and Hurley, Thomas
Proceedings of the National Academy of Sciences of the United States of America, vol. 107, (no. 41), pp. 17568, 20101012. | Journal Article
 
The subcellular localization of yeast glycogen synthase is dependent upon glycogen content
Wilson, Wayne ABoyer, Michael PDavis, Keri DBurke, Michael and Roach, Peter J
Canadian Journal of Microbiology/Revue Canadienne de Microbiologie, vol. 56, (no. 5), pp. 408-420, 2010. | Journal Article
2009
Characterization of mouse UDP-glucose pyrophosphatase, a Nudix hydrolase encoded by the Nudt14 gene
Heyen, Candy AHeyen, Candy ATagliabracci, Vincent STagliabracci, Vincent SZhai, LanminZhai, LanminRoach, Peter J and Roach, Peter J
Biochemical and Biophysical Research Communications, vol. 390, (no. 4), pp. 1418, 2009. | Journal Article
2008
Abnormal Metabolism of Glycogen Phosphate as a Cause for Lafora Disease
Tagliabracci, VincentTagliabracci, Vincent SGirard, JeanGirard, Jean MSegvich, DyannSegvich, DyannMeyer, CatalinaMeyer, CatalinaTurnbull, JulieTurnbull, JulieZhao, XiaochuZhao, XiaochuMinassian, BergeMinassian, BergeDePaoli-Roach, AnnaDepaoli Roach, Anna ARoach, Peter J and Roach, Peter
Journal of Biological Chemistry, vol. 283, (no. 49), pp. 33825, 20081205. | Journal Article
 
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
Savage, David AZhai, LanminRavikumar, BalasubramanianCheol, S.C.Choi, Cheol SSnaar, Johanna EMcGuire, Amanda CWou, Sung-EunMedina-Gomez, GemmaKim, SheeneBock, Cheryl BSegvich, Dyann MVidal Puig, AntonioSolanky, BhavanaWareham, Nicholas JDeelchand, DineshShulman, Gerald IKarpe, FredrikTaylor, RoyPederson, Bartholomew ARoach, Peter JO’Rahilly, S.O'Rahilly, StephenDepaoli Roach, Anna A and DePaoli-Roach, A.A.
PLoS medicine, vol. 5, (no. 1), pp. e27, 2008/Jan/29. | Journal Article
 
Correction: A Prevalent Variant in PPP1R3A Impairs Glycogen Synthesis and Reduces Muscle Glycogen Content in Humans and Mice
Cheung, A.M.Savage, David BDavid, B.S.Zhai, L.Zhai, LanminTile, L.Ravikumar, BalasubramanianRavikumar, B.Lee, Y.Choi, Cheol SooTomlinson, G.Choi, C.S.Hawker, G.Snaar, J.E.Snaar, Johanna EScher, J.McGuire, A.C.McGuire, Amanda CWou, Sung-EunWou, S.-E.Hu, H.Vieth, R.Medina-Gomez, G.Medina-Gomez, GemmaKim, SheeneThompson, L.Kim, S.Bock, C.B.Jamal, S.Bock, Cheryl BJosse, R.Segvich, Dyann MSegvich, D.M.Solanky, B.Solanky, BhavanaDeelchand, D.Deelchand, DineshVidal-Puig, A.Vidal-Puig, AntonioWareham, Nicholas JWareham, N.J.Shulman, Gerald IShulman, G.I.Karpe, F.Karpe, FredrikTaylor, R.Taylor, RoyPederson, Bartholomew APederson, B.A.Roach, Peter JRoach, P.J.O’Rahilly, S.O'Rahilly, StephenDePaoli-Roach, Anna A and DePaoli-Roach, A.A.
PLoS Medicine, vol. 5, (no. 12), pp. e246, 2008-12-23. | Journal Article
2007
Glycogen metabolism in tissues from a mouse model of Lafora disease
Wang, WeiWang, WeiLohi, HannesLohi, HannesSkurat, Alexander VSkurat, Alexander VDePaoli-Roach, Anna ADepaoli Roach, Anna ADePaoli-Roach, Anna AMinassian, Berge AMinassian, Berge ARoach, Peter J and Roach, Peter J
Archives of Biochemistry and Biophysics, vol. 457, (no. 2), pp. 269, 2007. | Journal Article
 
John C. Lawrence, Jr. (1949–2006)
Roach, Peter J
Cell Metabolism, vol. 5, (no. 5), pp. 330, 2007. | Journal Article
 
Laforin Is a Glycogen Phosphatase, Deficiency of Which Leads to Elevated Phosphorylation of Glycogen in vivo
Tagliabracci, VincentDelgado Escueta, AntonioTagliabracci, Vincent STurnbull, JulieTurnbull, JulieWang, WeiWang, WeiGirard, Jean-MarieGirard, Jean-MarieZhao, XiaochuZhao, XiaochuSkurat, AlexanderSkurat, Alexander VDelgado-Escueta, AntonioDelgado-Escueta, Antonio VMinassian, BergeMinassian, BergeDepaoli Roach, Anna ADePaoli-Roach, AnnaRoach, Peter J and Roach, Peter
Proceedings of the National Academy of Sciences of the United States of America, vol. 104, (no. 49), pp. 19266, 20071204. | Journal Article
2006
Direct detection of glycogenin reaction products during glycogen initiation
Hurley, Thomas DHurley, Thomas DWalls, ChadWalls, ChadBennett, John RBennett, John RRoach, Peter JRoach, Peter JWang, Mu and Wang, Mu
Biochemical and Biophysical Research Communications, vol. 348, (no. 2), pp. 378, 2006. | Journal Article
 
Gene expression profiling of mice with genetically modified muscle glycogen content
Parker, Gretchen EParker, Gretchen EPederson, Bartholomew APederson, Bartholomew AObayashi, MarikoObayashi, MarikoSchroeder, Jill MSchroeder, Jill MHarris, Robert AHarris, Robert ARoach, Peter J and Roach, Peter J
The Biochemical journal, vol. 395, (no. 1), pp. 145, 2006-Apr-01. | Journal Article
 
Interaction between glycogenin and glycogen synthase
Skurat, Alexander VSkurat, Alexander VDietrich, Amy DDietrich, Amy DRoach, Peter J and Roach, Peter J
Archives of Biochemistry and Biophysics, vol. 456, (no. 1), pp. 97, 2006. | Journal Article
 
Relationship between glycogen accumulation and the laforin dual specificity phosphatase
Wang, WeiWang, WeiParker, Gretchen EParker, Gretchen ESkurat, Alexander VSkurat, Alexander VRaben, NinaRaben, NinaDepaoli Roach, Anna ADePaoli-Roach, Anna ADePaoli-Roach, Anna ARoach, Peter J and Roach, Peter J
Biochemical and Biophysical Research Communications, vol. 350, (no. 3), pp. 592, 2006. | Journal Article
2005
Biochemical characterization of Neurospora crassa glycogenin (GNN), the self-glucosylating initiator of glycogen synthesis
de Paula, Renato MWilson, Wayne ARoach, Peter JTerenzi, Héctor F and Bertolini, Maria C
FEBS Letters, vol. 579, (no. 10), pp. 2208-2214, 2005. | Journal Article
 
Control of mammalian glycogen synthase by PAS kinase
Wilson, WayneWilson, Wayne ASkurat, Alexander VSkurat, AlexanderProbst, BrandonProbst, BrandonPaoli-Roach, Annade Paoli-Roach, AnnaRoach, Peter JRoach, PeterRutter, Jared and Rutter, Jared
Proceedings of the National Academy of Sciences, USA, vol. 102, (no. 46), pp. 16596-16601, 2005. | Journal Article
 
Exercise Capacity of Mice Genetically Lacking Muscle Glycogen Synthase: IN MICE, MUSCLE GLYCOGEN IS NOT ESSENTIAL FOR EXERCISE.
Pederson, Bartholomew ACope, Carlie RSchroeder, Jill MSmith, Micah WIrimia, José MThurberg, Beth LDepaoli Roach, Anna A and Roach, Peter J
Journal of biological chemistry., vol. 280, (no. 17), pp. 17260-17265, 2005. | Journal Article
 
Glucose Metabolism in Mice Lacking Muscle Glycogen Synthase
Pederson, Bartholomew ASchroeder, Jill MParker, Gretchen ESmith, Micah WDepaoli Roach, Anna A and Roach, Peter J
Diabetes, vol. 54, (no. 12), pp. 3466-3473, 2005. | Journal Article